Dual functions of rift valley fever virus NSs protein: Inhibition of host mRNA transcription and post-transcriptional downregulation of protein kinase PKR

Annals of the New York Academy of Sciences

Volumn 1171, Issue SUPPL. 1, 2009, Pages

  Ikegami, Tetsuro ^a,b   Narayanan, Krishna ^a   Won, Sungyong ^a   Kamitani, Wataru ^a   Peters, C J ^a,b   Makino, Shinji ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

interferon; NSs protein; PKR; Rift Valley fever virus; transcriptional suppression

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; INITIATION FACTOR 2ALPHA; MESSENGER RNA; NONSTRUCTURED PROTEIN; PROTEIN KINASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; VIRUS PROTEIN; PROTEIN KINASE R; VIRUS RNA;

BIOLOGICAL ACTIVITY; DOWN REGULATION; ENCEPHALITIS; ENZYME PHOSPHORYLATION; EYE DISEASE; HEMORRHAGIC FEVER; HUMAN; INNATE IMMUNITY; MOSQUITO; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; RIFT VALLEY FEVER BUNYAVIRUS; TRANSCRIPTION REGULATION; VIRAL GENETICS; VIRUS REPLICATION; VIRUS TRANSCRIPTION; ANIMAL; ARTICLE; BOVIDS; BREEDING; DISEASE TRANSMISSION; FEMALE; GENETIC TRANSCRIPTION; GENETICS; PREGNANCY; PROTEIN SYNTHESIS; RNA VIRUS; SPONTANEOUS ABORTION; VIROLOGY; VIRUS GENOME;

BUNYAVIRIDAE; MAMMALIA; PHLEBOVIRUS; RIFT VALLEY FEVER VIRUS; RNA VIRUSES;

ABORTION, SPONTANEOUS; ANIMALS; CULICIDAE; DOWN-REGULATION; EIF-2 KINASE; FEMALE; GENOME, VIRAL; HUMANS; PREGNANCY; PREGNANCY, ANIMAL; PROTEIN BIOSYNTHESIS; RIFT VALLEY FEVER; RIFT VALLEY FEVER VIRUS; RNA VIRUSES; RNA, MESSENGER; RNA, VIRAL; RUMINANTS; TRANSCRIPTION, GENETIC; VIRAL PROTEINS;

EID: 70350435722     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05054.x     Document Type: Review

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