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Volumn 1, Issue 5, 2010, Pages 493-505

A phosphotyrosine proteomic screen identifies multiple tyrosine kinase signaling pathways aberrantly activated in malignant mesothelioma

Author keywords

Asbestos; Coactivation; Mesothelioma; Proteomics; Tyrosine kinases

Indexed keywords

CORTACTIN; CRK ASSOCIATED SUBSTRATE PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; JANUS KINASE 1; PHOSPHOTYROSINE; PROTEIN KINASE FER; PROTEIN KINASE FYN; PROTEIN TYROSINE KINASE; PROTEOME; SCATTER FACTOR RECEPTOR; STAT1 PROTEIN;

EID: 79952269646     PISSN: 19476019     EISSN: 19476027     Source Type: Journal    
DOI: 10.1177/1947601910375273     Document Type: Article
Times cited : (44)

References (71)
  • 2
    • 33846327132 scopus 로고    scopus 로고
    • The use of chemotherapy in patients with advanced malignant pleural mesothelioma: A systematic review and practice guideline
    • Ellis P, Davies AM, Evans WK, Haynes AE, Lloyd NS. The use of chemotherapy in patients with advanced malignant pleural mesothelioma: a systematic review and practice guideline. J Thorac Oncol 2006;1:591-601.
    • (2006) J Thorac Oncol , vol.1 , pp. 591-601
    • Ellis, P.1    Davies, A.M.2    Evans, W.K.3    Haynes, A.E.4    Lloyd, N.S.5
  • 3
    • 33846099270 scopus 로고    scopus 로고
    • Pemetrexed alone or in combination with cisplatin in previously treated malignant pleural mesothelioma: Outcomes from a phase IIIB expanded access program
    • Janne PA, Wozniak AJ, Belani CP, et al. Pemetrexed alone or in combination with cisplatin in previously treated malignant pleural mesothelioma: outcomes from a phase IIIB expanded access program. J Thorac Oncol 2006;1:506-12.
    • (2006) J Thorac Oncol , vol.1 , pp. 506-512
    • Janne, P.A.1    Wozniak, A.J.2    Belani, C.P.3
  • 5
    • 0028818921 scopus 로고
    • High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas
    • Bianchi AB, Mitsunaga SI, Cheng JQ, et al. High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas. Proc Natl Acad Sci U S A 1995;92:10854-8.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10854-10858
    • Bianchi, A.B.1    Mitsunaga, S.I.2    Cheng, J.Q.3
  • 6
    • 0027960580 scopus 로고
    • P16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma
    • Cheng JQ, Jhanwar SC, Klein WM, et al. p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma. Cancer Res 1994;54:5547-51.
    • (1994) Cancer Res , vol.54 , pp. 5547-5551
    • Cheng, J.Q.1    Jhanwar, S.C.2    Klein, W.M.3
  • 8
    • 33748305989 scopus 로고    scopus 로고
    • High-resolution analysis of 9p loss in human cancer cells using single nucleotide polymorphism-based mapping arrays
    • Pei J, Kruger WD, Testa JR. High-resolution analysis of 9p loss in human cancer cells using single nucleotide polymorphism-based mapping arrays. Cancer Genet Cytogenet 2006;170:65-8.
    • (2006) Cancer Genet Cytogenet , vol.170 , pp. 65-68
    • Pei, J.1    Kruger, W.D.2    Testa, J.R.3
  • 9
    • 0028907620 scopus 로고
    • Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer
    • Sekido Y, Pass HI, Bader S, et al. Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. Cancer Res 1995;55:1227-31.
    • (1995) Cancer Res , vol.55 , pp. 1227-1231
    • Sekido, Y.1    Pass, H.I.2    Bader, S.3
  • 10
    • 24944522720 scopus 로고    scopus 로고
    • A mouse model recapitulating molecular features of human mesothelioma
    • Altomare DA, Vaslet CA, Skele KL, et al. A mouse model recapitulating molecular features of human mesothelioma. Cancer Res 2005;65:8090-5.
