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Volumn 9, Issue 10-12, 2012, Pages 942-960

Novel nanoplatform for oral delivery of anti-cancer biomacromolecules

Author keywords

Alginate; Anti cancer proteins; Ceramic nano cores; Chitosan; Endocytosis and transcytosis; Lactoferrin; Nano carriers; Oral drug delivery

Indexed keywords

ALGINATE; CELL CULTURE; CERAMIC MATERIALS; CHITOSAN; CONTROLLED DRUG DELIVERY; DIGESTIVE SYSTEM; DISEASES; MAMMALS; MOLECULAR BIOLOGY; NANOPARTICLES; NUCLEIC ACIDS; PROTEINS;

EID: 84867289186     PISSN: 14757435     EISSN: None     Source Type: Journal    
DOI: 10.1504/IJNT.2012.049457     Document Type: Article
Times cited : (9)

References (52)
  • 1
    • 0027402592 scopus 로고
    • Molecular aspects of tumor cell invasion and metastasis
    • Aznavoorian, S., Murphy, A.N., Stetler-Stevenson, W.G. and Liotta, L.A. (1993) 'Molecular aspects of tumor cell invasion and metastasis', Cancer, Vol. 71, No. 4, pp.1368-1383.
    • (1993) Cancer , vol.71 , Issue.4 , pp. 1368-1383
    • Aznavoorian, S.1    Murphy, A.N.2    Stetler-Stevenson, W.G.3    Liotta, L.A.4
  • 2
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman, J. (1995) 'Angiogenesis in cancer, vascular, rheumatoid and other disease', Nat. Med., Vol. 1, No. 1, pp.27-31.
    • (1995) Nat. Med. , vol.1 , Issue.1 , pp. 27-31
    • Folkman, J.1
  • 3
    • 0037805549 scopus 로고    scopus 로고
    • Basement membranes: Structure, assembly and role in tumour angiogenesis
    • Kalluri, R. (2003) 'Basement membranes: structure, assembly and role in tumour angiogenesis', Nat. Rev. Cancer, Vol. 3, No. 6, pp.422-433.
    • (2003) Nat. Rev. Cancer , vol.3 , Issue.6 , pp. 422-433
    • Kalluri, R.1
  • 4
    • 0036488496 scopus 로고    scopus 로고
    • Specialization of tumour vasculature
    • Ruoslahti, E. (2002) 'Specialization of tumour vasculature', Nat. Rev. Cancer, Vol. 2, No. 2, pp.83-90.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.2 , pp. 83-90
    • Ruoslahti, E.1
  • 5
    • 72449150594 scopus 로고    scopus 로고
    • Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice
    • Jiang, H., Tao, W., Zhang, M., Pan, S., Kanwar, J.R. and Sun, X. (2010) 'Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice', Cancer Invest., Vol. 28, No. 1, pp.74-84.
    • (2010) Cancer Invest. , vol.28 , Issue.1 , pp. 74-84
    • Jiang, H.1    Tao, W.2    Zhang, M.3    Pan, S.4    Kanwar, J.R.5    Sun, X.6
  • 6
    • 70349384629 scopus 로고    scopus 로고
    • Recent advances on the roles of NO in cancer and chronic inflammatory disorders
    • Kanwar, J.R., Kanwar, R.K., Burrow, H. and Baratchi, S. (2009) 'Recent advances on the roles of NO in cancer and chronic inflammatory disorders', Curr. Med. Chem., Vol. 16, No. 19, pp.2373-2394.
    • (2009) Curr. Med. Chem. , vol.16 , Issue.19 , pp. 2373-2394
    • Kanwar, J.R.1    Kanwar, R.K.2    Burrow, H.3    Baratchi, S.4
  • 7
    • 33644855144 scopus 로고    scopus 로고
    • Arsenic trioxide synergizes with B7H3-mediated immunotherapy to eradicate hepatocellular carcinomas
    • Luo, L., Qiao, H., Meng, F., Dong, X., Zhou, B., Jiang, H., Kanwar, J.R., Krissansen, G.W. and Sun, X. (2006) 'Arsenic trioxide synergizes with B7H3-mediated immunotherapy to eradicate hepatocellular carcinomas', Int. J. Cancer, Vol. 118, No. 7, pp.1823-1830.
