-
1
-
-
67649844614
-
Polycystins and primary cilia: Primers for cell cycle progression
-
J Zhou Polycystins and primary cilia: primers for cell cycle progression Annu Rev Physiol 71 2009 83 113
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 83-113
-
-
Zhou, J.1
-
4
-
-
0036785149
-
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
-
BK Yoder, X Hou, and LM Guay-Woodford The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia J Am Soc Nephrol 13 2002 2508 2516
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2508-2516
-
-
Yoder, B.K.1
Hou, X.2
Guay-Woodford, L.M.3
-
6
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
SM Nauli, FJ Alenghat, Y Luo, E Williams, P Vassilev, X Li, AE Elia, W Lu, EM Brown, SJ Quinn, DE Ingber, and J Zhou Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells Nat Genet 33 2003 129 137
-
(2003)
Nat Genet
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
Alenghat, F.J.2
Luo, Y.3
Williams, E.4
Vassilev, P.5
Li, X.6
Elia, A.E.7
Lu, W.8
Brown, E.M.9
Quinn, S.J.10
Ingber, D.E.11
Zhou, J.12
-
7
-
-
0036707893
-
Genetics and pathogenesis of polycystic kidney disease
-
P Igarashi, and S Somlo Genetics and pathogenesis of polycystic kidney disease J Am Soc Nephrol 13 2002 2384 2398
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2384-2398
-
-
Igarashi, P.1
Somlo, S.2
-
8
-
-
34248166505
-
Polycystic kidney disease
-
P Igarashi, and S Somlo Polycystic kidney disease J Am Soc Nephrol 18 2007 1371 1373
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1371-1373
-
-
Igarashi, P.1
Somlo, S.2
-
9
-
-
44149123547
-
Structure and function of mammalian cilia
-
P Satir, and ST Christensen Structure and function of mammalian cilia Histochem Cell Biol 129 2008 687 693
-
(2008)
Histochem Cell Biol
, vol.129
, pp. 687-693
-
-
Satir, P.1
Christensen, S.T.2
-
10
-
-
29744470060
-
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
-
SH Low, S Vasanth, CH Larson, S Mukherjee, N Sharma, MT Kinter, ME Kane, T Obara, and T Weimbs Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease Dev Cell 10 2006 57 69
-
(2006)
Dev Cell
, vol.10
, pp. 57-69
-
-
Low, S.H.1
Vasanth, S.2
Larson, C.H.3
Mukherjee, S.4
Sharma, N.5
Kinter, M.T.6
Kane, M.E.7
Obara, T.8
Weimbs, T.9
-
11
-
-
0141703576
-
Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells
-
DH Grimm, Y Cai, V Chauvet, V Rajendran, R Zeltner, L Geng, ED Avner, W Sweeney, S Somlo, and MJ Caplan Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells J Biol Chem 278 2003 36786 36793
-
(2003)
J Biol Chem
, vol.278
, pp. 36786-36793
-
-
Grimm, D.H.1
Cai, Y.2
Chauvet, V.3
Rajendran, V.4
Zeltner, R.5
Geng, L.6
Avner, E.D.7
Sweeney, W.8
Somlo, S.9
Caplan, M.J.10
-
12
-
-
84920083456
-
The primary cilium calcium channels and their role in flow sensing
-
Epub 2014 Apr 26
-
Patel A: The primary cilium calcium channels and their role in flow sensing. Pflugers Arch - Eur J Physiol. doi:10.1007/s00424-014-1516-0. Epub 2014 Apr 26
-
Pflugers Arch - Eur J Physiol.
