-
1
-
-
33748869678
-
Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies
-
M. R. Horsman and D. W. Siemann, "Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies," Cancer Res. 66(24), 11520-11539 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.24
, pp. 11520-11539
-
-
Horsman, M.R.1
Siemann, D.W.2
-
2
-
-
85013312416
-
Tumor angiogenesis: Therapeutic Implications
-
J. Folkman, "Tumor angiogenesis: therapeutic Implications," N. Engl. J. Med. 285(21), 1182-1186 (1971).
-
(1971)
N. Engl. J. Med
, vol.285
, Issue.21
, pp. 1182-1186
-
-
Folkman, J.1
-
3
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
R. K. Jain, "Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy," Science 307(5706), 58-62 (2005).
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
4
-
-
0842311621
-
Vascular targeting agents as cancer therapeutics
-
P. E. Thorpe, "Vascular targeting agents as cancer therapeutics," Clin. Cancer Res. 10(2), 415-427 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.2
, pp. 415-427
-
-
Thorpe, P.E.1
-
5
-
-
12244292196
-
Differentiation and definition of vascular-targeted therapies
-
D. W. Siemann, M. C. Bibby, G. G. Dark, A. P. Dicker, F. A. L. M. Eskens, M. R. Horsman, D. Marmé, and P. M. Lorusso, "Differentiation and definition of vascular-targeted therapies," Clin. Cancer Res. 11(2 Pt 1), 416-420 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.2
, pp. 416-420
-
-
Siemann, D.W.1
Bibby, M.C.2
Dark, G.G.3
Dicker, A.P.4
Eskens, F.A.L.M.5
Horsman, M.R.6
Marmé, D.7
Lorusso, P.M.8
-
6
-
-
55449122145
-
Tumour vascular disrupting agents: Combating treatment resistance
-
G. M. Tozer, C. Kanthou, G. Lewis, V. E. Prise, B. Vojnovic, and S. A. Hill, "Tumour vascular disrupting agents: combating treatment resistance," Br. J. Radiol. 81(Spec No 1), S12-S20 (2008).
-
(2008)
Br. J. Radiol
, vol.81
, Issue.SPEC NO 1
, pp. S12-S20
-
-
Tozer, G.M.1
Kanthou, C.2
Lewis, G.3
Prise, V.E.4
Vojnovic, B.5
Hill, S.A.6
-
7
-
-
44849093414
-
A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with antiangiogenic and antitumour activities
-
J. G. Christensen, "A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with antiangiogenic and antitumour activities," Ann. Oncol. 18(Suppl 10), x3-x10 (2007).
-
(2007)
Ann. Oncol
, vol.18
, pp. x3-x10
-
-
Christensen, J.G.1
-
8
-
-
3843090808
-
Combretastatin family member OXI4503 induces tumor vascular collapse through the induction of endothelial apoptosis
-
Y. Z. Sheng, J. Y. Hua, K. G. Pinney, C. M. Garner, R. R. Kane, J. A. Prezioso, D. J. Chaplin, and K. Edvardsen, "Combretastatin family member OXI4503 induces tumor vascular collapse through the induction of endothelial apoptosis," Int. J. Cancer 111(4), 604-610 (2004).
-
(2004)
Int. J. Cancer
, vol.111
, Issue.4
, pp. 604-610
-
-
Sheng, Y.Z.1
Hua, J.Y.2
Pinney, K.G.3
Garner, C.M.4
Kane, R.R.5
Prezioso, J.A.6
Chaplin, D.J.7
Edvardsen, K.8
-
9
-
-
78649833819
-
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by tumor-vascular disrupting agents
-
D. W. Siemann, "The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by tumor-vascular disrupting agents," Cancer Treat. Rev. 37(1), 63-74 (2011).
-
(2011)
Cancer Treat. Rev
, vol.37
, Issue.1
, pp. 63-74
-
-
Siemann, D.W.1
-
10
-
-
78549270044
-
Antiangiogenic agents and targets: A perspective
-
B. A. Teicher, "Antiangiogenic agents and targets: a perspective," Biochem. Pharmacol. 81(1), 6-12 (2011).
-
(2011)
Biochem. Pharmacol
, vol.81
, Issue.1
, pp. 6-12
-
-
Teicher, B.A.1
-
11
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
P. Carmeliet and R. K. Jain, "Molecular mechanisms and clinical applications of angiogenesis," Nature 473(7347), 298-307 (2011).
