메뉴 건너뛰기




Volumn 56, Issue 1, 2014, Pages 130-136

Evaluation of neurotransmitter receptor gene expression identifies GABA receptor changes: A follow-up study in antipsychotic-naïve patients with first-episode psychosis

Author keywords

GABA Rho 2; Gene expression; Risperidone; Schizophrenia

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR RHO 2; CATECHOL METHYLTRANSFERASE; CHOLINERGIC RECEPTOR NICOTINIC BETA 1 PROTEIN; CHOLINERGIC RECEPTOR NICOTINIC EPSILON PROTEIN; GTP CYCLOHYDROLASE I FEEDBACK REGULATOR PROTEIN; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; MESSENGER RNA; NEU DIFFERENTIATION FACTOR; NEUROTRANSMITTER RECEPTOR; RISPERIDONE; TACHYKININ RECEPTOR 2; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID A RECEPTOR; GABRR2 PROTEIN, HUMAN; NEUROLEPTIC AGENT;

EID: 84903763061     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2014.05.012     Document Type: Article
Times cited : (15)

References (53)
  • 2
    • 84896732939 scopus 로고    scopus 로고
    • Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults
    • Aberg K.A., McClay J.L., Nerella S., Clark S., Kumar G., Chen W., et al. Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults. JAMA Psychiatry 2014, 71:255-264.
    • (2014) JAMA Psychiatry , vol.71 , pp. 255-264
    • Aberg, K.A.1    McClay, J.L.2    Nerella, S.3    Clark, S.4    Kumar, G.5    Chen, W.6
  • 5
    • 0031799363 scopus 로고    scopus 로고
    • International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function
    • Barnard E.A., Skolnick P., Olsen R.W., Mohler H., Sieghart W., Biggio G., et al. International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Pharmacol Rev 1998, 50:291-313.
    • (1998) Pharmacol Rev , vol.50 , pp. 291-313
    • Barnard, E.A.1    Skolnick, P.2    Olsen, R.W.3    Mohler, H.4    Sieghart, W.5    Biggio, G.6
  • 6
    • 85012092311 scopus 로고    scopus 로고
    • Early intervention in psychosis. The critical period hypothesis
    • Birchwood M., Todd P., Jackson C. Early intervention in psychosis. The critical period hypothesis. Br J Psychiatry Suppl 1998, 172:53-59.
    • (1998) Br J Psychiatry Suppl , vol.172 , pp. 53-59
    • Birchwood, M.1    Todd, P.2    Jackson, C.3
  • 8
    • 84865862998 scopus 로고    scopus 로고
    • Epigenetics of psychoactive drugs
    • Boyadjieva N., Varadinova M. Epigenetics of psychoactive drugs. JPharm Pharmacol 2012, 64:1349-1358.
    • (2012) JPharm Pharmacol , vol.64 , pp. 1349-1358
    • Boyadjieva, N.1    Varadinova, M.2
  • 9
    • 79957478245 scopus 로고    scopus 로고
    • Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype
    • Breuer R., Hamshere M.L., Strohmaier J., Mattheisen M., Degenhardt F., Meier S., et al. Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype. Mol Psychiatry 2011, 16:587-589.
    • (2011) Mol Psychiatry , vol.16 , pp. 587-589
    • Breuer, R.1    Hamshere, M.L.2    Strohmaier, J.3    Mattheisen, M.4    Degenhardt, F.5    Meier, S.6
  • 11
    • 77956422817 scopus 로고    scopus 로고
    • Elevated plasma gamma-aminobutyrate/glutamate ratio and responses to risperidone antipsychotic treatment in schizophrenia
    • Cai H.L., Zhu R.H., Li H.D., Zhang X.H., Hu L., Yang W., et al. Elevated plasma gamma-aminobutyrate/glutamate ratio and responses to risperidone antipsychotic treatment in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2010, 34:1273-1278.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , pp. 1273-1278
    • Cai, H.L.1    Zhu, R.H.2    Li, H.D.3    Zhang, X.H.4    Hu, L.5    Yang, W.6
  • 12
    • 59649088080 scopus 로고    scopus 로고
    • Novel, potent, and selective GABAC antagonists inhibit myopia development and facilitate learning and memory
    • Chebib M., Hinton T., Schmid K.L., Brinkworth D., Qian H., Matos S., et al. Novel, potent, and selective GABAC antagonists inhibit myopia development and facilitate learning and memory. JPharmacol Exp Ther 2009, 328:448-457.