    • (2005) Cancer Res , vol.65 , pp. 8090-8095
    • Altomare, D.A.1    Vaslet, C.A.2    Skele, K.L.3
  • 11
    • 39849089040 scopus 로고    scopus 로고
    • A conditional mouse model for malignant mesothelioma
    • Jongsma J, van Montfort E, Vooijs M, et al. A conditional mouse model for malignant mesothelioma. Cancer Cell 2008;13:261-71.
    • (2008) Cancer Cell , vol.13 , pp. 261-271
    • Jongsma, J.1    van Montfort, E.2    Vooijs, M.3
  • 12
    • 62549148264 scopus 로고    scopus 로고
    • Activated TNF-α/NF-κB signaling via down-regulation of Fas-associated factor 1 in asbestosinduced mesotheliomas from Arf knockout mice
    • Altomare DA, Menges CW, Pei J, et al. Activated TNF-α/NF-κB signaling via down-regulation of Fas-associated factor 1 in asbestosinduced mesotheliomas from Arf knockout mice. Proc Natl Acad Sci U S A 2009;106:3420-5.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3420-3425
    • Altomare, D.A.1    Menges, C.W.2    Pei, J.3
  • 13
    • 24944539840 scopus 로고    scopus 로고
    • Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth
    • Altomare DA, You H, Xiao GH, et al. Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth. Oncogene 2005;24: 6080-9.
    • (2005) Oncogene , vol.24 , pp. 6080-6089
    • Altomare, D.A.1    You, H.2    Xiao, G.H.3
  • 14
    • 45149094559 scopus 로고    scopus 로고
    • Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids
    • Barbone D, Yang TM, Morgan JR, Gaudino G, Broaddus VC. Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids. J Biol Chem 2008;283:13021-30.
    • (2008) J Biol Chem , vol.283 , pp. 13021-13030
    • Barbone, D.1    Yang, T.M.2    Morgan, J.R.3    Gaudino, G.4    Broaddus, V.C.5
  • 15
    • 55249102222 scopus 로고    scopus 로고
    • MTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids
    • Wilson SM, Barbone D, Yang TM, et al. mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids. Am J Respir Cell Mol Biol 2008;39:576-83.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 576-583
    • Wilson, S.M.1    Barbone, D.2    Yang, T.M.3
  • 16
    • 0031932619 scopus 로고    scopus 로고
    • Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers
    • Pache JC, Janssen YM, Walsh ES, et al. Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers. Am J Pathol 1998;152:333-40.
    • (1998) Am J Pathol , vol.152 , pp. 333-340
    • Pache, J.C.1    Janssen, Y.M.2    Walsh, E.S.3
  • 17
    • 0030447748 scopus 로고    scopus 로고
    • Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogenactivated protein kinase cascade after phosphorylation of the epidermal growth factor receptor
    • Zanella CL, Posada J, Tritton TR, Mossman BT. Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogenactivated protein kinase cascade after phosphorylation of the epidermal growth factor receptor. Cancer Res 1996;56:5334-8.
    • (1996) Cancer Res , vol.56 , pp. 5334-5338
    • Zanella, C.L.1    Posada, J.2    Tritton, T.R.3    Mossman, B.T.4
  • 18
    • 33746278685 scopus 로고    scopus 로고
    • Phosphorylated extracellular signal-regulated kinases are significantly increased in malignant mesothelioma
    • de Melo M, Gerbase MW, Curran J, Pache JC. Phosphorylated extracellular signal-regulated kinases are significantly increased in malignant mesothelioma. J Histochem Cytochem 2006;54:855-61.
    • (2006) J Histochem Cytochem , vol.54 , pp. 855-861
    • de Melo, M.1    Gerbase, M.W.2    Curran, J.3    Pache, J.C.4
  • 19
    • 34247562351 scopus 로고    scopus 로고
    • Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma
    • Frey AB, Wali A, Pass H, Lonardo F. Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma. Histopathology 2007;50:720-6.
