-
1
-
-
67650802345
-
Diphosphoinositol polyphosphates: Metabolic messengers?
-
Shears, S. B. Diphosphoinositol polyphosphates: metabolic messengers? Mol. Pharmacol. 76, 236-252 (2009).
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 236-252
-
-
Shears, S.B.1
-
2
-
-
84878393302
-
Inositol pyrophosphates: Between signalling and metabolism
-
Wilson, M. S., Livermore, T. M. & Saiardi, A. Inositol pyrophosphates: between signalling and metabolism. Biochem. J. 452, 369-379 (2013).
-
(2013)
Biochem. J.
, vol.452
, pp. 369-379
-
-
Wilson, M.S.1
Livermore, T.M.2
Saiardi, A.3
-
3
-
-
81055137383
-
Influence of inositol pyrophosphates on cellular energy dynamics
-
Szijgyarto, Z., Garedew, A., Azevedo, C. & Saiardi, A. Influence of inositol pyrophosphates on cellular energy dynamics. Science 334, 802-805 (2011).
-
(2011)
Science
, vol.334
, pp. 802-805
-
-
Szijgyarto, Z.1
Garedew, A.2
Azevedo, C.3
Saiardi, A.4
-
4
-
-
36448947507
-
Inositol pyrophosphates determine exocytic capacity
-
Illies, C. et al. Inositol pyrophosphates determine exocytic capacity. Science 318, 1299-1302 (2007).
-
(2007)
Science
, vol.318
, pp. 1299-1302
-
-
Illies, C.1
-
5
-
-
78649961357
-
Inositol pyrophosphates inhibit AKT signaling, thereby regulating insulin sensitivity and weight gain
-
Chakraborty, A. et al. Inositol pyrophosphates inhibit AKT signaling, thereby regulating insulin sensitivity and weight gain. Cell 143, 897-910 (2010).
-
(2010)
Cell
, vol.143
, pp. 897-910
-
-
Chakraborty, A.1
-
6
-
-
34147092063
-
Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates
-
DOI 10.1126/science.1139080
-
Lee, Y. S., Mulugu, S., York, J. D. & O'Shea, E. K. Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science 316, 109-112 (2007). (Pubitemid 46559529)
-
(2007)
Science
, vol.316
, Issue.5821
, pp. 109-112
-
-
Lee, Y.-S.1
Mulugu, S.2
York, J.D.3
O'Shea, E.K.4
-
7
-
-
84880062887
-
PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3, 4, 5)P3 for polyphosphoinositide-binding domains
-
Gokhale, N. A., Zaremba, A., Janoshazi, A. K., Weaver, J. D. & Shears, S. B. PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3, 4, 5)P3 for polyphosphoinositide-binding domains. Biochem. J. 453, 413-426 (2013).
-
(2013)
Biochem. J.
, vol.453
, pp. 413-426
-
-
Gokhale, N.A.1
Zaremba, A.2
Janoshazi, A.K.3
Weaver, J.D.4
Shears, S.B.5
-
8
-
-
84897449771
-
Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in type-I interferon response
-
Pulloor, N. K. et al. Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in type-I interferon response. PLoS Pathog. 10, e1003981 (2014).
-
(2014)
PLoS Pathog.
, vol.10
-
-
Pulloor, N.K.1
-
9
-
-
33645088429
-
Inositol pyrophosphates: Metabolism and signaling
-
Bennett, M., Onnebo, S. M., Azevedo, C. & Saiardi, A. Inositol pyrophosphates: metabolism and signaling. Cell. Mol. Life Sci. 63, 552-564 (2006).
