A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells

Brain Research

Volumn 1521, Issue , 2013, Pages 16-30

  Patabendige, Adjanie ^a,d   Skinner, Robert A ^b   Morgan, Louise ^a,c   Joan Abbott, N ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c EISAI CO LTD   (Japan)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Blood brain barrier; Brain endothelium; In vitro model; Permeability; Tight junction; Transendothelial electrical resistance

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; HYDROCORTISONE; IRINOTECAN; MANNITOL; MANNITOL C 14; TIGHT JUNCTION PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN CAPILLARY; BRAIN FUNCTION; CELL CULTURE; CELL FUNCTION; CELL GROWTH; CELL INTERACTION; CELL ISOLATION; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; DRUG PENETRATION; DRUG SCREENING; DRUG TRANSPORT; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROENVIRONMENT; MONOCULTURE; NONHUMAN; PERICYTE; PHENOTYPE; PORCINE BRAIN ENDOTHELIAL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCIBILITY; SWINE; TRANSCYTOSIS; TRANSENDOTHELIAL ELECTRICAL RESISTANCE;

ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CELL CULTURE TECHNIQUES; CELLS, CULTURED; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; MODELS, ANIMAL; SWINE; TIGHT JUNCTIONS;

MAMMALIA; SUS;

EID: 84879317348     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.04.006     Document Type: Article

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