    • (2006) Int. J. Cancer , vol.118 , Issue.7 , pp. 1823-1830
    • Luo, L.1    Qiao, H.2    Meng, F.3    Dong, X.4    Zhou, B.5    Jiang, H.6    Kanwar, J.R.7    Krissansen, G.W.8    Sun, X.9
  • 8
    • 10844242277 scopus 로고    scopus 로고
    • Intramuscular delivery of antiangiogenic genes suppresses secondary metastases after removal of primary tumors
    • Sun, X., Qiao, H., Jiang, H., Zhi, X., Liu, F., Wang, J., Liu, M., Dong, D., Kanwar, J.R., Xu, R. and Krissansen, G.W. (2004) 'Intramuscular delivery of antiangiogenic genes suppresses secondary metastases after removal of primary tumors', Cancer Gene Ther., Vol. 12, No. 1, pp.35-45.
    • (2004) Cancer Gene Ther. , vol.12 , Issue.1 , pp. 35-45
    • Sun, X.1    Qiao, H.2    Jiang, H.3    Zhi, X.4    Liu, F.5    Wang, J.6    Liu, M.7    Dong, D.8    Kanwar, J.R.9    Xu, R.10    Krissansen, G.W.11
  • 9
    • 77953509436 scopus 로고    scopus 로고
    • Recent advances in anti-survivin treatments for cancer
    • in Press
    • Kanwar, R.K., Cheung, C.H.A., Chang, J-Y. and Kanwar, J.R. (2010) 'Recent advances in anti-survivin treatments for cancer', Curr. Med. Chem., Vol. 17, No. 15 (in Press).
    • (2010) Curr. Med. Chem. , vol.17 , Issue.15
    • Kanwar, R.K.1    Cheung, C.H.A.2    Chang, J.-Y.3    Kanwar, J.R.4
  • 11
    • 0029985206 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of O-(chloroacetyl-carbamoyl) fumagillol (TNP-470, AGM-1470) in rhesus monkeys
    • Cretton-Scott, E., Placidi, L., McClure, H., Anderson, D.C. and Sommadossi, J-P. (1996) 'Pharmacokinetics and metabolism of O-(chloroacetyl- carbamoyl) fumagillol (TNP-470, AGM-1470) in rhesus monkeys', Cancer Chemother. Pharmacol., Vol. 38, No. 2, pp.117-122.
    • (1996) Cancer Chemother. Pharmacol. , vol.38 , Issue.2 , pp. 117-122
    • Cretton-Scott, E.1    Placidi, L.2    McClure, H.3    Anderson, D.C.4    Sommadossi, J.-P.5
  • 13
    • 33645469800 scopus 로고    scopus 로고
    • Epidermal growth factor-conjugated poly(ethylene glycol)-block- poly(Î-valerolactone) copolymer micelles for targeted delivery of chemotherapeutics
    • Zeng, F., Lee, H. and Allen, C. (2006) 'Epidermal growth factor-conjugated poly(ethylene glycol)-block- poly(Î-valerolactone) copolymer micelles for targeted delivery of chemotherapeutics', Bioconjugate Chem., Vol. 17, No. 2, pp.399-409.
    • (2006) Bioconjugate Chem. , vol.17 , Issue.2 , pp. 399-409
    • Zeng, F.1    Lee, H.2    Allen, C.3
  • 14
    • 39749105878 scopus 로고    scopus 로고
    • Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy
    • Kim, J.H., Kim, Y.S., Park, K., Kang, E., Lee, S., Nam, H.Y., Kim, K., Park, J.H., Chi, D.Y., Park, R.W., Kim, I.S., Choi, K. and Chan Kwon, I. (2008) 'Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy', Biomaterials, Vol. 29, No. 12, pp.1920-1930.
