-
1
-
-
33745571528
-
Immunotoxin therapy of cancer
-
Pastan, I., R. Hassan, D. J. Fitzgerald, and R. J. Kreitman. 2006. Immunotoxin therapy of cancer. Nat. Rev. Cancer 6: 559-565.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 559-565
-
-
Pastan, I.1
Hassan, R.2
Fitzgerald, D.J.3
Kreitman, R.J.4
-
2
-
-
0024349836
-
A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin
-
DOI 10.1038/339394a0
-
Chaudhary, V. K., C. Queen, R. P. Junghans, T. A. Waldmann, D. J. FitzGerald, and I. Pastan. 1989. A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin. Nature 339: 394-397. (Pubitemid 19144230)
-
(1989)
Nature
, vol.339
, Issue.6223
, pp. 394-397
-
-
Chaudhary, V.K.1
Queen, C.2
Junghans, R.P.3
Waldmann, T.A.4
Fitzgerald, D.J.5
Pastan, I.6
-
3
-
-
0035954624
-
Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia
-
Kreitman, R. J., W. H. Wilson, K. Bergeron, M. Raggio, M. Stetler-Stevenson, D. J. FitzGerald, and I. Pastan. 2001. Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. N. Engl. J. Med. 345: 241-247.
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 241-247
-
-
Kreitman, R.J.1
Wilson, W.H.2
Bergeron, K.3
Raggio, M.4
Stetler-Stevenson, M.5
Fitzgerald, D.J.6
Pastan, I.7
-
4
-
-
77949679970
-
Anti- CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: Preclinical studies and phase i clinical trial
-
Wayne, A. S., R. J. Kreitman, H. W. Findley, G. Lew, C. Delbrook, S. M. Steinberg, M. Stetler-Stevenson, D. J. Fitzgerald, and I. Pastan. 2010. Anti- CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial. Clin. Cancer Res. 16: 1894-1903.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 1894-1903
-
-
Wayne, A.S.1
Kreitman, R.J.2
Findley, H.W.3
Lew, G.4
Delbrook, C.5
Steinberg, S.M.6
Stetler-Stevenson, M.7
Fitzgerald, D.J.8
Pastan, I.9
-
5
-
-
0034001076
-
Phase i trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies
-
Kreitman, R. J., W. H. Wilson, J. D. White, M. Stetler-Stevenson, E. S. Jaffe, S. Giardina, T. A. Waldmann, and I. Pastan. 2000. Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. J. Clin. Oncol. 18: 1622-1636.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 1622-1636
-
-
Kreitman, R.J.1
Wilson, W.H.2
White, J.D.3
Stetler-Stevenson, M.4
Jaffe, E.S.5
Giardina, S.6
Waldmann, T.A.7
Pastan, I.8
-
6
-
-
69349100450
-
Phase i trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P
-
Kreitman, R. J., R. Hassan, D. J. Fitzgerald, and I. Pastan. 2009. Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P. Clin. Cancer Res. 15: 5274-5279.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5274-5279
-
-
Kreitman, R.J.1
Hassan, R.2
Fitzgerald, D.J.3
Pastan, I.4
-
7
-
-
34548858453
-
Phase i study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V infusion to patients with mesothelinexpressing mesothelioma, ovarian, and pancreatic cancers
-
Hassan,R., S.Bullock,A. Premkumar,R. J. Kreitman,H.Kindler,M.C. Willingham, and I. Pastan. 2007. Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelinexpressing mesothelioma, ovarian, and pancreatic cancers. Clin. Cancer Res. 13: 5144-5149.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5144-5149
-
-
Hassan, R.1
Bullock, S.2
Premkumar, A.3
Kreitman, R.J.4
Kindler, H.5
Willingham, M.C.6
Pastan, I.7
-
8
-
-
36749029362
-
Immunotoxin and Taxol synergy results from a decrease in shed mesothelin levels in the extracellular space of tumors
-
