Induction of apoptosis of A549 lung cancer cell line by dehydrocostus lactone isolated from Glossogyne Tenuifolia

Journal of Food and Drug Analysis

Volumn 17, Issue 2, 2009, Pages 107-115

  Hsu, Hsia Fen ^a   Wu, Yang Chang ^a   Chen, Let Chin ^b   Houng, Jer Yiing ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Cytotoxicity; Dehydrocostus lactone; Glossogyne tenuifolia; Lung cancer cell line A549; Mokko lactone

Indexed keywords

CASPASE 3; CASPASE 9; DEHYDROCOSTUS LACTONE; DOXORUBICIN; MOKKO LACTONE; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOMETRY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVATION; GLOSSOGYNE TENUIFOLIA; HERB; HUMAN; HUMAN CELL; STRUCTURE ANALYSIS;

GLOSSOGYNE; GLOSSOGYNE TENUIFOLIA;

EID: 67649790694     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Jin, M., Lee, H. J., Ryu, J. H. and Chung, K. S. 2000. Inhibition of LPS-induced NO production and NF-kappa B activation by a sesquiterpene from Saussurea lappa. Arch. Pharm. Res. 23: 54-58.
2. Lee, H. J., Kim, N. Y., Jang, M. K., Son, H. J., Kim, K. M., Sohn, D. H., Lee, S. H. and Ryu, J. H. 1999. A sesquiterpene, dehydrocostus lactone, inhibits the expression of inducible nitric oxide synthase and TNF-alpha in LPS-activated macrophages. Planta Med. 65: 104-108. (Pubitemid 29138139)
3. Oh, G. S., Pae, H. O., Chung, H. T., Kwon, J. W., Lee, J. H., Kwon, T. O., Kwon, S. Y., Chon, B. H. and Yun, Y. G. 2004. Dehydrocostus lactone enhances tumor necrosis factor-alpha-induced apoptosis of human leukemia HL-60 cells. Immunopharmacol. Immunotoxicol. 26: 163-175.
4. Yun, Y. G., Oh, H., Oh, G. S., Pae, H. O., Choi, B. M., Kwon, J. W., Kwon, T. O., Jang, S. I. and Chung, H. T. 2004. In vitro cytotoxicity of mokko lactone in human leukemia HL-60 cells: induction of apoptotic cell death by mitochondrial membrane potential collapse. Immunopharmacol. Immunotoxicol. 26: 343-353.
5. Zhang, S., Won, Y. K., Ong, C. N. and Shen, H. M. 2005. Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms. Curr. Med. Chem. Anticancer Agents 5: 239-249.
6. Chen, H. C., Chou, C. K., Lee, S. D., Wang, J. C. and Yeh, S. F. 1995. Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells. Antiviral Res. 27: 99-109.
7. Hwang, D. R., Wu, Y. S., Chang, C. W., Lien, T. W., Chen, W. C., Tan, U. K., Hsu, J. T. and Hsieh, H. P. 2005. Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system. Bioorg. Med. Chem.14: 83-91.
8. Penissi, A. B., Rudolph, M. I. and Piezzi, R. S. 2003. Role of mast cells in gastrointestinal mucosal defense. Biocell 27: 163-172. (Pubitemid 37087150)
9. Sriram, D., Rao, V. S., Chandrasekhara, K. V. and Yogeeswari, P. 2004. Progress in the research of artemisinin and its analogues as antimalarials: an update. Nat. Prod. Res. 18: 503-527.
10. Kwon, H. J., 2003. Chemical genomics-based target identification and validation of anti-angiogenic agents. Curr. Med. Chem. 10: 717-736.
11. Luna-Herrera, J., Costa, M. C., Gonzalez, H. G., Rodrigues, A. I. and Castilho, P. C. 2007. Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp. J. Antimicrob. Chemother. 59: 548-552.
12. Matsuda, H., Shimoda, H., Uemura, T. and Yoshikawa, M. 1999. Preventive effect of sesquiterpenes from bay leaf on blood ethanol elevation in ethanol-loaded rat: structure requirement and suppression of gastric emptying. Bioorg. Med. Chem. Lett. 9: 2647-2652.
13. Gu, J. Q., Gills, J .J., Park, B. J., Mata-Greenwood, E., Hawthorne, M. E., Axelrod, F., Chavez, P. I., Fong, H. H., Mehta, R. G., Pezzuto, J. M. and Kinghorn, A. D. 2002. Sesquiterpenoids from Tithonia diversfolia with potential cancer chemopreventive activity. J. Nat. Prod. 65: 532-536.