    • (2007) Histopathology , vol.50 , pp. 720-726
    • Frey, A.B.1    Wali, A.2    Pass, H.3    Lonardo, F.4
  • 20
    • 34347273808 scopus 로고    scopus 로고
    • Phase II study of erlotinib in patients with malignant pleural mesothelioma: A Southwest Oncology Group Study
    • Garland LL, Rankin C, Gandara DR, et al. Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study. J Clin Oncol 2007;25:2406-13.
    • (2007) J Clin Oncol , vol.25 , pp. 2406-2413
    • Garland, L.L.1    Rankin, C.2    Gandara, D.R.3
  • 21
    • 18844401069 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells
    • Vintman L, Nielsen S, Berner A, Reich R, Davidson B. Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells. Cancer 2005;103:2427-33.
    • (2005) Cancer , vol.103 , pp. 2427-2433
    • Vintman, L.1    Nielsen, S.2    Berner, A.3    Reich, R.4    Davidson, B.5
  • 22
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature 2001;411:355-65.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 23
    • 0037399412 scopus 로고    scopus 로고
    • Tyrosine kinases as targets in cancer therapy: Successes and failures
    • Traxler P. Tyrosine kinases as targets in cancer therapy: successes and failures. Expert Opin Ther Targets 2003;7:215-34.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 215-234
    • Traxler, P.1
  • 24
    • 33747769612 scopus 로고    scopus 로고
    • Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains
    • Dierck K, Machida K, Voigt A, et al. Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains. Nat Methods 2006;3:737-44.
    • (2006) Nat Methods , vol.3 , pp. 737-744
    • Dierck, K.1    Machida, K.2    Voigt, A.3
  • 25
    • 40649125574 scopus 로고    scopus 로고
    • Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells
    • Emaduddin M, Bicknell DC, Bodmer WF, Feller SM. Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci U S A 2008;105:2358-62.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2358-2362
    • Emaduddin, M.1    Bicknell, D.C.2    Bodmer, W.F.3    Feller, S.M.4
  • 26
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007;131:1190-203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3
  • 27
    • 35348822482 scopus 로고    scopus 로고
    • Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
    • Stommel JM, Kimmelman AC, Ying H, et al. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 2007;318:287-90.
    • (2007) Science , vol.318 , pp. 287-290
    • Stommel, J.M.1    Kimmelman, A.C.2    Ying, H.3
  • 28
    • 31544482729 scopus 로고    scopus 로고
    • Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma
    • Jagadeeswaran R, Ma PC, Seiwert TY, et al. Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma. Cancer Res 2006;66:352-61.
    • (2006) Cancer Res , vol.66 , pp. 352-361
    • Jagadeeswaran, R.1    Ma, P.C.2    Seiwert, T.Y.3
  • 29
    • 50249128105 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma
    • Okuda K, Sasaki H, Kawano O, et al. Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma. J Cancer Res Clin Oncol 2008;134:1105-11.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 1105-1111
    • Okuda, K.1    Sasaki, H.2    Kawano, O.3
  • 30
    • 0242285719 scopus 로고    scopus 로고
    • STAT proteins: From normal control of cellular events to tumorigenesis
    • Calo V, Migliavacca M, Bazan V, et al. STAT proteins: from normal control of cellular events to tumorigenesis. J Cell Physiol 2003;197:157-68.
    • (2003) J Cell Physiol , vol.197 , pp. 157-168
    • Calo, V.1    Migliavacca, M.2    Bazan, V.3
  • 31
    • 34547656272 scopus 로고    scopus 로고
    • Malignant mesothelioma: Global incidence and relationship with asbestos
    • Bianchi C, Bianchi T. Malignant mesothelioma: global incidence and relationship with asbestos. Ind Health 2007;45:379-87.
