메뉴 건너뛰기




Volumn 1, Issue 2, 2014, Pages 132-147

The Effects of Arsenic Exposure on Neurological and Cognitive Dysfunction in Human and Rodent Studies: A Review

Author keywords

Adult; Alzheimer s disease; Anxiety; Arsenate; Arsenic; Arsenite; Children; Cholinergic; Cognition; Cortisol; Depression; Development; DNA methylation; Epigenetics; Exposure; Glucocorticoid receptor; Glutamatergic; Histone modifications; HPA; IQ; Lead; Monoaminergic; Mood disorders; Neurogenesis; Neurological deficits; Neurotoxicity; Teratogen

Indexed keywords


EID: 84903439589     PISSN: None     EISSN: 21965412     Source Type: Journal    
DOI: 10.1007/s40572-014-0012-1     Document Type: Review
Times cited : (385)

References (119)
  • 1
    • 80052798438 scopus 로고    scopus 로고
    • Arsenic exposure and toxicology: a historical perspective
    • PID: 21750349, COI: 1:CAS:528:DC%2BC3MXht1eiu7jM
    • Hughes MF et al. Arsenic exposure and toxicology: a historical perspective. Toxicol Sci. 2011;123(2):305–32.
    • (2011) Toxicol Sci , vol.123 , Issue.2 , pp. 305-332
    • Hughes, M.F.1
  • 2
    • 84874623639 scopus 로고    scopus 로고
    • The broad scope of health effects from chronic arsenic exposure: update on a worldwide public health problem
    • PID: 23458756
    • Naujokas MF et al. The broad scope of health effects from chronic arsenic exposure: update on a worldwide public health problem. Environ Health Perspect. 2013;121(3):295–302.
    • (2013) Environ Health Perspect , vol.121 , Issue.3 , pp. 295-302
    • Naujokas, M.F.1
  • 3
    • 84873469907 scopus 로고    scopus 로고
    • Arsenic and lead in juice: apple, citrus, and apple-base
    • PID: 23270108, COI: 1:CAS:528:DC%2BC3sXpt1Oitg%3D%3D, quiz 44
    • Wilson D, Hooper C, Shi X. Arsenic and lead in juice: apple, citrus, and apple-base. J Environ Health. 2012;75(5):14–20. quiz 44.
    • (2012) J Environ Health , vol.75 , Issue.5 , pp. 14-20
    • Wilson, D.1    Hooper, C.2    Shi, X.3
  • 4
    • 84897082954 scopus 로고    scopus 로고
    • Monomethylated trivalent arsenic species disrupt steroid receptor interactions with their DNA response elements at non-cytotoxic cellular concentrations
    • Gosse JA et al. Monomethylated trivalent arsenic species disrupt steroid receptor interactions with their DNA response elements at non-cytotoxic cellular concentrations. J Appl Toxicol. 2013. doi:10.1002/jat.2898.
    • (2013) J Appl Toxicol
    • Gosse, J.A.1
  • 5
    • 0042984067 scopus 로고    scopus 로고
    • Methylated trivalent arsenicals as candidate ultimate genotoxic forms of arsenic: induction of chromosomal mutations but not gene mutations
    • PID: 14556226, COI: 1:CAS:528:DC%2BD3sXovVyhsrw%3D
    • Kligerman AD et al. Methylated trivalent arsenicals as candidate ultimate genotoxic forms of arsenic: induction of chromosomal mutations but not gene mutations. Environ Mol Mutagen. 2003;42(3):192–205.
    • (2003) Environ Mol Mutagen , vol.42 , Issue.3 , pp. 192-205
    • Kligerman, A.D.1
  • 6
    • 84878732954 scopus 로고    scopus 로고
    • Metabolism of arsenic and its toxicological relevance
    • PID: 22811022, COI: 1:CAS:528:DC%2BC38XhtVCltb%2FO
    • Watanabe T, Hirano S. Metabolism of arsenic and its toxicological relevance. Arch Toxicol. 2013;87(6):969–79.
    • (2013) Arch Toxicol , vol.87 , Issue.6 , pp. 969-979
    • Watanabe, T.1    Hirano, S.2
  • 7
    • 61849150503 scopus 로고    scopus 로고
    • Effects of monomethylarsonic and monomethylarsonous acid on evoked synaptic potentials in hippocampal slices of adult and young rats
    • PID: 19371632
    • Kruger K et al. Effects of monomethylarsonic and monomethylarsonous acid on evoked synaptic potentials in hippocampal slices of adult and young rats. Toxicol Appl Pharmacol. 2009;236(1):115–23.
    • (2009) Toxicol Appl Pharmacol , vol.236 , Issue.1 , pp. 115-123
    • Kruger, K.1
  • 8
    • 79951626060 scopus 로고    scopus 로고
    • Arsenic toxicity in mammals and aquatic animals: a comparative biochemical approach
    • PID: 21112631, COI: 1:CAS:528:DC%2BC3MXisF2itr8%3D
    • Ventura-Lima J, Bogo MR, Monserrat JM. Arsenic toxicity in mammals and aquatic animals: a comparative biochemical approach. Ecotoxicol Environ Saf. 2011;74(3):211–8.
    • (2011) Ecotoxicol Environ Saf , vol.74 , Issue.3 , pp. 211-218
    • Ventura-Lima, J.1    Bogo, M.R.2    Monserrat, J.M.3
  • 9
    • 77953622000 scopus 로고    scopus 로고
    • Arsenic species, AS3MT amount, and AS3MT gene expression in different brain regions of mouse exposed to arsenite
    • PID: 20138265, COI: 1:CAS:528:DC%2BC3cXntlWqtL8%3D
    • Sanchez-Pena LC et al. Arsenic species, AS3MT amount, and AS3MT gene expression in different brain regions of mouse exposed to arsenite. Environ Res. 2010;110(5):428–34.
