Infection and transmission of rift valley fever viruses lacking the NSs and/or NSm genes in mosquitoes: Potential role for NSm in mosquito infection

PLoS Neglected Tropical Diseases

Volumn 6, Issue 5, 2012, Pages

  Crabtree, Mary B ^a   Crockett, Rebekah J ^a   Bird, Brian H ^a   Nichol, Stuart T ^a   Erickson, Bobbie Rae ^a   Biggerstaff, Brad J ^a   Horiuchi, Kalanthe ^a   Miller, Barry R ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN; VIRULENCE FACTOR;

AEDES AEGYPTI; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CULEX QUINQUEFASCIATUS; DNA SEQUENCE; GENE; GENE DELETION; INFECTION RATE; NONHUMAN; NONSTRUCTURAL MEDIUM VIRUS PROTEIN GENE; NONSTRUCTURAL SMALL VIRUS PROTEIN GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIFT VALLEY FEVER; RIFT VALLEY FEVER BUNYAVIRUS; VIRUS REPLICATION; VIRUS TRANSMISSION; AEDES; AFRICA; ANIMAL; CULEX; DISEASE TRANSMISSION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; VIROLOGY;

AEDES; AFRICA; ANIMALS; CULEX; GENE DELETION; HUMANS; RIFT VALLEY FEVER; RIFT VALLEY FEVER VIRUS; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE FACTORS;

EID: 84863641669     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001639     Document Type: Article

References (48)

