Pro- and anti-inflammatory cytokine gene expression in rat sciatic nerve chronic constriction injury model of neuropathic pain

Experimental Neurology

Volumn 169, Issue 2, 2001, Pages 386-391

  Okamoto, Kunihisa ^a   Martin, David P ^a   Schmelzer, James D ^a   Mitsui, Yoshiyuki ^a   Low, Phillip A ^a  

^a MAYO CLINIC   (United States)

Author keywords

Cytokine; Hyperalgesia; Interleukin; Ischemia; Pain; Rat; TNF

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR;

ANIMAL BEHAVIOR; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HYPERALGESIA; INFLAMMATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PAIN; PERIPHERAL NERVE INJURY; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE;

EID: 0034994231     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2001.7677     Document Type: Article

References (23)

1. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
2. Macrophage deactivation by interleukin 10
3. Interleukin-6 production by Schwann cells and induction in sciatic nerve injury
4. Role of peri-axonal inflammation in the development of thermal hyperalgesia and guarding behavior in a rat model of neuropathic pain
5. Microvascular responses to cerebral ischemia/inflammation
6. Trends and future developments in the pharmacological treatment of acute ischaemic stroke
7. IL-10 inhibits cytokine production by activated macrophages
8. Anticytokine therapy in rheumatoid arthritis
9. A system to measure thermal nociception
10. Serial determination of tumor necrosis factoralpha content in rat sciatic nerve after chronic constriction injury
11. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
12. Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve
13. Possible chemical contribution from chromic gut sutures produces disorders of pain sensation like those seen in man
14. The expression of proinflammatory cytokine mRNA in the sciatic-tibial nerve of ischemia-reperfusion injury
15. Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10
16. Interleukin-1 activity in lesioned peripheral nerve
17. Chronic constriction model of rat sciatic nerve: Nerve blood flow, morphologic and biochemical alterations
18. The effect of thalidomide treatment on vascular pathology and hyperalgesia caused by chronic constriction injury of rat nerve
19. Extra-territorial pain in rats with a peripheral mononeuropathy: Mechano-allodynia in the territory of an uninjured nerve
20. Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression
21. Endoneurial injection of TNF-α produces neuropathic pain behaviors
22. Changes in plasma cytokines associated with peripheral nerve injury
23. Peripheral neuropeptide plasticity in a quadruple ligature model of painful neuropathy