    • (2007) Ind Health , vol.45 , pp. 379-387
    • Bianchi, C.1    Bianchi, T.2
  • 32
    • 43049096401 scopus 로고    scopus 로고
    • STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice
    • Ernst M, Najdovska M, Grail D, et al. STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J Clin Invest 2008;118:1727-38.
    • (2008) J Clin Invest , vol.118 , pp. 1727-1738
    • Ernst, M.1    Najdovska, M.2    Grail, D.3
  • 33
    • 0031581070 scopus 로고    scopus 로고
    • C-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells
    • Cirri P, Chiarugi P, Marra F, et al. c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells. Biochem Biophys Res Commun 1997;239:493-7.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 493-497
    • Cirri, P.1    Chiarugi, P.2    Marra, F.3
  • 34
    • 57649089545 scopus 로고    scopus 로고
    • Radiosensitization by inhibiting STAT1 in renal cell carcinoma
    • Hui Z, Tretiakova M, Zhang Z, et al. Radiosensitization by inhibiting STAT1 in renal cell carcinoma. Int J Radiat Oncol Biol Phys 2009;73:288-95.
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 288-295
    • Hui, Z.1    Tretiakova, M.2    Zhang, Z.3
  • 35
    • 35148879113 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells
    • Khodarev NN, Minn AJ, Efimova EV, et al. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res 2007;67:9214-20.
    • (2007) Cancer Res , vol.67 , pp. 9214-9220
    • Khodarev, N.N.1    Minn, A.J.2    Efimova, E.V.3
  • 36
    • 33745727118 scopus 로고    scopus 로고
    • STAT1 acts as a tumor promoter for leukemia development
    • Kovacic B, Stoiber D, Moriggl R, et al. STAT1 acts as a tumor promoter for leukemia development. Cancer Cell 2006;10:77-87.
    • (2006) Cancer Cell , vol.10 , pp. 77-87
    • Kovacic, B.1    Stoiber, D.2    Moriggl, R.3
  • 37
    • 41849102742 scopus 로고    scopus 로고
    • EGFR and PDGFR differentially promote growth in malignant epithelioid mesothelioma of short and long term survivors
    • Kothmaier H, Quehenberger F, Halbwedl I, et al. EGFR and PDGFR differentially promote growth in malignant epithelioid mesothelioma of short and long term survivors. Thorax 2008;63:345-51.
    • (2008) Thorax , vol.63 , pp. 345-351
    • Kothmaier, H.1    Quehenberger, F.2    Halbwedl, I.3
  • 39
    • 17444374230 scopus 로고    scopus 로고
    • Src kinase regulation by phosphorylation and dephosphorylation
    • Roskoski R Jr. Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 2005;331:1-14.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 1-14
    • Roskoski Jr., R.1
  • 40
    • 0032509402 scopus 로고    scopus 로고
    • C-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells
    • Rahimi N, Hung W, Tremblay E, Saulnier R, Elliott B. c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells. J Biol Chem 1998;273:33714-21.
    • (1998) J Biol Chem , vol.273 , pp. 33714-33721
    • Rahimi, N.1    Hung, W.2    Tremblay, E.3    Saulnier, R.4    Elliott, B.5
  • 41
    • 33845713565 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells
    • Yamamoto N, Mammadova G, Song RX, Fukami Y, Sato K. Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells. J Cell Sci 2006;119:4623-33.
    • (2006) J Cell Sci , vol.119 , pp. 4623-4633
    • Yamamoto, N.1    Mammadova, G.2    Song, R.X.3    Fukami, Y.4    Sato, K.5
  • 42
    • 33847009160 scopus 로고    scopus 로고
    • SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines
    • Zhang J, Kalyankrishna S, Wislez M, et al. SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines. Am J Pathol 2007;170:366-76.
    • (2007) Am J Pathol , vol.170 , pp. 366-376
    • Zhang, J.1    Kalyankrishna, S.2    Wislez, M.3
  • 43
    • 33750076068 scopus 로고    scopus 로고
    • The role of Src in solid and hematologic malignancies: Development of new-generation Src inhibitors
    • Alvarez RH, Kantarjian HM, Cortes JE. The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors. Cancer 2006;107:1918-29.