Zhang, Y. J., L. M. Xiang, R. Hassan, and I. Pastan. 2007. Immunotoxin and Taxol synergy results from a decrease in shed mesothelin levels in the extracellular space of tumors. Proc. Natl. Acad. Sci. USA 104: 17099-17104.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 17099-17104
-
-
Zhang, Y.J.1
Xiang, L.M.2
Hassan, R.3
Pastan, I.4
-
9
-
-
33748070220
-
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice
-
Zhang, Y., L. Xiang, R. Hassan, C. H. Paik, J. A. Carrasquillo, B. S. Jang, N. Le, M. Ho, and I. Pastan. 2006. Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice. Clin. Cancer Res. 12: 4695-4701.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 4695-4701
-
-
Zhang, Y.1
Xiang, L.2
Hassan, R.3
Paik, C.H.4
Carrasquillo, J.A.5
Jang, B.S.6
Le, N.7
Ho, M.8
Pastan, I.9
-
10
-
-
67649933809
-
Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia
-
Kreitman, R. J., M. Stetler-Stevenson, I. Margulies, P. Noel, D. J. Fitzgerald, W. H. Wilson, and I. Pastan. 2009. Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia. J. Clin. Oncol. 27: 2983-2990.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2983-2990
-
-
Kreitman, R.J.1
Stetler-Stevenson, M.2
Margulies, I.3
Noel, P.4
Fitzgerald, D.J.5
Wilson, W.H.6
Pastan, I.7
-
11
-
-
0034682480
-
Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity
-
Tsutsumi, Y., M. Onda, S. Nagata, B. Lee, R. J. Kreitman, and I. Pastan. 2000. Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity. Proc. Natl. Acad. Sci. USA 97: 8548-8553.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8548-8553
-
-
Tsutsumi, Y.1
Onda, M.2
Nagata, S.3
Lee, B.4
Kreitman, R.J.5
Pastan, I.6
-
12
-
-
49649091350
-
An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes
-
Onda, M., R. Beers, L. Xiang, S. Nagata, Q. C. Wang, and I. Pastan. 2008. An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes. Proc. Natl. Acad. Sci. USA 105: 11311-11316.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 11311-11316
-
-
Onda, M.1
Beers, R.2
Xiang, L.3
Nagata, S.4
Wang, Q.C.5
Pastan, I.6
-
13
-
-
79955007493
-
Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes
-
Onda, M., R. Beers, L. Xiang, B. Lee, J. E. Weldon, R. J. Kreitman, and I. Pastan. 2011. Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes. Proc. Natl. Acad. Sci. USA 108: 5742-5747.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 5742-5747
-
-
Onda, M.1
Beers, R.2
Xiang, L.3
Lee, B.4
Weldon, J.E.5
Kreitman, R.J.6
Pastan, I.7
-
14
-
-
84863957822
-
Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes
-
Liu, W., M. Onda, B. Lee, R. J. Kreitman, R. Hassan, L. Xiang, and I. Pastan. 2012. Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes. Proc. Natl. Acad. Sci. USA 109: 11782-11787.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 11782-11787
-
-
Liu, W.1
Onda, M.2
Lee, B.3
Kreitman, R.J.4
Hassan, R.5
Xiang, L.6
Pastan, I.7
-
15
-
-
79957890340
-
Pentostatin plus cyclophosphamide safely and effectively prevents immunotoxin immunogenicity in murine hosts
-
Mossoba, M. E., M. Onda, J. Taylor, P. R. Massey, S. Treadwell, E. Sharon, R. Hassan, I. Pastan, and D. H. Fowler. 2011. Pentostatin plus cyclophosphamide safely and effectively prevents immunotoxin immunogenicity in murine hosts. Clin. Cancer Res. 17: 3697-3705.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 3697-3705
-
-
Mossoba, M.E.1
Onda, M.2
Taylor, J.3
Massey, P.R.4
Treadwell, S.5
Sharon, E.6
Hassan, R.7
Pastan, I.8
Fowler, D.H.9
-
16
-
-
84887489815
-
The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: A systematic review of the literature with a meta-analysis
-