    • (2008) Biomaterials , vol.29 , Issue.12 , pp. 1920-1930
    • Kim, J.H.1    Kim, Y.S.2    Park, K.3    Kang, E.4    Lee, S.5    Nam, H.Y.6    Kim, K.7    Park, J.H.8    Chi, D.Y.9    Park, R.W.10    Kim, I.S.11    Choi, K.12    Chan Kwon, I.13
  • 15
    • 34147126384 scopus 로고    scopus 로고
    • Recent advances in protein and peptide drug delivery systems
    • Kumar Malik, D., Baboota, S., Ahuja, A., Hasan, S. and Ali, J. (2007) 'Recent advances in protein and peptide drug delivery systems', Curr. Drug Delivery, Vol. 4, No. 2, pp.141-151.
    • (2007) Curr. Drug Delivery , vol.4 , Issue.2 , pp. 141-151
    • Kumar Malik, D.1    Baboota, S.2    Ahuja, A.3    Hasan, S.4    Ali, J.5
  • 16
    • 45849138160 scopus 로고    scopus 로고
    • Target-specific drug release to the colon
    • Jain, S.K. and Jain, A. (2008) 'Target-specific drug release to the colon', Expert Opin. Drug Delivery, Vol. 5, No. 5, pp.483-498.
    • (2008) Expert Opin. Drug Delivery , vol.5 , Issue.5 , pp. 483-498
    • Jain, S.K.1    Jain, A.2
  • 17
    • 0025781658 scopus 로고
    • Peptide and protein drugs: I. Therapeutic applications, absorption and parenteral administration
    • Zhou, X.H. and Li Wan Po, A. (1991) 'Peptide and protein drugs: I. Therapeutic applications, absorption and parenteral administration', Int. J. Pharm., Vol. 75, Nos. 2-3, pp.97-115.
    • (1991) Int. J. Pharm. , vol.75 , Issue.2-3 , pp. 97-115
    • Zhou, X.H.1    Li Wan Po, A.2
  • 19
    • 34248360301 scopus 로고    scopus 로고
    • Nanomedicine: Nanocarriers shape up for long life
    • Nishiyama, N. (2007) 'Nanomedicine: nanocarriers shape up for long life', Nat. Nanotechnol., Vol. 2, No. 4, pp.203-204.
    • (2007) Nat. Nanotechnol. , vol.2 , Issue.4 , pp. 203-204
    • Nishiyama, N.1
  • 21
    • 33747840618 scopus 로고    scopus 로고
    • Polymer conjugates as anticancer nanomedicines
    • Duncan, R. (2006) 'Polymer conjugates as anticancer nanomedicines', Nat. Rev. Cancer, Vol. 6, No. 9, pp.688-701.
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.9 , pp. 688-701
    • Duncan, R.1
  • 25
    • 70350761693 scopus 로고    scopus 로고
    • Recent advances in nanoneurology for drug delivery to the brain
    • Kanwar, J.R., Mahidhara, G. and Kanwar, R.K. (2009) 'Recent advances in nanoneurology for drug delivery to the brain', Curr. Nanosci., Vol. 5, No. 4, pp.1573-4137.
    • (2009) Curr. Nanosci. , vol.5 , Issue.4 , pp. 1573-4137
    • Kanwar, J.R.1    Mahidhara, G.2    Kanwar, R.K.3
  • 26
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura, Y. and Maeda, H. (1986) 'A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs', Cancer Res., Vol. 46, No. 12, Part 1, pp.6387-6392.
    • (1986) Cancer Res. , vol.46 , Issue.12 PART 1 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 27
    • 0242360811 scopus 로고    scopus 로고
    • Assessment of normal and tumor tissue uptake of MAG-CPT, a polymer-bound prodrug of camptothecin, in patients undergoing elective surgery for colorectal carcinoma
    • Sarapa, N., Britto, M., Speed, W., Jannuzzo, M., Breda, M., James, C., Porro, M., Rocchetti, M., Wanders, A., Mahteme, H. and Nygren, P. (2003) 'Assessment of normal and tumor tissue uptake of MAG-CPT, a polymer-bound prodrug of camptothecin, in patients undergoing elective surgery for colorectal carcinoma', Cancer Chemother. Pharmacol., Vol. 52, No. 5, pp.424-430.