    • (2006) Cancer , vol.107 , pp. 1918-1929
    • Alvarez, R.H.1    Kantarjian, H.M.2    Cortes, J.E.3
  • 44
    • 36949032298 scopus 로고    scopus 로고
    • SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy
    • Johnson FM, Gallick GE. SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy. Anticancer Agents Med Chem 2007;7:651-9.
    • (2007) Anticancer Agents Med Chem , vol.7 , pp. 651-659
    • Johnson, F.M.1    Gallick, G.E.2
  • 45
    • 33749003219 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma
    • Han LY, Landen CN, Trevino JG, et al. Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma. Cancer Res 2006;66:8633-9.
    • (2006) Cancer Res , vol.66 , pp. 8633-8639
    • Han, L.Y.1    Landen, C.N.2    Trevino, J.G.3
  • 46
    • 34249003640 scopus 로고    scopus 로고
    • Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells
    • Herynk MH, Zhang J, Parikh NU, Gallick GE. Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells. J Exp Ther Oncol 2007;6:205-17.
    • (2007) J Exp Ther Oncol , vol.6 , pp. 205-217
    • Herynk, M.H.1    Zhang, J.2    Parikh, N.U.3    Gallick, G.E.4
  • 47
    • 33745402375 scopus 로고    scopus 로고
    • Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells
    • Hiscox S, Morgan L, Green TP, Barrow D, Gee J, Nicholson RI. Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Breast Cancer Res Treat 2006;97:263-74.
    • (2006) Breast Cancer Res Treat , vol.97 , pp. 263-274
    • Hiscox, S.1    Morgan, L.2    Green, T.P.3    Barrow, D.4    Gee, J.5    Nicholson, R.I.6
  • 48
    • 6844259884 scopus 로고    scopus 로고
    • Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential
    • Mao W, Irby R, Coppola D, et al. Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential. Oncogene 1997;15:3083-90.
    • (1997) Oncogene , vol.15 , pp. 3083-3090
    • Mao, W.1    Irby, R.2    Coppola, D.3
  • 49
    • 33645072205 scopus 로고    scopus 로고
    • Treatment for advanced tumors: SRC reclaims center stage
    • Summy JM, Gallick GE. Treatment for advanced tumors: SRC reclaims center stage. Clin Cancer Res 2006;12:1398-401.
    • (2006) Clin Cancer Res , vol.12 , pp. 1398-1401
    • Summy, J.M.1    Gallick, G.E.2
  • 50
    • 33947356135 scopus 로고    scopus 로고
    • Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinibresistant or -intolerant chronic myeloid leukemia in blast crisis
    • Cortes J, Rousselot P, Kim DW, et al. Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinibresistant or -intolerant chronic myeloid leukemia in blast crisis. Blood 2007;109:3207-13.
    • (2007) Blood , vol.109 , pp. 3207-3213
    • Cortes, J.1    Rousselot, P.2    Kim, D.W.3
  • 51
    • 33846200681 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) is active in Philadelphia chromosome-positive chronic myelogenous leukemia after imatinib and nilotinib (AMN107) therapy failure
    • Quintas-Cardama A, Kantarjian H, Jones D, et al. Dasatinib (BMS-354825) is active in Philadelphia chromosome-positive chronic myelogenous leukemia after imatinib and nilotinib (AMN107) therapy failure. Blood 2007;109:497-9.
    • (2007) Blood , vol.109 , pp. 497-499
    • Quintas-Cardama, A.1    Kantarjian, H.2    Jones, D.3
  • 52
    • 34447316429 scopus 로고    scopus 로고
    • Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion
    • Tsao AS, He D, Saigal B, et al. Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion. Mol Cancer Ther 2007;6:1962-72.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1962-1972
    • Tsao, A.S.1    He, D.2    Saigal, B.3
  • 53
    • 38949107292 scopus 로고    scopus 로고
    • EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: Implications in targeting therapy
    • Fu YN, Yeh CL, Cheng HH, et al. EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy. Oncogene 2008;27:957-65.
