-
1
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362:59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
-
2
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase
-
Deng H.X., Hentati A., Tainer J.A., Iqbal Z., Cayabyab A., Hung W.Y., et al. Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science 1993, 261:1047-1051.
-
(1993)
Science
, vol.261
, pp. 1047-1051
-
-
Deng, H.X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.Y.6
-
3
-
-
33751003518
-
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target
-
Barber S.C., Mead R.J., Shaw P.J. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim Biophys Acta 2006, 1762:1051-1067.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 1051-1067
-
-
Barber, S.C.1
Mead, R.J.2
Shaw, P.J.3
-
4
-
-
0028888945
-
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
-
Ripps M.E., Huntley G.W., Hof P.R., Morrison J.H., Gordon J.W. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 1995, 92:689-693.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 689-693
-
-
Ripps, M.E.1
Huntley, G.W.2
Hof, P.R.3
Morrison, J.H.4
Gordon, J.W.5
-
5
-
-
77956978329
-
Motor neuron-immune interactions: the vicious circle of ALS
-
Barbeito A.G., Mesci P., Boillee S. Motor neuron-immune interactions: the vicious circle of ALS. J Neural Transm 2010, 117:981-1000.
-
(2010)
J Neural Transm
, vol.117
, pp. 981-1000
-
-
Barbeito, A.G.1
Mesci, P.2
Boillee, S.3
-
6
-
-
3343020674
-
Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model
-
Dupuis L., Oudart H., Rene F., Gonzalez de Aguilar J.L., Loeffler J.P. Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model. Proc Natl Acad Sci U S A 2004, 101:11159-11164.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 11159-11164
-
-
Dupuis, L.1
Oudart, H.2
Rene, F.3
Gonzalez de Aguilar, J.L.4
Loeffler, J.P.5
-
7
-
-
34548145662
-
Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis
-
Fergani A., Oudart H., Gonzalez De Aguilar J.L., Fricker B., Rene F., Hocquette J.F., et al. Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis. J Lipid Res 2007, 48:1571-1580.
-
(2007)
J Lipid Res
, vol.48
, pp. 1571-1580
-
-
Fergani, A.1
Oudart, H.2
Gonzalez De Aguilar, J.L.3
Fricker, B.4
Rene, F.5
Hocquette, J.F.6
-
9
-
-
0033606410
-
No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice
-
Pedersen W.A., Mattson M.P. No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice. Brain Res 1999, 833:117-120.
-
(1999)
Brain Res
, vol.833
, pp. 117-120
-
-
Pedersen, W.A.1
Mattson, M.P.2
-
10
-
-
54849404282
-
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity
-
Dobrowolny G., Aucello M., Rizzuto E., Beccafico S., Mammucari C., Boncompagni S., et al. Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab 2008, 8:425-436.
-
(2008)
Cell Metab
, vol.8
, pp. 425-436
-
-
Dobrowolny, G.1
Aucello, M.2
Rizzuto, E.3
Beccafico, S.4
Mammucari, C.5
Boncompagni, S.6
-
11
-
-
0036120847
-
Mediterranean diet and stroke: objectives and design of the SUN project. Seguimiento Universidad de Navarra
-
Martinez-Gonzalez M.A., Sanchez-Villegas A., De Irala J., Marti A., Martinez J.A. Mediterranean diet and stroke: objectives and design of the SUN project. Seguimiento Universidad de Navarra. Nutr Neurosci 2002, 5:65-73.
-
(2002)
Nutr Neurosci
, vol.5
, pp. 65-73
-
-
Martinez-Gonzalez, M.A.1
Sanchez-Villegas, A.2
De Irala, J.3
Marti, A.4
Martinez, J.A.5
-
12
-
-
68849119553
-
Physical activity, diet, and risk of Alzheimer disease
-
Scarmeas N., Luchsinger J.A., Schupf N., Brickman A.M., Cosentino S., Tang M.X., et al. Physical activity, diet, and risk of Alzheimer disease. JAMA 2009, 302:627-637.
-
(2009)
JAMA
, vol.302
, pp. 627-637
-
-
Scarmeas, N.1
Luchsinger, J.A.2
Schupf, N.3
Brickman, A.M.4
Cosentino, S.5
Tang, M.X.6
-
13
-
-
84875787136
-
Primary prevention of cardiovascular disease with a Mediterranean diet
-
Estruch R., Ros E., Salas-Salvado J., Covas M.I., Corella D., Aros F., et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med 2013, 368:1279-1290.