    • (2009) JPharmacol Exp Ther , vol.328 , pp. 448-457
    • Chebib, M.1    Hinton, T.2    Schmid, K.L.3    Brinkworth, D.4    Qian, H.5    Matos, S.6
  • 13
    • 0027335518 scopus 로고
    • Irreversible blockade of D2 dopamine receptors by fluphenazine-N-mustard increases glutamic acid decarboxylase mRNA in rat striatum
    • Chen J.F., Weiss B. Irreversible blockade of D2 dopamine receptors by fluphenazine-N-mustard increases glutamic acid decarboxylase mRNA in rat striatum. Neurosci Lett 1993, 150:215-218.
    • (1993) Neurosci Lett , vol.150 , pp. 215-218
    • Chen, J.F.1    Weiss, B.2
  • 14
    • 0028949822 scopus 로고
    • Glutamate decarboxylase messenger RNA in rat pallidum: comparison of the effects of haloperidol, clozapine and combined haloperidol-scopolamine treatments
    • Delfs J.M., Anegawa N.J., Chesselet M.F. Glutamate decarboxylase messenger RNA in rat pallidum: comparison of the effects of haloperidol, clozapine and combined haloperidol-scopolamine treatments. Neuroscience 1995, 66:67-80.
    • (1995) Neuroscience , vol.66 , pp. 67-80
    • Delfs, J.M.1    Anegawa, N.J.2    Chesselet, M.F.3
  • 15
    • 79251555954 scopus 로고    scopus 로고
    • Antipsychotic-induced DRD2 upregulation and its prevention by alpha-lipoic acid in SH-SY5Y neuroblastoma cells
    • Deslauriers J., Lefrancois M., Larouche A., Sarret P., Grignon S. Antipsychotic-induced DRD2 upregulation and its prevention by alpha-lipoic acid in SH-SY5Y neuroblastoma cells. Synapse 2011, 65:321-331.
    • (2011) Synapse , vol.65 , pp. 321-331
    • Deslauriers, J.1    Lefrancois, M.2    Larouche, A.3    Sarret, P.4    Grignon, S.5
  • 17
    • 44649088160 scopus 로고    scopus 로고
    • The role of GABA(A) receptors in the development of alcoholism
    • Enoch M.A. The role of GABA(A) receptors in the development of alcoholism. Pharmacol Biochem Behav 2008, 90:95-104.
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 95-104
    • Enoch, M.A.1
  • 18
    • 84879977184 scopus 로고    scopus 로고
    • MRNA and protein expression for novel GABAA receptors theta and rho2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway
    • Fatemi S.H., Folsom T.D., Rooney R.J., Thuras P.D. mRNA and protein expression for novel GABAA receptors theta and rho2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl Psychiatry 2013, 3:e271.
    • (2013) Transl Psychiatry , vol.3
    • Fatemi, S.H.1    Folsom, T.D.2    Rooney, R.J.3    Thuras, P.D.4
  • 19
    • 0028977843 scopus 로고
    • GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits
    • Fritschy J.M., Mohler H. GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. JComp Neurol 1995, 359:154-194.