    • (2008) Oncogene , vol.27 , pp. 957-965
    • Fu, Y.N.1    Yeh, C.L.2    Cheng, H.H.3
  • 54
    • 44849139232 scopus 로고    scopus 로고
    • Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells
    • Mueller KL, Hunter LA, Ethier SP, Boerner JL. Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells. Cancer Res 2008;68:3314-22.
    • (2008) Cancer Res , vol.68 , pp. 3314-3322
    • Mueller, K.L.1    Hunter, L.A.2    Ethier, S.P.3    Boerner, J.L.4
  • 55
    • 58149147368 scopus 로고    scopus 로고
    • Single-agent and combination therapeutic strategies to inhibit hepatocyte growth factor/MET signaling in cancer
    • Toschi L, Janne PA. Single-agent and combination therapeutic strategies to inhibit hepatocyte growth factor/MET signaling in cancer. Clin Cancer Res 2008;14:5941-6.
    • (2008) Clin Cancer Res , vol.14 , pp. 5941-5946
    • Toschi, L.1    Janne, P.A.2
  • 56
    • 34547676475 scopus 로고    scopus 로고
    • ErbB receptors: From oncogenes to targeted cancer therapies
    • Zhang H, Berezov A, Wang Q, et al. ErbB receptors: from oncogenes to targeted cancer therapies. J Clin Invest 2007;117:2051-8.
    • (2007) J Clin Invest , vol.117 , pp. 2051-2058
    • Zhang, H.1    Berezov, A.2    Wang, Q.3
  • 57
    • 0037105665 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma
    • Janne PA, Taffaro ML, Salgia R, Johnson BE. Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma. Cancer Res 2002;62:5242-7.
    • (2002) Cancer Res , vol.62 , pp. 5242-5247
    • Janne, P.A.1    Taffaro, M.L.2    Salgia, R.3    Johnson, B.E.4
  • 58
    • 28144442013 scopus 로고    scopus 로고
    • Inhibition of the met receptor in mesothelioma
    • Mukohara T, Civiello G, Davis IJ, et al. Inhibition of the met receptor in mesothelioma. Clin Cancer Res 2005;11:8122-30.
    • (2005) Clin Cancer Res , vol.11 , pp. 8122-8130
    • Mukohara, T.1    Civiello, G.2    Davis, I.J.3
  • 59
    • 0034808977 scopus 로고    scopus 로고
    • KGF and HGF are growth factors for mesothelial cells in pleural lavage fluid after intratracheal asbestos
    • Adamson IY, Bakowska J. KGF and HGF are growth factors for mesothelial cells in pleural lavage fluid after intratracheal asbestos. Exp Lung Res 2001;27:605-16.
    • (2001) Exp Lung Res , vol.27 , pp. 605-616
    • Adamson, I.Y.1    Bakowska, J.2
  • 60
    • 20144388693 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors and human malignant pleural mesothelioma: A first-step comparative translational study
    • Cesario A, Catassi A, Festi L, et al. Farnesyltransferase inhibitors and human malignant pleural mesothelioma: a first-step comparative translational study. Clin Cancer Res 2005;11:2026-37.
    • (2005) Clin Cancer Res , vol.11 , pp. 2026-2037
    • Cesario, A.1    Catassi, A.2    Festi, L.3
  • 61
    • 67650132370 scopus 로고    scopus 로고
    • Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells
    • Kawaguchi K, Murakami H, Taniguchi T, et al. Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells. Carcinogenesis 2009;30:1097-105.
