-
1
-
-
75749096347
-
The endocytic matrix
-
Scita, G., and Di Fiore, P. P. (2010) The endocytic matrix. Nature 463, 464-473
-
(2010)
Nature
, vol.463
, pp. 464-473
-
-
Scita, G.1
Di Fiore, P.P.2
-
2
-
-
74749099537
-
The early endosome: A busy sorting station for proteins at the crossroads
-
Jovic, M., Sharma, M., Rahajeng, J., and Caplan, S. (2010) The early endosome: a busy sorting station for proteins at the crossroads. Histol. Histopathol. 25, 99-112
-
(2010)
Histol. Histopathol.
, vol.25
, pp. 99-112
-
-
Jovic, M.1
Sharma, M.2
Rahajeng, J.3
Caplan, S.4
-
3
-
-
79151485206
-
Secretory and endo/exocytic trafficking in invadopodia formation: The MT1-MMP paradigm
-
Frittoli, E., Palamidessi, A., Disanza, A., and Scita, G. (2011) Secretory and endo/exocytic trafficking in invadopodia formation: the MT1-MMP paradigm. Eur. J. Cell Biol. 90, 108-114
-
(2011)
Eur. J. Cell Biol.
, vol.90
, pp. 108-114
-
-
Frittoli, E.1
Palamidessi, A.2
Disanza, A.3
Scita, G.4
-
4
-
-
80054018901
-
Cell polarity and migration: Emerging role for the endosomal sorting machinery
-
Lobert, V. H., and Stenmark, H. (2011) Cell polarity and migration: emerging role for the endosomal sorting machinery. Physiology (Bethesda) 26, 171-180
-
(2011)
Physiology (Bethesda)
, vol.26
, pp. 171-180
-
-
Lobert, V.H.1
Stenmark, H.2
-
5
-
-
37049019067
-
Late endosomal traffic of the epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling
-
DOI 10.1091/mbc.E07-02-0098
-
Taub, N., Teis, D., Ebner, H. L., Hess, M. W., and Huber, L. A. (2007) Late endosomal traffic of the epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling. Mol. Biol. Cell 18, 4698-4710 (Pubitemid 350246673)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.12
, pp. 4698-4710
-
-
Taub, N.1
Teis, D.2
Ebner, H.L.3
Hess, M.W.4
Huber, L.A.5
-
6
-
-
46149125934
-
Endocytic trafficking of rac is required for the spatial restriction of signaling in cell migration
-
DOI 10.1016/j.cell.2008.05.034, PII S009286740800696X
-
Palamidessi, A., Frittoli, E., Garre, M., Faretta, M., Mione, M., Testa, I., Diaspro, A., Lanzetti, L., Scita, G., and Di Fiore, P. P. (2008) Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration. Cell 134, 135-147 (Pubitemid 351905741)
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 135-147
-
-
Palamidessi, A.1
Frittoli, E.2
Garre, M.3
Faretta, M.4
Mione, M.5
Testa, I.6
Diaspro, A.7
Lanzetti, L.8
Scita, G.9
Di Fiore, P.P.10
-
7
-
-
69249137477
-
Endocytosis and signalling: Intertwining molecular networks
-
Sorkin, A., and von Zastrow, M. (2009) Endocytosis and signalling: intertwining molecular networks. Nat. Rev. Mol. Cell Biol. 10, 609-622
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 609-622
-
-
Sorkin, A.1
Von Zastrow, M.2
-
8
-
-
22944447140
-
Signaling and endocytosis: A team effort for cell migration
-
DOI 10.1016/j.devcel.2005.07.007, PII S1534580705002601
-
Le Roy, C., and Wrana, J. L. (2005) Signaling and endocytosis: a team effort for cell migration. Dev. Cell 9, 167-168 (Pubitemid 41051734)
-
(2005)
Developmental Cell
, vol.9
, Issue.2
, pp. 167-168
-
-
Le Roy, C.1
Wrana, J.L.2
-
9
-
-
70449552889
-
Endosomes: A legitimate platform for the signaling train
-
Murphy, J. E., Padilla, B. E., Hasdemir, B., Cottrell, G. S., and Bunnett, N. W. (2009) Endosomes: a legitimate platform for the signaling train. Proc. Natl. Acad. Sci. U.S.A. 106, 17615-17622
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
Padilla, B.E.2
Hasdemir, B.3
Cottrell, G.S.4
Bunnett, N.W.5
-
10
-
-
62849097694
-
New roles for endosomes: From vesicular carriers to multi-purpose platforms
-
Gould, G. W., and Lippincott-Schwartz, J. (2009) New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nat. Rev. Mol. Cell Biol. 10, 287-292
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 287-292
-
-
Gould, G.W.1
Lippincott-Schwartz, J.2
-
12
-
-
77951724799
-
The Ras-ERK pathway: Understanding site-specific signaling provides hope of new anti-tumor therapies
-
Calvo, F., Agudo-Ibanez, L., and Crespo, P. (2010) The Ras-ERK pathway: understanding site-specific signaling provides hope of new anti-tumor therapies. Bioessays 32, 412-421
-
(2010)
Bioessays
, vol.32
, pp. 412-421
-
-
Calvo, F.1
Agudo-Ibanez, L.2
Crespo, P.3
-
13
-
-
67949088074
-
Ras/MAPK signaling from endomembranes
-
Fehrenbacher, N., Bar-Sagi, D., and Philips, M. (2009) Ras/MAPK signaling from endomembranes. Mol. Oncol. 3, 297-307
-
(2009)
Mol. Oncol.
