Disjoint combinations profiling (DCP): A new method for the prediction of antibody CDR conformation from sequence

PeerJ

Volumn 2014, Issue 1, 2014, Pages

  Nikoloudis, Dimitris ^a   Pitts, Jim E ^a   Saldanha, José W ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Antibody engineering; Blind test; Canonical templates; CDR conformation; CDR H3 sequence rules; Conformational prediction; DCP; Humanisation; Prediction from sequence

Indexed keywords

ACCURACY; ARTICLE; CANONICAL ANALYSIS; COMPLEMENTARITY DETERMINING REGION; CONCEPTUAL FRAMEWORK; CONFORMATIONAL TRANSITION; DNA FINGERPRINTING; HUMAN; PERFORMANCE; PREDICTION; PROTEIN ENGINEERING; SEQUENCE ANALYSIS; VALIDATION PROCESS;

EID: 84903830732     PISSN: None     EISSN: 21678359     Source Type: Journal    
DOI: 10.7717/peerj.455     Document Type: Article

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