-
(2013)
N Engl J Med
, vol.368
, pp. 1279-1290
-
-
Estruch, R.1
Ros, E.2
Salas-Salvado, J.3
Covas, M.I.4
Corella, D.5
Aros, F.6
-
14
-
-
77950952757
-
Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaen and Cordoba (Spain) 2008
-
Lopez-Miranda J., Perez-Jimenez F., Ros E., De Caterina R., Badimon L., Covas M.I., et al. Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaen and Cordoba (Spain) 2008. Nutr Metab Cardiovasc Dis 2010, 20:284-294.
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, pp. 284-294
-
-
Lopez-Miranda, J.1
Perez-Jimenez, F.2
Ros, E.3
De Caterina, R.4
Badimon, L.5
Covas, M.I.6
-
15
-
-
63849300346
-
Knowledge of the biological actions of extra virgin olive oil gained from mice lacking apolipoprotein E
-
Guillen N., Acin S., Navarro M.A., Surra J.C., Arnal C., Lou-Bonafonte J.M., et al. Knowledge of the biological actions of extra virgin olive oil gained from mice lacking apolipoprotein E. Rev Esp Cardiol 2009, 62:294-304.
-
(2009)
Rev Esp Cardiol
, vol.62
, pp. 294-304
-
-
Guillen, N.1
Acin, S.2
Navarro, M.A.3
Surra, J.C.4
Arnal, C.5
Lou-Bonafonte, J.M.6
-
16
-
-
0032857364
-
Low-cholesterol and high-fat diets reduce atherosclerotic lesion development in ApoE-knockout mice
-
Calleja L., Paris M.A., Paul A., Vilella E., Joven J., Jimenez A., et al. Low-cholesterol and high-fat diets reduce atherosclerotic lesion development in ApoE-knockout mice. Arterioscler Thromb Vasc Biol 1999, 19:2368-2375.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 2368-2375
-
-
Calleja, L.1
Paris, M.A.2
Paul, A.3
Vilella, E.4
Joven, J.5
Jimenez, A.6
-
17
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillee S., Yamanaka K., Lobsiger C.S., Copeland N.G., Jenkins N.A., Kassiotis G., et al. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006, 312:1389-1392.
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillee, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
-
18
-
-
20444491899
-
Immune-regulation of the apolipoprotein A-I/C-III/A-IV gene cluster in experimental inflammation
-
Navarro M.A., Carpintero R., Acin S., Arbones-Mainar J.M., Calleja L., Carnicer R., et al. Immune-regulation of the apolipoprotein A-I/C-III/A-IV gene cluster in experimental inflammation. Cytokine 2005, 31:52-63.
-
(2005)
Cytokine
, vol.31
, pp. 52-63
-
-
Navarro, M.A.1
Carpintero, R.2
Acin, S.3
Arbones-Mainar, J.M.4
Calleja, L.5
Carnicer, R.6
-
19
-
-
84873840146
-
Postprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oil
-
Martinez-Beamonte R., Navarro M.A., Acin S., Guillen N., Barranquero C., Arnal C., et al. Postprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oil. PLoS ONE 2013, 8:e55231.
-
(2013)
PLoS ONE
, vol.8
-
-
Martinez-Beamonte, R.1
Navarro, M.A.2
Acin, S.3
Guillen, N.4
Barranquero, C.5
Arnal, C.6
-
20
-
-
0034891279
-
A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids
-
Navab M., Hama S.Y., Hough G.P., Subbanagounder G., Reddy S.T., Fogelman A.M. A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids. J Lipid Res 2001, 42:1308-1317.
-
(2001)
J Lipid Res
, vol.42
, pp. 1308-1317
-
-
Navab, M.1
Hama, S.Y.2
Hough, G.P.3
Subbanagounder, G.4
Reddy, S.T.5
Fogelman, A.M.6
-
21
-
-
84873042720
-
In comparison with palm oil, dietary nut supplementation delays the progression of atherosclerotic lesions in female apoE-deficient mice
-
Surra J.C., Barranquero C., Torcal M.P., Orman I., Segovia J.C., Guillen N., et al. In comparison with palm oil, dietary nut supplementation delays the progression of atherosclerotic lesions in female apoE-deficient mice. Br J Nutr 2013, 109:202-209.
-
(2013)
Br J Nutr
, vol.109
, pp. 202-209
-
-
Surra, J.C.1
Barranquero, C.2
Torcal, M.P.3
Orman, I.4
Segovia, J.C.5
Guillen, N.6
-
22
-
-
84857839750
-
Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice
-
Calvo A.C., Manzano R., Atencia-Cibreiro G., Olivan S., Munoz M.J., Zaragoza P., et al. Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice. PLoS ONE 2012, 7:e32632.