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
12
-
-
84865649921
-
Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts
-
J. V. Gaustad, T. G. Simonsen, M. N. Leinaas, and E. K. Rofstad, "Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts," BMC Cancer 12(1), 388 (2012).
-
(2012)
BMC Cancer
, vol.12
, Issue.1
, pp. 388
-
-
Gaustad, J.V.1
Simonsen, T.G.2
Leinaas, M.N.3
Rofstad, E.K.4
-
13
-
-
49049086508
-
Dual targeting of tumor vasculature: Combining avastin and vascular disrupting agents (CA4P or OXi4503)
-
D. W. Siemann and W. Y. Shi, "Dual targeting of tumor vasculature: Combining avastin and vascular disrupting agents (CA4P or OXi4503)," Anticancer Res. 28(4B), 2027-2031 (2008).
-
(2008)
Anticancer Res
, vol.28
, Issue.4B
, pp. 2027-2031
-
-
Siemann, D.W.1
Shi, W.Y.2
-
14
-
-
27744553032
-
Targeting the tumor vasculature: Enhancing antitumor efficacy through combination treatment with ZD6126 and ZD6474
-
W. Y. Shi and D. W. Siemann, "Targeting the tumor vasculature: Enhancing antitumor efficacy through combination treatment with ZD6126 and ZD6474," In Vivo 19(6), 1045-1050 (2005).
-
(2005)
In Vivo
, vol.19
, Issue.6
, pp. 1045-1050
-
-
Shi, W.Y.1
Siemann, D.W.2
-
15
-
-
0042887593
-
Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate
-
H. L. Anderson, J. T. Yap, M. P. Miller, A. Robbins, T. Jones, and P. M. Price, "Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate," J. Clin. Oncol. 21(15), 2823-2830 (2003).
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.15
, pp. 2823-2830
-
-
Anderson, H.L.1
Yap, J.T.2
Miller, M.P.3
Robbins, A.4
Jones, T.5
Price, P.M.6
-
16
-
-
77956813949
-
Assessment of acute antivascular effects of vandetanib with high-resolution dynamic contrast-enhanced computed tomographic imaging in a human colon tumor xenograft model in the nude rat
-
J. H. Tai, J. Tessier, A. J. Ryan, L. Hoffman, X. Chen, and T. Y. Lee, "Assessment of acute antivascular effects of vandetanib with high-resolution dynamic contrast-enhanced computed tomographic imaging in a human colon tumor xenograft model in the nude rat," Neoplasia 12(9), 697-707 (2010).
-
(2010)
Neoplasia
, vol.12
, Issue.9
, pp. 697-707
-
-
Tai, J.H.1
Tessier, J.2
Ryan, A.J.3
Hoffman, L.4
Chen, X.5
Lee, T.Y.6
-
17
-
-
84871547926
-
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in preclinical studies of antivascular treatments
-
T. Nielsen, T. Wittenborn, and M. R. Horsman, "Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in preclinical studies of antivascular treatments," Pharmaceutics 4(4), 563-589 (2012).
-
(2012)
Pharmaceutics
, vol.4
, Issue.4
, pp. 563-589
-
-
Nielsen, T.1
Wittenborn, T.2
Horsman, M.R.3
-
18
-
-
41649097369
-
Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging
-
J. V. Gaustad, K. G. Brurberg, T. G. Simonsen, C. S. Mollatt, and E. K. Rofstad, "Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging," Neoplasia 10(4), 354-362 (2008).
-
(2008)
Neoplasia
, vol.10
, Issue.4
, pp. 354-362
-
-
Gaustad, J.V.1
Brurberg, K.G.2
Simonsen, T.G.3
Mollatt, C.S.4
Rofstad, E.K.5
-
19
-
-
77958153538
-
Optical small animal imaging in the drug discovery process
-
S. Dufort, L. Sancey, C. Wenk, V. Josserand, and J. L. Coll, "Optical small animal imaging in the drug discovery process," Biochim. Biophys. Acta 1798(12), 2266-2273 (2010).