    • (1995) JComp Neurol , vol.359 , pp. 154-194
    • Fritschy, J.M.1    Mohler, H.2
  • 20
    • 12844258466 scopus 로고    scopus 로고
    • Opposing roles for GABAA and GABAC receptors in short-term memory formation in young chicks
    • Gibbs M.E., Johnston G.A. Opposing roles for GABAA and GABAC receptors in short-term memory formation in young chicks. Neuroscience 2005, 131:567-576.
    • (2005) Neuroscience , vol.131 , pp. 567-576
    • Gibbs, M.E.1    Johnston, G.A.2
  • 22
    • 0032504623 scopus 로고    scopus 로고
    • Unique activation of extracellular striato-pallidal neurotransmitters in rats following acute risperidone
    • Grimm J.W., See R.E. Unique activation of extracellular striato-pallidal neurotransmitters in rats following acute risperidone. Brain Res 1998, 801:182-189.
    • (1998) Brain Res , vol.801 , pp. 182-189
    • Grimm, J.W.1    See, R.E.2
  • 23
    • 0033759439 scopus 로고    scopus 로고
    • Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study
    • Guidotti A., Auta J., Davis J.M., Di-Giorgi-Gerevini V., Dwivedi Y., Grayson D.R., et al. Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Arch Gen Psychiatry 2000, 57:1061-1069.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 1061-1069
    • Guidotti, A.1    Auta, J.2    Davis, J.M.3    Di-Giorgi-Gerevini, V.4    Dwivedi, Y.5    Grayson, D.R.6
  • 24
    • 0021333321 scopus 로고
    • Association with persistent neuroleptic-induced dyskinesia of regional changes in brain GABA synthesis
    • Gunne L.M., Haggstrom J.E., Sjoquist B. Association with persistent neuroleptic-induced dyskinesia of regional changes in brain GABA synthesis. Nature 1984, 309:347-349.
    • (1984) Nature , vol.309 , pp. 347-349
    • Gunne, L.M.1    Haggstrom, J.E.2    Sjoquist, B.3
  • 25
    • 0037505200 scopus 로고    scopus 로고
    • The Clinical Global Impression-Schizophrenia scale: a simple instrument to measure the diversity of symptoms present in schizophrenia
    • Haro J.M., Kamath S.A., Ochoa S., Novick D., Rele K., Fargas A., et al. The Clinical Global Impression-Schizophrenia scale: a simple instrument to measure the diversity of symptoms present in schizophrenia. Acta Psychiatr Scand Suppl 2003, 16-23.
    • (2003) Acta Psychiatr Scand Suppl , pp. 16-23
    • Haro, J.M.1    Kamath, S.A.2    Ochoa, S.3    Novick, D.4    Rele, K.5    Fargas, A.6
  • 26
    • 84902537175 scopus 로고    scopus 로고
    • Altered cortical expression of GABA-related genes in Schizophrenia: Illness progression vs developmental disturbance
    • (in press)
    • Hoftman G.D., Volk D.W., Bazmi H.H., Li S., Sampson A.R., Lewis D.A. Altered cortical expression of GABA-related genes in Schizophrenia: Illness progression vs developmental disturbance. Schizophr Bull 2013, (in press).
    • (2013) Schizophr Bull
    • Hoftman, G.D.1    Volk, D.W.2    Bazmi, H.H.3    Li, S.4    Sampson, A.R.5    Lewis, D.A.6
  • 27
    • 70350664635 scopus 로고    scopus 로고
    • Identification of brain transcriptional variation reproduced in peripheral blood: an approach for mapping brain expression traits
    • Jasinska A.J., Service S., Choi O.W., DeYoung J., Grujic O., Kong S.Y., et al. Identification of brain transcriptional variation reproduced in peripheral blood: an approach for mapping brain expression traits. Hum Mol Genet 2009, 18:4415-4427.
    • (2009) Hum Mol Genet , vol.18 , pp. 4415-4427
    • Jasinska, A.J.1    Service, S.2    Choi, O.W.3    DeYoung, J.4    Grujic, O.5    Kong, S.Y.6
  • 28
    • 0027988006 scopus 로고
    • Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain
    • Johnson A.E., Liminga U., Liden A., Lindefors N., Gunne L.M., Wiesel F.A. Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain. Neuroscience 1994, 63:1003-1020.