-
-
Patel, A.1
-
13
-
-
67649635952
-
Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia
-
MA Silverman, and MR Leroux Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia Trends Cell Biol 19 2009 306 316
-
(2009)
Trends Cell Biol
, vol.19
, pp. 306-316
-
-
Silverman, M.A.1
Leroux, M.R.2
-
15
-
-
77249103612
-
Molecular advances in autosomal dominant polycystic kidney disease
-
AR Gallagher, GG Germino, and S Somlo Molecular advances in autosomal dominant polycystic kidney disease Adv Chronic Kidney Dis 17 2010 118 130
-
(2010)
Adv Chronic Kidney Dis
, vol.17
, pp. 118-130
-
-
Gallagher, A.R.1
Germino, G.G.2
Somlo, S.3
-
16
-
-
0036667984
-
Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease
-
G Wu, X Tian, S Nishimura, GS Markowitz, V D'Agati, JH Park, L Yao, L Li, L Geng, H Zhao, W Edelmann, and S Somlo Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease Hum Mol Genet 11 2002 1845 1854
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1845-1854
-
-
Wu, G.1
Tian, X.2
Nishimura, S.3
Markowitz, G.S.4
D'Agati, V.5
Park, J.H.6
Yao, L.7
Li, L.8
Geng, L.9
Zhao, H.10
Edelmann, W.11
Somlo, S.12
-
17
-
-
0031035050
-
Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis
-
JL Brasier, and EP Henske Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis J Clin Invest 99 1997 194 199
-
(1997)
J Clin Invest
, vol.99
, pp. 194-199
-
-
Brasier, J.L.1
Henske, E.P.2
-
18
-
-
0030582668
-
The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type i
-
F Qian, TJ Watnick, LF Onuchic, and GG Germino The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I Cell 87 1996 979 987
-
(1996)
Cell
, vol.87
, pp. 979-987
-
-
Qian, F.1
Watnick, T.J.2
Onuchic, L.F.3
Germino, G.G.4
-
19
-
-
0035127256
-
Molecular genetics and pathogenesis of autosomal dominant polycystic kidney disease
-
MA Arnaout Molecular genetics and pathogenesis of autosomal dominant polycystic kidney disease Annu Rev Med 52 2001 93 123
-
(2001)
Annu Rev Med
, vol.52
, pp. 93-123
-
-
Arnaout, M.A.1
-
20
-
-
0035060409
-
A "two-hit" model of cystogenesis in autosomal dominant polycystic kidney disease?
-
Y Pei A "two-hit" model of cystogenesis in autosomal dominant polycystic kidney disease? Trends Mol Med 7 2001 151 156
-
(2001)
Trends Mol Med
, vol.7
, pp. 151-156
-
-
Pei, Y.1
-
21
-
-
36849037019
-
A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
-
K Piontek, LF Menezes, MA Garcia-Gonzalez, DL Huso, and GG Germino A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1 Nat Med 13 2007 1490 1495
-
(2007)
Nat Med
, vol.13
, pp. 1490-1495
-
-
Piontek, K.1
Menezes, L.F.2
Garcia-Gonzalez, M.A.3
Huso, D.L.4
Germino, G.G.5
-
22
-
-
0034639655
-
Genetic evidence for a trans-heterozygous model for cystogenesis in autosomal dominant polycystic kidney disease
-
M Koptides, R Mean, K Demetriou, A Pierides, and CC Deltas Genetic evidence for a trans-heterozygous model for cystogenesis in autosomal dominant polycystic kidney disease Hum Mol Genet 9 2000 447 452
-
(2000)
Hum Mol Genet
, vol.9
, pp. 447-452
-
-
Koptides, M.1
Mean, R.2
Demetriou, K.3
Pierides, A.4
Deltas, C.C.5
-
23
-
-
79959725455
-
A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation
-
SV Fedeles, X Tian, AR Gallagher, M Mitobe, S Nishio, SH Lee, Y Cai, L Geng, CM Crews, and S Somlo A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation Nat Genet 43 2011 639 647
-
(2011)
Nat Genet
, vol.43
, pp. 639-647
-
-
Fedeles, S.V.1
Tian, X.2
Gallagher, A.R.3
Mitobe, M.4
Nishio, S.5
Lee, S.H.6
Cai, Y.7
Geng, L.8
Crews, C.M.9
Somlo, S.10
-
24
-
-
0029069583
-
The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
-
J Hughes, CJ Ward, B Peral, R Aspinwall, K Clark, JL San Millan, V Gamble, and PC Harris The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains Nat Genet 10 1995 151 160
-
(1995)
Nat Genet
, vol.10
, pp. 151-160
-
-
Hughes, J.1
Ward, C.J.2
Peral, B.3
Aspinwall, R.4
Clark, K.5
San Millan, J.L.6
Gamble, V.7
Harris, P.C.8
-
25
-
-
77954596742
-
What is the role of somatic mutation in autosomal dominant polycystic kidney disease?