-
(2010)
Biochim. Biophys. Acta
, vol.1798
, Issue.12
, pp. 2266-2273
-
-
Dufort, S.1
Sancey, L.2
Wenk, C.3
Josserand, V.4
Coll, J.L.5
-
20
-
-
80052405303
-
In vivo optical molecular imaging and analysis in mice using dorsal window chamber models applied to hypoxia, vasculature and fluorescent reporters
-
G. M. Palmer, A. N. Fontanella, S. Shan, G. Hanna, G. Zhang, C. L. Fraser, and M. W. Dewhirst, "In vivo optical molecular imaging and analysis in mice using dorsal window chamber models applied to hypoxia, vasculature and fluorescent reporters," Nat. Protoc. 6(9), 1355-1366 (2011).
-
(2011)
Nat. Protoc
, vol.6
, Issue.9
, pp. 1355-1366
-
-
Palmer, G.M.1
Fontanella, A.N.2
Shan, S.3
Hanna, G.4
Zhang, G.5
Fraser, C.L.6
Dewhirst, M.W.7
-
21
-
-
0038376001
-
Imaging of angiogenesis: From microscope to clinic
-
D. M. McDonald and P. L. Choyke, "Imaging of angiogenesis: from microscope to clinic," Nat. Med. 9(6), 713-725 (2003).
-
(2003)
Nat. Med
, vol.9
, Issue.6
, pp. 713-725
-
-
McDonald, D.M.1
Choyke, P.L.2
-
22
-
-
84873367643
-
Combination of spectral and fluorescence imaging microscopy for wide-field in vivo analysis of microvessel blood supply and oxygenation
-
J. A. Lee, R. T. Kozikowski, and B. S. Sorg, "Combination of spectral and fluorescence imaging microscopy for wide-field in vivo analysis of microvessel blood supply and oxygenation," Opt. Lett. 38(3), 332-334 (2013).
-
(2013)
Opt. Lett
, vol.38
, Issue.3
, pp. 332-334
-
-
Lee, J.A.1
Kozikowski, R.T.2
Sorg, B.S.3
-
23
-
-
77349113986
-
In vivo functional differences in microvascular response of 4T1 and Caki-1 tumors after treatment with OXi4503
-
M. Wankhede, C. Dedeugd, D. W. Siemann, and B. S. Sorg, "In vivo functional differences in microvascular response of 4T1 and Caki-1 tumors after treatment with OXi4503," Oncol. Rep. 23(3), 685-692 (2010).
-
(2010)
Oncol. Rep
, vol.23
, Issue.3
, pp. 685-692
-
-
Wankhede, M.1
Dedeugd, C.2
Siemann, D.W.3
Sorg, B.S.4
-
24
-
-
0042575345
-
Temporal heterogeneity in oxygen tension in human melanoma xenografts
-
K. G. Brurberg, B. A. Graff, and E. K. Rofstad, "Temporal heterogeneity in oxygen tension in human melanoma xenografts," Br. J. Cancer 89(2), 350-356 (2003).
-
(2003)
Br. J. Cancer
, vol.89
, Issue.2
, pp. 350-356
-
-
Brurberg, K.G.1
Graff, B.A.2
Rofstad, E.K.3
-
25
-
-
39149140393
-
A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber
-
K. S. Øye, G. Gulati, B. A. Graff, J. V. Gaustad, K. G. Brurberg, and E. K. Rofstad, "A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber," Microvasc. Res. 75(2), 179-187 (2008).
-
(2008)
Microvasc. Res
, vol.75
, Issue.2
, pp. 179-187
-
-
Øye, K.S.1
Gulati, G.2
Graff, B.A.3
Gaustad, J.V.4
Brurberg, K.G.5
Rofstad, E.K.6
-
26
-
-
20344391071
-
Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development
-
B. S. Sorg, B. J. Moeller, O. Donovan, Y. T. Cao, and M. W. Dewhirst, "Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development," J. Biomed. Opt. 10(4), 044004 (2005).
-
(2005)
J. Biomed. Opt
, vol.10
, Issue.4
, pp. 044004
-
-
Sorg, B.S.1
Moeller, B.J.2
Donovan, O.3
Cao, Y.T.4
Dewhirst, M.W.5
-
27
-
-
85012373035
-
Diffusion of Univalent Ions Across the Lamellae of Swollen Phospholipids
-
A. D. Bangham, M. M. Standish, and J. C. Watkins, "Diffusion of Univalent Ions Across the Lamellae of Swollen Phospholipids," J. Mol. Biol. 13(1), 238-252 (1965).