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 552-564
-
-
Bennett, M.1
Onnebo, S.M.2
Azevedo, C.3
Saiardi, A.4
-
10
-
-
0033581832
-
Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases
-
Saiardi, A., Erdjument-Bromage, H., Snowman, A., Tempst, P. & Snyder, S. H. Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. Curr. Biol. 9, 1323-1326 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 1323-1326
-
-
Saiardi, A.1
Erdjument-Bromage, H.2
Snowman, A.3
Tempst, P.4
Snyder, S.H.5
-
11
-
-
0035914367
-
Identification and characterization of a novel inositol hexakisphosphate kinase
-
Saiardi, A., Nagata, E., Luo, H. R., Snowman, A. M. & Snyder, S. H. Identification and characterization of a novel inositol hexakisphosphate kinase. J. Biol. Chem. 276, 39179-39185 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39179-39185
-
-
Saiardi, A.1
Nagata, E.2
Luo, H.R.3
Snowman, A.M.4
Snyder, S.H.5
-
12
-
-
40749150040
-
Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups
-
DOI 10.1016/j.chembiol.2008.01.011, PII S1074552108000513
-
Draskovic, P. et al. Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups. Chem. Biol. 15, 274-286 (2008). (Pubitemid 351381988)
-
(2008)
Chemistry and Biology
, vol.15
, Issue.3
, pp. 274-286
-
-
Draskovic, P.1
Saiardi, A.2
Bhandari, R.3
Burton, A.4
Ilc, G.5
Kovacevic, M.6
Snyder, S.H.7
Podobnik, M.8
-
13
-
-
59449101103
-
Structural analysis and detection of biological inositol pyrophosphates reveals that the VIP/PPIP5K family are 1/3-kinases
-
Lin, H. et al. Structural analysis and detection of biological inositol pyrophosphates reveals that the VIP/PPIP5K family are 1/3-kinases. J. Biol. Chem. 284, 1863-1872 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 1863-1872
-
-
Lin, H.1
-
14
-
-
40649083560
-
Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis
-
DOI 10.1073/pnas.0712227105
-
Bhandari, R., Juluri, K. R., Resnick, A. C. & Snyder, S. H. Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis. Proc. Natl Acad. Sci. USA 105, 2349-2353 (2008). (Pubitemid 351520516)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.7
, pp. 2349-2353
-
-
Bhandari, R.1
Juluri, K.R.2
Resnick, A.C.3
Snyder, S.H.4
-
15
-
-
84886805114
-
Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels
-
Ghosh, S. et al. Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels. Blood 122, 1478-1486 (2013).
-
(2013)
Blood
, vol.122
, pp. 1478-1486
-
-
Ghosh, S.1
-
16
-
-
84873307807
-
Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair
-
Jadav, R. S., Chanduri, M. V., Sengupta, S. & Bhandari, R. Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair. J. Biol. Chem. 288, 3312-3321 (2012).
-
(2012)
J. Biol. Chem.
, vol.288
, pp. 3312-3321
-
-
Jadav, R.S.1
Chanduri, M.V.2
Sengupta, S.3
Bhandari, R.4
-
17
-
-
84888102525
-
Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation
-
Burton, A., Azevedo, C., Andreassi, C., Riccio, A. & Saiardi, A. Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation. Proc. Natl Acad. Sci. USA 110, 18970-18975 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 18970-18975
-
-
Burton, A.1
Azevedo, C.2
Andreassi, C.3
Riccio, A.4
Saiardi, A.5
-
18
-
-
0035816638
-
Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-b in ovarian carcinoma cells
-
Morrison, B. H., Bauer, J. A., Kalvakolanu, D. V. & Lindner, D. J. Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-b in ovarian carcinoma cells. J. Biol. Chem. 276, 24965-24970 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24965-24970
-
-
Morrison, B.H.1
Bauer, J.A.2
Kalvakolanu, D.V.3
Lindner, D.J.4
-
19
-
-
67650001655
-
Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma
-
Morrison, B. H. et al. Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma. Oncogene 28, 2383-2392 (2009).
-
(2009)
Oncogene
, vol.28
, pp. 2383-2392
-
-
Morrison, B.H.1
-
20
-
-
81155134742
-
A novel Entamoeba histolytica inositol phosphate kinase catalyzes the formation of 5PP-Ins(1, 2, 3, 4, 6)P(5)
-
Loser, B. et al. A novel Entamoeba histolytica inositol phosphate kinase catalyzes the formation of 5PP-Ins(1, 2, 3, 4, 6)P(5). Mol. Biochem. Parasitol. 181, 49-52 (2012).
-
(2012)
Mol. Biochem. Parasitol.