, vol.3
, pp. 297-307
-
-
Fehrenbacher, N.1
Bar-Sagi, D.2
Philips, M.3
-
14
-
-
36248934768
-
Interactions of Ras proteins with the plasma membrane and their roles in signaling
-
DOI 10.1016/j.cellsig.2007.07.012, PII S0898656807002276
-
Eisenberg, S., and Henis, Y. I. (2008) Interactions of Ras proteins with the plasma membrane and their roles in signaling. Cell. Signal. 20, 31-39 (Pubitemid 350138367)
-
(2008)
Cellular Signalling
, vol.20
, Issue.1
, pp. 31-39
-
-
Eisenberg, S.1
Henis, Y.I.2
-
15
-
-
33845313646
-
2 lipids target proteins with polybasic clusters to the plasma membrane
-
DOI 10.1126/science.1134389
-
Heo, W. D., Inoue, T., Park, W. S., Kim, M. L., Park, B. O., Wandless, T. J., and Meyer, T. (2006) PI(3, 4, 5)P3 and PI(4, 5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314, 1458-1461 (Pubitemid 44871952)
-
(2006)
Science
, vol.314
, Issue.5804
, pp. 1458-1461
-
-
Won, D.H.1
Inoue, T.2
Wei, S.P.3
Man, L.K.4
Byung, O.P.5
Wandless, T.J.6
Meyer, T.7
-
16
-
-
84858796808
-
Ras trafficking, localization and compartmentalized signalling
-
Prior, I. A., and Hancock, J. F. (2012) Ras trafficking, localization and compartmentalized signalling. Semin. CellDev. Biol. 23, 145-153
-
(2012)
Semin. CellDev. Biol.
, vol.23
, pp. 145-153
-
-
Prior, I.A.1
Hancock, J.F.2
-
17
-
-
20144375061
-
An acylation cycle regulates localization and activity of palmitoylated ras isoforms
-
DOI 10.1126/science.1105654
-
Rocks, O., Peyker, A., Kahms, M., Verveer, P. J., Koerner, C, Lumbierres, M., Kuhlmann, J., Waldmann, H., Wittinghofer, A., and Bastiaens, P. I. (2005) An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 307, 1746-1752 (Pubitemid 40388611)
-
(2005)
Science
, vol.307
, Issue.5716
, pp. 1746-1752
-
-
Rocks, O.1
Peyker, A.2
Kahms, M.3
Verveer, P.J.4
Koerner, C.5
Lumbierres, M.6
Kuhlmann, J.7
Waldmann, H.8
Wittinghofer, A.9
Bastiaens, P.I.H.10
-
18
-
-
77955838654
-
Spatial cycles in G-protein crowd control
-
Vartak, N., and Bastiaens, P. (2010) Spatial cycles in G-protein crowd control. EMBOJ. 29, 2689-2699
-
(2010)
EMBOJ.