-
(1965)
J. Mol. Biol
, vol.13
, Issue.1
, pp. 238-252
-
-
Bangham, A.D.1
Standish, M.M.2
Watkins, J.C.3
-
28
-
-
0030749774
-
Near-simultaneous hemoglobin saturation and oxygen tension maps in mouse brain using an AOTF microscope
-
R. D. Shonat, E. S. Wachman, W. H. Niu, A. P. Koretsky, and D. L. Farkas, "Near-simultaneous hemoglobin saturation and oxygen tension maps in mouse brain using an AOTF microscope," Biophys. J. 73(3), 1223-1231 (1997).
-
(1997)
Biophys. J
, vol.73
, Issue.3
, pp. 1223-1231
-
-
Shonat, R.D.1
Wachman, E.S.2
Niu, W.H.3
Koretsky, A.P.4
Farkas, D.L.5
-
29
-
-
0029018909
-
Contribution of transient blood-flow to tumor hypoxia in mice
-
R. E. Durand and N. E. Lepard, "Contribution of transient blood-flow to tumor hypoxia in mice," Acta Oncol. (Madr.) 34(3), 317-323 (1995).
-
(1995)
Acta Oncol. (Madr.)
, vol.34
, Issue.3
, pp. 317-323
-
-
Durand, R.E.1
Lepard, N.E.2
-
30
-
-
80053420126
-
Temporal changes in microvessel leakiness during wound healing discriminated by in vivo fluorescence recovery after photobleaching
-
M. J. Machado and C. A. Mitchell, "Temporal changes in microvessel leakiness during wound healing discriminated by in vivo fluorescence recovery after photobleaching," J. Physiol. 589(19), 4681-4696 (2011).
-
(2011)
J. Physiol
, vol.589
, Issue.19
, pp. 4681-4696
-
-
Machado, M.J.1
Mitchell, C.A.2
-
31
-
-
42049088503
-
Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors
-
G. M. Tozer, S. Akerman, N. A. Cross, P. R. Barber, M. A. Björndahl, O. Greco, S. Harris, S. A. Hill, D. J. Honess, C. R. Ireson, K. L. Pettyjohn, V. E. Prise, C. C. Reyes-Aldasoro, C. Ruhrberg, D. T. Shima, and C. Kanthou, "Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors," Cancer Res. 68(7), 2301-2311 (2008).
-
(2008)
Cancer Res
, vol.68
, Issue.7
, pp. 2301-2311
-
-
Tozer, G.M.1
Akerman, S.2
Cross, N.A.3
Barber, P.R.4
Björndahl, M.A.5
Greco, O.6
Harris, S.7
Hill, S.A.8
Honess, D.J.9
Ireson, C.R.10
Pettyjohn, K.L.11
Prise, V.E.12
Reyes-Aldasoro, C.C.13
Ruhrberg, C.14
Shima, D.T.15
Kanthou, C.16
-
32
-
-
33644772618
-
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers
-
M. R. Dreher, W. G. Liu, C. R. Michelich, M. W. Dewhirst, F. Yuan, and A. Chilkoti, "Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers," J. Natl. Cancer Inst. 98(5), 335-344 (2006).
-
(2006)
J. Natl. Cancer Inst
, vol.98
, Issue.5
, pp. 335-344
-
-
Dreher, M.R.1
Liu, W.G.2
Michelich, C.R.3
Dewhirst, M.W.4
Yuan, F.5
Chilkoti, A.6
-
33
-
-
84860217696
-
Cancer imaging by optical coherence tomography: Preclinical progress and clinical potential
-
B. J. Vakoc, D. Fukumura, R. K. Jain, and B. E. Bouma, "Cancer imaging by optical coherence tomography: preclinical progress and clinical potential," Nat. Rev. Cancer 12(5), 363-368 (2012).