, vol.181
, pp. 49-52
-
-
Loser, B.1
-
21
-
-
0034677903
-
A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control
-
DOI 10.1126/science.287.5460.2026
-
Odom, A. R., Stahlberg, A., Wente, S. R. & York, J. D. A role for nuclear inositol 1, 4, 5-trisphosphate kinase in transcriptional control. Science 287, 2026-2029 (2000). (Pubitemid 30158681)
-
(2000)
Science
, vol.287
, Issue.5460
, pp. 2026-2029
-
-
Odom, A.R.1
Stahlberg, A.2
Wente, S.R.3
York, J.D.4
-
22
-
-
0033975636
-
Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae
-
DOI 10.1016/S0014-5793(00)01194-7, PII S0014579300011947
-
Saiardi, A., Caffrey, J. J., Snyder, S. H. & Shears, S. B. Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae. FEBS Lett. 468, 28-32 (2000). (Pubitemid 30101676)
-
(2000)
FEBS Letters
, vol.468
, Issue.1
, pp. 28-32
-
-
Saiardi, A.1
Caffrey, J.J.2
Snyder, S.H.3
Shears, S.B.4
-
23
-
-
0347722634
-
The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase
-
DOI 10.1074/jbc.M206134200
-
Chang, S.-C., Miller, A. L., Feng, Y., Wente, S. R. & Majerus, P. W. The human homologue of the rat inositol phosphate multikinase is an inositol 1, 3, 4, 6-tetrakisphosphate 5-kinase. J. Biol. Chem. 277, 43836-43843 (2002). (Pubitemid 36157805)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 43836-43843
-
-
Chang, S.-C.1
Miller, A.L.2
Feng, Y.3
Wente, S.R.4
Majerus, P.W.5
-
24
-
-
0034331885
-
Multitasking in signal transduction by a promiscuous human Ins(3, 4, 5, 6)P4 1-Kinase/Ins(1, 3, 4)P3 5/6-Kinase
-
Yang, X. & Shears, S. B. Multitasking in signal transduction by a promiscuous human Ins(3, 4, 5, 6)P4 1-Kinase/Ins(1, 3, 4)P3 5/6-Kinase. Biochem. J. 351, 551-555 (2000).
-
(2000)
Biochem. J.
, vol.351
, pp. 551-555
-
-
Yang, X.1
Shears, S.B.2
-
25
-
-
0942290439
-
How versatile are inositol phosphate kinases?
-
DOI 10.1042/BJ20031428
-
Shears, S. B. How versatile are inositol phosphate kinases? Biochem. J. 377, 265-280 (2004). (Pubitemid 38142182)
-
(2004)
Biochemical Journal
, vol.377
, Issue.2
, pp. 265-280
-
-
Shears, S.B.1
-
26
-
-
33845992536
-
Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity
-
DOI 10.1074/jbc.M606883200
-
Holmes, W. & Jogl, G. Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity. J. Biol. Chem. 281, 38109-38116 (2006). (Pubitemid 46042114)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.49
, pp. 38109-38116
-
-
Holmes, W.1
Jogl, G.2
-
27
-
-
17044363986
-
Specificity determinants in inositol polyphosphate synthesis: Crystal structure of inositol 1, 3, 4-trisphosphate 5/6-kinase
-
Miller, G. J., Wilson, M. P., Majerus, P. W. & Hurley, J. H. Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1, 3, 4-trisphosphate 5/6-kinase. Mol. Cell 18, 201-212 (2005).
-
(2005)
Mol. Cell
, vol.18
, pp. 201-212
-
-
Miller, G.J.1
Wilson, M.P.2
Majerus, P.W.3
Hurley, J.H.4
-
28
-
-
84867423671
-
Structural studies and protein engineering of inositol phosphate multikinase
-
Endo-Streeter, S., Tsui, M. K., Odom, A. R., Block, J. & York, J. D. Structural studies and protein engineering of inositol phosphate multikinase. J. Biol. Chem. 287, 35360-35369 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 35360-35369
-
-
Endo-Streeter, S.1
Tsui, M.K.2
Odom, A.R.3
Block, J.4
York, J.D.5
-
29
-
-
34948910270
-
Integration of inositol phosphate signaling pathways via human ITPK1
-
DOI 10.1074/jbc.M703121200
-
Chamberlain, P. P. et al. Integration of inositol phosphate signaling pathways via human ITPK1. J. Biol. Chem. 282, 28117-28125 (2007). (Pubitemid 47529547)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.38
, pp. 28117-28125
-
-
Chamberlain, P.P.1
Qian, X.2
Stiles, A.R.3
Cho, J.4
Jones, D.H.5
Lesley, S.A.6
Grabau, E.A.7
Shears, S.B.8
Spraggon, G.9
-
30
-
-
77953623874
-
Enzyme promiscuity: A mechanistic and evolutionary perspective
-
Khersonsky, O. & Tawfik, D. S. Enzyme promiscuity: a mechanistic and evolutionary perspective. Annu. Rev. Biochem. 79, 471-505 (2010).