    • (2009) Carcinogenesis , vol.30 , pp. 1097-1105
    • Kawaguchi, K.1    Murakami, H.2    Taniguchi, T.3
  • 62
    • 51449104064 scopus 로고    scopus 로고
    • Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer
    • Tang Z, Du R, Jiang S, et al. Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer. Br J Cancer 2008;99:911-22.
    • (2008) Br J Cancer , vol.99 , pp. 911-922
    • Tang, Z.1    Du, R.2    Jiang, S.3
  • 63
    • 56449089812 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations
    • Yano S, Wang W, Li Q, et al. Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. Cancer Res 2008;68:9479-87.
    • (2008) Cancer Res , vol.68 , pp. 9479-9487
    • Yano, S.1    Wang, W.2    Li, Q.3
  • 64
    • 34548278840 scopus 로고    scopus 로고
    • Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells
    • Bonine-Summers AR, Aakre ME, Brown KA, et al. Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells. Cancer Biol Ther 2007;6:561-70.
    • (2007) Cancer Biol Ther , vol.6 , pp. 561-570
    • Bonine-Summers, A.R.1    Aakre, M.E.2    Brown, K.A.3
  • 65
    • 34547881522 scopus 로고    scopus 로고
    • Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma
    • Huang PH, Mukasa A, Bonavia R, et al. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci U S A 2007;104:12867-72.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12867-12872
    • Huang, P.H.1    Mukasa, A.2    Bonavia, R.3
  • 66
    • 0034708826 scopus 로고    scopus 로고
    • Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells
    • Jo M, Stolz DB, Esplen JE, Dorko K, Michalopoulos GK, Strom SC. Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells. J Biol Chem 2000;275:8806-11.
    • (2000) J Biol Chem , vol.275 , pp. 8806-8811
    • Jo, M.1    Stolz, D.B.2    Esplen, J.E.3    Dorko, K.4    Michalopoulos, G.K.5    Strom, S.C.6
  • 67
    • 40749101512 scopus 로고    scopus 로고
    • Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor
    • Reznik TE, Sang Y, Ma Y, et al. Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor. Mol Cancer Res 2008;6:139-50.
    • (2008) Mol Cancer Res , vol.6 , pp. 139-150
    • Reznik, T.E.1    Sang, Y.2    Ma, Y.3
  • 68
    • 38649119730 scopus 로고    scopus 로고
    • Signaling networks assembled by oncogenic EGFR and c-Met
    • Guo A, Villen J, Kornhauser J, et al. Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 2008;105: 692-7.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 692-697
    • Guo, A.1    Villen, J.2    Kornhauser, J.3
  • 69
    • 0345352666 scopus 로고    scopus 로고
    • GDNF promotes tubulogenesis of GFRalpha1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase
    • Popsueva A, Poteryaev D, Arighi E, et al. GDNF promotes tubulogenesis of GFRalpha1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase. J Cell Biol 2003; 161:119-29.
    • (2003) J Cell Biol , vol.161 , pp. 119-129
    • Popsueva, A.1    Poteryaev, D.2    Arighi, E.3
  • 70
    • 0027853058 scopus 로고
    • Recurrent deletions of specific chromosomal sites in 1p, 3p, 6q, and 9p in human malignant mesothelioma
    • Taguchi T, Jhanwar SC, Siegfried JM, Keller SM, Testa JR. Recurrent deletions of specific chromosomal sites in 1p, 3p, 6q, and 9p in human malignant mesothelioma. Cancer Res 1993;53:4349-55.
    • (1993) Cancer Res , vol.53 , pp. 4349-4355
    • Taguchi, T.1    Jhanwar, S.C.2    Siegfried, J.M.3    Keller, S.M.4    Testa, J.R.5
  • 71
    • 65349134135 scopus 로고    scopus 로고
    • Proteomic analyses of pancreatic cyst fluids
    • Ke E, Patel BB, Liu T, et al. Proteomic analyses of pancreatic cyst fluids. Pancreas 2009;38:e33-42.
    • (2009) Pancreas , vol.38
    • Ke, E.1    Patel, B.B.2    Liu, T.3


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