Curcumin inhibits the invasion of thyroid cancer cells via down-regulation of PI3K/Akt signaling pathway

Gene

Volumn 546, Issue 2, 2014, Pages 226-232

  Xu, XiaoBo ^a   Qin, Jian ^a   Liu, WenYong ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Curcumin; FTC133; PI3K Akt signaling pathways; Thyroid cancer

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CURCUMIN; CYCLOOXYGENASE 2; INTERSTITIAL COLLAGENASE; MATRILYSIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FTC133 CELL LINE; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THYROID CANCER; THYROID CANCER CELL LINE; WESTERN BLOTTING; PROTEIN PHOSPHORYLATION; TUMOR INVASION;

CURCUMIN; FTC133; PI3K/AKT SIGNALING PATHWAYS; THYROID CANCER;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CURCUMIN; CYCLOOXYGENASE 2; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 7; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; THYROID NEOPLASMS;

EID: 84903537415     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.06.006     Document Type: Article

References (42)

1. Bianchini F., D'Alessio S., Fibbi G., Del R.M., Calorini L. Cytokine-dependent invasiveness in B16 murine melanoma cells: role of uPA system and MMP-9. Oncol. Rep. 2006, 15:709-714.
2. Burgess J.R. Temporal trends for thyroid carcinoma in Australia: an increasing incidence of papillary thyroid carcinoma (1982-1997). Thyroid 2002, 12(2):141-149.
3. Cole G.W., Alleva A.M., Zuo J.T., Sehgal S.S., Yeow W.S., Schrump D.S., Nguyen D.M., et al. Suppression of pro-metastasis phenotypes expression in malignant pleural mesothelioma by the PI3K inhibitor LY294002 or the MEK inhibitor UO126. Anticancer Res. 2006, 26:809-821.
4. Dorai T., Cao Y.C., Dorai B., Buttyan R., Katz A.E. Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate 2001, 47:293-303.
5. Ellerbroek S.M., Fishman D.A., Kearns A.S., Bafetti L.M., Stack M.S. Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through beta1 integrin. Cancer Res. 1999, 59:1635-1641.
6. Friedl P., Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 2003, 3:362-374.
7. Gress T.M., Mur̈ ller-Pillasch F., Lerch M.M., Friess H., Bur̈ chler M., Adler G. Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int. J. Cancer 1995, 62:407-413.
8. Guatam S.C., Xu Y.X., Pindolia K.R., Janakiraman N., Chapman R.A. Nonselective inhibition of proliferation of transformed and transformed cells by anticancer agent curcumin (diferuloylmethane). Biochem. Pharmacol. 1998, 55:1333-1337.
9. Hansen M.B., Nielsen S.E., Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods 1989, 119:203-210.
10. Haselkorn T., Bernstein L., Preston-Martin S., Cozen W., Mack W.J. Descriptive epidemiology of thyroid cancer in Los Angeles County, 1972-1995. Cancer Causes Control 2000, 11(2):163-170.
11. Henson E.S., Gibson S.B. Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy. Cell. Signal. 2006, 18:2089-2097.
12. Hong J.M., Park C.S., Nam-Goong I.S., Kim Y.S., Lee J.C., Han M.W., Choi J.I., Kim Y.I., Kim E.S. Curcumin enhances docetaxel-induced apoptosis of 8505C anaplastic thyroid carcinoma cells. Endocrinol. Metab. (Seoul) 2014, 29(1):54-61.
13. Hsu H.F., Wu Y.C., Chen L.C., Houng J.Y. Induction of apoptosis of A549 lung cancer cell line by dehydrocostus lactone isolated from Glossogyne tenuifolia. J. Food Drug Anal. 2009, 17:107-115.
14. Huang M.T., Lysz T., Ferraro T., Abidi T.F., Laskin J.D., Conney A.H. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 1991, 51:813-819.
15. Huang C.Z., Huang W.Z., Zhang G., Tang D.L. In vivo study on the effects of curcumin on the expression profiles of anti-tumour genes (VEGF, CyclinD1 and CDK4) in liver of rats injected with DEN. Mol. Biol. Rep. 2013, 40(10):5825-5831.
16. Inoue K., Nomura C., Ito S., Nagatsu A., Hino T., Oka H. Purification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin by high-speed countercurrent chromatography. J. Agric. Food Chem. 2008, 56:9328-9336.
17. Itoh Y., Nagase H. Matrix metalloproteinases in cancer. Essays Biochem. 2002, 38:21-36.
18. Kamesaki H. Mechanisms involved in chemotherapy-induced apoptosis and their implications in cancer chemotherapy. Int. J. Hematol. 1998, 68:29-43.