-
(2012)
PLoS ONE
, vol.7
-
-
Calvo, A.C.1
Manzano, R.2
Atencia-Cibreiro, G.3
Olivan, S.4
Munoz, M.J.5
Zaragoza, P.6
-
23
-
-
79958810150
-
Altered expression of myogenic regulatory factors in the mouse model of amyotrophic lateral sclerosis
-
Manzano R., Toivonen J.M., Olivan S., Calvo A.C., Moreno-Igoa M., Munoz M.J., et al. Altered expression of myogenic regulatory factors in the mouse model of amyotrophic lateral sclerosis. Neurodegener Dis 2011, 8:386-396.
-
(2011)
Neurodegener Dis
, vol.8
, pp. 386-396
-
-
Manzano, R.1
Toivonen, J.M.2
Olivan, S.3
Calvo, A.C.4
Moreno-Igoa, M.5
Munoz, M.J.6
-
24
-
-
77956227934
-
Cysteinemia, rather than homocysteinemia, is associated with plasma apolipoprotein A-I levels in hyperhomocysteinemia: lipid metabolism in cystathionine beta-synthase deficiency
-
Nuno-Ayala M., Guillen N., Navarro M.A., Lou-Bonafonte J.M., Arnal C., Gascon S., et al. Cysteinemia, rather than homocysteinemia, is associated with plasma apolipoprotein A-I levels in hyperhomocysteinemia: lipid metabolism in cystathionine beta-synthase deficiency. Atherosclerosis 2010, 212:268-273.
-
(2010)
Atherosclerosis
, vol.212
, pp. 268-273
-
-
Nuno-Ayala, M.1
Guillen, N.2
Navarro, M.A.3
Lou-Bonafonte, J.M.4
Arnal, C.5
Gascon, S.6
-
25
-
-
84870394203
-
Proteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic steatosis
-
Ramirez-Torres A., Barcelo-Batllori S., Martinez-Beamonte R., Navarro M.A., Surra J.C., Arnal C., et al. Proteomics and gene expression analyses of squalene-supplemented mice identify microsomal thioredoxin domain-containing protein 5 changes associated with hepatic steatosis. J Proteomics 2012, 77:27-39.
-
(2012)
J Proteomics
, vol.77
, pp. 27-39
-
-
Ramirez-Torres, A.1
Barcelo-Batllori, S.2
Martinez-Beamonte, R.3
Navarro, M.A.4
Surra, J.C.5
Arnal, C.6
-
26
-
-
45549102437
-
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells
-
Coll T., Eyre E., Rodriguez-Calvo R., Palomer X., Sanchez R.M., Merlos M., et al. Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells. J Biol Chem 2008, 283:11107-11116.
-
(2008)
J Biol Chem
, vol.283
, pp. 11107-11116
-
-
Coll, T.1
Eyre, E.2
Rodriguez-Calvo, R.3
Palomer, X.4
Sanchez, R.M.5
Merlos, M.6
-
27
-
-
84877770648
-
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism
-
Salvado L., Coll T., Gomez-Foix A.M., Salmeron E., Barroso E., Palomer X., et al. Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Diabetologia 2013, 56:1372-1382.
-
(2013)
Diabetologia
, vol.56
, pp. 1372-1382
-
-
Salvado, L.1
Coll, T.2
Gomez-Foix, A.M.3
Salmeron, E.4
Barroso, E.5
Palomer, X.6
-
28
-
-
84855966721
-
Role of endoplasmic reticulum stress in metabolic disease and other disorders
-
Ozcan L., Tabas I. Role of endoplasmic reticulum stress in metabolic disease and other disorders. Annu Rev Med 2012, 63:317-328.
-
(2012)
Annu Rev Med
, vol.63
, pp. 317-328
-
-
Ozcan, L.1
Tabas, I.2
-
29
-
-
84885382830
-
SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency
-
Homma K., Fujisawa T., Tsuburaya N., Yamaguchi N., Kadowaki H., Takeda K., et al. SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency. Mol Cell 2013, 52:75-86.
