-
1
-
-
84858225391
-
Alzheimer's disease facts and figures
-
Alzheimer's Association
-
Alzheimer's Association (2012) Alzheimer's disease facts and figures. Alzheimers Dement 8, 131-168
-
(2012)
Alzheimers Dement
, vol.8
, pp. 131-168
-
-
-
2
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
Iqbal K, Liu F, Gong CX, Alonso Adel C, Grundke-Iqbal I (2009) Mechanisms of tau-induced neurodegeneration. Acta Neuropathol 118, 53-69
-
(2009)
Acta Neuropathol
, vol.118
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso Adel, C.4
Grundke-Iqbal, I.5
-
3
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT (1992) Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42, 631-639
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
4
-
-
84855304100
-
Cerebrospinal fluid levels of 2277;-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia
-
Buchhave P, Minthon L, Zetterberg H, Wallin K, Blennow K, Hansson O (2012) Cerebrospinal fluid levels of 2277;-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia. Arch Gen Psychiatry 69, 98-106
-
(2012)
Arch Gen Psychiatry
, vol.69
, pp. 98-106
-
-
Buchhave, P.1
Minthon, L.2
Zetterberg, H.3
Wallin, K.4
Blennow, K.5
Hansson, O.6
-
5
-
-
19744362332
-
Alzheimer's disease: A tangled issue
-
DOI 10.1016/S1359-6446(05)03482-3, PII S1359644605034823
-
Benson A (2005) Alzheimer's disease: A tangled issue. Drug Discov Today 10, 749-751 (Pubitemid 40744917)
-
(2005)
Drug Discovery Today
, vol.10
, Issue.11
, pp. 749-751
-
-
Benson, A.1
-
7
-
-
67650473070
-
Drug development for Alzheimer's disease: Where are we now and where are we headed?
-
Sabbagh M (2009) Drug development for Alzheimer's disease: Where are we now and where are we headed? Am J Geriatr Pharmacother 7, 167-185
-
(2009)
Am J Geriatr Pharmacother
, vol.7
, pp. 167-185
-
-
Sabbagh, M.1
-
8
-
-
84874289532
-
-
America's Biopharmaceutical Research Companies
-
America's Biopharmaceutical Research Companies (2012) Medicines in Development: Alzheimer's Disease, http:// phrma.org/sites/default/files/422/ alzheimers2012.pdf
-
(2012)
Medicines in Development: Alzheimer's Disease
-
-
-
9
-
-
0141738373
-
CSF markers for incipient Alzheimer's disease
-
DOI 10.1016/S1474-4422(03)00530-1
-
Blennow K, Hampel H (2003) CSF markers for incipient Alzheimer's disease. Lancet Neurol 2, 605-613 (Pubitemid 37162569)
-
(2003)
Lancet Neurology
, vol.2
, Issue.10
, pp. 605-613
-
-
Blennow, K.1
Hampel, H.2
-
10
-
-
84868683533
-
Evaluation of 11C N-methyl lansoprazole as a radiopharmaceutical for PET imaging of tau neurofibrillary tangles
-
Shao X, Carpenter GM, Desmond TJ, Sherman P, Quesada CA, Fawaz M, Brooks AF, Kilbourn MR, Albin RL, Frey KA, Scott PJH (2012) Evaluation of 11C N-methyl lansoprazole as a radiopharmaceutical for PET imaging of tau neurofibrillary tangles. ACS Med Chem Lett 3, 936-941
-
(2012)
ACS Med Chem Lett
, vol.3
, pp. 936-941
-
-
Shao, X.1
Carpenter, G.M.2
Desmond, T.J.3
Sherman, P.4
Quesada, C.A.5
Fawaz, M.6
Brooks, A.F.7
Kilbourn, M.R.8
Albin, R.L.9
Frey, K.A.10
Pjh, S.11
-
11
-
-
84863748837
-
The challenges of tau imaging
-
Villemagne V, Furumoto S, Fodero-Tavoletti M, Harada R, Mulligan RS, Kudo Y, Masters CL, Yanai K, Rowe CC, Okamura N (2012) The challenges of tau imaging. Future Neurol 7, 409-421
-
(2012)
Future Neurol
, vol.7
, pp. 409-421
-
-
Villemagne, V.1
Furumoto, S.2
Fodero-Tavoletti, M.3
Harada, R.4
Mulligan, R.S.5
Kudo, Y.6
Masters, C.L.7
Yanai, K.8
Rowe, C.C.9
Okamura, N.10
-
12
-
-
84865149006
-
Synthesis and biological evaluation of novel oxindole derivatives for imaging neurofibrillary tangles in Alzheimer's disease
-