    • (2010) Environ Res , vol.110 , Issue.5 , pp. 428-434
    • Sanchez-Pena, L.C.1
  • 10
    • 67749124270 scopus 로고    scopus 로고
    • Effects of arsenic on maternal and fetal health
    • PID: 19575603, COI: 1:CAS:528:DC%2BD1MXht1art77N
    • Vahter M. Effects of arsenic on maternal and fetal health. Annu Rev Nutr. 2009;29:381–99.
    • (2009) Annu Rev Nutr , vol.29 , pp. 381-399
    • Vahter, M.1
  • 11
    • 34547915936 scopus 로고    scopus 로고
    • Arsenic exposure in pregnant mice disrupts placental vasculogenesis and causes spontaneous abortion
    • PID: 17569693, COI: 1:CAS:528:DC%2BD2sXpt1CitLo%3D
    • He W et al. Arsenic exposure in pregnant mice disrupts placental vasculogenesis and causes spontaneous abortion. Toxicol Sci. 2007;99(1):244–53.
    • (2007) Toxicol Sci , vol.99 , Issue.1 , pp. 244-253
    • He, W.1
  • 12
    • 79955874467 scopus 로고    scopus 로고
    • Arsenic-associated oxidative stress, inflammation, and immune disruption in human placenta and cord blood
    • PID: 20940111, COI: 1:CAS:528:DC%2BC3MXivVagsrw%3D
    • Ahmed S et al. Arsenic-associated oxidative stress, inflammation, and immune disruption in human placenta and cord blood. Environ Health Perspect. 2011;119(2):258–64.
    • (2011) Environ Health Perspect , vol.119 , Issue.2 , pp. 258-264
    • Ahmed, S.1
  • 13
    • 84876870433 scopus 로고    scopus 로고
    • Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: a systematic review and meta-analysis
    • PID: 23570911, COI: 1:CAS:528:DC%2BC3sXms1eqtbc%3D, Comprehensive meta-analysis of research focusing on the impact of arsenic exposure on intellegence (IQ) children
    • Rodriguez-Barranco M et al. Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: a systematic review and meta-analysis. Sci Total Environ. 2013;454-455:562–77. Comprehensive meta-analysis of research focusing on the impact of arsenic exposure on intellegence (IQ) in children.
    • (2013) Sci Total Environ , vol.454-455 , pp. 562-577
    • Rodriguez-Barranco, M.1
  • 14
    • 34748813747 scopus 로고    scopus 로고
    • Arsenic exposure and cognitive performance in Mexican schoolchildren
    • PID: 17805430, COI: 1:CAS:528:DC%2BD2sXhtFamsr%2FN
    • Rosado JL et al. Arsenic exposure and cognitive performance in Mexican schoolchildren. Environ Health Perspect. 2007;115(9):1371–5.
    • (2007) Environ Health Perspect , vol.115 , Issue.9 , pp. 1371-1375
    • Rosado, J.L.1
  • 15
    • 79958295533 scopus 로고    scopus 로고
    • Association between arsenic exposure and behavior among first-graders from Torreon, Mexico
    • PID: 21439564, COI: 1:CAS:528:DC%2BC3MXnsVWmsL8%3D
    • Roy A et al. Association between arsenic exposure and behavior among first-graders from Torreon, Mexico. Environ Res. 2011;111(5):670–6.
    • (2011) Environ Res , vol.111 , Issue.5 , pp. 670-676
    • Roy, A.1
  • 16
    • 33845806429 scopus 로고    scopus 로고
    • Children's intellectual function in relation to arsenic exposure
    • von Ehrenstein OS et al. Children's intellectual function in relation to arsenic exposure. Epidemiology. 2007;18(1):44–51.
    • (2007) Epidemiology , vol.18 , Issue.1 , pp. 44-51
    • von Ehrenstein, O.S.1
  • 17
    • 4644346389 scopus 로고    scopus 로고
    • Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh
    • PID: 15345348, COI: 1:CAS:528:DC%2BD2cXpvF2ru7c%3D
    • Wasserman GA et al. Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect. 2004;112(13):1329–33.
    • (2004) Environ Health Perspect , vol.112 , Issue.13 , pp. 1329-1333
    • Wasserman, G.A.1
  • 18
    • 34247111491 scopus 로고    scopus 로고
    • Arsenic and fluoride exposure in drinking water: children's IQ and growth in Shanyin county, Shanxi province, China
    • PID: 17450237, COI: 1:CAS:528:DC%2BD2sXltVKlsLs%3D
    • Wang SX et al. Arsenic and fluoride exposure in drinking water: children's IQ and growth in Shanyin county, Shanxi province, China. Environ Health Perspect. 2007;115(4):643–7.
    • (2007) Environ Health Perspect , vol.115 , Issue.4 , pp. 643-647
    • Wang, S.X.1
  • 19
    • 84880765366 scopus 로고    scopus 로고
    • Gender differences in the neurotoxicity of metals in children
    • PID: 23632092, COI: 1:CAS:528:DC%2BC3sXot1Cnsbs%3D
    • Llop S et al. Gender differences in the neurotoxicity of metals in children. Toxicology. 2013;311(1–2):3–12.
    • (2013) Toxicology , vol.311 , Issue.1-2 , pp. 3-12
    • Llop, S.1
  • 20
    • 84875596512 scopus 로고    scopus 로고
    • Environmental exposure to metals and children's growth to age 5 years: a prospective cohort study
    • PID: 23676282
    • Gardner RM et al. Environmental exposure to metals and children's growth to age 5 years: a prospective cohort study. Am J Epidemiol. 2013;177(12):1356–67.
    • (2013) Am J Epidemiol , vol.177 , Issue.12 , pp. 1356-1367
    • Gardner, R.M.1
  • 21
    • 74149094449 scopus 로고    scopus 로고
    • Effects of arsenic in drinking water on children's intelligence
    • PID: 17712958, COI: 1:CAS:528:DC%2BD2sXht1ent7jJ
    • Kang J et al. Effects of arsenic in drinking water on children's intelligence. Wei Sheng Yan Jiu. 2007;36(3):347–9.