-
(2012)
Nat. Rev. Cancer
, vol.12
, Issue.5
, pp. 363-368
-
-
Vakoc, B.J.1
Fukumura, D.2
Jain, R.K.3
Bouma, B.E.4
-
34
-
-
81055157916
-
Wide-field functional imaging of blood flow and hemoglobin oxygen saturation in the rodent dorsal window chamber
-
A. J. Moy, S. M. White, E. S. Indrawan, J. Lotfi, M. J. Nudelman, S. J. Costantini, N. Agarwal, W. Jia, K. M. Kelly, B. S. Sorg, and B. Choi, "Wide-field functional imaging of blood flow and hemoglobin oxygen saturation in the rodent dorsal window chamber," Microvasc. Res. 82(3), 199-209 (2011).
-
(2011)
Microvasc. Res
, vol.82
, Issue.3
, pp. 199-209
-
-
Moy, A.J.1
White, S.M.2
Indrawan, E.S.3
Lotfi, J.4
Nudelman, M.J.5
Costantini, S.J.6
Agarwal, N.7
Jia, W.8
Kelly, K.M.9
Sorg, B.S.10
Choi, B.11
-
35
-
-
58149374685
-
Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia
-
P. B. Jones, H. K. Shin, D. A. Boas, B. T. Hyman, M. A. Moskowitz, C. Ayata, and A. K. Dunn, "Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia," J. Biomed. Opt. 13(4), 044007 (2008).
-
(2008)
J. Biomed. Opt
, vol.13
, Issue.4
, pp. 044007
-
-
Jones, P.B.1
Shin, H.K.2
Boas, D.A.3
Hyman, B.T.4
Moskowitz, M.A.5
Ayata, C.6
Dunn, A.K.7
-
36
-
-
59249101574
-
Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging
-
M. C. Skala, A. Fontanella, H. Hendargo, M. W. Dewhirst, and J. A. Izatt, "Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging," Opt. Lett. 34(3), 289-291 (2009).
-
(2009)
Opt. Lett
, vol.34
, Issue.3
, pp. 289-291
-
-
Skala, M.C.1
Fontanella, A.2
Hendargo, H.3
Dewhirst, M.W.4
Izatt, J.A.5
-
37
-
-
65249143377
-
Multimodal optical imaging of microvessel network convective oxygen transport dynamics
-
C. deDeugd, M. Wankhede, and B. S. Sorg, "Multimodal optical imaging of microvessel network convective oxygen transport dynamics," Appl. Opt. 48(10), D187-D197 (2009).
-
(2009)
Appl. Opt
, vol.48
, Issue.10
, pp. D187-D197
-
-
De Deugd, C.1
Wankhede, M.2
Sorg, B.S.3
-
38
-
-
84887155386
-
Quantitative mapping of hemodynamics in the lung, brain, and dorsal window chamber-grown tumors using a novel, automated algorithm
-
A. N. Fontanella, T. Schroeder, D. W. Hochman, R. E. Chen, G. Hanna, M. M. Haglund, T. W. Secomb, G. M. Palmer, and M. W. Dewhirst, "Quantitative mapping of hemodynamics in the lung, brain, and dorsal window chamber-grown tumors using a novel, automated algorithm," Microcirculation 20(8), 724-735 (2013).
-
(2013)
Microcirculation
, vol.20
, Issue.8
, pp. 724-735
-
-
Fontanella, A.N.1
Schroeder, T.2
Hochman, D.W.3
Chen, R.E.4
Hanna, G.5
Haglund, M.M.6
Secomb, T.W.7
Palmer, G.M.8
Dewhirst, M.W.9
-
39
-
-
12444297983
-
The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels
-
K. L. Osusky, D. E. Hallahan, A. Fu, F. Ye, Y. Shyr, and L. Geng, "The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels," Angiogenesis 7(3), 225-233 (2004).
-
(2004)
Angiogenesis
, vol.7
, Issue.3
, pp. 225-233
-
-
Osusky, K.L.1
Hallahan, D.E.2
Fu, A.3
Ye, F.4
Shyr, Y.5
Geng, L.6
-
40
-
-
0035417875
-
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: Intravital microscopy and measurement of vascular permeability
-
G. M. Tozer, V. E. Prise, J. Wilson, M. Cemazar, S. Shan, M. W. Dewhirst, P. R. Barber, B. Vojnovic, and D. J. Chaplin, "Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability," Cancer Res. 61(17), 6413-6422 (2001).
