Rift Valley Fever Virus Encephalitis Is Associated with an Ineffective Systemic Immune Response and Activated T Cell Infiltration into the CNS in an Immunocompetent Mouse Model

PLoS Neglected Tropical Diseases

Volumn 8, Issue 6, 2014, Pages

  Dodd, Kimberly A ^a,b   McElroy, Anita K ^a,c   Jones, Tara L ^a   Zaki, Sherif R ^a   Nichol, Stuart T ^a   Spiropoulou, Christina F ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; BLOOD BRAIN BARRIER; BRAIN; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIFT VALLEY FEVER; RNA EXTRACTION; SPLEEN CELL; T LYMPHOCYTE; VIRUS LOAD; VIRUS NEUTRALIZATION; VIRUS REPLICATION; AFRICA; ANIMAL; C57BL MOUSE; DISEASE MODEL; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PATHOLOGY; PHYSIOLOGY; RIFT VALLEY FEVER VIRUS; SURVIVAL; VIRUS ENCEPHALITIS;

AFRICA; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; ENCEPHALITIS, VIRAL; FEMALE; HUMANS; LYMPHOCYTE ACTIVATION; MICE, INBRED C57BL; RIFT VALLEY FEVER; RIFT VALLEY FEVER VIRUS; SURVIVAL; T-LYMPHOCYTES; VIRUS REPLICATION;

EID: 84903466988     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0002874     Document Type: Article

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