Garcês, S., J. Demengeot, and E. Benito-Garcia. 2013. The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis. Ann. Rheum. Dis. 72: 1947-1955.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 1947-1955
-
-
Garcês, S.1
Demengeot, J.2
Benito-Garcia, E.3
-
18
-
-
0036731485
-
Stats: Transcriptional control and biological impact
-
Levy, D. E., and J. E. Darnell, Jr. 2002. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3: 651-662.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr., J.E.2
-
19
-
-
0242468041
-
Regulation of JAK-STAT signalling in the immune system
-
Shuai, K., and B. Liu. 2003. Regulation of JAK-STAT signalling in the immune system. Nat. Rev. Immunol. 3: 900-911.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 900-911
-
-
Shuai, K.1
Liu, B.2
-
20
-
-
7244220019
-
JAK3 inhibition, a viable new modality of immunosuppression for solid organ transplants
-
Borie, D. C., J. J. O'Shea, and P. S. Changelian. 2004. JAK3 inhibition, a viable new modality of immunosuppression for solid organ transplants. Trends Mol. Med. 10: 532-541.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 532-541
-
-
Borie, D.C.1
O'Shea, J.J.2
Changelian, P.S.3
-
21
-
-
47249157224
-
Therapeutic targeting of Janus kinases
-
Pesu, M., A. Laurence, N. Kishore, S. H. Zwillich, G. Chan, and J. J. O'Shea. 2008. Therapeutic targeting of Janus kinases. Immunol. Rev. 223: 132-142.
-
(2008)
Immunol. Rev.
, vol.223
, pp. 132-142
-
-
Pesu, M.1
Laurence, A.2
Kishore, N.3
Zwillich, S.H.4
Chan, G.5
O'Shea, J.J.6
-
22
-
-
0242332186
-
Prevention of organ allograft rejection by a specific janus kinase 3 inhibitor
-
DOI 10.1126/science.1087061
-
Changelian, P. S., M. E. Flanagan, D. J. Ball, C. R. Kent, K. S. Magnuson, W. H. Martin, B. J. Rizzuti, P. S. Sawyer, B. D. Perry, W. H. Brissette, et al. 2003. Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science 302: 875-878. (Pubitemid 37339629)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 875-878
-
-
Changelian, P.S.1
Flanagan, M.E.2
Ball, D.J.3
Kent, C.R.4
Magnuson, K.S.5
Martin, W.H.6
Rizzuti, B.J.7
Sawyer, P.S.8
Perry, B.D.9
Brissette, W.H.10
McCurdy, S.P.11
Kudlacz, E.M.12
Conklyn, M.J.13
Elliott, E.A.14
Koslov, E.R.15
Fisher, M.B.16
Strelevitz, T.J.17
Yoon, K.18
Whipple, D.A.19
Sun, J.20
Munchhof, M.J.21
Doty, J.L.22
Casavant, J.M.23
Blumenkopf, T.A.24
Hines, M.25
Brown, M.F.26
Lillie, B.M.27
Subramanyam, C.28
Shang-Poa, C.29
Milici, A.J.30
Beckius, G.E.31
Moyer, J.D.32
Su, C.33
Woodworth, T.G.34
Gaweco, A.S.35
Beals, C.R.36
Littman, B.H.37
Fisher, D.A.38
Smith, J.F.39
Zagouras, P.40
Magna, H.A.41
Saltarelli, M.J.42
Johnson, K.S.43
Nelms, L.F.44
Des Etages, S.G.45
Hayes, L.S.46
Kawabata, T.T.47
Finco-Kent, D.48
Baker, D.L.49
Larson, M.50
Si, M.-S.51
Paniagua, R.52
Higgins, J.53
Holm, B.54
Reitz, B.55
Zhou, Y.-J.56
Morris, R.E.57
O'Shea, J.J.58
Borie, D.C.59
more..
-
23
-
-
62849094732
-
Selectivity and therapeutic inhibition of kinases: To be or not to be?
-
Ghoreschi, K., A. Laurence, and J. J. O'Shea. 2009. Selectivity and therapeutic inhibition of kinases: to be or not to be? Nat. Immunol. 10: 356-360.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 356-360
-
-
Ghoreschi, K.1
Laurence, A.2
O'Shea, J.J.3
-
24
-
-
79955027327
-
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)
-
Ghoreschi, K., M. I. Jesson, X. Li, J. L. Lee, S. Ghosh, J. W. Alsup, J. D. Warner, M. Tanaka, S. M. Steward-Tharp, M. Gadina, et al. 2011. Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550). J. Immunol. 186: 4234-4243.