, vol.29
, pp. 2689-2699
-
-
Vartak, N.1
Bastiaens, P.2
-
19
-
-
30044431691
-
K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes
-
DOI 10.1091/mbc.E05-05-0408
-
Silvius, J. R., Bhagatji, P., Leventis, R., and Terrone, D. (2006) K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes. Mol. Biol. Cell 17, 192-202 (Pubitemid 43049473)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.1
, pp. 192-202
-
-
Silvius, J.R.1
Bhagatji, P.2
Leventis, R.3
Terrone, D.4
-
20
-
-
84856492497
-
The GDI-like solubilizing factor PDEdelta sustains the spatial organization and signalling of Ras family proteins
-
Chandra, A., Grecco, H. E., Pisupati, V., Perera, D., Cassidy, L., Skoulidis, F., Ismail, S. A., Hedberg, C, Hanzal-Bayer, M., Venkitaraman, A. R., Wittinghofer, A., and Bastiaens, P. I. (2012) The GDI-like solubilizing factor PDEdelta sustains the spatial organization and signalling of Ras family proteins. Nat. Cell Biol. 14, 148-158
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 148-158
-
-
Chandra, A.1
Grecco, H.E.2
Pisupati, V.3
Perera, D.4
Cassidy, L.5
Skoulidis, F.6
Ismail, S.A.7
Hedberg, C.8
Hanzal-Bayer, M.9
Venkitaraman, A.R.10
Wittinghofer, A.11
Bastiaens, P.I.12
-
21
-
-
0029742203
-
Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement
-
Yokoe, H., andMeyer, T. (1996) Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement. Nat. Biotechnol. 14, 1252-1256 (Pubitemid 26332785)
-
(1996)
Nature Biotechnology
, vol.14
, Issue.10
, pp. 1252-1256
-
-
Yokoe, H.1
Meyer, T.2
-
22
-
-
0033555935
-
Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies
-
Niv, H., Gutman, O., Henis, Y I., and Kloog, Y (1999) Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies. J. Biol. Chem. 274, 1606-1613
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1606-1613
-
-
Niv, H.1
Gutman, O.2
Henis, Y.I.3
Kloog, Y.4
-
23
-
-
0037182579
-
Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells
-
DOI 10.1083/jcb.200202009
-
Niv, H., Gutman, O., Kloog, Y., and Henis, Y I. (2002) Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells. J. Cell Biol. 157, 865-872 (Pubitemid 34847823)
-
(2002)
Journal of Cell Biology
, vol.157
, Issue.5
, pp. 865-872
-
-
Niv, H.1
Gutman, O.2
Kloog, Y.3
Henis, Y.I.4
-
24
-
-
78649263874
-
Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane
-
Bhagatji, P., Leventis, R., Rich, R., Lin, C. J., and Silvius, J. R (2010) Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. Biophys. J. 99, 3327-3335
-
(2010)
Biophys. J.
, vol.99
, pp. 3327-3335
-
-
Bhagatji, P.1
Leventis, R.2
Rich, R.3
Lin, C.J.4
Silvius, J.R.5
-
25
-
-
55249103396
-
Differential interference of chlorpromazine with the membrane interactions of oncogenic K-Ras and its effects on cell growth
-
Eisenberg, S., Giehl, K., Henis, Y. I., and Ehrlich, M. (2008) Differential interference of chlorpromazine with the membrane interactions of oncogenic K-Ras and its effects on cell growth. J. Biol. Chem. 283, 27279-27288
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27279-27288
-
-
Eisenberg, S.1
Giehl, K.2
Henis, Y.I.3
Ehrlich, M.4
-
26
-
-
4544295231
-
Galectin-3 augments K-ras activation and triggers a ras signal that attenuates ERK but not phosphoinositide 3-kinase activity
-
DOI 10.1074/jbc.M312697200
-
Elad-Sfadia, G., Haklai, R., Balan, E., and Kloog, Y. (2004) Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. J. Biol. Chem. 279, 34922-34930 (Pubitemid 39318128)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.33
, pp. 34922-34930
-
-
Elad-Sfadia, G.1
Haklai, R.2
Balan, E.3
Kloog, Y.4
-
27
-
-
0035958898
-
Prenylated Rab acceptor protein is a receptor for prenylated small GTPases
-
Figueroa, C., Taylor, J., and Vojtek, A. B. (2001) Prenylated Rab acceptor protein is a receptor for prenylated small GTPases. J. Biol. Chem. 276, 28219-28225
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28219-28225
-
-
Figueroa, C.1
Taylor, J.2
Vojtek, A.B.3
-
28
-
-
23744505102
-
2+/calmodulin
-
DOI 10.1083/jcb.200409157
-
Fivaz, M., and Meyer, T. (2005) Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin. J. Cell Biol. 170, 429-441 (Pubitemid 41126942)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.3
, pp. 429-441