    • (2007) Wei Sheng Yan Jiu , vol.36 , Issue.3 , pp. 347-349
    • Kang, J.1
  • 22
    • 38449122632 scopus 로고    scopus 로고
    • Developmental impacts of heavy metals and undernutrition
    • PID: 18226076, COI: 1:CAS:528:DC%2BD1cXhvF2gsbk%3D
    • Wasserman GA et al. Developmental impacts of heavy metals and undernutrition. Basic Clin Pharmacol Toxicol. 2008;102(2):212–7.
    • (2008) Basic Clin Pharmacol Toxicol , vol.102 , Issue.2 , pp. 212-217
    • Wasserman, G.A.1
  • 23
    • 84873992179 scopus 로고    scopus 로고
    • Association of cord blood levels of lead, arsenic, and zinc with neurodevelopmental indicators in newborns: a birth cohort study in Chitwan Valley, Nepal
    • PID: 23164520, COI: 1:CAS:528:DC%2BC38Xhs12ks7%2FL
    • Parajuli RP et al. Association of cord blood levels of lead, arsenic, and zinc with neurodevelopmental indicators in newborns: a birth cohort study in Chitwan Valley, Nepal. Environ Res. 2013;121:45–51.
    • (2013) Environ Res , vol.121 , pp. 45-51
    • Parajuli, R.P.1
  • 24
    • 77955567204 scopus 로고    scopus 로고
    • Pre- and postnatal arsenic exposure and child development at 18 months of age: a cohort study in rural Bangladesh
    • PID: 20085967
    • Hamadani JD et al. Pre- and postnatal arsenic exposure and child development at 18 months of age: a cohort study in rural Bangladesh. Int J Epidemiol. 2010;39(5):1206–16.
    • (2010) Int J Epidemiol , vol.39 , Issue.5 , pp. 1206-1216
    • Hamadani, J.D.1
  • 25
    • 60749116389 scopus 로고    scopus 로고
    • Effect of arsenic exposure during pregnancy on infant development at 7 months in rural Matlab, Bangladesh
    • PID: 19270801, COI: 1:CAS:528:DC%2BD1MXivFSkt7s%3D
    • Tofail F et al. Effect of arsenic exposure during pregnancy on infant development at 7 months in rural Matlab, Bangladesh. Environ Health Perspect. 2009;117(2):288–93.
    • (2009) Environ Health Perspect , vol.117 , Issue.2 , pp. 288-293
    • Tofail, F.1
  • 26
    • 83455205972 scopus 로고    scopus 로고
    • Critical windows of exposure for arsenic-associated impairment of cognitive function in pre-school girls and boys: a population-based cohort study
    • PID: 22158669, COI: 1:STN:280:DC%2BC38%2FntFKhsg%3D%3D, In-depth study focusing on maternal and early childhood exposure to arsenic; demonstrates differential effect of arsenic on sex and cognition
    • Hamadani JD et al. Critical windows of exposure for arsenic-associated impairment of cognitive function in pre-school girls and boys: a population-based cohort study. Int J Epidemiol. 2011;40(6):1593–604. In-depth study focusing on maternal and early childhood exposure to arsenic; demonstrates differential effect of arsenic on sex and cognition.
    • (2011) Int J Epidemiol , vol.40 , Issue.6 , pp. 1593-1604
    • Hamadani, J.D.1
  • 27
    • 0042737426 scopus 로고    scopus 로고
    • The effects of chronic arsenic exposure from drinking water on the neurobehavioral development in adolescence
    • PID: 12900089, COI: 1:CAS:528:DC%2BD3sXlvFGit78%3D
    • Tsai SY et al. The effects of chronic arsenic exposure from drinking water on the neurobehavioral development in adolescence. Neurotoxicology. 2003;24(4–5):747–53.
    • (2003) Neurotoxicology , vol.24 , Issue.4-5 , pp. 747-753
    • Tsai, S.Y.1
  • 28
    • 32344441585 scopus 로고    scopus 로고
    • Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site
    • PID: 16310252, COI: 1:CAS:528:DC%2BD28XhtlCksLg%3D
    • Wright RO et al. Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology. 2006;27(2):210–6.
    • (2006) Neurotoxicology , vol.27 , Issue.2 , pp. 210-216
    • Wright, R.O.1
  • 29
    • 0037732662 scopus 로고    scopus 로고
    • Hair analysis: exploring the state of the science
    • PID: 12676618, COI: 1:CAS:528:DC%2BD3sXjtlKrsr8%3D
    • Harkins DK, Susten AS. Hair analysis: exploring the state of the science. Environ Health Perspect. 2003;111(4):576–8.
    • (2003) Environ Health Perspect , vol.111 , Issue.4 , pp. 576-578
    • Harkins, D.K.1    Susten, A.S.2
  • 30
    • 33847081710 scopus 로고    scopus 로고
    • Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh
    • PID: 17384779, COI: 1:CAS:528:DC%2BD2sXisFalsrY%3D
    • Wasserman GA et al. Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh. Environ Health Perspect. 2007;115(2):285–9.
    • (2007) Environ Health Perspect , vol.115 , Issue.2 , pp. 285-289
    • Wasserman, G.A.1
  • 31
    • 78549247841 scopus 로고    scopus 로고
    • Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: synergistic action of metal mixture in glial and neuronal functions
    • PID: 20829427, COI: 1:CAS:528:DC%2BC3cXhsVKjsbfK
    • Rai A et al. Characterization of developmental neurotoxicity of As, Cd, and Pb mixture: synergistic action of metal mixture in glial and neuronal functions. Toxicol Sci. 2010;118(2):586–601.
