Antiarthritic and chondroprotective activity of Lakshadi Guggul in novel alginate-enclosed chitosan calcium phosphate nanocarriers

Nanomedicine

Volumn 9, Issue 6, 2014, Pages 819-837

  Samarasinghe, Rasika M ^a   Kanwar, Rupinder K ^a   Kumar, Kuldeep ^b   Kanwar, Jagat R ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b PG Scholars Ayurvedic College   (India)

Author keywords

alginate; anti inflammatory; antiarthritic; chitosan; Cissus quadrangularis; collagen induced arthritis; Lakshadi Guggul; nanocarrier; oral delivery; osteoarthritis

Indexed keywords

ALGINIC ACID; AYURVEDIC DRUG; CALCIUM PHOSPHATE; CHITOSAN; CISSUS QUADRANGULARIS EXTRACT; COLLAGENASE 3; CYCLOOXYGENASE 2; GAMMA INTERFERON; GELATINASE B; GLYCOSAMINOGLYCAN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 16; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 27; INTERLEUKIN 5; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; LACTATE DEHYDROGENASE; LAKSHADI GUGGUL; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 15; NANOCARRIER; NITRIC OXIDE; PROSTAGLANDIN E2; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; DRUG CARRIER; GLUCURONIC ACID; GUGGUL; GUGGULU EXTRACT; HEXURONIC ACID; NANOMATERIAL; PLANT EXTRACT; PLANT GUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARTHRITIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL PROLIFERATION; CELL VIABILITY; CHONDROPROTECTION; CISSUS QUADRANGULARIS; COCULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ACTIVITY; DRUG POTENCY; EX VIVO STUDY; GENE EXPRESSION; GLYCOSAMINOGLYCAN METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; JOINT SWELLING; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NANOENCAPSULATION; NONHUMAN; OSTEOARTHRITIS; PAW EDEMA; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SCANNING ELECTRON MICROSCOPY; TISSUE REGENERATION; ANALOGS AND DERIVATIVES; ANIMAL; ARTHRITIS, EXPERIMENTAL; CELL LINE; CHEMISTRY; COMMIPHORA; CYTOLOGY; DBA MOUSE; DRUG EFFECTS; IMMUNOLOGY; MALE; PATHOLOGY;

ALGINATES; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CALCIUM PHOSPHATES; CELL LINE; CHITOSAN; CHONDROCYTES; COMMIPHORA; DRUG CARRIERS; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; INTERLEUKIN-1BETA; MALE; MICE, INBRED DBA; NANOSTRUCTURES; PLANT EXTRACTS; PLANT GUMS;

EID: 84903794555     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.13.219     Document Type: Article

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