-
-
Fivaz, M.1
Meyer, T.2
-
29
-
-
44849117286
-
Identification of essential interacting elements in K-Ras/calmodulin binding and its role in K-Ras localization
-
Lopez-Alcala, C., Alvarez-Moya, B., Villalonga, P., Calvo, M., Bachs, O., and Agell, N. (2008) Identification of essential interacting elements in K-Ras/calmodulin binding and its role in K-Ras localization. J. Biol. Chem. 283, 10621-10631
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10621-10631
-
-
Lopez-Alcala, C.1
Alvarez-Moya, B.2
Villalonga, P.3
Calvo, M.4
Bachs, O.5
Agell, N.6
-
30
-
-
0037177881
-
The δ subunit of retinal rod cGMP phosphodiesterase regulates the membrane association of Ras and Rap GTpases
-
DOI 10.1074/jbc.M109983200
-
Nancy, V., Callebaut, I., El Marjou, A., and de Gunzburg, J. (2002) The delta subunit of retinal rod cGMP phosphodiesterase regulates the membrane association of Ras and Rap GTPases. J. Biol. Chem. 277, 15076-15084 (Pubitemid 34952585)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.17
, pp. 15076-15084
-
-
Nancy, V.1
Callebaut, I.2
Marjou, A.E.3
De Gunzburg, J.4
-
31
-
-
0034790751
-
Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling
-
DOI 10.1128/MCB.21.21.7345-7354.2001
-
Villalonga, P., Lopez-Alcala, C., Bosch, M., Chiloeches, A., Rocamora, N., Gil, J., Marais, R., Marshall, C. J., Bachs, O., and Agell, N. (2001) Calmodulin binds to K-Ras, but not to H-or N-Ras, and modulates its downstream signaling. Mol. Cell. Biol. 21, 7345-7354 (Pubitemid 32953487)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.21
, pp. 7345-7354
-
-
Villalonga, P.1
Lopez-Alcala, C.2
Bosch, M.3
Chiloeches, A.4
Rocamora, N.5
Gil, J.6
Marais, R.7
Marshall, C.J.8
Bachs, O.9
Agell, N.10
-
32
-
-
84856497818
-
Ras hitchhikes on PDE6delta
-
Philips, M. R. (2012) Ras hitchhikes on PDE6delta. Nat. CellBiol. 14, 128-129
-
(2012)
Nat. CellBiol.
, vol.14
, pp. 128-129
-
-
Philips, M.R.1
-
33
-
-
0035999983
-
Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells
-
DOI 10.1091/mbc.01-11-0552
-
Jiang, X., and Sorkin, A. (2002) Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. Mol. Biol. Cell 13, 1522-1535 (Pubitemid 34522636)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.5
, pp. 1522-1535
-
-
Jiang, X.1
Sorkin, A.2
-
34
-
-
64049096198
-
A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes
-
Lu, A., Tebar, F., Alvarez-Moya, B., Lopez-Alcala, C, Calvo, M., Enrich, C, Agell, N., Nakamura, T., Matsuda, M., and Bachs, O. (2009) A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes. J. Cell Biol. 184, 863-879
-
(2009)
J. Cell Biol.
, vol.184
, pp. 863-879
-
-
Lu, A.1
Tebar, F.2
Alvarez-Moya, B.3
Lopez-Alcala, C.4
Calvo, M.5
Enrich, C.6
Agell, N.7
Nakamura, T.8
Matsuda, M.9
Bachs, O.10
-
35
-
-
79956007102
-
CaM interaction and Ser181 phosphorylation as new K-Ras signaling modulators
-
Alvarez-Moya, B., Barcelo, C., Tebar, F., Jaumot, M., and Agell, N. (2011) CaM interaction and Ser181 phosphorylation as new K-Ras signaling modulators. Small GTPases 2, 99-103
-
(2011)
Small GTPases
, vol.2
, pp. 99-103
-
-
Alvarez-Moya, B.1
Barcelo, C.2
Tebar, F.3
Jaumot, M.4
Agell, N.5
-
36
-
-
32444441115
-
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
-
DOI 10.1016/j.molcel.2006.01.012, PII S1097276506000323
-
Bivona, T. G., Quatela, S. E., Bodemann, B. O., Ahearn, I. M., Soskis, M. J., Mor, A., Miura, J., Wiener, H. H., Wright, L., Saba, S. G., Yim, D., Fein, A., Perez de Castro, I., Li, C., Thompson, C. B., Cox, A. D., and Philips, M. R. (2006) PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. Mol. Cell 21, 481-493 (Pubitemid 43228004)
-
(2006)
Molecular Cell
, vol.21
, Issue.4
, pp. 481-493
-
-
Bivona, T.G.1
Quatela, S.E.2
Bodemann, B.O.3
Ahearn, I.M.4
Soskis, M.J.5
Mor, A.6
Miura, J.7
Wiener, H.H.8
Wright, L.9
Saba, S.G.10
Yim, D.11
Fein, A.12
Perez De Castro, I.13
Li, C.14
Thompson, C.B.15
Cox, A.D.16
Philips, M.R.17
-
37
-
-
0034282751
-
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
-
Gillooly, D. J., Morrow, I. C, Lindsay, M., Gould, R, Bryant, N. J., Gaullier, J. M., Parton, R. G., and Stenmark, H. (2000) Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBOJ. 19, 4577-4588
-
(2000)
EMBOJ.
