Free energy analysis of conductivity and charge selectivity of M2GlyR-derived synthetic channels

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 9, 2014, Pages 2319-2325

  Chen, Jianhan ^a   Tomich, John M ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Anion selectivity; Cystic fibrosis; Ion channels; Molecular dynamics; Peptide design; Potential of mean force

Indexed keywords

CHLORIDE ION; GLYCINE RECEPTOR; POTASSIUM ION; PROLYLALANYLARGINYLVALYLGLYCYLLEUCYLGLYCYLISOLEUCYLTHREONYLTHREONYLVALYLLEUCYLTHREONYLMETHIONYLTHREONYLTHREONYLGLUTAMINYLSERYLSERYLGLYCYLSERYLARGINYLALANINE; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANION SELECTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHARGE SELECTIVITY; CHEMICAL BINDING; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; ION CONDUCTANCE; ION TRANSPORT; MOLECULAR DYNAMICS; MUTAGENESIS; PERMEABILITY BARRIER; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; SIMULATION; STATIC ELECTRICITY; VOLTAGE CLAMP TECHNIQUE;

ANION SELECTIVITY; CYSTIC FIBROSIS; ION CHANNELS; MOLECULAR DYNAMICS; PEPTIDE DESIGN; POTENTIAL OF MEAN FORCE;

CELL MEMBRANE; CHLORIDES; CYSTIC FIBROSIS; HUMANS; ION CHANNELS; ION TRANSPORT; IONS; PEPTIDES; POTASSIUM; RECEPTORS, GLYCINE;

EID: 84903770867     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2014.02.016     Document Type: Article

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