    • (2003) Cancer Chemother. Pharmacol. , vol.52 , Issue.5 , pp. 424-430
    • Sarapa, N.1    Britto, M.2    Speed, W.3    Jannuzzo, M.4    Breda, M.5    James, C.6    Porro, M.7    Rocchetti, M.8    Wanders, A.9    Mahteme, H.10    Nygren, P.11
  • 28
    • 42749096481 scopus 로고    scopus 로고
    • Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles
    • Hwang, H-Y., Kim, I-S., Kwon, I.C. and Kim, Y-H. (2008) 'Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles', J. Controlled Release, Vol. 128, No. 1, pp.23-31.
    • (2008) J. Controlled Release , vol.128 , Issue.1 , pp. 23-31
    • Hwang, H.-Y.1    Kim, I.-S.2    Kwon, I.C.3    Kim, Y.-H.4
  • 30
    • 33750046646 scopus 로고    scopus 로고
    • Chitosan surface-modified hydroxycamptothecin loaded nanoparticles with enhanced transport across Caco-2 cell monolayer
    • Zhang, L., Sun, M., Guo, R., Jiang, Z., Liu, Y., Jiang, X. and Yang, C. (2006) 'Chitosan surface-modified hydroxycamptothecin loaded nanoparticles with enhanced transport across Caco-2 cell monolayer', J. Nanosci. Nanotechnol., Vol. 6, No. 10, pp.2912-2920.
    • (2006) J. Nanosci. Nanotechnol. , vol.6 , Issue.10 , pp. 2912-2920
    • Zhang, L.1    Sun, M.2    Guo, R.3    Jiang, Z.4    Liu, Y.5    Jiang, X.6    Yang, C.7
  • 32
    • 44049092672 scopus 로고    scopus 로고
    • Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect
    • Wang, A. and Li, S. (2008) 'Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect', BMC Biotech., Vol. 8, No. 1, p.46.
    • (2008) BMC Biotech. , vol.8 , Issue.1 , pp. 46
    • Wang, A.1    Li, S.2
  • 33
    • 58149215702 scopus 로고    scopus 로고
    • Chitosan/siRNA Nanoparticle-mediated TNF-[alpha] knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model
    • Howard, K.A., Paludan, S.R., Behlke, M.A., Besenbacher, F., Deleuran, B. and Kjems, J. (2008) 'Chitosan/siRNA Nanoparticle-mediated TNF-[alpha] knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model', Mol. Ther., Vol. 17, No. 1, pp.162-168.
    • (2008) Mol. Ther. , vol.17 , Issue.1 , pp. 162-168
    • Howard, K.A.1    Paludan, S.R.2    Behlke, M.A.3    Besenbacher, F.4    Deleuran, B.5    Kjems, J.6
  • 34
    • 58849095012 scopus 로고    scopus 로고
    • Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells
    • Yadav, S., van Vlerken, L., Little, S. and Amiji, M. (2009) 'Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells', Cancer Chemother. Pharmacol., Vol. 63, No. 4, pp.711-722.
    • (2009) Cancer Chemother. Pharmacol. , vol.63 , Issue.4 , pp. 711-722
    • Yadav, S.1    Van Vlerken, L.2    Little, S.3    Amiji, M.4
  • 35
    • 46749107462 scopus 로고    scopus 로고
    • In vitro and in vivo investigation on PLA-TPGS nanoparticles for controlled and sustained small molecule chemotherapy
    • Zhang, Z., Lee, S., Gan, C. and Feng, S-S. (2008) 'In vitro and in vivo investigation on PLA-TPGS nanoparticles for controlled and sustained small molecule chemotherapy', Pharm. Res., Vol. 25, No. 8, pp.1925-1935.