    • (2010) Toxicol Sci , vol.118 , Issue.2 , pp. 586-601
    • Rai, A.1
  • 32
    • 48649108002 scopus 로고    scopus 로고
    • Metal concentrations in rural topsoil in South Carolina: potential for human health impact
    • PID: 18538375, COI: 1:CAS:528:DC%2BD1cXps1emu7k%3D
    • Aelion CM et al. Metal concentrations in rural topsoil in South Carolina: potential for human health impact. Sci Total Environ. 2008;402(2–3):149–56.
    • (2008) Sci Total Environ , vol.402 , Issue.2-3 , pp. 149-156
    • Aelion, C.M.1
  • 33
    • 79956079770 scopus 로고    scopus 로고
    • Probability of intellectual disability is associated with soil concentrations of arsenic and lead
    • PID: 21450328, COI: 1:CAS:528:DC%2BC3MXmsVynsr4%3D
    • McDermott S et al. Probability of intellectual disability is associated with soil concentrations of arsenic and lead. Chemosphere. 2011;84(1):31–8.
    • (2011) Chemosphere , vol.84 , Issue.1 , pp. 31-38
    • McDermott, S.1
  • 34
    • 79955564520 scopus 로고    scopus 로고
    • Arsenic and manganese exposure and children's intellectual function
    • PID: 21453724, COI: 1:CAS:528:DC%2BC3MXntFGrur4%3D
    • Wasserman GA et al. Arsenic and manganese exposure and children's intellectual function. Neurotoxicology. 2011;32(4):450–7.
    • (2011) Neurotoxicology , vol.32 , Issue.4 , pp. 450-457
    • Wasserman, G.A.1
  • 35
    • 80052716111 scopus 로고    scopus 로고
    • Socioeconomic differences and the impact of being small for gestational age on neurodevelopment among preschool-aged children
    • PID: 22206199
    • Drews-Botsch C et al. Socioeconomic differences and the impact of being small for gestational age on neurodevelopment among preschool-aged children. Rev Environ Health. 2011;26(3):221–9.
    • (2011) Rev Environ Health , vol.26 , Issue.3 , pp. 221-229
    • Drews-Botsch, C.1
  • 36
    • 67650498951 scopus 로고    scopus 로고
    • The association between arsenic and children's intelligence: a meta-analysis
    • PID: 19107329, COI: 1:CAS:528:DC%2BD1MXmtF2ktro%3D
    • Dong J, Su SY. The association between arsenic and children's intelligence: a meta-analysis. Biol Trace Elem Res. 2009;129(1–3):88–93.
    • (2009) Biol Trace Elem Res , vol.129 , Issue.1-3 , pp. 88-93
    • Dong, J.1    Su, S.Y.2
  • 37
    • 37349100122 scopus 로고    scopus 로고
    • Decreased intelligence in children and exposure to fluoride and arsenic in drinking water
    • PID: 18038039
    • Rocha-Amador D et al. Decreased intelligence in children and exposure to fluoride and arsenic in drinking water. Cad Saude Publica. 2007;23 Suppl 4:S579–87.
    • (2007) Cad Saude Publica , vol.23 , pp. S579-S587
    • Rocha-Amador, D.1
  • 38
    • 0038670759 scopus 로고    scopus 로고
    • Iron deficiency alters brain development and functioning
    • PID: 12730445, COI: 1:CAS:528:DC%2BD3sXjs1Oqsrs%3D
    • Beard J. Iron deficiency alters brain development and functioning. J Nutr. 2003;133(5 Suppl 1):1468S–72.
    • (2003) J Nutr , vol.133 , pp. 1468S-1472
    • Beard, J.1
  • 39
    • 38049145891 scopus 로고    scopus 로고
    • Arsenic exposure and anemia in Bangladesh: a population-based study
    • PID: 18188085, COI: 1:CAS:528:DC%2BD1cXhsFyisQ%3D%3D
    • Heck JE et al. Arsenic exposure and anemia in Bangladesh: a population-based study. J Occup Environ Med. 2008;50(1):80–7.
    • (2008) J Occup Environ Med , vol.50 , Issue.1 , pp. 80-87
    • Heck, J.E.1
  • 40
    • 84878409215 scopus 로고    scopus 로고
    • DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women
    • PID: 23576045, COI: 1:CAS:528:DC%2BC3sXoslyqtrc%3D
    • Dominguez-Salas P et al. DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr. 2013;97(6):1217–27.
    • (2013) Am J Clin Nutr , vol.97 , Issue.6 , pp. 1217-1227
    • Dominguez-Salas, P.1
  • 41
    • 60749105001 scopus 로고    scopus 로고
    • Dietary intake of methionine, cysteine, and protein and urinary arsenic excretion in Bangladesh
    • PID: 19165394, COI: 1:CAS:528:DC%2BD1MXhvV2nt7c%3D
    • Heck JE et al. Dietary intake of methionine, cysteine, and protein and urinary arsenic excretion in Bangladesh. Environ Health Perspect. 2009;117(1):99–104.
    • (2009) Environ Health Perspect , vol.117 , Issue.1 , pp. 99-104
    • Heck, J.E.1
  • 42
    • 0035113197 scopus 로고    scopus 로고
    • Exposure to arsenic and lead and neuropsychological development in Mexican children
    • PID: 11161656, COI: 1:CAS:528:DC%2BD3MXptlemsw%3D%3D
    • Calderon J et al. Exposure to arsenic and lead and neuropsychological development in Mexican children. Environ Res. 2001;85(2):69–76.
    • (2001) Environ Res , vol.85 , Issue.2 , pp. 69-76
    • Calderon, J.1
  • 43
    • 79953268839 scopus 로고    scopus 로고
    • Long-term low-level arsenic exposure is associated with poorer neuropsychological functioning: a Project FRONTIER study
    • PID: 21556183, Important study demonstrating the inverse relationship between cumulative arsenic exposure and adult cognition; however, arsenic assessments were conducted using GIS software instead of direct analysis
    • O'Bryant SE et al. Long-term low-level arsenic exposure is associated with poorer neuropsychological functioning: a Project FRONTIER study. Int J Environ Res Public Health. 2011;8(3):861–74. Important study demonstrating the inverse relationship between cumulative arsenic exposure and adult cognition; however, arsenic assessments were conducted using GIS software instead of direct analysis.
