Upregulation of sestrin-2 expression protects against endothelial toxicity of angiotensin II

Cell Biology and Toxicology

Volumn 30, Issue 3, 2014, Pages 147-156

  Yi, Lao ^a   Li, Feng ^a   Yong, Yuan ^a   Jianting, Dong ^a   Liting, Zhang ^a   Xuansheng, Huang ^a   Fei, Li ^a   Jiewen, Li ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Angiotensin II; JNK; Oxidative stress; Sestrin 2

Indexed keywords

ANGIOTENSIN II; CELL PROTEIN; CYTOPROTECTIVE AGENT; LACTATE DEHYDROGENASE; LUCIFERASE; MESSENGER RNA; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; SESTRIN 2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 4-HYDROXY-2-NONENAL; ALDEHYDE; NUCLEAR PROTEIN; SESN2 PROTEIN, HUMAN; SMALL INTERFERING RNA; VASOCONSTRICTOR AGENT;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UMBILICAL VEIN ENDOTHELIAL CELL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; SECRETION (PROCESS); SIGNAL TRANSDUCTION; UPREGULATION;

ALDEHYDES; ANGIOTENSIN II; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; L-LACTATE DEHYDROGENASE; MAP KINASE SIGNALING SYSTEM; NUCLEAR PROTEINS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; UP-REGULATION; VASOCONSTRICTOR AGENTS;

EID: 84903605631     PISSN: 07422091     EISSN: 15736822     Source Type: Journal    
DOI: 10.1007/s10565-014-9276-3     Document Type: Article

References (32)

