Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration

Mini-Reviews in Medicinal Chemistry

Volumn 14, Issue 5, 2014, Pages 393-400

  Schönhofen, Patrícia ^a,b   de Medeiros, Liana Marengo ^a,b   Chatain, Carolina Piletti ^a,b   Bristot, Ivi Juliana ^a,b   Klamt, Fábio ^a,b  

^a Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

^b National Institute of Science and Technology in Translational Medicine (INCT TM)   (Brazil)

Author keywords

ATP depletion; Cofilin 1; Cofilin actin rods; Neurodegeneration; ROS

Indexed keywords

ACTIN; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; AMYLOID BETA PROTEIN; CATECHOL METHYLTRANSFERASE; COFILIN; COFILIN 1; REACTIVE OXYGEN METABOLITE; TAU PROTEIN; CFL1 PROTEIN, HUMAN;

ACTIN FILAMENT; ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; AUTONOMIC NEUROPATHY; CELL DEATH; HUMAN; HUNTINGTON CHOREA; LIPID MEMBRANE; METABOLIC ACTIVITY ASSAY; NERVE DEGENERATION; NERVE FUNCTION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PHOSPHORYLATION; DEGENERATIVE DISEASE; METABOLISM;

ACTINS; COFILIN 1; HUMANS; NEURODEGENERATIVE DISEASES;

EID: 84903750485     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/1389557514666140506161458     Document Type: Article

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