    • (2011) Int J Environ Res Public Health , vol.8 , Issue.3 , pp. 861-874
    • O'Bryant, S.E.1
  • 44
    • 80052711268 scopus 로고    scopus 로고
    • Low-level groundwater arsenic exposure impacts cognition: a project FRONTIER study
    • PID: 21949980, COI: 1:CAS:528:DC%2BC3MXht1GktrzM, Interesting study from the the United States demonstating the association between very low arsenic exposure (10 ppb on par with EPA standards) and impaired cognitive function adults
    • Gong G et al. Low-level groundwater arsenic exposure impacts cognition: a project FRONTIER study. J Environ Health. 2011;74(2):16–22. Interesting study from the the United States demonstating the association between very low arsenic exposure (10 ppb on par with EPA standards) and impaired cognitive function in adults.
    • (2011) J Environ Health , vol.74 , Issue.2 , pp. 16-22
    • Gong, G.1
  • 45
    • 33750317408 scopus 로고    scopus 로고
    • The relation of education and gender on the attention items of the Mini-Mental State Examination in Spanish speaking Hispanic elders
    • PID: 16968662
    • Rosselli M et al. The relation of education and gender on the attention items of the Mini-Mental State Examination in Spanish speaking Hispanic elders. Arch Clin Neuropsychol. 2006;21(7):677–86.
    • (2006) Arch Clin Neuropsychol , vol.21 , Issue.7 , pp. 677-686
    • Rosselli, M.1
  • 46
    • 75149195766 scopus 로고    scopus 로고
    • The Mini-mental State Examination revisited: ceiling and floor effects after score adjustment for educational level in an aging Mexican population
    • PID: 19735592
    • Franco-Marina F et al. The Mini-mental State Examination revisited: ceiling and floor effects after score adjustment for educational level in an aging Mexican population. Int Psychogeriatr. 2010;22(1):72–81.
    • (2010) Int Psychogeriatr , vol.22 , Issue.1 , pp. 72-81
    • Franco-Marina, F.1
  • 47
    • 84867647107 scopus 로고    scopus 로고
    • Quality of life and mental health status of arsenic-affected patients in a Bangladeshi population
    • PID: 23082628
    • Syed EH et al. Quality of life and mental health status of arsenic-affected patients in a Bangladeshi population. J Health Popul Nutr. 2012;30(3):262–9.
    • (2012) J Health Popul Nutr , vol.30 , Issue.3 , pp. 262-269
    • Syed, E.H.1
  • 48
    • 57749186630 scopus 로고    scopus 로고
    • Arsenic pollution sources
    • PID: 18982996, COI: 1:CAS:528:DC%2BD1cXhsVGgtb3F
    • Garelick H et al. Arsenic pollution sources. Rev Environ Contam Toxicol. 2008;197:17–60.
    • (2008) Rev Environ Contam Toxicol , vol.197 , pp. 17-60
    • Garelick, H.1
  • 49
    • 35448933247 scopus 로고    scopus 로고
    • Chronic arsenic poisoning in drinking water in Inner Mongolia and its associated health effects
    • PID: 17952786, COI: 1:CAS:528:DC%2BD2sXhtFykur%2FO
    • Guo JX et al. Chronic arsenic poisoning in drinking water in Inner Mongolia and its associated health effects. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2007;42(12):1853–8.
    • (2007) J Environ Sci Health A Tox Hazard Subst Environ Eng , vol.42 , Issue.12 , pp. 1853-1858
    • Guo, J.X.1
  • 50
    • 84862833367 scopus 로고    scopus 로고
    • Investigation on mental health of residents living in a mineral area in Hubei province
    • PID: 19358753, COI: 1:CAS:528:DC%2BD1MXhtVGlurvO
    • Dang WM et al. Investigation on mental health of residents living in a mineral area in Hubei province. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008;26(8):457–60.
    • (2008) Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi , vol.26 , Issue.8 , pp. 457-460
    • Dang, W.M.1
  • 51
    • 4143131028 scopus 로고    scopus 로고
    • Mental health burden amongst inhabitants of an arsenic-affected area in Inner Mongolia, China
    • PID: 15312930
    • Fujino Y et al. Mental health burden amongst inhabitants of an arsenic-affected area in Inner Mongolia, China. Soc Sci Med. 2004;59(9):1969–73.
    • (2004) Soc Sci Med , vol.59 , Issue.9 , pp. 1969-1973
    • Fujino, Y.1
  • 52
    • 84877027839 scopus 로고    scopus 로고
    • Arsenicosis: is it a protective or predisposing factor for mental illness?
    • PID: 23408762
    • Sen D, Sarathi Biswas P. Arsenicosis: is it a protective or predisposing factor for mental illness? Iran J Psychiatry. 2012;7(4):180–3.
    • (2012) Iran J Psychiatry , vol.7 , Issue.4 , pp. 180-183
    • Sen, D.1    Sarathi Biswas, P.2
  • 53
    • 7244221544 scopus 로고    scopus 로고
    • Prevalence of chronic diseases in adults exposed to arsenic-contaminated drinking water
    • PID: 15514231
    • Zierold KM, Knobeloch L, Anderson H. Prevalence of chronic diseases in adults exposed to arsenic-contaminated drinking water. Am J Public Health. 2004;94(11):1936–7.
    • (2004) Am J Public Health , vol.94 , Issue.11 , pp. 1936-1937
    • Zierold, K.M.1    Knobeloch, L.2    Anderson, H.3
  • 54
    • 79952572698 scopus 로고    scopus 로고
    • Impact of early developmental arsenic exposure on promotor CpG-island methylation of genes involved in neuronal plasticity
    • PID: 21300125, COI: 1:CAS:528:DC%2BC3MXjtFCgurY%3D, First study to demonstrate the impact of arsenic on DNA methylation genes associated with neuronal plasticity
    • Martinez L et al. Impact of early developmental arsenic exposure on promotor CpG-island methylation of genes involved in neuronal plasticity. Neurochem Int. 2011;58(5):574–81. First study to demonstrate the impact of arsenic on DNA methylation in genes associated with neuronal plasticity.