-
PC Harris What is the role of somatic mutation in autosomal dominant polycystic kidney disease? J Am Soc Nephrol 21 2010 1073 1076
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1073-1076
-
-
Harris, P.C.1
-
26
-
-
0034326319
-
Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells
-
MS Scheffers, P van der Bent, F Prins, L Spruit, MH Breuning, SV Litvinov, E de Heer, and DJ Peters Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells Hum Mol Genet 9 2000 2743 2750
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2743-2750
-
-
Scheffers, M.S.1
Van Der Bent, P.2
Prins, F.3
Spruit, L.4
Breuning, M.H.5
Litvinov, S.V.6
De Heer, E.7
Peters, D.J.8
-
27
-
-
0034095229
-
Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene
-
L Foggensteiner, AP Bevan, R Thomas, N Coleman, C Boulter, J Bradley, O Ibraghimov-Beskrovnaya, K Klinger, and R Sandford Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene J Am Soc Nephrol 11 2000 814 827
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 814-827
-
-
Foggensteiner, L.1
Bevan, A.P.2
Thomas, R.3
Coleman, N.4
Boulter, C.5
Bradley, J.6
Ibraghimov-Beskrovnaya, O.7
Klinger, K.8
Sandford, R.9
-
28
-
-
77952717195
-
Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity
-
ET Petri, A Celic, SD Kennedy, BE Ehrlich, TJ Boggon, and ME Hodsdon Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity Proc Natl Acad Sci U S A 107 2010 9176 9181
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 9176-9181
-
-
Petri, E.T.1
Celic, A.2
Kennedy, S.D.3
Ehrlich, B.E.4
Boggon, T.J.5
Hodsdon, M.E.6
-
29
-
-
0036122434
-
Polycystin-2 is an intracellular calcium release channel
-
P Koulen, Y Cai, L Geng, Y Maeda, S Nishimura, R Witzgall, BE Ehrlich, and S Somlo Polycystin-2 is an intracellular calcium release channel Nat Cell Biol 4 2002 191 197
-
(2002)
Nat Cell Biol
, vol.4
, pp. 191-197
-
-
Koulen, P.1
Cai, Y.2
Geng, L.3
Maeda, Y.4
Nishimura, S.5
Witzgall, R.6
Ehrlich, B.E.7
Somlo, S.8
-
30
-
-
33646764178
-
Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif
-
L Geng, D Okuhara, Z Yu, X Tian, Y Cai, S Shibazaki, and S Somlo Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif J Cell Sci 119 2006 1383 1395
-
(2006)
J Cell Sci
, vol.119
, pp. 1383-1395
-
-
Geng, L.1
Okuhara, D.2
Yu, Z.3
Tian, X.4
Cai, Y.5
Shibazaki, S.6
Somlo, S.7
-
31
-
-
57649114598
-
Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis
-
A Celic, ET Petri, B Demeler, BE Ehrlich, and TJ Boggon Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis J Biol Chem 283 2008 28305 28312
-
(2008)
J Biol Chem
, vol.283
, pp. 28305-28312
-
-
Celic, A.1
Petri, E.T.2
Demeler, B.3
Ehrlich, B.E.4
Boggon, T.J.5
-
32
-
-
84861217550
-
Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating
-
AS Celic, ET Petri, J Benbow, ME Hodsdon, BE Ehrlich, and TJ Boggon Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating J Biol Chem 287 2012 17232 17240
-
(2012)
J Biol Chem
, vol.287
, pp. 17232-17240
-
-
Celic, A.S.1
Petri, E.T.2
Benbow, J.3
Hodsdon, M.E.4
Ehrlich, B.E.5
Boggon, T.J.6
-
33
-
-
79960021509
-
Macromolecular assembly of polycystin-2 intracytosolic C-terminal domain