-
(2011)
J. Immunol.
, vol.186
, pp. 4234-4243
-
-
Ghoreschi, K.1
Jesson, M.I.2
Li, X.3
Lee, J.L.4
Ghosh, S.5
Alsup, J.W.6
Warner, J.D.7
Tanaka, M.8
Steward-Tharp, S.M.9
Gadina, M.10
-
25
-
-
84864703156
-
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
-
ORAL Standard Investigators
-
van Vollenhoven, R. F., R. Fleischmann, S. Cohen, E. B. Lee, J. A. García Meijide, S. Wagner, S. Forejtova, S. H. Zwillich, D. Gruben, T. Koncz, et al; ORAL Standard Investigators. 2012. Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N. Engl. J. Med. 367: 508-519.
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 508-519
-
-
Van Vollenhoven, R.F.1
Fleischmann, R.2
Cohen, S.3
Lee, E.B.4
García Meijide, J.A.5
Wagner, S.6
Forejtova, S.7
Zwillich, S.H.8
Gruben, D.9
Koncz, T.10
-
26
-
-
84865592373
-
Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: A Phase 2b randomized placebo-controlled dose-ranging study
-
Papp, K. A., A. Menter, B. Strober, R. G. Langley, M. Buonanno, R. Wolk, P. Gupta, S. Krishnaswami, H. Tan, and J. A. Harness. 2012. Efficacy and safety of tofacitinib, an oral Janus kinase inhibitor, in the treatment of psoriasis: a Phase 2b randomized placebo-controlled dose-ranging study. Br. J. Dermatol. 167: 668-677.
-
(2012)
Br. J. Dermatol.
, vol.167
, pp. 668-677
-
-
Papp, K.A.1
Menter, A.2
Strober, B.3
Langley, R.G.4
Buonanno, M.5
Wolk, R.6
Gupta, P.7
Krishnaswami, S.8
Tan, H.9
Harness, J.A.10
-
27
-
-
58149092616
-
Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7Hpyrrolo[ 2,3-d]pyrimidin-4-yl)amino)piperidin-1- yl)-3-oxopropanenitrile (CP- 690,550)
-
Jiang, J. K., K. Ghoreschi, F. Deflorian, Z. Chen, M. Perreira, M. Pesu, J. Smith, D. T. Nguyen, E. H. Liu, W. Leister, et al. 2008. Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl- 3-(methyl(7Hpyrrolo[ 2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3- oxopropanenitrile (CP- 690,550). J. Med. Chem. 51: 8012-8018.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 8012-8018
-
-
Jiang, J.K.1
Ghoreschi, K.2
Deflorian, F.3
Chen, Z.4
Perreira, M.5
Pesu, M.6
Smith, J.7
Nguyen, D.T.8
Liu, E.H.9
Leister, W.10
-
28
-
-
0035394359
-
Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity
-
Onda, M., S. Nagata, Y. Tsutsumi, J. J. Vincent, Q. Wang, R. J. Kreitman, B. Lee, and I. Pastan. 2001. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity. Cancer Res. 61: 5070-5077. (Pubitemid 32681537)
-
(2001)
Cancer Research
, vol.61
, Issue.13
, pp. 5070-5077
-
-
Onda, M.1
Nagata, S.2
Tsutsumi, Y.3
Vincent, J.J.4
Wang, Q.-C.5
Kreitman, R.J.6
Lee, B.7
Pastan, I.8
-
29
-
-
23844438276
-
New monoclonal antibodies to mesothelin useful for immunohistochemistry, fluorescence-activated cell sorting, Western blotting, and ELISA
-
Onda, M., M. Willingham, S. Nagata, T. K. Bera, R. Beers, M. Ho, R. Hassan, R. J. Kreitman, and I. Pastan. 2005. New monoclonal antibodies to mesothelin useful for immunohistochemistry, fluorescence-activated cell sorting, Western blotting, and ELISA. Clin. Cancer Res. 11: 5840-5846.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 5840-5846
-
-
Onda, M.1
Willingham, M.2
Nagata, S.3
Bera, T.K.4
Beers, R.5
Ho, M.6
Hassan, R.7
Kreitman, R.J.8
Pastan, I.9
-
30
-
-
0018867518
-
Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymusindependent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency
-
Slack, J., G. P. Der-Balian, M. Nahm, and J. M. Davie. 1980. Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymusindependent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency. J. Exp. Med. 151: 853-862.