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 471-505
-
-
Khersonsky, O.1
Tawfik, D.S.2
-
31
-
-
4444230351
-
Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase
-
DOI 10.1016/j.molcel.2004.08.005, PII S1097276504004691
-
Miller, G. J. & Hurley, J. H. Crystal structure of the catalytic core of inositol 1, 4, 5-trisphosphate 3-kinase. Mol. Cell. 15, 703-711 (2004). (Pubitemid 39194901)
-
(2004)
Molecular Cell
, vol.15
, Issue.5
, pp. 703-711
-
-
Miller, G.J.1
Hurley, J.H.2
-
32
-
-
4444223742
-
Structure of a human inositol 1,4,5-trisphosphate 3-kinase: Substrate binding reveals why it is not a phosphoinositide 3-kinase
-
DOI 10.1016/j.molcel.2004.08.004, PII S109727650400468X
-
Gonzalez, B. et al. Structure of a human inositol 1, 4, 5-trisphosphate 3-kinase; substrate binding reveals why it is not a phosphoinositide 3-kinase. Mol. Cell 15, 689-701 (2004). (Pubitemid 39194900)
-
(2004)
Molecular Cell
, vol.15
, Issue.5
, pp. 689-701
-
-
Gonzalez, B.1
Schell, M.J.2
Letcher, A.J.3
Veprintsev, D.B.4
Irvine, R.F.5
Williams, R.L.6
-
33
-
-
0030668774
-
Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells
-
Albert, C. et al. Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells. Biochem. J. 327, 553-560 (1997). (Pubitemid 27477836)
-
(1997)
Biochemical Journal
, vol.327
, Issue.2
, pp. 553-560
-
-
Albert, C.1
Safrany, S.T.2
Bembenek, M.E.3
Reddy, K.M.4
Reddy, K.K.5
Falck, J.R.6
Brocker, M.7
Shears, S.B.8
Mayr, G.W.9
-
34
-
-
84886308085
-
Understanding inositol pyrophosphate metabolism and function: Kinetic characterization of the DIPPs
-
Kilari, R. S., Weaver, J. D., Shears, S. B. & Safrany, S. T. Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs. FEBS Lett. 587, 3464-3470 (2013).
-
(2013)
FEBS Lett.
, vol.587
, pp. 3464-3470
-
-
Kilari, R.S.1
Weaver, J.D.2
Shears, S.B.3
Safrany, S.T.4
-
35
-
-
70849090308
-
Inositol pyrophosphates: Structure, enzymology and function
-
Barker, C. J., Illies, C., Gaboardi, G. C. & Berggren, P. O. Inositol pyrophosphates: structure, enzymology and function. Cell. Mol. Life Sci. 66, 3851-3871 (2009).