, vol.19
, pp. 4577-4588
-
-
Gillooly, D.J.1
Morrow, I.C.2
Lindsay, M.3
Gould, R.4
Bryant, N.J.5
Gaullier, J.M.6
Parton, R.G.7
Stenmark, H.8
-
38
-
-
79961113678
-
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine
-
Fairn, G. D., Schieber, N. L., Ariotti, N., Murphy, S., Kuerschner, L., Webb, R I., Grinstein, S., and Parton, R. G. (2011) High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J. Cell Biol. 194, 257-275
-
(2011)
J. Cell Biol.
, vol.194
, pp. 257-275
-
-
Fairn, G.D.1
Schieber, N.L.2
Ariotti, N.3
Murphy, S.4
Kuerschner, L.5
Webb, R.I.6
Grinstein, S.7
Parton, R.G.8
-
39
-
-
77952944942
-
The distribution and function of phosphatidylserine in cellular membranes
-
Leventis, P. A., and Grinstein, S. (2010) The distribution and function of phosphatidylserine in cellular membranes. Annu. Rev. Biophys. 39, 407-427
-
(2010)
Annu. Rev. Biophys.
, vol.39
, pp. 407-427
-
-
Leventis, P.A.1
Grinstein, S.2
-
40
-
-
84871538883
-
Staurosporines disrupt phosphatidylserine trafficking and mis-localize Ras proteins
-
Cho, K.J., Park, J. H., Piggott, A. M., Salim, A. A., Gorfe, A. A., Parton, R G., Capon, R J., Lacey, E., and Hancock, J. F. (2012) Staurosporines disrupt phosphatidylserine trafficking and mis-localize Ras proteins. J. Biol. Chem. 287, 43573-43584
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 43573-43584
-
-
Cho, K.J.1
Park, J.H.2
Piggott, A.M.3
Salim, A.A.4
Gorfe, A.A.5
Parton, R.G.6
Capon, R.J.7
Lacey, E.8
Hancock, J.F.9
-
41
-
-
38149094836
-
Membrane phosphatidylserine regulates surface charge and protein localization
-
Yeung, T., Gilbert, G. E., Shi, J., Silvius, J., Kapus, A., and Grinstein, S. (2008) Membrane phosphatidylserine regulates surface charge and protein localization. Science 319, 210-213
-
(2008)
Science
, vol.319
, pp. 210-213
-
-
Yeung, T.1
Gilbert, G.E.2
Shi, J.3
Silvius, J.4
Kapus, A.5
Grinstein, S.6
-
42
-
-
40949127740
-
Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain
-
DOI 10.1242/jcs.020107
-
Laude, A. J., and Prior, I. A. (2008) Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain. J. Cell Sci. 121, 421-427 (Pubitemid 351405050)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.4
, pp. 421-427
-
-
Laude, A.J.1
Prior, I.A.2
-
43
-
-
48249151809
-
Spatiotemporal activation of Rac1 for engulfment of apopto-tic cells
-
Nakaya, M., Kitano, M., Matsuda, M., and Nagata, S. (2008) Spatiotemporal activation of Rac1 for engulfment of apopto-tic cells. Proc. Natl. Acad. Sci. U.S.A. 105, 9198-9203
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 9198-9203
-
-
Nakaya, M.1
Kitano, M.2
Matsuda, M.3
Nagata, S.4
-
44
-
-
84863205849
-
NIH Image to ImageJ: 25 years of image analysis
-
Schneider, C. A., Rasband, W. S., and Eliceiri, K W. (2012) NIH Image to ImageJ: 25 years of image analysis. Nat. Methods 9, 671-675
-
(2012)
Nat. Methods
, vol.9
, pp. 671-675
-
-
Schneider, C.A.1
Rasband, W.S.2
Eliceiri, K.W.3
-
45
-
-
6344225446
-
Protein kinaseCδ-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes
-
DOI 10.1091/mbc.E04-02-0127
-
Lladó, A., Tebar, F., Calvo, M., Moretó, J., Sorkin, A., and Enrich, C. (2004) Protein kinase CÔ-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes. Mol. Biol. Cell 15, 4877-4891 (Pubitemid 39392204)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.11