-
(1980)
J. Exp. Med.
, vol.151
, pp. 853-862
-
-
Slack, J.1
Der-Balian, G.P.2
Nahm, M.3
Davie, J.M.4
-
31
-
-
0742318929
-
The novel JAK-3 inhibitor CP- 690550 is a potent immunosuppressive agent in various murine models
-
Kudlacz, E., B. Perry, P. Sawyer, M. Conklyn, S. McCurdy, W. Brissette, M. Flanagan And, and P. Changelian. 2004. The novel JAK-3 inhibitor CP- 690550 is a potent immunosuppressive agent in various murine models. Am. J. Transplant. 4: 51-57.
-
(2004)
Am. J. Transplant.
, vol.4
, pp. 51-57
-
-
Kudlacz, E.1
Perry, B.2
Sawyer, P.3
Conklyn, M.4
McCurdy, S.5
Brissette, W.6
Flanagan, M.7
Changelian, P.8
-
32
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka, T., J. M. van Deursen, R. A. Tripp, W. E. Thierfelder, B. A. Witthuhn, A. P. McMickle, P. C. Doherty, G. C. Grosveld, and J. N. Ihle. 1995. Defective lymphoid development in mice lacking Jak3. Science 270: 800-802.
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
Van Deursen, J.M.2
Tripp, R.A.3
Thierfelder, W.E.4
Witthuhn, B.A.5
McMickle, A.P.6
Doherty, P.C.7
Grosveld, G.C.8
Ihle, J.N.9
-
33
-
-
0028799457
-
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
-
Thomis, D. C., C. B. Gurniak, E. Tivol, A. H. Sharpe, and L. J. Berg. 1995. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 270: 794-797.
-
(1995)
Science
, vol.270
, pp. 794-797
-
-
Thomis, D.C.1
Gurniak, C.B.2
Tivol, E.3
Sharpe, A.H.4
Berg, L.J.5
-
34
-
-
33644845081
-
Microenvironmental niches in the bone marrow required for B-cell development
-
Nagasawa, T. 2006. Microenvironmental niches in the bone marrow required for B-cell development. Nat. Rev. Immunol. 6: 107-116.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 107-116
-
-
Nagasawa, T.1
-
35
-
-
10944229170
-
Impaired B-1 and B-2 B cell development and atypical splenic B cell structures in IL-7 receptor-deficient mice
-
Erlandsson, L., S. Licence, F. Gaspal, S. Bell, P. Lane, A. E. Corcoran, and I. L. Mårtensson. 2004. Impaired B-1 and B-2 B cell development and atypical splenic B cell structures in IL-7 receptor-deficient mice. Eur. J. Immunol. 34: 3595-3603.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 3595-3603
-
-
Erlandsson, L.1
Licence, S.2
Gaspal, F.3
Bell, S.4
Lane, P.5
Corcoran, A.E.6
Mårtensson, I.L.7
-
36
-
-
18244386710
-
IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
-
Kikuchi, K., A. Y. Lai, C. L. Hsu, and M. Kondo. 2005. IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF. J. Exp. Med. 201: 1197-1203.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1197-1203
-
-
Kikuchi, K.1
Lai, A.Y.2
Hsu, C.L.3
Kondo, M.4
-
37
-
-
0033485342
-
Lymphoid-restricted development from multipotent candidate murine stem cells: Distinct and complimentary functions of the c-kit and flt3-ligands
-
Borge, O. J., J. Adolfsson, A. Mårtensson, I. L. Mårtensson, and S. E. Jacobsen. 1999. Lymphoid-restricted development from multipotent candidate murine stem cells: distinct and complimentary functions of the c-kit and flt3-ligands. Blood 94: 3781-3790.