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3851-3871
-
-
Barker, C.J.1
Illies, C.2
Gaboardi, G.C.3
Berggren, P.O.4
-
36
-
-
0034637548
-
The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis
-
DOI 10.1074/jbc.M002750200
-
Saiardi, A., Caffrey, J. J., Snyder, S. H. & Shears, S. B. The inositol hexakisphosphate kinase family: catalytic flexibility, and function in yeast vacuole biogenesis. J. Biol. Chem. 275, 24686-24692 (2000). (Pubitemid 30626569)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.32
, pp. 24686-24692
-
-
Saiardi, A.1
Caffrey, J.J.2
Snyder, S.H.3
Shears, S.B.4
-
37
-
-
0037199965
-
The synthesis of inositol hexakisphosphate: Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase
-
DOI 10.1074/jbc.M205682200
-
Verbsky, J. W., Wilson, M. P., Kisseleva, M. V., Majerus, P. W. & Wente, S. R. The synthesis of inositol hexakisphosphate: characterization of human inositol 1, 3, 4, 5, 6-pentakisphosphate 2-kinase. J. Biol. Chem. 277, 31857-31862 (2002). (Pubitemid 34968993)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.35
, pp. 31857-31862
-
-
Verbsky, J.W.1
Wilson, M.P.2
Kisseleva, M.V.3
Majerus, P.W.4
Wente, S.R.5
-
38
-
-
0032538976
-
A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase
-
Safrany, S. T. et al. A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase. EMBO J. 17, 6599-6607 (1998). (Pubitemid 28521794)
-
(1998)
EMBO Journal
, vol.17
, Issue.22
, pp. 6599-6607
-
-
Safrany, S.T.1
Caffrey, J.J.2
Yang, X.3
Bembenek, M.E.4
Moyer, M.B.5
Burkhart, W.A.6
Shears, S.B.7
-
39
-
-
78650055985
-
3(10) helices in channels and other membrane proteins
-
Vieira-Pires, R. S. & Morais-Cabral, J. H. 3(10) helices in channels and other membrane proteins. J. Gen. Physiol. 136, 585-592 (2010).
-
(2010)
J. Gen. Physiol.
, vol.136
, pp. 585-592
-
-
Vieira-Pires, R.S.1
Morais-Cabral, J.H.2
-
40
-
-
0032692474
-
10-helices
-
Pal, L. & Basu, G. Novel protein structural motifs containing two-turn and longer 3(10)-helices. Protein Eng. 12, 811-814 (1999). (Pubitemid 29533103)
-
(1999)
Protein Engineering
, vol.12
, Issue.10
, pp. 811-814
-
-
Pal, L.1
Basu, G.2
-
41
-
-
67449093365
-
Characterization of a selective inhibitor of inositol hexakisphosphate kinases: Use in defining biological roles and metabolic relationships of inositol pyrophosphates
-
Padmanabhan, U., Dollins, D. E., Fridy, P. C., York, J. D. & Downes, C. P. Characterization of a selective inhibitor of inositol hexakisphosphate kinases: Use in defining biological roles and metabolic relationships of inositol pyrophosphates. J. Biol. Chem. 284, 10571-10582 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 10571-10582
-
-
Padmanabhan, U.1
Dollins, D.E.2
Fridy, P.C.3
York, J.D.4
Downes, C.P.5
-
42
-
-
0030724727
-
Mechanisms of signaling and related enzymes
-
DOI 10.1002/(SICI)1097-0134 (199712)29: 4<401::AID-PROT1>3.0.CO;2-B
-
Mildvan, A. S. Mechanisms of signaling and related enzymes. Proteins 29, 401-416 (1997). (Pubitemid 27520194)
-
(1997)
Proteins: Structure, Function and Genetics
, vol.29
, Issue.4
, pp. 401-416
-
-
Mildvan, A.S.1
-
43
-
-
12544255427
-
Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death
-
Nagata, E. et al. Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death. J. Biol. Chem. 280, 1634-1640 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1634-1640
-
-
Nagata, E.1
-
44
-
-
77953097386
-
Inositol 1, 3, 4, 5, 6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition
-
Gonzalez, B., Banos-Sanz, J. I., Villate, M., Brearley, C. A. & Sanz-Aparicio, J. Inositol 1, 3, 4, 5, 6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition. Proc. Natl Acad. Sci. USA 107, 9608-9613 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 9608-9613
-
-
Gonzalez, B.1
Banos-Sanz, J.I.2
Villate, M.3
Brearley, C.A.4
Sanz-Aparicio, J.5
-
45
-
-
83655198346
-
Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding
-
Wang, H., Falck, J. R., Hall, T. M. & Shears, S. B. Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat. Chem. Biol. 8, 111-116 (2012).
