SAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin

EMBO Reports

Volumn 15, Issue 7, 2014, Pages 809-815

  McCarthy, Ryan C ^a   Park, Yun Hee ^a   Kosman, Daniel J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

blood brain barrier; brain iron metabolism; ferroportin; iron transport; sAPP

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CERULOPLASMIN; FERROPORTIN; FERROUS ION; OXYGEN; AMYLOID BETA PROTEIN; CATION TRANSPORT PROTEIN; IRON; METAL TRANSPORTING PROTEIN 1; PROTEIN BINDING;

ALZHEIMER DISEASE; AMYLOID PLAQUE; APOPTOSIS; ARTICLE; ASTROCYTE; AUTOOXIDATION; BRAIN TISSUE; CATALYST; CELL MEMBRANE; CHANNELOPATHY; CONTROLLED STUDY; ENZYME ACTIVITY; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTERSTITIUM; IRON TRANSPORT; ISOTHERMAL TITRATION CALORIMETRY; MICROVASCULAR ENDOTHELIAL CELL; OXYGEN CONSUMPTION; PRIORITY JOURNAL; STIMULATION; AMINO ACID SEQUENCE; BRAIN; CHEMISTRY; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; PROTEIN DOMAIN; UMBILICAL VEIN ENDOTHELIAL CELL;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; BRAIN; CATION TRANSPORT PROTEINS; CERULOPLASMIN; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IRON; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84903720548     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201338064     Document Type: Article

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