Effect of diaminopropionic acid (Dap) on the biophysical properties of a modified synthetic channel-forming peptide

Molecular Pharmaceutics

Volumn 10, Issue 10, 2013, Pages 3959-3966

  Bukovnik, Urska ^a,c   Sala Rabanal, Monica ^b   Francis, Simonne ^b   Frazier, Shawnalea J ^a,d   Schultz, Bruce D ^a   Nichols, Colin G ^b   Tomich, John M ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Sandoz Pharmaceuticals   (Slovenia)

^d CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Anion channel; Channel replacement therapy; Chloride channel; Cystic fibrosis; Dap; Diaminopropionic acid; Glycine receptor alpha subunit; Ion permeation; Ion selectivity; Synthetic channel forming peptide

Indexed keywords

2,3 DIAMINOPROPIONIC ACID; ANION CHANNEL; CHANNEL FORMING PEPTIDE; CHLORIDE CHANNEL; GLYCINE RECEPTOR; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; CHANNEL GATING; CONTROLLED STUDY; ION PERMEABILITY; MDCK CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; VOLTAGE CLAMP;

BETA-ALANINE; ION CHANNELS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, GLYCINE;

EID: 84888374562     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4002377     Document Type: Article

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