The inhibition of the potassium channel TASK-1 in rat cardiac muscle by endothelin-1 is mediated by phospholipase C

Cardiovascular Research

Volumn 97, Issue 1, 2013, Pages 97-105

  Schiekel, Julia ^a   Lindner, Moritz ^a   Hetzel, Andrea ^a   Wemhöner, Konstantin ^a   Renigunta, Vijay ^a   Schlichthörl, Günter ^a   Decher, Niels ^a   Oliver, Dominik ^a   Daut, Jürgen ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Cardiac action potential; Cardiomyocytes; K2P channels; Phospholipase C; U73122

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL (4,5) BISPHOSPHATE; PHOSPHOLIPASE C; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL TASK 1; RHO KINASE; UNCLASSIFIED DRUG;

ACIDIFICATION; ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART MUSCLE; MICROSCOPY; NONHUMAN; PATCH CLAMP; PH; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ENDOTHELIN-1; ENZYME ACTIVATION; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; ION CHANNEL GATING; KINETICS; MICROSCOPY, FLUORESCENCE; MICROSCOPY, INTERFERENCE; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RATS; RECEPTOR, ENDOTHELIN A; SIGNAL TRANSDUCTION; TRANSFECTION; TYPE C PHOSPHOLIPASES;

EID: 84871754628     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs285     Document Type: Article

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