Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder

EMBO Molecular Medicine

Volumn 6, Issue 7, 2014, Pages 937-951

  Friedrich, Corinna ^a   Rinné, Susanne ^b   Zumhagen, Sven ^a   Kiper, Aytug K ^b   Silbernagel, Nicole ^b   Netter, Michael F ^b   Stallmeyer, Birgit ^a   Schulze Bahr, Eric ^a   Decher, Niels ^b  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Arrhythmia; Progressive cardiac conduction disorder; SCN5A

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL TASK 4; UNCLASSIFIED DRUG; KCNK17 PROTEIN, HUMAN; SCN5A PROTEIN, HUMAN; SODIUM CHANNEL NAV1.5; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDUCTANCE; EXOME; GAIN OF FUNCTION MUTATION; GENE; HEART ARRHYTHMIA; HEART MUSCLE CONDUCTION DISTURBANCE; HEART VENTRICLE FIBRILLATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; HYPERPOLARIZATION; MAJOR CLINICAL STUDY; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PURKINJE CELL; VELOCITY; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; COHORT ANALYSIS; COMPLICATION; FEMALE; GENETICS; GENOTYPE; HEART MUSCLE; HEART MUSCLE CONDUCTION SYSTEM; MALE; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; PATHOLOGY; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; ARRHYTHMIAS, CARDIAC; CELL LINE; COHORT STUDIES; FEMALE; GENOTYPE; HEART CONDUCTION SYSTEM; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; MYOCARDIUM; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; VENTRICULAR FIBRILLATION; XENOPUS;

EID: 84903708200     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201303783     Document Type: Article

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