    • (1994) Neuroscience , vol.63 , pp. 1003-1020
    • Johnson, A.E.1    Liminga, U.2    Liden, A.3    Lindefors, N.4    Gunne, L.M.5    Wiesel, F.A.6
  • 29
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987, 13:261-276.
    • (1987) Schizophr Bull , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 30
    • 0027316076 scopus 로고
    • Effects of risperidone on catalepsy and cerebral dopamine, serotonin and GABA metabolism in the rat: comparison with haloperidol
    • Kikumoto O., Okamoto Y., Hayakawa H., Yokota N., Kawai K., Motohashi N., et al. Effects of risperidone on catalepsy and cerebral dopamine, serotonin and GABA metabolism in the rat: comparison with haloperidol. Yakubutsu Seishin Kodo 1993, 13:39-42.
    • (1993) Yakubutsu Seishin Kodo , vol.13 , pp. 39-42
    • Kikumoto, O.1    Okamoto, Y.2    Hayakawa, H.3    Yokota, N.4    Kawai, K.5    Motohashi, N.6
  • 31
    • 84880560783 scopus 로고    scopus 로고
    • Gene expression profiling in treatment-naive schizophrenia patients identifies abnormalities in biological pathways involving AKT1 that are corrected by antipsychotic medication
    • Kumarasinghe N., Beveridge N.J., Gardiner E., Scott R.J., Yasawardene S., Perera A., et al. Gene expression profiling in treatment-naive schizophrenia patients identifies abnormalities in biological pathways involving AKT1 that are corrected by antipsychotic medication. Int J Neuropsychopharmacol 2013, 16:1483-1503.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 1483-1503
    • Kumarasinghe, N.1    Beveridge, N.J.2    Gardiner, E.3    Scott, R.J.4    Yasawardene, S.5    Perera, A.6
  • 32
    • 59449101948 scopus 로고    scopus 로고
    • The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes
    • Kundakovic M., Chen Y., Guidotti A., Grayson D.R. The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Mol Pharmacol 2009, 75:342-354.
    • (2009) Mol Pharmacol , vol.75 , pp. 342-354
    • Kundakovic, M.1    Chen, Y.2    Guidotti, A.3    Grayson, D.R.4
  • 33
    • 68949213816 scopus 로고    scopus 로고
    • Genome-wide expression analysis of peripheral blood identifies candidate biomarkers for schizophrenia
    • Kuzman M.R., Medved V., Terzic J., Krainc D. Genome-wide expression analysis of peripheral blood identifies candidate biomarkers for schizophrenia. JPsychiatr Res 2009, 43:1073-1077.
    • (2009) JPsychiatr Res , vol.43 , pp. 1073-1077
    • Kuzman, M.R.1    Medved, V.2    Terzic, J.3    Krainc, D.4
  • 34
    • 0028843997 scopus 로고
    • Differential regulation of mRNA levels encoding for the two isoforms of glutamate decarboxylase (GAD65 and GAD67) by dopamine receptors in the rat striatum
    • Laprade N., Soghomonian J.J. Differential regulation of mRNA levels encoding for the two isoforms of glutamate decarboxylase (GAD65 and GAD67) by dopamine receptors in the rat striatum. Brain Res Mol Brain Res 1995, 34:65-74.
    • (1995) Brain Res Mol Brain Res , vol.34 , pp. 65-74
    • Laprade, N.1    Soghomonian, J.J.2
  • 35
    • 64349118890 scopus 로고    scopus 로고
    • Definitions of response and remission in schizophrenia: recommendations for their use and their presentation
    • Leucht S., Davis J.M., Engel R.R., Kissling W., Kane J.M. Definitions of response and remission in schizophrenia: recommendations for their use and their presentation. Acta Psychiatr Scand Suppl 2009, 7-14.