1. Al-Afaleq AI, Hussein MF, (2011) The status of Rift Valley fever in animals in Saudi Arabia: a mini review. Vector Borne Zoonotic Dis 11: 1513-1520.
2. Elfadil AA, Hasab-Allah KA, Dafa-Allah OM, Elmanea AA, (2006) The persistence of Rift Valley fever in the Jazan region of Saudi Arabia. Rev Sci Tech 25: 1131-1136.
3. Bird BH, Ksiazek TG, Nichol ST, Maclachlan NJ, (2009) Rift Valley fever virus. J Am Vet Med Assoc 234: 883-893.
4. Pepin M, Bouloy M, Bird BH, Kemp A, Paweska J, (2010) Rift Valley fever virus (Bunyaviridae: Phlebovirus): an update on pathogenesis, molecular epidemiology, vectors, diagnostics and prevention. Vet Res 41: 61.
5. Sang R, Kioko E, Lutomiah J, Warigia M, Ochieng C, et al. (2010) Rift Valley fever virus epidemic in Kenya, 2006/2007: the entomologic investigations. Am J Trop Med Hyg 83: 28-37.
6. Morvan J, Rollin PE, Laventure S, Rakotoarivony I, Roux J, (1992) Rift Valley fever epizootic in the central highlands of Madagascar. Res Virol 143: 407-415.
7. Al-Hazmi M, Ayoola EA, Abdurahman M, Banzal S, Ashraf J, et al. (2003) Epidemic Rift Valley fever in Saudi Arabia: a clinical study of severe illness in humans. Clin Infect Dis 36: 245-252.
8. Alrajhi AA, Al-Semari A, Al-Watban J, (2004) Rift Valley fever encephalitis. Emerg Infect Dis 10: 554-555.
9. Meegan JM, (1979) The Rift Valley fever epizootic in Egypt 1977-78. 1. Description of the epizootic and virological studies. Trans R Soc Trop Med Hy 73: 618-623.
10. Fontenille D, Traore-Lamizana M, Diallo M, Thonnon J, Digoutte JP, et al. (1998) New vectors of Rift Valley fever in West Africa. Emerg Infect Dis 4: 289-293.
11. Lee VH, (1979) Isolation of viruses from field populations of culicoides (Diptera: Ceratopogonidae) in Nigeria. J Med Entomol 16: 76-79.
12. Miller BR, Godsey MS, Crabtree MB, Savage HM, Al-Mazrao Y, et al. (2002) Isolation and genetic characterization of Rift Valley fever virus from Aedes vexans arabiensis, Kingdom of Saudi Arabia. Emerg Infect Dis 8: 1492-1494.
13. Turell MJ, Linthicum KJ, Patrican LA, Davies FG, Kairo A, et al. (2008) Vector competence of selected African mosquito (Diptera: Culicidae) species for Rift Valley fever virus. J Med Entomol 45: 102-108.
14. Turell MJ, Gargan TP 2nd, Bailey CL, (1984) Replication and dissemination of Rift Valley fever virus in Culex pipiens. Am J Trop Med Hyg 33: 176-181.
15. Turell MJ, Dohm DJ, Mores CN, Terracina L, Wallette DL Jr, et al. (2008) Potential for North American mosquitoes to transmit Rift Valley fever virus. J Am Mosq Control Assoc 24: 502-507.
16. Turell MJ, Wilson WC, Bennett KE, (2010) Potential for North American mosquitoes (Diptera: Culicidae) to transmit Rift Valley fever virus. J Med Entomol 47: 884-889.
17. Gargan TP 2nd, Clark GG, Dohm DJ, Turell MJ, Bailey CL, (1988) Vector potential of selected North American mosquito species for Rift Valley fever virus. Am J Trop Med Hyg 38: 440-446.
18. Hardy JL, (1988) Susceptibility and resistance of vector mosquitoes. In: Monath TP, editors. The Arboviruses: Ecology and Epidemiology Boca Raton CRC pp. 87-126.
19. Mellor PS, (2000) Replication of arboviruses in insect vectors. J Comp Pathol 123: 231-247.
20. Habjan M, Pichlmair A, Elliott RM, Overby AK, Glatter T, et al. (2009) NSs protein of Rift Valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase. J Virol 83: 4365-4375.
21. Kalveram B, Lihoradova O, Ikegami T, (2011) NSs Protein of Rift Valley Fever virus promotes posttranslational downregulation of the TFIIH subunit p62. J Virol 85: 6234-6243.
22. Bouloy M, Janzen C, Vialat P, Khun H, Pavlovic J, et al. (2001) Genetic evidence for an interferon-antagonistic function of Rift Valley fever virus nonstructural protein NSs. J Virol 75: 1371-1377.
23. Billecocq A, Spiegel M, Vialat P, Kohl A, Weber F, et al. (2004) NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription. J Virol 78: 9798-9806.
24. Le May N, Dubaele S, Proietti De Santis L, Billecocq A, Bouloy M, et al. (2004) TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus. Cell 116: 541-550.
25. Gerrard SR, Bird BH, Albarino CG, Nichol ST, (2007) The NSm proteins of Rift Valley fever virus are dispensable for maturation, replication and infection. Virol 359: 459-465.
26. Won S, Ikegami T, Peters CJ, Makino S, (2007) NSm protein of Rift Valley fever virus suppresses virus-induced apoptosis. J Virol 81: 13335-13345.