    • (2011) Neurochem Int , vol.58 , Issue.5 , pp. 574-581
    • Martinez, L.1
  • 55
    • 33751427435 scopus 로고    scopus 로고
    • Long term low-dose arsenic exposure induces loss of DNA methylation
    • PID: 17107663, COI: 1:CAS:528:DC%2BD28Xht1Oht7rE
    • Reichard JF, Schnekenburger M, Puga A. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochem Biophys Res Commun. 2007;352(1):188–92.
    • (2007) Biochem Biophys Res Commun , vol.352 , Issue.1 , pp. 188-192
    • Reichard, J.F.1    Schnekenburger, M.2    Puga, A.3
  • 56
    • 84874022257 scopus 로고    scopus 로고
    • Arsenic and the epigenome: interindividual differences in arsenic metabolism related to distinct patterns of DNA methylation
    • PID: 23315758, COI: 1:CAS:528:DC%2BC3sXnt1WrsA%3D%3D
    • Bailey KA et al. Arsenic and the epigenome: interindividual differences in arsenic metabolism related to distinct patterns of DNA methylation. J Biochem Mol Toxicol. 2013;27(2):106–15.
    • (2013) J Biochem Mol Toxicol , vol.27 , Issue.2 , pp. 106-115
    • Bailey, K.A.1
  • 57
    • 84863423870 scopus 로고    scopus 로고
    • Prenatal arsenic exposure and DNA methylation in maternal and umbilical cord blood leukocytes
    • PID: 22466225, COI: 1:CAS:528:DC%2BC38Xht1Sht7fP
    • Kile ML et al. Prenatal arsenic exposure and DNA methylation in maternal and umbilical cord blood leukocytes. Environ Health Perspect. 2012;120(7):1061–6.
    • (2012) Environ Health Perspect , vol.120 , Issue.7 , pp. 1061-1066
    • Kile, M.L.1
  • 58
    • 84881010102 scopus 로고    scopus 로고
    • Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero
    • PID: 23757598
    • Koestler DC et al. Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero. Environ Health Perspect. 2013;121(8):971–7.
    • (2013) Environ Health Perspect , vol.121 , Issue.8 , pp. 971-977
    • Koestler, D.C.1
  • 59
    • 77954107743 scopus 로고    scopus 로고
    • Effects of arsenic exposure on DNA methylation and epigenetic gene regulation
    • PID: 20514360, COI: 1:CAS:528:DC%2BC3cXhs1ygsb8%3D
    • Reichard JF, Puga A. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics. 2010;2(1):87–104.
    • (2010) Epigenomics , vol.2 , Issue.1 , pp. 87-104
    • Reichard, J.F.1    Puga, A.2
  • 60
    • 84871302953 scopus 로고    scopus 로고
    • Associations between arsenic exposure and global posttranslational histone modifications among adults in Bangladesh
    • PID: 23064002, COI: 1:CAS:528:DC%2BC38XhvVSqu7%2FM
    • Chervona Y et al. Associations between arsenic exposure and global posttranslational histone modifications among adults in Bangladesh. Cancer Epidemiol Biomarkers Prev. 2012;21(12):2252–60.
    • (2012) Cancer Epidemiol Biomarkers Prev , vol.21 , Issue.12 , pp. 2252-2260
    • Chervona, Y.1
  • 61
    • 61849137246 scopus 로고    scopus 로고
    • Effects of nickel, chromate, and arsenite on histone 3 lysine methylation
    • PID: 19371620, COI: 1:CAS:528:DC%2BD1MXjtFKqtLg%3D
    • Zhou X et al. Effects of nickel, chromate, and arsenite on histone 3 lysine methylation. Toxicol Appl Pharmacol. 2009;236(1):78–84.
    • (2009) Toxicol Appl Pharmacol , vol.236 , Issue.1 , pp. 78-84
    • Zhou, X.1
  • 62
    • 49649083174 scopus 로고    scopus 로고
    • Arsenite alters global histone H3 methylation
    • PID: 18321869, COI: 1:CAS:528:DC%2BD1cXhtV2jsL3O
    • Zhou X et al. Arsenite alters global histone H3 methylation. Carcinogenesis. 2008;29(9):1831–6.
    • (2008) Carcinogenesis , vol.29 , Issue.9 , pp. 1831-1836
    • Zhou, X.1
  • 63
    • 84873561362 scopus 로고    scopus 로고
    • Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic
    • PID: 23405071, COI: 1:CAS:528:DC%2BC3sXjtVSrsrs%3D
    • Cronican AA et al. Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic. PLoS One. 2013;8(2):e53478.
    • (2013) PLoS One , vol.8 , Issue.2
    • Cronican, A.A.1
  • 64
    • 74249091395 scopus 로고    scopus 로고
    • Decreased arginine methylation and myelin alterations in arsenic exposed rats
    • PID: 19896975, COI: 1:CAS:528:DC%2BC3cXhtVKjtrk%3D
    • Zarazua S et al. Decreased arginine methylation and myelin alterations in arsenic exposed rats. Neurotoxicology. 2010;31(1):94–100.
    • (2010) Neurotoxicology , vol.31 , Issue.1 , pp. 94-100
    • Zarazua, S.1
  • 65
    • 79959544817 scopus 로고    scopus 로고
    • Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs
    • PID: 21550982, COI: 1:CAS:528:DC%2BC3MXnvFekurw%3D
    • Zhou X et al. Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs. J Biol Chem. 2011;286(26):22855–63.