14. Wu, M. J., Wang, L., Ding, H. Y., Weng, C. Y. and Yen, J. H. 2004. Glossogyne tenufolia acts to inhibit inflammatory mediator production in a macrophage cell line by downregulating LPS-induced NF-kappa B. J. Biomed. Sci. 11: 186-199.
15. Wu, M. J., Weng, C. Y., Ding, H. Y. and Wu, P. J. 2005. Anti-inflammatory and antiviral effects of Glossogyne tenufolia. Life Sci. 76: 1135-1146. (Pubitemid 40037535)
16. Hsu, H. F., Houng, J. Y., Chang, C. L., Wu, C. C., Chang, F. R. and Wu, Y. C. 2005. Antioxidant activity, cytotoxicity, and DNA information of Glossogyne tenujfolia. J. Agric. Food Chem. 53: 6117-6125.
17. Noble, J. R., Willetts, K. B., Mercer, W. E. and Reddel, R. R. 1992. Effects of exogenous wild-type p53 on a human lung carcinoma cell line with endogenous wild-type p53. Exp. Cell Res. 203: 297-304.
18. Bando, H., Toi, M., Kitada, K. and Koike, M. 2003. Genes commonly upregulated by hypoxia in human breast cancer cells MCF-7 and MDA-MB-231. Biomed. Pharmacother. 57: 333-340.
19. Zhang, J., Li, Q., Nguyen, T. D., Tremblay, T. L., Stone, E., To, R., Kelly, J. and MacKenzie, C. R. 2004. A pentavalent single-domain antibody approach to tumor antigen discovery and the development of novel proteomics reagents. J. Mol. Biol. 341: 161-169.
20. Sanders D. H. and Smidt, R. K. 2000. Statistics - A First Course. pp. 372-398. McGraw-Hill. New York, U. S. A.
21. Matsuda, H., Kagerura, T., Toguchida, I., Ueda, H., Morikawa, T. and Yoshikawa, M. 2000. Inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction. Life Sci. 66: 2151-2157. (Pubitemid 30313083)
22. Yuuya, S., Hagiwara, H., Suzuki, T., Ando, M., Yamada, A., Suda, K., Kataoka, T. and Nagai, K. 1999. Guaianolides as immunomodulators. Synthesis and biological activities of dehydrocostus lactone, mokko lactone, eremanthin, and their derivatives. J. Nat. Prod. 62: 22-30.
23. Mata, R., Rivero-Cruz, I., Rivero-Cruz, B., Bye, R. and Timmermann, B. N. 2002. Sesquiterpene lactones and phenylpropanoids from Cosmos pringlei. J. Nat. Prod. 65: 1030-1032.
24. Sun, C. M., Syu, W. J., Don, M. J., Lu, J. J. and Lee, G. H. 2003. Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. J. Nat. Prod. 66: 1175-1180.
25. Igarashi, M., Kitada, Y., Yoshiyama, H., Takagi, A., Miwa, T. and Koga, Y. 2001. Ammonia as an accelerator of tumor necrosis factor alpha-induced apoptosis of gastric epithelial cells in Helicobacter pylon infection. Infect. Immun. 69: 816-821.
26. Belmokhtar, C. A., Hillion, J., Dudognon, C., Fiorentino, S., Flexor, M., Lanotte, M. and Segal-Bendirdjian, E. 2003. Apoptosome-independent pathway for apoptosis, biochemical analysis of APAF-1 defects and biological outcomes. J. Biol. Chem. 278: 29571-29580.
27. Launay, S., Hermine, O., Fontenay, M., Kroemer, G., Solary, E. and Garrido, C. 2005. Vital functions for lethal caspases. Oncogene 24: 5137-5148. (Pubitemid 41192431)
28. Shih, P. H., Yeh, C. T. and Yen, G. C. 2005. Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. Food Chem. Toxicol. 43: 1557-1566.
29. Yang, J. H., Chou, C. C., Cheng, Y. W., Sheen, L. Y., Chou, M. C., Yu, H. S., Wei, Y. H. and Chung, J. G. 2004. Effects of glycolic acid on the induction of apoptosis via caspase-3 activation in human leukemia cell line (HL-60). Food Chem. Toxicol. 42: 1777-1784. (Pubitemid 39200456)
30. Manabe, N., Goto, Y., Matsuda-Minehata, F., Inoue, N., Maeda, A., Sakamaki, K. and Miyano, T. 2004. Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia. J. Reprod. Dev. 50: 493-514.
31. Baliga, B. and Kumar, S. 2003. Apaf-1/cytochrome c apoptosome: an essential initiator of caspase activation or just a sideshow? Cell Death Differ. 10: 16-18.