19. Kawamori T., Lubet R., Steele V.E., Kelloff G.J., Kaskey R.B., Rao C.V., Reddy B.S. Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res. 1999, 59:597-601.
20. Kuzma L., Wysokinska H., Rozalski M., Krajewska U., Kisiel W. An unusual taxodione derivative from hairy roots of Salvia austriaca. Fitoterapia 2012, 83:770-773.
21. Li T.-J., Cui J. COX-2, MMP-7 expression in oral lichen planus and oral squamous cell carcinoma. Asian Pac. J. Trop. Med. 2013, 6:640-643.
22. Liau S.S., Jazag A., Whang E.E. HMGA1 is a determinant of cellular invasiveness and in vivo metastatic potential in pancreatic adenocarcinoma. Cancer Res. 2006, 66:11613-11622.
23. Liu S., Semenciw R., Ugnat A.M., Mao Y. Increasing thyroid cancer incidence in Canada, 1970-1996: time trends and age-period-cohort effects. Br. J. Cancer 2001, 85(9):1335-1339.
24. Matsuoka H., Tsubaki M., Yamazoe Y., Ogaki M., Satou T., Itoh T., et al. Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways. Exp. Cell Res. 2009, 315:2022-2032.
25. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
26. Nagata M., Fujita H., Ida H., Hoshina H., Inoue T., Seki Y., et al. Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis. Int. J. Cancer 2003, 106:683-689.
27. Otani Y., Okazaki I., Arai M., Kameyama K., Wada N., Maruyama K., et al. Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers. J. Gastroenterol. 1994, 29:391-397.
28. Park C.H., Hahm E.R., Park S., Kim H.K., Yang C.H. The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling. FEBS Lett. 2005, 579:2965-2971.
29. Pillai G.S., Srivastava A.S., Hassanein T.I., Chauhan D.P., Carrier E. Induction of apoptosis in human lung cancer cells by curcumin. Cancer Lett. 2004, 208:163-170.
30. Queiroga F.L., Pires I., Parente M., Gregório H., Lopes C.S. COX-2 over-expression correlates with VEGF and tumour angiogenesis in canine mammary cancer. Vet. J. 2011, 189:77-82.
31. Rao C.V., Rivenson A., Simi B., Reddy B.S. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res. 1995, 55:259-266.
32. Ruby A.J., Kuttan G., Babu K.D., Rajasekharan K.N., Kuttan R. Anti-tumour and antioxidant activity of natural curcuminoids. Cancer Lett. 1995, 94:79-83.
33. Saha S., Adhikary A., Bhattacharyya P., Das T., Sa G. Death by design: where curcumin sensitizes drug-resistant tumours. Anticancer Res. 2012, 32:2567-2584.
34. Sipos J.A., Mazzaferri E.L. Thyroid cancer epidemiology and prognostic variables. Clin. Oncol. 2010, 22:395-404.
35. Takeharu H., Yasukawa K., Inouye K. Thermodynamic analysis of ionizable groups involved in the catalytic mechanism of human matrix metalloproteinase 7 (MMP-7). Biochim. Biophys. Acta Protein Proteomics 2011, 1814:1940-1946.
36. Verma S.P., Salamone E., Goldin B. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. Biochem. Biophys. Res. Commun. 1997, 233:692-696.
37. Vincenti M.P., White L.A., Schroen D.J., Benbow U., Brinckerhoff C.E. Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): mechanisms that control enzyme activity, transcription, and mRNA stability. Crit. Rev. Eukaryot. Gene Expr. 1996, 6:391-411.
38. Wang L., Ling Y., Chen Y., Li C.L., Feng F., You Q.D., Lu N., Guo Q.L. Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells. Cancer Lett. 2010, 297:42-48.
39. Yang S.F., Chen M.K., Hsieh Y.S., Yang J.S., Zavras A.I., Hsieh Y.H., Su S.C., Kao T.Y., Chen P.N., Chu S.C. Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases. Food Chem. Toxicol. 2010, 48:1052-1058.
40. Yeh M.W., Rougier J.P., Park J.W., Duh Q.Y., Wong M., Werb Z., et al. Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A. Endocr. Relat. Cancer 2006, 13:1173-1183.
41. Zhang C.Y., Zhang L., Yu H.X., Bao J.D., Sun Z., Lu R.R. Curcumin inhibits invasion and metastasis in K1 papillary thyroid cancer cells. Food Chem. 2013, 139(1-4):1021-1028.
42. Zhang C.Y., Zhang L., Yu H.X., Bao J.D., Lu R.R. Curcumin inhibits the metastasis of K1 papillary thyroid cancer cells via modulating E-cadherin and matrix metalloproteinase-9 expression. Biotechnol. Lett. 2013, 35(7):995-1000.