Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts

BMC Cancer

Volumn 12, Issue , 2012, Pages

  Gaustad, Jon Vidar ^a   Simonsen, Trude G ^a   Leinaas, Marit N ^a   Rofstad, Einar K ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Antiangiogenic treatment; Intravital microscopy; Sunitinib; Tumor hypoxia; Vascular normalization

Indexed keywords

SUNITINIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD VESSEL DIAMETER; CANCER CELL DESTRUCTION; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER MORPHOLOGY; CANCER SIZE; CELL HYPOXIA; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOLOGY; MELANOMA; MOUSE; NONHUMAN; SHORT COURSE THERAPY; TUMOR VASCULARIZATION; TUMOR XENOGRAFT;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; BASEMENT MEMBRANE; BLOOD VESSELS; CELL HYPOXIA; FEMALE; HUMANS; INDOLES; MELANOMA; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; PYRROLES; SPHEROIDS, CELLULAR; TUMOR BURDEN; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865649921     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-12-388     Document Type: Article

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