    • (2008) Pharm. Res. , vol.25 , Issue.8 , pp. 1925-1935
    • Zhang, Z.1    Lee, S.2    Gan, C.3    Feng, S.-S.4
  • 36
    • 67349198099 scopus 로고    scopus 로고
    • Poly (lactide)-vitamin e derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel
    • Feng, S-S., Mei, L., Anitha, P., Gan, C.W. and Zhou, W. (2009) 'Poly (lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel', Biomaterials, Vol. 30, No. 19, pp.3297-3306.
    • (2009) Biomaterials , vol.30 , Issue.19 , pp. 3297-3306
    • Feng, S.-S.1    Mei, L.2    Anitha, P.3    Gan, C.W.4    Zhou, W.5
  • 37
    • 39849104152 scopus 로고    scopus 로고
    • Development and in vitro evaluation of alginate gel encapsulated, chitosan-coated ceramic nanocores for oral delivery of enzyme
    • Rawat, M., Singh, D., Saraf, S. and Saraf, S. (2008) 'Development and in vitro evaluation of alginate gel encapsulated, chitosan-coated ceramic nanocores for oral delivery of enzyme', Drug Dev. Ind. Pharm., Vol. 34, No. 2, pp.181-188.
    • (2008) Drug Dev. Ind. Pharm. , vol.34 , Issue.2 , pp. 181-188
    • Rawat, M.1    Singh, D.2    Saraf, S.3    Saraf, S.4
  • 38
    • 50949132083 scopus 로고    scopus 로고
    • Processing conditions for the formation of spider silk microspheres
    • Lammel, A., Schwab, M., Slotta, U., Winter, G. and Scheibel, T. (2008) 'Processing conditions for the formation of spider silk microspheres', ChemSusChem., Vol. 1, No. 5, pp.413-416.
    • (2008) ChemSusChem. , vol.1 , Issue.5 , pp. 413-416
    • Lammel, A.1    Schwab, M.2    Slotta, U.3    Winter, G.4    Scheibel, T.5
  • 39
    • 47149110216 scopus 로고    scopus 로고
    • An engineered spider silk protein forms Microspheres13
    • Slotta, U.K., Rammensee, S., Gorb, S. and Scheibel, T. (2008) 'An engineered spider silk protein forms Microspheres13', Angew. Chem. Int. Ed., Vol. 47, No. 24, pp.4592-4594.
    • (2008) Angew. Chem. Int. Ed. , vol.47 , Issue.24 , pp. 4592-4594
    • Slotta, U.K.1    Rammensee, S.2    Gorb, S.3    Scheibel, T.4
  • 40
    • 70449840145 scopus 로고    scopus 로고
    • Recent advances of metal binding protein lactoferrin as an anti- microbial agent
    • Gupta, I., Sehgal, R., Kanwar, R.K., Sehgal, A. and Kanwar, J.R. (2009) 'Recent advances of metal binding protein lactoferrin as an anti- microbial agent', Curr. Bioact. Compd., Vol. 5, No. 3, pp.226-233.
    • (2009) Curr. Bioact. Compd. , vol.5 , Issue.3 , pp. 226-233
    • Gupta, I.1    Sehgal, R.2    Kanwar, R.K.3    Sehgal, A.4    Kanwar, J.R.5
  • 42
    • 65249142207 scopus 로고    scopus 로고
    • Gut health immunomodulatory and anti-inflammatory functions of gut enzyme digested high protein micro-nutrient dietary supplement-Enprocal
    • Kanwar, J. and Kanwar, R. (2009) 'Gut health immunomodulatory and anti-inflammatory functions of gut enzyme digested high protein micro-nutrient dietary supplement-Enprocal', BMC Immunol., Vol. 10, No. 1, p.7.