-
(2013)
Mol Cell
, vol.52
, pp. 75-86
-
-
Homma, K.1
Fujisawa, T.2
Tsuburaya, N.3
Yamaguchi, N.4
Kadowaki, H.5
Takeda, K.6
-
30
-
-
84881587124
-
PGC-1alpha is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis
-
Eschbach J., Schwalenstocker B., Soyal S.M., Bayer H., Wiesner D., Akimoto C., et al. PGC-1alpha is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis. Hum Mol Genet 2013, 22:3477-3484.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 3477-3484
-
-
Eschbach, J.1
Schwalenstocker, B.2
Soyal, S.M.3
Bayer, H.4
Wiesner, D.5
Akimoto, C.6
-
31
-
-
84874566621
-
Mitochondrial network genes in the skeletal muscle of amyotrophic lateral sclerosis patients
-
Bernardini C., Censi F., Lattanzi W., Barba M., Calcagnini G., Giuliani A., et al. Mitochondrial network genes in the skeletal muscle of amyotrophic lateral sclerosis patients. PLoS ONE 2013, 8:e57739.
-
(2013)
PLoS ONE
, vol.8
-
-
Bernardini, C.1
Censi, F.2
Lattanzi, W.3
Barba, M.4
Calcagnini, G.5
Giuliani, A.6
-
32
-
-
58449118927
-
Amyotrophic lateral sclerosis: role of energy deficiency in neuromuscular junction dismantlement
-
Dupuis L., Loeffler J.P. Amyotrophic lateral sclerosis: role of energy deficiency in neuromuscular junction dismantlement. Med Sci (Paris) 2008, 24:1077-1082.
-
(2008)
Med Sci (Paris)
, vol.24
, pp. 1077-1082
-
-
Dupuis, L.1
Loeffler, J.P.2
-
33
-
-
84855578683
-
State of the art and the dark side of amyotrophic lateral sclerosis
-
Musaro A. State of the art and the dark side of amyotrophic lateral sclerosis. World J Biol Chem 2010, 1:62-68.
-
(2010)
World J Biol Chem
, vol.1
, pp. 62-68
-
-
Musaro, A.1
-
34
-
-
84902314640
-
Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial
-
Feb 27 [pii: S0140-6736(14)60222-1]
-
Wills A.M., Hubbard J., Macklin E.A., Glass J., Tandan R., Simpson E.P., et al. Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet 2014, Feb 27 [pii: S0140-6736(14)60222-1].
-
(2014)
Lancet
-
-
Wills, A.M.1
Hubbard, J.2
Macklin, E.A.3
Glass, J.4
Tandan, R.5
Simpson, E.P.6
-
35
-
-
84898959061
-
Hydroxytyrosol attenuates tunicamycin-induced endoplasmic reticulum stress in human hepatocarcinoma cells
-
Giordano E., Davalos A., Nicod N., Visioli F. Hydroxytyrosol attenuates tunicamycin-induced endoplasmic reticulum stress in human hepatocarcinoma cells. Mol Nutr Food Res 2014, 58:954-962.
-
(2014)
Mol Nutr Food Res
, vol.58
, pp. 954-962
-
-
Giordano, E.1
Davalos, A.2
Nicod, N.3
Visioli, F.4
-
36
-
-
84884685914
-
Intracellular Ca signaling: a novel player in the canonical mTOR-controlled autophagy pathway
-
Decuypere J.P., Paudel R.C., Parys J., Bultynck G. Intracellular Ca signaling: a novel player in the canonical mTOR-controlled autophagy pathway. Commun Integr Biol 2013, 6:e25429.
-
(2013)
Commun Integr Biol
, vol.6
-
-
Decuypere, J.P.1
Paudel, R.C.2
Parys, J.3
Bultynck, G.4
-
37
-
-
79959982281
-
Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis
-
Onesto E., Rusmini P., Crippa V., Ferri N., Zito A., Galbiati M., et al. Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis. J Neurochem 2011, 118:266-280.
-
(2011)
J Neurochem
, vol.118
, pp. 266-280
-
-
Onesto, E.1
Rusmini, P.2
Crippa, V.3
Ferri, N.4
Zito, A.5
Galbiati, M.6
-
38
-
-
34250615454
-
The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts
-
Katsiki M., Chondrogianni N., Chinou I., Rivett A.J., Gonos E.S. The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts. Rejuvenation Res 2007, 10:157-172.
-
(2007)
Rejuvenation Res
, vol.10
, pp. 157-172
-
-
Katsiki, M.1
Chondrogianni, N.2
Chinou, I.3
Rivett, A.J.4
Gonos, E.S.5
-
39
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N., Yoshimori T., Levine B. Methods in mammalian autophagy research. Cell 2010, 140:313-326.
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
|