    • (2011) J Biol Chem , vol.286 , Issue.26 , pp. 22855-22863
    • Zhou, X.1
  • 66
    • 84884706358 scopus 로고    scopus 로고
    • Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors
    • PID: 23921152, COI: 1:CAS:528:DC%2BC3sXhslKqsrbL
    • Sharma B, Sharma PM. Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. Toxicol Appl Pharmacol. 2013;273(1):180–8.
    • (2013) Toxicol Appl Pharmacol , vol.273 , Issue.1 , pp. 180-188
    • Sharma, B.1    Sharma, P.M.2
  • 67
    • 72049115766 scopus 로고    scopus 로고
    • Learning deficits in C57BL/6 J mice following perinatal arsenic exposure: consequence of lower corticosterone receptor levels?
    • PID: 19751756, COI: 1:CAS:528:DC%2BD1MXht1yjtbvJ
    • Martinez-Finley EJ, Ali AM, Allan AM. Learning deficits in C57BL/6 J mice following perinatal arsenic exposure: consequence of lower corticosterone receptor levels? Pharmacol Biochem Behav. 2009;94(2):271–7.
    • (2009) Pharmacol Biochem Behav , vol.94 , Issue.2 , pp. 271-277
    • Martinez-Finley, E.J.1    Ali, A.M.2    Allan, A.M.3
  • 68
    • 84867231252 scopus 로고    scopus 로고
    • Changes in the synaptic structure of hippocampal neurons and impairment of spatial memory in a rat model caused by chronic arsenite exposure
    • PID: 22824511, COI: 1:CAS:528:DC%2BC38XhsFSrtrfM
    • Jing J et al. Changes in the synaptic structure of hippocampal neurons and impairment of spatial memory in a rat model caused by chronic arsenite exposure. Neurotoxicology. 2012;33(5):1230–8.
    • (2012) Neurotoxicology , vol.33 , Issue.5 , pp. 1230-1238
    • Jing, J.1
  • 69
    • 67650729374 scopus 로고    scopus 로고
    • Behavioral and neurotoxic effects of arsenic exposure in zebrafish (Danio rerio, Teleostei: Cyprinidae)
    • PID: 19501674
    • de Castro MR et al. Behavioral and neurotoxic effects of arsenic exposure in zebrafish (Danio rerio, Teleostei: Cyprinidae). Comp Biochem Physiol C Toxicol Pharmacol. 2009;150(3):337–42.
    • (2009) Comp Biochem Physiol C Toxicol Pharmacol , vol.150 , Issue.3 , pp. 337-342
    • de Castro, M.R.1
  • 70
    • 33745221174 scopus 로고    scopus 로고
    • Effects of arsenite on long-term potentiation in hippocampal slices from young and adult rats
    • PID: 16677784
    • Kruger K et al. Effects of arsenite on long-term potentiation in hippocampal slices from young and adult rats. Toxicol Lett. 2006;165(2):167–73.
    • (2006) Toxicol Lett , vol.165 , Issue.2 , pp. 167-173
    • Kruger, K.1
  • 71
    • 58149293407 scopus 로고    scopus 로고
    • Effects of arsenic exposure from drinking water on spatial memory, ultra-structures and NMDAR gene expression of hippocampus in rats
    • PID: 19041379, COI: 1:CAS:528:DC%2BD1MXntlOgug%3D%3D
    • Luo JH et al. Effects of arsenic exposure from drinking water on spatial memory, ultra-structures and NMDAR gene expression of hippocampus in rats. Toxicol Lett. 2009;184(2):121–5.
    • (2009) Toxicol Lett , vol.184 , Issue.2 , pp. 121-125
    • Luo, J.H.1
  • 72
    • 84883395170 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis and mRNA expression are altered by perinatal arsenic exposure in mice and restored by brief exposure to enrichment
    • PID: 24019935, COI: 1:CAS:528:DC%2BC3sXhsVCku7nF
    • Tyler CR, Allan AM. Adult hippocampal neurogenesis and mRNA expression are altered by perinatal arsenic exposure in mice and restored by brief exposure to enrichment. PLoS One. 2013;8(9):e73720.
    • (2013) PLoS One , vol.8 , Issue.9
    • Tyler, C.R.1    Allan, A.M.2
  • 73
    • 84859073124 scopus 로고    scopus 로고
    • Arsenite exposure altered the expression of NMDA receptor and postsynaptic signaling proteins in rat hippocampus
    • PID: 22421273, COI: 1:CAS:528:DC%2BC38XlvFyrt7w%3D
    • Luo JH et al. Arsenite exposure altered the expression of NMDA receptor and postsynaptic signaling proteins in rat hippocampus. Toxicol Lett. 2012;211(1):39–44.
    • (2012) Toxicol Lett , vol.211 , Issue.1 , pp. 39-44
    • Luo, J.H.1
  • 74
    • 46149101738 scopus 로고    scopus 로고
    • Moderate perinatal arsenic exposure alters neuroendocrine markers associated with depression and increases depressive-like behaviors in adult mouse offspring
    • PID: 18573533, COI: 1:CAS:528:DC%2BD1cXotlWqtLY%3D
    • Martinez EJ et al. Moderate perinatal arsenic exposure alters neuroendocrine markers associated with depression and increases depressive-like behaviors in adult mouse offspring. Neurotoxicology. 2008;29(4):647–55.
    • (2008) Neurotoxicology , vol.29 , Issue.4 , pp. 647-655
    • Martinez, E.J.1
  • 75
    • 33750615090 scopus 로고    scopus 로고
    • Zinc induces ERK-dependent cell death through a specific Ras isoform
    • PID: 17013754, COI: 1:CAS:528:DC%2BD28XhtFKmtr3F
    • Klein C et al. Zinc induces ERK-dependent cell death through a specific Ras isoform. Apoptosis. 2006;11(11):1933–44.