, pp. 4877-4891
-
-
Llado, A.1
Tebar, F.2
Calvo, M.3
Moreto, J.4
Sorkin, A.5
Enrich, C.6
-
46
-
-
0017184389
-
Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. (1976) Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
47
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
48
-
-
0035408008
-
Ras-activated endocytosis is mediated by the rab5 guanine nucleotide exchange activity of RIN1
-
DOI 10.1016/S1534-5807(01)00008-9, PII S1534580701000089
-
Tall, G. G., Barbieri, M. A., Stahl, P. D., and Horazdovsky, B. F. (2001) Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. Dev. Cell 1, 73-82 (Pubitemid 33586070)
-
(2001)
Developmental Cell
, vol.1
, Issue.1
, pp. 73-82
-
-
Tall, G.G.1
Barbieri, M.A.2
Stahl, P.D.3
Horazdovsky, B.F.4
-
49
-
-
0033202945
-
Rab5 regulates motility of early endosomes on microtubules
-
Nielsen, E., Severin, F., Backer, J. M., Hyman, A. A., and Zerial, M. (1999) Rab5 regulates motility of early endosomes on microtubules. Nat. Cell Biol. 1, 376-382 (Pubitemid 129493581)
-
(1999)
Nature Cell Biology
, vol.1
, Issue.6
, pp. 376-382
-
-
Nielsen, E.1
Severin, F.2
Backer, J.M.3
Hyman, A.A.4
Zerial, M.5
-
50
-
-
80052511996
-
Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis
-
Flores-Rodriguez, N., Rogers, S. S., Kenwright, D. A., Waigh, T. A., Woodman, P. G., and Allan, V.J. (2011) Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis. PLoS One 6, e24479
-
(2011)
PLoS One
, vol.6
-
-
Flores-Rodriguez, N.1
Rogers, S.S.2
Kenwright, D.A.3
Waigh, T.A.4
Woodman, P.G.5
Allan, V.J.6
-
51
-
-
40449103751
-
Different microtubule motors move early and late endocytic compartments
-
DOI 10.1111/j.1600-0854.2008.00704.x
-
Loubery, S., Wilhelm, C, Hurbain, I., Neveu, S., Louvard, D., and Coudrier, E. (2008) Different microtubule motors move early and late endocytic compartments. Traffic 9, 492-509 (Pubitemid 351351611)
-
(2008)
Traffic
, vol.9
, Issue.4
, pp. 492-509
-
-
Loubery, S.1
Wilhelm, C.2
Hurbain, I.3
Neveu, S.4
Louvard, D.5
Coudrier, E.6
-
52
-
-
33847413103
-
Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer
-
DOI 10.1021/jm061053f
-
Gorfe, A. A., Hanzal-Bayer, M., Abankwa, D., Hancock, J. F., and McCammon, J. A. (2007) Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1, 2-dimyristoylglycero-3-phosphocholine bilayer. J. Med. Chem. 50, 674-684 (Pubitemid 46332980)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.4
, pp. 674-684
-
-
Gorfe, A.A.1
Hanzal-Bayer, M.2
Abankwa, D.3
Hancock, J.F.4
McCammon, J.A.5
-
53
-
-
0028968896
-
Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes
-
Shahinian, S., and Silvius, J. R. (1995) Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes. Biochemistry 34, 3813-3822
-
(1995)
Biochemistry
, vol.34
, pp. 3813-3822
-
-
Shahinian, S.1
Silvius, J.R.2
-
54
-
-
84862753776
-
A palmitoyl-ation switch mechanism regulates Rac1 function and membrane organization
-
Navarro-Lerida, I., Sanchez-Perales, S., Calvo, M., Rentero, C., Zheng, Y., Enrich, C., and Del Pozo, M. A. (2012) A palmitoyl-ation switch mechanism regulates Rac1 function and membrane organization. EMBO J. 31, 534-551
-
(2012)
EMBO J.
