Imatinib Treatment Causes Substantial Transcriptional Changes in Adult Schistosoma mansoni In Vitro Exhibiting Pleiotropic Effects

PLoS Neglected Tropical Diseases

Volumn 8, Issue 6, 2014, Pages

  Buro, Christin ^a,e   Beckmann, Svenja ^a   Oliveira, Katia C ^b,f   Dissous, Colette ^c   Cailliau, Katia ^c   Marhöfer, Richard J ^d   Selzer, Paul M ^d   Verjovski Almeida, Sergio ^b   Grevelding, Christoph G ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIV LILLE   (France)

^d Intervet Innovation GmbH   (Germany)

^e JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^f INSTITUTO ADOLFO LUTZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; IMATINIB; TRANSCRIPTOME; ANTHELMINTIC AGENT; BENZAMIDE DERIVATIVE; PIPERAZINE DERIVATIVE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

ARTICLE; BIOMPHALARIA GLABRATA; COMPUTER MODEL; CONTROLLED STUDY; DNA TRANSCRIPTION; ENZYME ACTIVITY; FEMALE; IN VITRO STUDY; MALE; MICROARRAY ANALYSIS; MOLECULAR DOCKING; PLEIOTROPY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SEQUENCE HOMOLOGY; SYRIAN HAMSTER; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; ANTHELMINTICS; BENZAMIDES; GENE EXPRESSION REGULATION; MICROARRAY ANALYSIS; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PYRIMIDINES; REAL-TIME POLYMERASE CHAIN REACTION; SCHISTOSOMA MANSONI; TRANSCRIPTION, GENETIC;

EID: 84903467350     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0002923     Document Type: Article

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