-
(2001)
Cancer Res
, vol.61
, Issue.17
, pp. 6413-6422
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Cemazar, M.4
Shan, S.5
Dewhirst, M.W.6
Barber, P.R.7
Vojnovic, B.8
Chaplin, D.J.9
-
41
-
-
79955797422
-
In-vivo visualization of tumor microvessel density and response to anti-angiogenic treatment by high resolution MRI in mice
-
R. T. Ullrich, J. F. Jikeli, M. Diedenhofen, P. Böhm-Sturm, M. Unruh, S. Vollmar, and M. Hoehn, "In-vivo visualization of tumor microvessel density and response to anti-angiogenic treatment by high resolution MRI in mice," PLoS ONE 6(5), e19592 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.5
-
-
Ullrich, R.T.1
Jikeli, J.F.2
Diedenhofen, M.3
Böhm-Sturm, P.4
Unruh, M.5
Vollmar, S.6
Hoehn, M.7
-
42
-
-
62549151252
-
Why are tumour blood vessels abnormal and why is it important to know?
-
J. A. Nagy, S. H. Chang, A. M. Dvorak, and H. F. Dvorak, "Why are tumour blood vessels abnormal and why is it important to know?" Br. J. Cancer 100(6), 865-869 (2009).
-
(2009)
Br. J. Cancer
, vol.100
, Issue.6
, pp. 865-869
-
-
Nagy, J.A.1
Chang, S.H.2
Dvorak, A.M.3
Dvorak, H.F.4
-
43
-
-
7444259131
-
Efficacy of combined antiangiogenic and vascular disrupting agents in treatment of solid tumors
-
D. W. Siemann and W. Y. Shi, "Efficacy of combined antiangiogenic and vascular disrupting agents in treatment of solid tumors," Int. J. Radiat. Oncol. Biol. Phys. 60(4), 1233-1240 (2004).
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys
, vol.60
, Issue.4
, pp. 1233-1240
-
-
Siemann, D.W.1
Shi, W.Y.2
-
44
-
-
77956324472
-
Leukemia regression by vascular disruption and antiangiogenic therapy
-
G. J. Madlambayan, A. M. Meacham, K. Hosaka, S. Mir, M. Jorgensen, E. W. Scott, D. W. Siemann, and C. R. Cogle, "Leukemia regression by vascular disruption and antiangiogenic therapy," Blood 116(9), 1539-1547 (2010).
-
(2010)
Blood
, vol.116
, Issue.9
, pp. 1539-1547
-
-
Madlambayan, G.J.1
Meacham, A.M.2
Hosaka, K.3
Mir, S.4
Jorgensen, M.5
Scott, E.W.6
Siemann, D.W.7
Cogle, C.R.8
-
45
-
-
84866335646
-
Reversing resistance to vascular-disrupting agents by blocking late mobilization of circulating endothelial progenitor cells
-
M. Taylor, F. Billiot, V. Marty, V. Rouffiac, P. Cohen, E. Tournay, P. Opolon, F. Louache, G. Vassal, C. Laplace-Builhé, P. Vielh, J. C. Soria, and F. Farace, "Reversing resistance to vascular-disrupting agents by blocking late mobilization of circulating endothelial progenitor cells," Cancer Discov. 2(5), 434-449 (2012).
-
(2012)
Cancer Discov
, vol.2
, Issue.5
, pp. 434-449
-
-
Taylor, M.1
Billiot, F.2
Marty, V.3
Rouffiac, V.4
Cohen, P.5
Tournay, E.6
Opolon, P.7
Louache, F.8
Vassal, G.9
Laplace-Builhé, C.10
Vielh, P.11
Soria, J.C.12
Farace, F.13
-
46
-
-
33746091695
-
Effect of the second-generation vascular disrupting agent OXi4503 on tumor vascularity
-
H. W. Salmon and D. W. Siemann, "Effect of the second-generation vascular disrupting agent OXi4503 on tumor vascularity," Clin. Cancer Res. 12(13), 4090-4094 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.13
, pp. 4090-4094
-
-
Salmon, H.W.1
Siemann, D.W.2
-
47
-
-
47649083031
-
Vascular targeting agent Oxi4503 inhibits tumor growth in a colorectal liver metastases model
-
C. Malcontenti-Wilson, L. Chan, M. Nikfarjam, V. Muralidharan, and C. Christophi, "Vascular targeting agent Oxi4503 inhibits tumor growth in a colorectal liver metastases model," J. Gastroenterol. Hepatol. 23(7 Pt 2), e96-e104 (2008).