    • (2009) Acta Psychiatr Scand Suppl , pp. 7-14
    • Leucht, S.1    Davis, J.M.2    Engel, R.R.3    Kissling, W.4    Kane, J.M.5
  • 37
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman J.E., Coyle J.T., Green R.W., Javitt D.C., Benes F.M., Heckers S., et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci 2008, 31:234-242.
    • (2008) Trends Neurosci , vol.31 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3    Javitt, D.C.4    Benes, F.M.5    Heckers, S.6
  • 38
    • 23944444250 scopus 로고    scopus 로고
    • Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism
    • Ma D.Q., Whitehead P.L., Menold M.M., Martin E.R., Ashley-Koch A.E., Mei H., et al. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. Am J Hum Genet 2005, 77:377-388.
    • (2005) Am J Hum Genet , vol.77 , pp. 377-388
    • Ma, D.Q.1    Whitehead, P.L.2    Menold, M.M.3    Martin, E.R.4    Ashley-Koch, A.E.5    Mei, H.6
  • 39
    • 21444436743 scopus 로고    scopus 로고
    • Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches
    • Middleton F.A., Pato C.N., Gentile K.L., McGann L., Brown A.M., Trauzzi M., et al. Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches. Am J Med Genet B Neuropsychiatr Genet 2005, 136B:12-25.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.136 B , pp. 12-25
    • Middleton, F.A.1    Pato, C.N.2    Gentile, K.L.3    McGann, L.4    Brown, A.M.5    Trauzzi, M.6
  • 40
    • 84888303969 scopus 로고    scopus 로고
    • Neurotransmitter receptor and regulatory gene expression in peripheral blood of Brazilian drug-naive first-episode psychosis patients before and after antipsychotic treatment
    • Ota V.K., Noto C., Gadelha A., Santoro M.L., Silva P.N., Melaragno M.I., et al. Neurotransmitter receptor and regulatory gene expression in peripheral blood of Brazilian drug-naive first-episode psychosis patients before and after antipsychotic treatment. Psychiatry Res 2013, 210:1290-1292.
    • (2013) Psychiatry Res , vol.210 , pp. 1290-1292
    • Ota, V.K.1    Noto, C.2    Gadelha, A.3    Santoro, M.L.4    Silva, P.N.5    Melaragno, M.I.6
  • 41
    • 0034736184 scopus 로고    scopus 로고
    • GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain
    • Pirker S., Schwarzer C., Wieselthaler A., Sieghart W., Sperk G. GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. Neuroscience 2000, 101:815-850.
    • (2000) Neuroscience , vol.101 , pp. 815-850
    • Pirker, S.1    Schwarzer, C.2    Wieselthaler, A.3    Sieghart, W.4    Sperk, G.5
  • 43
    • 0035136421 scopus 로고    scopus 로고
    • Traditional and new antipsychotic drugs differentially alter neurotransmission markers in basal ganglia-thalamocortical neural pathways
    • Sakai K., Gao X.M., Hashimoto T., Tamminga C.A. Traditional and new antipsychotic drugs differentially alter neurotransmission markers in basal ganglia-thalamocortical neural pathways. Synapse 2001, 39:152-160.
    • (2001) Synapse , vol.39 , pp. 152-160
    • Sakai, K.1    Gao, X.M.2    Hashimoto, T.3    Tamminga, C.A.4
  • 44
    • 81955161247 scopus 로고    scopus 로고
    • The first decade and beyond of transcriptional profiling in schizophrenia
    • Sequeira P.A., Martin M.V., Vawter M.P. The first decade and beyond of transcriptional profiling in schizophrenia. Neurobiol Dis 2012, 45:23-36.
