Gene therapy for tolerance: High-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin grafts

Transplantation

Volumn 95, Issue 1, 2013, Pages 70-77

  Cunningham, Eithne C ^a   Tay, Szun S ^a   Wang, Chuanmin ^a   Rtshiladze, Michael ^a   Wang, Zane Z ^a   McGuffog, Claire ^a   Cubitt, Jonathan ^a   McCaughan, Geoffrey W ^a   Alexander, Ian E ^b   Bertolino, Patrick ^a   Sharland, Alexandra F ^a   Bowen, David G ^a   Bishop, G Alex ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Gene therapy; Liver; Skin transplant; Tolerance; Vaccination

Indexed keywords

ALANINE AMINOTRANSFERASE; EPITOPE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN; PARVOVIRUS VECTOR; PROTEIN H 2KB; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALLOIMMUNITY; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; GRAFT RECIPIENT; GRAFT REJECTION; HEART TRANSPLANTATION; HISTOPATHOLOGY; IMMUNOLOGICAL TOLERANCE; LIVER CELL; LIVING DONOR; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN GRAFT REJECTION; SKIN TRANSPLANTATION; SPLEEN CELL; SURVIVAL TIME; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ANIMALS; DEPENDOVIRUS; GENETIC THERAPY; GRAFT REJECTION; H-2 ANTIGENS; IMMUNE TOLERANCE; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; LIVER; MICE; MICE, INBRED C57BL; SKIN TRANSPLANTATION; T-LYMPHOCYTES; TISSUE DONORS;

EID: 84872078900     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e318278d39a     Document Type: Article

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