27. Won S, Ikegami T, Peters CJ, Makino S, (2006) NSm and 78-kilodalton proteins of Rift Valley fever virus are nonessential for viral replication in cell culture. J Virol 80: 8274-8278.
28. Bouloy M, Flick R, (2009) Reverse genetics technology for Rift Valley fever virus: current and future applications for the development of therapeutics and vaccines. Antiviral Res 84: 101-118.
29. Bird BH, Albarino CG, Hartman AL, Erickson BR, Ksiazek TG, et al. (2008) Rift valley fever virus lacking the NSs and NSm genes is highly attenuated, confers protective immunity from virulent virus challenge, and allows for differential identification of infected and vaccinated animals. J Virol 82: 2681-2691.
30. McElroy AK, Albarino CG, Nichol ST, (2009) Development of a RVFV ELISA that can distinguish infected from vaccinated animals. Virol J 6: 125.
31. Bird BH, Albarino CG, Nichol ST, (2007) Rift Valley fever virus lacking NSm proteins retains high virulence in vivo and may provide a model of human delayed onset neurologic disease. Virol 362: 10-15.
32. Bird BH, Khristova ML, Rollin PE, Ksiazek TG, Nichol ST, (2007) Complete genome analysis of 33 ecologically and biologically diverse Rift Valley fever virus strains reveals widespread virus movement and low genetic diversity due to recent common ancestry. J Virol 81: 2805-2816.
33. Miller BR, Mitchell CJ, Ballinger ME, (1989) Replication, tissue tropisms and transmission of Yellow fever virus in Aedes albopictus. Trans R Soc Trop Med Hyg 83: 252-255.
34. Miller BR, Mitchell CJ, (1991) Genetic selection of a flavivirus-refractory strain of the Yellow fever mosquito Aedes aegypti. Am J Trop Med Hyg 45: 399-407.
35. Vanlandingham DL, McGee CE, Klingler KA, Galbraith SE, Barrett AD, et al. (2008) Short report: comparison of oral infectious dose of West Nile virus isolates representing three distinct genotypes in Culex quinquefasciatus. Am J Trop Med Hyg 79: 951-954.
36. Carpenter SJ, LaCasse WJ, (1955) Mosquitoes of North America (north of Mexico): University of California Press.
37. Kothera L, Zimmerman EM, Richards CM, Savage HM, (2009) Microsatellite characterization of subspecies and their hybrids in Culex pipiens complex (Diptera: Culicidae) mosquitoes along a north-south transect in the central United States. J Med Entomol 46: 236-248.
38. Savage HM, Aggarwal D, Apperson CS, Katholi CR, Gordon E, et al. (2007) Host choice and West Nile virus infection rates in blood-fed mosquitoes, including members of the Culex pipiens complex, from Memphis and Shelby County, Tennessee, 2002-2003. Vector Borne Zoonotic Dis 7: 365-386.
39. Moutailler S, Krida G, Schaffner F, Vazeille M, Failloux AB, (2008) Potential vectors of Rift Valley fever virus in the Mediterranean region. Vector Borne Zoonotic Dis 8: 749-753.
40. Kent RJ, Crabtree MB, Miller BR, (2010) Transmission of West Nile virus by Culex quinquefasciatus Say infected with Culex Flavivirus Izabal. PLoS Negl Trop Dis 4: e671.
41. Heinze G, Puhr R, (2010) Bias-reduced and separation-proof conditional logistic regression with small or sparse data sets. Stat Med 29: 770-777.
42. Heinze G, Schemper M, (2002) A solution to the problem of separation in logistic regression. Stat Med 21: 2409-2419.
43. Hothorn T, Bretz F, Westfall P, (2008) Simultaneous inference in general parametric models. Biom J 50: 346-363.
44. Little R, Rubin D, (2002) Statistical Analysis with Missing Data. 2nd ed Hoboken John Wiley & Sons, Inc.
45. Turell MJ, Lee JS, Richardson JH, Sang RC, Kioko EN, et al. (2007) Vector competence of Kenyan Culex zombaensis and Culex quinquefasciatus mosquitoes for Rift Valley fever virus. J Am Mosq Control Assoc 23: 378-382.
46. Moutailler S, Krida G, Madec Y, Bouloy M, Failloux AB, (2010) Replication of Clone 13, a naturally attenuated avirulent isolate of Rift Valley fever virus, in Aedes and Culex mosquitoes. Vector Borne Zoonotic Dis 10: 681-688.
47. Bird BH, Maartens LH, Campbell S, Erasmus BJ, Erickson BR, et al. (2011) Rift Valley fever virus vaccine lacking the NSs and NSm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheep. J Virol 85: 12901-12909.
48. Turell MJ, Saluzzo J-F, Tammariello RF, Smith JF, (1990) Generation and transmission of Rift Valley fever viral reassortants by the mosquito Culex pipiens. J Gen Virol 71: 2307-2312.