-
FM Ferreira, LC Oliveira, GG Germino, JN Onuchic, and LF Onuchic Macromolecular assembly of polycystin-2 intracytosolic C-terminal domain Proc Natl Acad Sci U S A 108 2011 9833 9838
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9833-9838
-
-
Ferreira, F.M.1
Oliveira, L.C.2
Germino, G.G.3
Onuchic, J.N.4
Onuchic, L.F.5
-
34
-
-
80052446941
-
Ciliopathies: An expanding disease spectrum
-
AM Waters, and PL Beales Ciliopathies: an expanding disease spectrum Pediatr Nephrol 26 2011 1039 1056
-
(2011)
Pediatr Nephrol
, vol.26
, pp. 1039-1056
-
-
Waters, A.M.1
Beales, P.L.2
-
35
-
-
80053004806
-
Spectrum of clinical diseases caused by disorders of primary cilia
-
SM Ware, MG Aygun, and F Hildebrandt Spectrum of clinical diseases caused by disorders of primary cilia Proc Am Thorac Soc 8 2011 444 450
-
(2011)
Proc Am Thorac Soc
, vol.8
, pp. 444-450
-
-
Ware, S.M.1
Aygun, M.G.2
Hildebrandt, F.3
-
36
-
-
0037513435
-
Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys
-
T Yamaguchi, S Nagao, DP Wallace, FA Belibi, BD Cowley, JC Pelling, and JJ Grantham Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys Kidney Int 63 2003 1983 1994
-
(2003)
Kidney Int
, vol.63
, pp. 1983-1994
-
-
Yamaguchi, T.1
Nagao, S.2
Wallace, D.P.3
Belibi, F.A.4
Cowley, B.D.5
Pelling, J.C.6
Grantham, J.J.7
-
37
-
-
0034126459
-
CAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway
-
T Yamaguchi, JC Pelling, NT Ramaswamy, JW Eppler, DP Wallace, S Nagao, LA Rome, LP Sullivan, and JJ Grantham cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway Kidney Int 57 2000 1460 1471
-
(2000)
Kidney Int
, vol.57
, pp. 1460-1471
-
-
Yamaguchi, T.1
Pelling, J.C.2
Ramaswamy, N.T.3
Eppler, J.W.4
Wallace, D.P.5
Nagao, S.6
Rome, L.A.7
Sullivan, L.P.8
Grantham, J.J.9
-
38
-
-
0035125616
-
Bilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney disease
-
Y Pei, AD Paterson, KR Wang, N He, D Hefferton, T Watnick, GG Germino, P Parfrey, S Somlo St, and P George-Hyslop Bilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney disease Am J Hum Genet 68 2001 355 363
-
(2001)
Am J Hum Genet
, vol.68
, pp. 355-363
-
-
Pei, Y.1
Paterson, A.D.2
Wang, K.R.3
He, N.4
Hefferton, D.5
Watnick, T.6
Germino, G.G.7
Parfrey, P.8
Somlo St, S.9
George-Hyslop, P.10
-
39
-
-
30344471203
-
Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1
-
ST Jiang, YY Chiou, E Wang, HK Lin, YT Lin, YC Chi, CK Wang, MJ Tang, and H Li Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1 Am J Pathol 168 2006 205 220
-
(2006)
Am J Pathol
, vol.168
, pp. 205-220
-
-
Jiang, S.T.1
Chiou, Y.Y.2
Wang, E.3
Lin, H.K.4
Lin, Y.T.5
Chi, Y.C.6
Wang, C.K.7
Tang, M.J.8
Li, H.9
-
40
-
-
19944406428
-
Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease
-
IS Lantinga-van Leeuwen, JG Dauwerse, HJ Baelde, WN Leonhard, A van de Wal, CJ Ward, S Verbeek, MC Deruiter, MH Breuning, E de Heer, and DJ Peters Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease Hum Mol Genet 13 2004 3069 3077
-
(2004)
Hum Mol Genet
, vol.13
, pp. 3069-3077
-
-
Lantinga-Van Leeuwen, I.S.1
Dauwerse, J.G.2
Baelde, H.J.3
Leonhard, W.N.4
Van De Wal, A.5
Ward, C.J.6