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 111-116
-
-
Wang, H.1
Falck, J.R.2
Hall, T.M.3
Shears, S.B.4
-
46
-
-
0033544954
-
Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates
-
Yang, X., Safrany, S. T. & Shears, S. B. Site-directed mutagenesis of DIPP, a dual specificity MutT/Nudix-type hydrolase that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates. J. Biol. Chem. 274, 35434-35440 (1999). (Pubitemid 129512834)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.50
, pp. 35434-35440
-
-
Yang, X.1
Safrany, S.T.2
Shears, S.B.3
-
47
-
-
0025949438
-
Multiple isomers of inositol pentakisphosphate in Epstein-Barr-virus- transformed (T5-1) B-lymphocytes. Identification of inositol 1, 3, 4, 5, 6-pentakisphosphate, D-inositol 1, 2, 4, 5, 6-pentakisphosphate and L-inositol 1, 2, 4, 5, 6-pentakisphosphate
-
McConnell, F. M., Stephens, L. R. & Shears, S. B. Multiple isomers of inositol pentakisphosphate in Epstein-Barr-virus-transformed (T5-1) B-lymphocytes. Identification of inositol 1, 3, 4, 5, 6-pentakisphosphate, D-inositol 1, 2, 4, 5, 6-pentakisphosphate and L-inositol 1, 2, 4, 5, 6-pentakisphosphate. Biochem. J. 280, 323-329 (1991).
-
(1991)
Biochem. J.
, vol.280
, pp. 323-329
-
-
McConnell, F.M.1
Stephens, L.R.2
Shears, S.B.3
-
48
-
-
84877764863
-
The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment
-
Weaver, J. D., Wang, H. & Shears, S. B. The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment. Biosci. Rep. 33, 228-241 (2013).
-
(2013)
Biosci. Rep.
, vol.33
, pp. 228-241
-
-
Weaver, J.D.1
Wang, H.2
Shears, S.B.3
-
49
-
-
0032536857
-
2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism
-
DOI 10.1093/emboj/17.6.1710
-
2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism. EMBO J. 17, 1710-1716 (1998). (Pubitemid 28119124)
-
(1998)
EMBO Journal
, vol.17
, Issue.6
, pp. 1710-1716
-
-
Safrany, S.T.1
Shears, S.B.2
-
50
-
-
0030020874
-
Metabolic evidence for the order of addition of individual phosphate esters to the myo-inositol moiety of inositol hexakisphosphate in the duckweed Spirodela polrhiza L
-
Brearley, C. A. & Hanke, D. E. Metabolic evidence for the order of addition of individual phosphate esters to the myo-inositol moiety of inositol hexakisphosphate in the duckweed Spirodela polrhiza L. Biochem. J. 314, 227-233 (1996).
-
(1996)
Biochem. J.
, vol.314
, pp. 227-233
-
-
Brearley, C.A.1
Hanke, D.E.2
-
51
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
DOI 10.1016/S0076-6879(97)76066-X
-
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997). (Pubitemid 27085611)
-
(1997)
Methods in Enzymology
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
53
-
-
0013461295
-
Macromolecular TLS Refinement in REFMAC at moderate resolutions
-
DOI 10.1016/S0076-6879(03)74014-2
-
Winn, M. D., Murshudov, G. N. & Papiz, M. Z. Macromolecular TLS refinement in REFMAC at moderate resolutions. Methods Enzymol. 374, 300-321 (2003). (Pubitemid 37531815)
-
(2003)
Methods in Enzymology
, vol.374
, pp. 300-321
-
-
Winn, M.D.1
Murshudov, G.N.2
Papiz, M.Z.3
-
54
-
-
39549102614
-
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2
-
DOI 10.1073/pnas.0711168105
-
Chakraborty, A. et al. HSP90 regulates cell survival via inositol hexakisphosphate kinase-2. Proc. Natl Acad. Sci. USA 105, 1134-1139 (2008). (Pubitemid 351397019)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.4
, pp. 1134-1139
-
-
Chakraborty, A.1
Koldobskiy, M.A.2
Sixt, K.M.3
Juluri, K.R.4
Mustafa, A.K.5
Snowman, A.M.6
Van Rossum, D.B.7
Patterson, R.L.8
Snyder, S.H.9
-
55
-
-
79952303278
-
Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2
-
Chakraborty, A. et al. Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2. Proc. Natl Acad. Sci. USA 108, 2205-2209 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 2205-2209
-
-
Chakraborty, A.1
|