-
(2008)
J. Gastroenterol. Hepatol
, vol.23
, Issue.7
, pp. e96-e104
-
-
Malcontenti-Wilson, C.1
Chan, L.2
Nikfarjam, M.3
Muralidharan, V.4
Christophi, C.5
-
48
-
-
0038576983
-
Oxi4503, a novel vascular targeting agent: Effects on blood flow and antitumor activity in comparison to combretastatin A-4 phosphate
-
J. Y. Hua, Y. Z. Sheng, K. G. Pinney, C. M. Garner, R. R. Kane, J. A. Prezioso, G. R. Pettit, D. J. Chaplin, and K. Edvardsen, "Oxi4503, a novel vascular targeting agent: Effects on blood flow and antitumor activity in comparison to combretastatin A-4 phosphate," Anticancer Res. 23(2B), 1433-1440 (2003).
-
(2003)
Anticancer Res
, vol.23
, Issue.2B
, pp. 1433-1440
-
-
Hua, J.Y.1
Sheng, Y.Z.2
Pinney, K.G.3
Garner, C.M.4
Kane, R.R.5
Prezioso, J.A.6
Pettit, G.R.7
Chaplin, D.J.8
Edvardsen, K.9
-
49
-
-
84868692077
-
Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments
-
L. Nguyen, T. Fifis, C. Malcontenti-Wilson, L. S. Chan, P. N. Costa, M. Nikfarjam, V. Muralidharan, and C. Christophi, "Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments," BMC Cancer 12(1), 522 (2012).
-
(2012)
BMC Cancer
, vol.12
, Issue.1
, pp. 522
-
-
Nguyen, L.1
Fifis, T.2
Malcontenti-Wilson, C.3
Chan, L.S.4
Costa, P.N.5
Nikfarjam, M.6
Muralidharan, V.7
Christophi, C.8
-
50
-
-
19944422751
-
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
-
F. Winkler, S. V. Kozin, R. T. Tong, S. S. Chae, M. F. Booth, I. Garkavtsev, L. Xu, D. J. Hicklin, D. Fukumura, E. di Tomaso, L. L. Munn, and R. K. Jain, "Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases," Cancer Cell 6(6), 553-563 (2004).
-
(2004)
Cancer Cell
, vol.6
, Issue.6
, pp. 553-563
-
-
Winkler, F.1
Kozin, S.V.2
Tong, R.T.3
Chae, S.S.4
Booth, M.F.5
Garkavtsev, I.6
Xu, L.7
Hicklin, D.J.8
Fukumura, D.9
Di Tomaso, E.10
Munn, L.L.11
Jain, R.K.12
-
51
-
-
60549117718
-
Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy
-
M. Czabanka, M. Vinci, F. Heppner, A. Ullrich, and P. Vajkoczy, "Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy," Int. J. Cancer 124(6), 1293-1300 (2009).
-
(2009)
Int. J. Cancer
, vol.124
, Issue.6
, pp. 1293-1300
-
-
Czabanka, M.1
Vinci, M.2
Heppner, F.3
Ullrich, A.4
Vajkoczy, P.5
-
52
-
-
69249149975
-
Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Vascular Changes Induced by Sunitinib in Papillary Renal Cell Carcinoma Xenograft Tumors
-
G. G. Hillman, V. Singh-Gupta, H. Zhang, A. K. Al-Bashir, Y. Katkuri, M. Li, C. K. Yunker, A. D. Patel, J. Abrams, and E. M. Haacke, "Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Vascular Changes Induced by Sunitinib in Papillary Renal Cell Carcinoma Xenograft Tumors," Neoplasia 11(9), 910-920 (2009).