Verbeek, S.7
Deruiter, M.C.8
Breuning, M.H.9
De Heer, E.10
Peters, D.J.11
-
41
-
-
63949086532
-
Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease
-
S Rossetti, VJ Kubly, MB Consugar, K Hopp, S Roy, SW Horsley, D Chauveau, L Rees, TM Barratt, WG van't Hoff, P Niaudet, VE Torres, and PC Harris Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease Kidney Int 75 2009 848 855
-
(2009)
Kidney Int
, vol.75
, pp. 848-855
-
-
Rossetti, S.1
Kubly, V.J.2
Consugar, M.B.3
Hopp, K.4
Roy, S.5
Horsley, S.W.6
Chauveau, D.7
Rees, L.8
Barratt, T.M.9
Van'T Hoff, W.G.10
Niaudet, P.11
Torres, V.E.12
Harris, P.C.13
-
42
-
-
77958016655
-
Progressive renal distortion by multiple cysts in transgenic mice expressing artificial microRNAs against Pkd1
-
E Wang, HM Hsieh-Li, YY Chiou, YL Chien, HH Ho, HJ Chin, CK Wang, SC Liang, and ST Jiang Progressive renal distortion by multiple cysts in transgenic mice expressing artificial microRNAs against Pkd1 J Pathol 222 2010 238 248
-
(2010)
J Pathol
, vol.222
, pp. 238-248
-
-
Wang, E.1
Hsieh-Li, H.M.2
Chiou, Y.Y.3
Chien, Y.L.4
Ho, H.H.5
Chin, H.J.6
Wang, C.K.7
Liang, S.C.8
Jiang, S.T.9
-
43
-
-
84868613964
-
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity
-
K Hopp, CJ Ward, CJ Hommerding, SH Nasr, HF Tuan, VG Gainullin, S Rossetti, VE Torres, and PC Harris Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity J Clin Invest 122 2012 4257 4273
-
(2012)
J Clin Invest
, vol.122
, pp. 4257-4273
-
-
Hopp, K.1
Ward, C.J.2
Hommerding, C.J.3
Nasr, S.H.4
Tuan, H.F.5
Gainullin, V.G.6
Rossetti, S.7
Torres, V.E.8
Harris, P.C.9
-
44
-
-
0034326865
-
A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype
-
L Pritchard, JA Sloane-Stanley, JA Sharpe, R Aspinwall, W Lu, V Buckle, L Strmecki, D Walker, CJ Ward, CE Alpers, J Zhou, WG Wood, and PC Harris A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype Hum Mol Genet 9 2000 2617 2627
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2617-2627
-
-
Pritchard, L.1
Sloane-Stanley, J.A.2
Sharpe, J.A.3
Aspinwall, R.4
Lu, W.5
Buckle, V.6
Strmecki, L.7
Walker, D.8
Ward, C.J.9
Alpers, C.E.10
Zhou, J.11
Wood, W.G.12
Harris, P.C.13
-
45
-
-
84899977205
-
Polycystin-1: A master regulator of intersecting cystic pathways
-
SV Fedeles, AR Gallagher, and S Somlo Polycystin-1: a master regulator of intersecting cystic pathways Trends Mol Med 20 2014 251 260
-
(2014)
Trends Mol Med
, vol.20
, pp. 251-260
-
-
Fedeles, S.V.1
Gallagher, A.R.2
Somlo, S.3
-
46
-
-
63049116544
-
The vertebrate primary cilium in development, homeostasis, and disease
-
JM Gerdes, EE Davis, and N Katsanis The vertebrate primary cilium in development, homeostasis, and disease Cell 137 2009 32 45
-
(2009)
Cell
, vol.137
, pp. 32-45
-
-
Gerdes, J.M.1
Davis, E.E.2
Katsanis, N.3
-
47
-
-
56149097603
-
Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
-
JA Jonassen, J San Agustin, JA Follit, and GJ Pazour Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease J Cell Biol 183 2008 377 384
-
(2008)
J Cell Biol
, vol.183
, pp. 377-384
-
-
Jonassen, J.A.1
San Agustin, J.2
Follit, J.A.3
Pazour, G.J.4
-
48
-
-
0037019017
-