, vol.31
, pp. 534-551
-
-
Navarro-Lerida, I.1
Sanchez-Perales, S.2
Calvo, M.3
Rentero, C.4
Zheng, Y.5
Enrich, C.6
Del Pozo, M.A.7
-
55
-
-
0141433284
-
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
-
DOI 10.1083/jcb.200303018
-
Petiot, A., Faure, J., Stenmark, H., and Gruenberg, J. (2003) PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J. Cell Biol. 162, 971-979 (Pubitemid 37174182)
-
(2003)
Journal of Cell Biology
, vol.162
, Issue.6
, pp. 971-979
-
-
Petiot, A.1
Faure, J.2
Stenmark, H.3
Gruenberg, J.4
-
56
-
-
0034062812
-
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
-
DOI 10.1128/MCB.20.7.2475-2487.2000
-
Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G., and Hancock, J. F. (2000) H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. Mol. Cell. Biol. 20, 2475-2487 (Pubitemid 30152055)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.7
, pp. 2475-2487
-
-
Apolloni, A.1
Prior, I.A.2
Lindsay, M.3
Parton, R.G.4
Hancock, J.F.5
-
57
-
-
75749150934
-
Ras membrane orientation and nanodomain localization generate isoform diversity
-
Abankwa, D., Gorfe, A. A., Inder, K., and Hancock, J. F. (2010) Ras membrane orientation and nanodomain localization generate isoform diversity. Proc. Natl. Acad. Sci. U.S.A. 107, 1130-1135
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 1130-1135
-
-
Abankwa, D.1
Gorfe, A.A.2
Inder, K.3
Hancock, J.F.4
-
58
-
-
40949130399
-
A novel switch region regulates H-ras membrane orientation and signal output
-
DOI 10.1038/emboj.2008.10, PII EMBOJ200810
-
Abankwa, D., Hanzal-Bayer, M., Ariotti, N., Plowman, S. J., Gorfe, A. A., Parton, R. G., McCammon, J. A., and Hancock, J. F. (2008) A novel switch region regulates H-ras membrane orientation and signal output. EMBO J. 27, 727-735 (Pubitemid 351506675)
-
(2008)
EMBO Journal
, vol.27
, Issue.5
, pp. 727-735
-
-
Abankwa, D.1
Hanzal-Bayer, M.2
Ariotti, N.3
Plowman, S.J.4
Gorfe, A.A.5
Parton, R.G.6
McCammon, J.A.7
Hancock, J.F.8
-
59
-
-
0025013547
-
A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
-
Hancock, J. F., Paterson, H., and Marshall, C. J. (1990) A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 63, 133-139
-
(1990)
Cell
, vol.63
, pp. 133-139
-
-
Hancock, J.F.1
Paterson, H.2
Marshall, C.J.3
-
60
-
-
0033538559
-
Endomembrane trafficking of ras: The CAAX motif targets proteins to the ER and Golgi
-
DOI 10.1016/S0092-8674(00)80607-8
-
Choy, E., Chiu, V. K., Silletti, J., Feoktistov, M., Morimoto, T., Michaelson, D., Ivanov, I. E., and Philips, M. R. (1999) Endo-membrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi. Cell 98, 69-80 (Pubitemid 29331197)
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 69-80
-
-
Choy, E.1
Chiu, V.K.2
Silletti, J.3
Feoktistov, M.4
Morimoto, T.5
Michaelson, D.6
Ivanov, I.E.7
Philips, M.R.8
-
61
-
-
0034682560
-
Mutational and biochemical analysis of plasma membrane targeting mediated by the farnesylated, polybasic carboxy terminus of K-ras4B
-
DOI 10.1021/bi000512q
-
Roy, M. O., Leventis, R., and Silvius, J. R. (2000) Mutational and biochemical analysis of plasma membrane targeting mediated by the farnesylated, polybasic carboxy terminus of K-ras4B. Biochemistry 39, 8298-8307 (Pubitemid 30460982)
-
(2000)
Biochemistry
, vol.39
, Issue.28
, pp. 8298-8307
-
-
Roy, M.-O.1