Watanabe H, Ono M, Kimura H, Matsumura K, Yoshimura M, Okamoto Y, Ihara M, Takahashi R, Saji H (2012) Synthesis and biological evaluation of novel oxindole derivatives for imaging neurofibrillary tangles in Alzheimer's disease. Bioorg Med Chem Lett 22, 5700-5703
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 5700-5703
-
-
Watanabe, H.1
Ono, M.2
Kimura, H.3
Matsumura, K.4
Yoshimura, M.5
Okamoto, Y.6
Ihara, M.7
Takahashi, R.8
Saji, H.9
-
13
-
-
84874287376
-
In vivo tau imaging in Alzheimer's disease
-
Villemagne V, Furumoto S, Fodero-Tavoletti M, Mulligan R, Hodges J, Kudo Y, Masters C, Yanai K, Rowe C, Okamura N (2012) In vivo tau imaging in Alzheimer's disease. J Nucl Med 53 (Suppl 1), 36
-
(2012)
J Nucl Med
, vol.53
, Issue.SUPPL. 1
, pp. 36
-
-
Villemagne, V.1
Furumoto, S.2
Fodero-Tavoletti, M.3
Mulligan, R.4
Hodges, J.5
Kudo, Y.6
Masters, C.7
Yanai, K.8
Rowe, C.9
Okamura, N.10
-
14
-
-
84865602256
-
A highly selective and specific PET tracer for imaging of tau pathologies
-
Zhang W, Arteaga J, Cashion DK, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Szardenings AK, Wang E, Walsh JC, Xia C, Yu C, Zhao T, Kolb HC (2012) A highly selective and specific PET tracer for imaging of tau pathologies. J Alzheimers Dis 31, 601-612
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 601-612
-
-
Zhang, W.1
Arteaga, J.2
Cashion, D.K.3
Chen, G.4
Gangadharmath, U.5
Gomez, L.F.6
Kasi, D.7
Lam, C.8
Liang, Q.9
Liu, C.10
Mocharla, V.P.11
Mu, F.12
Sinha, A.13
Szardenings, A.K.14
Wang, E.15
Walsh, J.C.16
Xia, C.17
Yu, C.18
Zhao, T.19
Kolb, H.C.20
more..
-
15
-
-
0016823810
-
Mini-mental state: A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198
-
(1975)
J Psychiatr Res
, vol.12
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
16
-
-
0025863618
-
Neuropathological staging of Alzheimer-related changes
-
Braak H, Braak E (1991) Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 82, 239-259
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
17
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
DOI 10.1007/s00401-006-0127-z
-
Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K (2006) Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol 112, 389-404 (Pubitemid 44469160)
-
(2006)
Acta Neuropathologica
, vol.112
, Issue.4
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Tredici, K.5
-
18
-
-
77953937194
-
In vivo imaging of amyloid deposition in Alzheimer's disease using the novel radioligand 18FAV-45 (Florbetapir F 18)
-
Wong DF, Rosenberg PB, Zhou Y, Kumar A, Raymont V, Ravert HT, Dannals RF, Nandi A, Bracsic JR, Ye W, Hilton J, Lyketsos C, Kung HF, Joshi AD, Skovronsky DM, Pontecorvo MJ (2010) In vivo imaging of amyloid deposition in Alzheimer's disease using the novel radioligand 18FAV-45 (Florbetapir F 18). J Nucl Med 51, 913-920
-
(2010)
J Nucl Med
, vol.51
, pp. 913-920
-
-
Wong, D.F.1
Rosenberg, P.B.2
Zhou, Y.3
Kumar, A.4
Raymont, V.5
Ravert, H.T.6
Dannals, R.F.7
Nandi, A.8
Bracsic, J.R.9
Ye, W.10
Hilton, J.11
Lyketsos, C.12
Kung, H.F.13
Joshi, A.D.14
Skovronsky, D.M.15
Pontecorvo, M.J.16
-
19
-
-
62449341361
-
Consideration of optimal time window for Pittsburgh compound B PET summed uptake measurements
-
McNamee RL, Yee SH, Price JC, Klunk WE, Rosario B, Weissfeld L, Ziolko S, Berginc M, Lopresti B, DeKosky S, Mathis CA (2009) Consideration of optimal time window for Pittsburgh compound B PET summed uptake measurements. J Nucl Med 50, 348-355
-
(2009)
J Nucl Med
, vol.50
, pp. 348-355
-
-
McNamee, R.L.1
Yee, S.H.2
Price, J.C.3
Klunk, W.E.4
Rosario, B.5
Weissfeld, L.6
Ziolko, S.7
Berginc, M.8
Lopresti, B.9
Dekosky, S.10
Mathis, C.A.11
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