1. Alves ES, Haidar AA, Quadros CD, Carvalho DS, Morgan D, Rocha MS, et al. Angiotensin II-induced JNK activation is mediated by NAD(P)H oxidase in isolated rat pancreatic islets. Regul Pept. 2012;175:1-6.
2. Bae SH, Sung SH, Oh SY, Lim JM, Lee SK, Park YN, et al. Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage. Cell Metab. 2013;17(1):73-84.
3. Brasier AR, Recinos 3rd A, Eledrisi MS. Vascular inflammation and the renin-angiotensin system. Arterioscler Thromb Vasc Biol. 2002;22:1257-66. (Pubitemid 34875734)
4. Brinkmann C, Brixius K. Peroxiredoxins and sports: new insights on the antioxidative defense. J Physiol Sci. 2013;63:1-5.
5. Budanov AV, Karin M. p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell. 2008;134:451-60.
6. Budanov AV, Shoshani T, Faerman A, Zelin E, Kamer I, Kalinski H, et al. Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability. Oncogene. 2002;21:6017-31.
7. Budanov AV, Sablina AA, Feinstein E, Koonin EV, Chumakov PM. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science. 2004;304:596-600. (Pubitemid 38541920)
8. Chen AF, Chen DD, Daiber A, Faraci FM, Li H, Rembold CM, et al. Free radical biology of the cardiovascular system. Clin Sci (Lond). 2012;123:73-91.
9. Dimmeler S, Rippmann V, Weiland U, Haendeler J, Zeiher AM. Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res. 1997;8:970-6. (Pubitemid 27514946)
10. Donnini S, Terzuoli E, Ziche M, Morbidelli L. Sulfhydryl angiotensin converting enzyme inhibitor promotes endothelial cell survival through nitric-oxide synthase, fibroblast growth factor-2, and telomerase cross-talk. J Pharmacol Exp Ther. 2010;332:776-84.
11. Eid AA, Lee DY, Roman LJ, Khazim K, Gorin Y. Sestrin 2 and AMPK connect hyperglycemia to Nox4-dependent endothelial nitric oxide synthase uncoupling and matrix protein expression. Mol Cell Biol. 2013;33:3439-60.
12. Hu B, Jarzynka MJ, Guo P, Imanishi Y, Schlaepfer DD, Cheng SY. Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res. 2006;66:775-83. (Pubitemid 43165942)
13. Kallenborn-Gerhardt W, Lu R, Syhr KM, Heidler J, vonMelchner H, Geisslinger G, et al. Antioxidant activity of sestrin 2 controls neuropathic pain after peripheral nerve injury. Antioxid Redox Signal. 2013;19(17):2013-23.
14. Lee JH, Bodmer R, Bier E, Karin M. Sestrins at the crossroad between stress and aging. Aging (Albany NY). 2010;2:369-74.
15. Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, et al. Maintenance of metabolic homeostasis by sestrin2 and sestrin3. Cell Metab. 2012a;16:311-21.
16. Lee R, Channon KM, Antoniades C. Therapeutic strategies targeting endothelial function in humans: clinical implications. Curr Vasc Pharmacol. 2012b;10:77-93.
17. Lin CP, Lin FY, Huang PH, Chen YL, Chen WC, Chen HY, et al. Endothelial progenitor cell dysfunction in cardiovascular diseases: role of reactive oxygen species and inflammation. Biomed Res Int. 2013;2013:845037.
18. Mai J, Qiu Q, Lin YQ, Luo NS, Zhang HF, Wen ZZ, Wang JF, Yangxin C. Angiotensin II-derived reactive oxygen species promote angiogenesis in human late endothelial progenitor cells through Heme oxygenase-1 via ERK1/2 and AKT/PI3K pathways. Inflammation. 2014.
19. Rosenbaugh EG, Savalia KK, Manickam DS, Zimmerman MC. Antioxidant-based therapies for angiotensin II-associated cardiovascular diseases. Am J Physiol Regul Integr Comp Physiol. 2013;304:R917-28.
20. Sanchis-Gomar F. Sestrins: novel antioxidant and AMPK-modulating functions regulated by exercise? J Cell Physiol. 2013;228(8):1647-50.
21. Sata M, Fukuda D. Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis. J Med Investig. 2010;57:12-25.
22. Shatat MA, Tian H, Zhang R, Tandon G, Hale A, Fritz JS, Zhou G, Martínez-González J, Rodríguez C, Champion HC, Jain MK, HamikA. Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension. Am J Respir Cell Mol Biol. 2013 Oct 24.
23. Sheng B, Gong K, Niu Y, Liu L, Yan Y, Lu G, et al. Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: implications for the treatment of Alzheimer's disease. Free Radic Biol Med. 2009;46:1362-75.
24. Shi H, Sheng B, Zhang F, Wu C, Zhang R, Zhu J, et al. Kruppel-like factor 2 protects against ischemic stroke by regulating endothelial blood brain barrier function. Am J Physiol Heart Circ Physiol. 2013;304:H796-805.
25. Shin BY, Jin SH, Cho IJ, Ki SH. Nrf2-ARE pathway regulates induction of Sestrin-2 expression. Free Radic Biol Med. 2012;53(4):834-41.
26. Wang ZY, Sato H, Kusam S, Sehra S, Toney LM, Dent AL. Regulation of IL-10 gene expression in Th2 cells by Jun proteins. J Immunol. 2005;174:2098-105. (Pubitemid 40223953)
27. Wolf G. Role of reactive oxygen species in angiotensin II-mediated renal growth, differentiation, and apoptosis. Antioxid Redox Signal. 2005;7:1337-45. (Pubitemid 41232531)
28. Xue H, Zhou L, Yuan P, Wang Z, Ni J, Yao T, et al. Counter-action between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells. Regul Pept. 2012;177:12-20.
29. Yang D, Zhang M, Huang X, Fang F, Chen B, Wang S, et al. Protection of retinal vasculature by losartan against apoptosis and vasculopathy in rats with spontaneous hypertension. J Hypertens. 2010;28:510-9.
30. Zhang XY, Wu XQ, Deng R, Sun T, Feng GK, Zhu XF. Upregulation of sestrin 2 expression via JNK pathway activation contributes to autophagy induction in cancer cells. Cell Signal. 2013;25(1):150-8.
31. Zhou MS, Schulman IH, Chadipiralla K, Raij L. Role of c-Jun N-terminal kinase in the regulation of vascular tone. J Cardiovasc Pharmacol Ther. 2010;15:78-83.
32. Zhou G, Hamik A, Nayak L, Tian H, Shi H, Lu Y, et al. Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice. J Clin Invest. 2012;122:4727-31.