-
(2009)
Neoplasia
, vol.11
, Issue.9
, pp. 910-920
-
-
Hillman, G.G.1
Singh-Gupta, V.2
Zhang, H.3
Al-Bashir, A.K.4
Katkuri, Y.5
Li, M.6
Yunker, C.K.7
Patel, A.D.8
Abrams, J.9
Haacke, E.M.10
-
53
-
-
16844366291
-
Improving delivery of antineoplastic agents with anti-vascular endothelial growth factor therapy
-
A. D. Yang, T. W. Bauer, E. R. Camp, R. Somcio, W. B. Liu, F. Fan, and L. M. Ellis, "Improving delivery of antineoplastic agents with anti-vascular endothelial growth factor therapy," Cancer 103(8), 1561-1570 (2005).
-
(2005)
Cancer
, vol.103
, Issue.8
, pp. 1561-1570
-
-
Yang, A.D.1
Bauer, T.W.2
Camp, E.R.3
Somcio, R.4
Liu, W.B.5
Fan, F.6
Ellis, L.M.7
-
54
-
-
80054020825
-
Antiangiogenic agent sunitinib transiently increases tumor oxygenation and suppresses cycling hypoxia
-
S. Matsumoto, S. Batra, K. Saito, H. Yasui, R. Choudhuri, C. Gadisetti, S. Subramanian, N. Devasahayam, J. P. Munasinghe, J. B. Mitchell, and M. C. Krishna, "Antiangiogenic agent sunitinib transiently increases tumor oxygenation and suppresses cycling hypoxia," Cancer Res. 71(20), 6350-6359 (2011).
-
(2011)
Cancer Res
, vol.71
, Issue.20
, pp. 6350-6359
-
-
Matsumoto, S.1
Batra, S.2
Saito, K.3
Yasui, H.4
Choudhuri, R.5
Gadisetti, C.6
Subramanian, S.7
Devasahayam, N.8
Munasinghe, J.P.9
Mitchell, J.B.10
Krishna, M.C.11
-
55
-
-
0029035872
-
Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors
-
T. W. Secomb, R. Hsu, E. T. Ong, J. F. Gross, and M. W. Dewhirst, "Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors," Acta Oncol. 34(3), 313-316 (1995).
-
(1995)
Acta Oncol
, vol.34
, Issue.3
, pp. 313-316
-
-
Secomb, T.W.1
Hsu, R.2
Ong, E.T.3
Gross, J.F.4
Dewhirst, M.W.5
-
56
-
-
85055509470
-
Dual-agent targeting of the tumor vasculature: Combining avastin with CA4P or OXi4503
-
D. W. Siemann and W. Shi, "Dual-agent targeting of the tumor vasculature: combining avastin with CA4P or OXi4503," Clin. Cancer Res. 11, 8968S (2005).
-
(2005)
Clin. Cancer Res
, vol.11
-
-
Siemann, D.W.1
Shi, W.2
-
57
-
-
84863888220
-
Combining antiangiogenics to overcome resistance: Rationale and clinical experience
-
V. Moreno Garcia, B. Basu, L. R. Molife, and S. B. Kaye, "Combining antiangiogenics to overcome resistance: rationale and clinical experience," Clin. Cancer Res. 18(14), 3750-3761 (2012).
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.14
, pp. 3750-3761
-
-
Garcia, M.V.1
Basu, B.2
Molife, L.R.3
Kaye, S.B.4
-
58
-
-
84862532904
-
Phase I trial of combretastatin A4 phosphate (CA4P) in combination with bevacizumab in patients with advanced cancer
-
P. Nathan, M. Zweifel, A. R. Padhani, D. M. Koh, M. Ng, D. J. Collins, A. Harris, C. Carden, J. Smythe, N. Fisher, N. J. Taylor, J. J. Stirling, S. P. Lu, M. O. Leach, G. J. S. Rustin, and I. Judson, "Phase I trial of combretastatin A4 phosphate (CA4P) in combination with bevacizumab in patients with advanced cancer," Clin. Cancer Res. 18(12), 3428-3439 (2012).
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.12
, pp. 3428-3439
-
-
Nathan, P.1
Zweifel, M.2
Padhani, A.R.3
Koh, D.M.4
Ng, M.5
Collins, D.J.6
Harris, A.7
Carden, C.8
Smythe, J.9
Fisher, N.10
Taylor, N.J.11
Stirling, J.J.12
Lu, S.P.13
Leach, M.O.14
Rustin, G.J.S.15
Judson, I.16
|