Leventis, R.2
Silvius, J.R.3
-
62
-
-
0032546549
-
Lipid-binding characteristics of the polybasic carboxy-terminal sequence of K-ras4B
-
DOI 10.1021/bi973077h
-
Leventis, R., and Silvius, J. R. (1998) Lipid-binding characteristics of the polybasic carboxy-terminal sequence of K-ras4B. Biochemistry 37, 7640-7648 (Pubitemid 28235248)
-
(1998)
Biochemistry
, vol.37
, Issue.20
, pp. 7640-7648
-
-
Leventis, R.1
Silvius, J.R.2
-
63
-
-
0036300306
-
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
-
DOI 10.1034/j.1600-0854.2002.30605.x
-
Murray, J. T., Panaretou, C., Stenmark, H., Miaczynska, M., and Backer, J. M. (2002) Role of Rab5 in the recruitment of hVps34/p150 to the early endosome. Traffic 3, 416-427 (Pubitemid 34746409)
-
(2002)
Traffic
, vol.3
, Issue.6
, pp. 416-427
-
-
Murray, J.T.1
Panaretou, C.2
Stenmark, H.3
Miaczynska, M.4
Backer, J.M.5
-
64
-
-
23944437499
-
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
-
DOI 10.1083/jcb.200505128
-
Shin, H. W., Hayashi, M., Christoforidis, S., Lacas-Gervais, S., Hoepfner, S., Wenk, M. R., Modregger, J., Uttenweiler-Joseph, S., Wilm, M., Nystuen, A., Frankel, W. N., Solimena, M., De Camilli, P., and Zerial, M. (2005) An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endo-cytic pathway. J. Cell Biol. 170, 607-618 (Pubitemid 41186935)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.4
, pp. 607-618
-
-
Shin, H.-W.1
Hayashi, M.2
Christoforidis, S.3
Lacas-Gervais, S.4
Hoepfner, S.5
Wenk, M.R.6
Modregger, J.7
Uttenweiler-Joseph, S.8
Wilm, M.9
Nystuen, A.10
Frankel, W.N.11
Solimena, M.12
De Camilli, P.13
Zerial, M.14
-
65
-
-
33645078650
-
Regulation of membrane traffic by phosphoinositide 3-kinases
-
Lindmo, K., and Stenmark, H. (2006) Regulation of membrane traffic by phosphoinositide 3-kinases. J. Cell Sci. 119, 605-614
-
(2006)
J. Cell Sci.
, vol.119
, pp. 605-614
-
-
Lindmo, K.1
Stenmark, H.2
-
66
-
-
0035899829
-
A Ptdlns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
-
DOI 10.1016/S0960-9822(01)00486-9
-
Pattni, K., Jepson, M., Stenmark, H., and Banting, G. (2001) A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells. Curr. Biol. 11, 1636-1642 (Pubitemid 32978532)
-
(2001)
Current Biology
, vol.11
, Issue.20
, pp. 1636-1642
-
-
Pattni, K.1
Jepson, M.2
Stenmark, H.3
Banting, G.4
-
67
-
-
0034911881
-
Synthesis and function of 3-phosphorylated inositol lipids
-
DOI 10.1146/annurev.biochem.70.1.535
-
Vanhaesebroeck, B., Leevers, S. J., Ahmadi, K., Timms, J., Katso, R., Driscoll, P. C., Woscholski, R., Parker, P. J., and Waterfield, M. D. (2001) Synthesis and function of 3-phosphorylated inosi-tol lipids. Annu. Rev. Biochem. 70, 535-602 (Pubitemid 32662219)
-
(2001)
Annual Review of Biochemistry
, vol.70
, pp. 535-602
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Ahmadi, K.3
Timms, J.4
Katso, R.5
Driscoll, P.C.6
Woscholski, R.7
Parker, P.J.8
Waterfield, M.D.9
-
68
-
-
0033122886
-
Localization of a class II phosphatidylinositol 3-kinase, PI3KC2α, to clathrin-coated vesicles
-
Prior, I. A., and Clague, M. J. (1999) Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles. Mol. Cell Biol. Res. Commun. 1, 162-166 (Pubitemid 129533209)
-
(1999)
Molecular Cell Biology Research Communications
, vol.1
, Issue.2
, pp. 162-166
-
-
Prior, I.A.1
Clague, M.J.2
|