    • (2012) Neurobiol Dis , vol.45 , pp. 23-36
    • Sequeira, P.A.1    Martin, M.V.2    Vawter, M.P.3
  • 45
    • 79956015810 scopus 로고    scopus 로고
    • SSRI augmentation of antipsychotic alters expression of GABA(A) receptor and related genes in PMC of schizophrenia patients
    • Silver H., Susser E., Danovich L., Bilker W., Youdim M., Goldin V., et al. SSRI augmentation of antipsychotic alters expression of GABA(A) receptor and related genes in PMC of schizophrenia patients. Int J Neuropsychopharmacol 2011, 14:573-584.
    • (2011) Int J Neuropsychopharmacol , vol.14 , pp. 573-584
    • Silver, H.1    Susser, E.2    Danovich, L.3    Bilker, W.4    Youdim, M.5    Goldin, V.6
  • 46
    • 84862605801 scopus 로고    scopus 로고
    • Altered cortical GABA neurotransmission in schizophrenia: insights into novel therapeutic strategies
    • Stan A.D., Lewis D.A. Altered cortical GABA neurotransmission in schizophrenia: insights into novel therapeutic strategies. Curr Pharm Biotechnol 2012, 13:1557-1562.
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 1557-1562
    • Stan, A.D.1    Lewis, D.A.2
  • 48
    • 75949115370 scopus 로고    scopus 로고
    • GABA concentration in schizophrenia patients and the effects of antipsychotic medication: a proton magnetic resonance spectroscopy study
    • Tayoshi S., Nakataki M., Sumitani S., Taniguchi K., Shibuya-Tayoshi S., Numata S., et al. GABA concentration in schizophrenia patients and the effects of antipsychotic medication: a proton magnetic resonance spectroscopy study. Schizophr Res 2010, 117:83-91.
    • (2010) Schizophr Res , vol.117 , pp. 83-91
    • Tayoshi, S.1    Nakataki, M.2    Sumitani, S.3    Taniguchi, K.4    Shibuya-Tayoshi, S.5    Numata, S.6
  • 50
    • 38549160659 scopus 로고    scopus 로고
    • Differential localization of GABAA receptor subunits within the substantia nigra of the human brain: an immunohistochemical study
    • Waldvogel H.J., Baer K., Gai W.P., Gilbert R.T., Rees M.I., Mohler H., et al. Differential localization of GABAA receptor subunits within the substantia nigra of the human brain: an immunohistochemical study. JComp Neurol 2008, 506:912-929.
    • (2008) JComp Neurol , vol.506 , pp. 912-929
    • Waldvogel, H.J.1    Baer, K.2    Gai, W.P.3    Gilbert, R.T.4    Rees, M.I.5    Mohler, H.6
  • 51
    • 78249259373 scopus 로고    scopus 로고
    • Agenome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder
    • Wang K.S., Liu X.F., Aragam N. Agenome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. Schizophr Res 2010, 124:192-199.
    • (2010) Schizophr Res , vol.124 , pp. 192-199
    • Wang, K.S.1    Liu, X.F.2    Aragam, N.3
  • 52
    • 0344033607 scopus 로고    scopus 로고
    • GABA and schizophrenia: a review of basic science and clinical studies
    • Wassef A., Baker J., Kochan L.D. GABA and schizophrenia: a review of basic science and clinical studies. JClin Psychopharmacol 2003, 23:601-640.
    • (2003) JClin Psychopharmacol , vol.23 , pp. 601-640
    • Wassef, A.1    Baker, J.2    Kochan, L.D.3
  • 53
    • 43549120199 scopus 로고    scopus 로고
    • Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia
    • Zhang H.X., Zhao J.P., Lv L.X., Li W.Q., Xu L., Ouyang X., et al. Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia. Neurosci Lett 2008, 438:1-5.
    • (2008) Neurosci Lett , vol.438 , pp. 1-5
    • Zhang, H.X.1    Zhao, J.P.2    Lv, L.X.3    Li, W.Q.4    Xu, L.5    Ouyang, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.