-
(1999)
Blood
, vol.94
, pp. 3781-3790
-
-
Borge, O.J.1
Adolfsson, J.2
Mårtensson, A.3
Mårtensson, I.L.4
Jacobsen, S.E.5
-
38
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptordeficient mice
-
Peschon, J. J., P. J. Morrissey, K. H. Grabstein, F. J. Ramsdell, E. Maraskovsky, B. C. Gliniak, L. S. Park, S. F. Ziegler, D. E. Williams, C. B. Ware, et al. 1994. Early lymphocyte expansion is severely impaired in interleukin 7 receptordeficient mice. J. Exp. Med. 180: 1955-1960.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
Morrissey, P.J.2
Grabstein, K.H.3
Ramsdell, F.J.4
Maraskovsky, E.5
Gliniak, B.C.6
Park, L.S.7
Ziegler, S.F.8
Williams, D.E.9
Ware, C.B.10
-
39
-
-
33846632842
-
Interleukin-7 receptor expression: Intelligent design
-
Mazzucchelli, R., and S. K. Durum. 2007. Interleukin-7 receptor expression: intelligent design. Nat. Rev. Immunol. 7: 144-154.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 144-154
-
-
Mazzucchelli, R.1
Durum, S.K.2
-
40
-
-
84878946619
-
Tofacitinib: A review of its use in adult patients with rheumatoid arthritis
-
Scott, L. J. 2013. Tofacitinib: a review of its use in adult patients with rheumatoid arthritis. Drugs 73: 857-874.
-
(2013)
Drugs
, vol.73
, pp. 857-874
-
-
Scott, L.J.1
-
41
-
-
84872578731
-
A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity
-
Weldon, J. E., L. Xiang, J. Zhang, R. Beers, D. A. Walker, M. Onda, R. Hassan, and I. Pastan. 2013. A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity. Mol. Cancer Ther. 12: 48-57.
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 48-57
-
-
Weldon, J.E.1
Xiang, L.2
Zhang, J.3
Beers, R.4
Walker, D.A.5
Onda, M.6
Hassan, R.7
Pastan, I.8
-
42
-
-
79952269646
-
A phosphotyrosine proteomic screen identifies multiple tyrosine kinase signaling pathways aberrantly activated in malignant mesothelioma
-
Menges, C. W., Y. Chen, B. T. Mossman, J. Chernoff, A. T. Yeung, and J. R. Testa. 2010. A phosphotyrosine proteomic screen identifies multiple tyrosine kinase signaling pathways aberrantly activated in malignant mesothelioma. Genes Cancer 1: 493-505.
-
(2010)
Genes Cancer
, vol.1
, pp. 493-505
-
-
Menges, C.W.1
Chen, Y.2
Mossman, B.T.3
Chernoff, J.4
Yeung, A.T.5
Testa, J.R.6
-
43
-
-
0029414791
-
Role of the common cytokine receptor gamma chain in cytokine signaling and lymphoid development
-
Leonard, W. J., E. W. Shores, and P. E. Love. 1995. Role of the common cytokine receptor gamma chain in cytokine signaling and lymphoid development. Immunol. Rev. 148: 97-114.
-
(1995)
Immunol. Rev.
, vol.148
, pp. 97-114
-
-
Leonard, W.J.1
Shores, E.W.2
Love, P.E.3
-
44
-
-
0032903170
-
Immune response and airway reactivity in wild and IL-4 knockout mice exposed to latex allergens
-
Xia, J. Q., D. A. Rickaby, K. J. Kelly, H. Choi, C. A. Dawson, and V. P. Kurup. 1999. Immune response and airway reactivity in wild and IL-4 knockout mice exposed to latex allergens. Int. Arch. Allergy Immunol. 118: 23-29.
-
(1999)
Int. Arch. Allergy Immunol.
, vol.118
, pp. 23-29
-
-
Xia, J.Q.1
Rickaby, D.A.2
Kelly, K.J.3
Choi, H.4
Dawson, C.A.5
Kurup, V.P.6
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