    • (2009) BMC Immunol. , vol.10 , Issue.1 , pp. 7
    • Kanwar, J.1    Kanwar, R.2
  • 44
    • 0034113115 scopus 로고    scopus 로고
    • Self-assembled carbohydrate-stabilized ceramic nanoparticles for the parenteral delivery of insulin
    • Cherian, A.K., Rana, A.C. and Jain, S.K. (2000) 'Self-assembled carbohydrate-stabilized ceramic nanoparticles for the parenteral delivery of insulin', Drug Develop. Ind. Pharm., Vol. 26, No. 4, pp.459-463.
    • (2000) Drug Develop. Ind. Pharm. , vol.26 , Issue.4 , pp. 459-463
    • Cherian, A.K.1    Rana, A.C.2    Jain, S.K.3
  • 45
    • 38049112372 scopus 로고    scopus 로고
    • PH-controlled construction of chitosan/alginate multilayer film: Characterization and application for antibody immobilization
    • Yuan, W., Dong, H., Li, C.M., Cui, X., Yu, L., Lu, Z. and Zhou, Q. (2007) 'pH-controlled construction of chitosan/alginate multilayer film: characterization and application for antibody immobilization', Langmuir, Vol. 23, No. 26, pp.13046-13052.
    • (2007) Langmuir , vol.23 , Issue.26 , pp. 13046-13052
    • Yuan, W.1    Dong, H.2    Li, C.M.3    Cui, X.4    Yu, L.5    Lu, Z.6    Zhou, Q.7
  • 46
    • 0030940283 scopus 로고    scopus 로고
    • [alpha]v Integrins as receptors for tumor targeting by circulating ligands
    • Pasqualini, R., Koivunen, E. and Ruoslahti, E. (1997) '[alpha]v Integrins as receptors for tumor targeting by circulating ligands', Nat. Biotechol., Vol. 15, No. 6, pp.542-546.
    • (1997) Nat. Biotechol. , vol.15 , Issue.6 , pp. 542-546
    • Pasqualini, R.1    Koivunen, E.2    Ruoslahti, E.3
  • 47
    • 0035904376 scopus 로고    scopus 로고
    • Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy
    • Kanwar, J.R., Shen, W.P., Kanwar, R.K., Berg, R.W. and Krissansen, G.W. (2001) 'Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy', J. Natl. Cancer Inst., Vol. 93, No. 20, pp.1541-1552.
    • (2001) J. Natl. Cancer Inst. , vol.93 , Issue.20 , pp. 1541-1552
    • Kanwar, J.R.1    Shen, W.P.2    Kanwar, R.K.3    Berg, R.W.4    Krissansen, G.W.5
  • 48
    • 70350234507 scopus 로고    scopus 로고
    • Survivin: A new target for anti-cancer therapy
    • Ryan, B.M., O'Donovan, N. and Duffy, M.J. (2009) 'Survivin: a new target for anti-cancer therapy', Cancer Treatment Reviews, Vol. 35, No. 7, pp.553-562.
    • (2009) Cancer Treatment Reviews , vol.35 , Issue.7 , pp. 553-562
    • Ryan, B.M.1    O'donovan, N.2    Duffy, M.J.3
  • 51
    • 35248825099 scopus 로고    scopus 로고
    • Nanotechnology for antiangiogenic cancer therapy
    • Kobayashi, H. and Lin, P.C. (2006) 'Nanotechnology for antiangiogenic cancer therapy', Nanomed., Vol. 1, No. 1, pp.17-22.
    • (2006) Nanomed. , vol.1 , Issue.1 , pp. 17-22
    • Kobayashi, H.1    Lin, P.C.2
  • 52
    • 0032403533 scopus 로고    scopus 로고
    • Oral particulate delivery: Status and future trends
    • Chen, H. and Langer, R. (1998) 'Oral particulate delivery: status and future trends', Adv. Drug Delivery Rev., Vol. 34, Nos. 2-3, pp.339-350.
    • (1998) Adv. Drug Delivery Rev. , vol.34 , Issue.2-3 , pp. 339-350
    • Chen, H.1    Langer, R.2


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