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease
-
GJ Pazour, JT San Agustin, JA Follit, JL Rosenbaum, and GB Witman Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease Curr Biol 12 2002 R378 R380
-
(2002)
Curr Biol
, vol.12
-
-
Pazour, G.J.1
San Agustin, J.T.2
Follit, J.A.3
Rosenbaum, J.L.4
Witman, G.B.5
-
49
-
-
35948965967
-
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella
-
K Huang, DR Diener, A Mitchell, GJ Pazour, GB Witman, and JL Rosenbaum Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella J Cell Biol 179 2007 501 514
-
(2007)
J Cell Biol
, vol.179
, pp. 501-514
-
-
Huang, K.1
Diener, D.R.2
Mitchell, A.3
Pazour, G.J.4
Witman, G.B.5
Rosenbaum, J.L.6
-
50
-
-
0037884961
-
Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
-
F Lin, T Hiesberger, K Cordes, AM Sinclair, LS Goldstein, S Somlo, and P Igarashi Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease Proc Natl Acad Sci U S A 100 2003 5286 5291
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5286-5291
-
-
Lin, F.1
Hiesberger, T.2
Cordes, K.3
Sinclair, A.M.4
Goldstein, L.S.5
Somlo, S.6
Igarashi, P.7
-
51
-
-
0034987372
-
The C. Elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms
-
CJ Haycraft, P Swoboda, PD Taulman, JH Thomas, and BK Yoder The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms Development 128 2001 1493 1505
-
(2001)
Development
, vol.128
, pp. 1493-1505
-
-
Haycraft, C.J.1
Swoboda, P.2
Taulman, P.D.3
Thomas, J.H.4
Yoder, B.K.5
-
52
-
-
34548490748
-
Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease
-
JR Davenport, AJ Watts, VC Roper, MJ Croyle, T van Groen, JM Wyss, TR Nagy, RA Kesterson, and BK Yoder Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease Curr Biol 17 2007 1586 1594
-
(2007)
Curr Biol
, vol.17
, pp. 1586-1594
-
-
Davenport, J.R.1
Watts, A.J.2
Roper, V.C.3
Croyle, M.J.4
Van Groen, T.5
Wyss, J.M.6
Nagy, T.R.7
Kesterson, R.A.8
Yoder, B.K.9
-
53
-
-
84883455352
-
Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
-
M Ma, X Tian, P Igarashi, GJ Pazour, and S Somlo Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease Nat Genet 45 2013 1004 1012
-
(2013)
Nat Genet
, vol.45
, pp. 1004-1012
-
-
Ma, M.1
Tian, X.2
Igarashi, P.3
Pazour, G.J.4
Somlo, S.5
-
54
-
-
84867336373
-
Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2
-
S Yoshiba, H Shiratori, IY Kuo, A Kawasumi, K Shinohara, S Nonaka, Y Asai, G Sasaki, JA Belo, H Sasaki, J Nakai, B Dworniczak, BE Ehrlich, P Pennekamp, and H Hamada Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2 Science 338 2012 226 231
-
(2012)
Science
, vol.338
, pp. 226-231
-
-
Yoshiba, S.1
Shiratori, H.2
Kuo, I.Y.3
Kawasumi, A.4
Shinohara, K.5
Nonaka, S.6
Asai, Y.7
Sasaki, G.8
Belo, J.A.9
Sasaki, H.10
Nakai, J.11
Dworniczak, B.12
Ehrlich, B.E.13
Pennekamp, P.14
Hamada, H.15
-
55
-
-
18744406718
-
FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
-
Y Tanaka, Y Okada, and N Hirokawa FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination Nature 435 2005 172 177
-
(2005)
Nature
, vol.435
, pp. 172-177
-
-
Tanaka, Y.1
Okada, Y.2
Hirokawa, N.3
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