Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 21, 2010, Pages 9608-9613

  González, Beatriz ^a   Baños Sanz, Jose Ignacio ^a   Villate, Maider ^a   Brearley, Charles Alistair ^b   Sanz Aparicio, Julia ^a  

^a INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Crystal structure; InsP5 2 kinase; IP5; IP6; Ipk1

Indexed keywords

ADENOSINE TRIPHOSPHATE; INOSITOL 1,3,4,5,6 PENTAKISPHOSPHATE 2 KINASE; INOSITOL PHOSPHATE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; ZINC BINDING PROTEIN;

ARTICLE; CATALYSIS; METAL BINDING; MUTAGENESIS; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN MOTIF; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; ARABIDOPSIS; BINDING SITES; HUMANS; INOSITOL PHOSPHATES; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; WATER;

EID: 77953097386     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912979107     Document Type: Article

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