    • (2006) Apoptosis , vol.11 , Issue.11 , pp. 1933-1944
    • Klein, C.1
  • 76
    • 80053216876 scopus 로고    scopus 로고
    • Reduced expression of MAPK/ERK genes in perinatal arsenic-exposed offspring induced by glucocorticoid receptor deficits
    • PID: 21784148, COI: 1:CAS:528:DC%2BC3MXht1ejsbfP
    • Martinez-Finley EJ et al. Reduced expression of MAPK/ERK genes in perinatal arsenic-exposed offspring induced by glucocorticoid receptor deficits. Neurotoxicol Teratol. 2011;33(5):530–7.
    • (2011) Neurotoxicol Teratol , vol.33 , Issue.5 , pp. 530-537
    • Martinez-Finley, E.J.1
  • 77
    • 4344590003 scopus 로고    scopus 로고
    • Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain
    • PID: 15310238, COI: 1:CAS:528:DC%2BD2cXls1Kqtb0%3D
    • Bodwell JE, Kingsley LA, Hamilton JW. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chem Res Toxicol. 2004;17(8):1064–76.
    • (2004) Chem Res Toxicol , vol.17 , Issue.8 , pp. 1064-1076
    • Bodwell, J.E.1    Kingsley, L.A.2    Hamilton, J.W.3
  • 78
    • 33845893329 scopus 로고    scopus 로고
    • Arsenic disruption of steroid receptor gene activation: complex dose-response effects are shared by several steroid receptors
    • PID: 17173375, COI: 1:CAS:528:DC%2BD28Xht1Knu7fF
    • Bodwell JE et al. Arsenic disruption of steroid receptor gene activation: complex dose-response effects are shared by several steroid receptors. Chem Res Toxicol. 2006;19(12):1619–29.
    • (2006) Chem Res Toxicol , vol.19 , Issue.12 , pp. 1619-1629
    • Bodwell, J.E.1
  • 79
    • 34447542950 scopus 로고    scopus 로고
    • Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture
    • PID: 17283378, COI: 1:CAS:528:DC%2BD2sXntlKgt7Y%3D
    • Davey JC et al. Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture. Toxicol Sci. 2007;98(1):75–86.
    • (2007) Toxicol Sci , vol.98 , Issue.1 , pp. 75-86
    • Davey, J.C.1
  • 80
    • 84874611284 scopus 로고    scopus 로고
    • Systems biology and birth defects prevention: blockade of the glucocorticoid receptor prevents arsenic-induced birth defects
    • PID: 23458687, COI: 1:CAS:528:DC%2BC2cXkvVSgurY%3D
    • Ahir BK et al. Systems biology and birth defects prevention: blockade of the glucocorticoid receptor prevents arsenic-induced birth defects. Environ Health Perspect. 2013;121(3):332–8.
    • (2013) Environ Health Perspect , vol.121 , Issue.3 , pp. 332-338
    • Ahir, B.K.1
  • 81
    • 84867230578 scopus 로고    scopus 로고
    • Perinatal exposure to 50 ppb sodium arsenate induces hypothalamic-pituitary-adrenal axis dysregulation in male C57BL/6 mice
    • PID: 22960421, COI: 1:CAS:528:DC%2BC38XhsFSrt7zN, Comprehensive study assessing the impact of developmental exposure to arsenic on the GR and HPA adult mice
    • Goggin SL, Labrecque MT, Allan AM. Perinatal exposure to 50 ppb sodium arsenate induces hypothalamic-pituitary-adrenal axis dysregulation in male C57BL/6 mice. Neurotoxicology. 2012;33(5):1338–45. Comprehensive study assessing the impact of developmental exposure to arsenic on the GR and HPA in adult mice.
    • (2012) Neurotoxicology , vol.33 , Issue.5 , pp. 1338-1345
    • Goggin, S.L.1    Labrecque, M.T.2    Allan, A.M.3
  • 82
    • 0036852694 scopus 로고    scopus 로고
    • Effects of sodium arsenite exposure on development and behavior in the rat
    • PID: 12460656, COI: 1:CAS:528:DC%2BD38XptFertL0%3D
    • Rodriguez VM et al. Effects of sodium arsenite exposure on development and behavior in the rat. Neurotoxicol Teratol. 2002;24(6):743–50.
    • (2002) Neurotoxicol Teratol , vol.24 , Issue.6 , pp. 743-750
    • Rodriguez, V.M.1
  • 83
    • 68949211353 scopus 로고    scopus 로고
    • Chronic low-level arsenic exposure causes gender-specific alterations in locomotor activity, dopaminergic systems, and thioredoxin expression in mice
    • PID: 19121333, COI: 1:CAS:528:DC%2BD1MXhtVKksLjP
    • Bardullas U et al. Chronic low-level arsenic exposure causes gender-specific alterations in locomotor activity, dopaminergic systems, and thioredoxin expression in mice. Toxicol Appl Pharmacol. 2009;239(2):169–77.
    • (2009) Toxicol Appl Pharmacol , vol.239 , Issue.2 , pp. 169-177
    • Bardullas, U.1
  • 84
    • 78049461924 scopus 로고    scopus 로고
    • Chronic exposure to low levels of inorganic arsenic causes alterations in locomotor activity and in the expression of dopaminergic and antioxidant systems in the albino rat
    • PID: 20699118, COI: 1:CAS:528:DC%2BC3cXhtlyksbbK
    • Rodriguez VM et al. Chronic exposure to low levels of inorganic arsenic causes alterations in locomotor activity and in the expression of dopaminergic and antioxidant systems in the albino rat. Neurotoxicol Teratol. 2010;32(6):640–7.
    • (2010) Neurotoxicol Teratol , vol.32 , Issue.6 , pp. 640-647
    • Rodriguez, V.M.1
  • 85
    • 70350028185 scopus 로고    scopus 로고
    • Attenuation of arsenic neurotoxicity by curcumin in rats
    • PID: 19631675, COI: 1:CAS:528:DC%2BD1MXht1GmtbzJ
    • Yadav RS et al. Attenuation of arsenic neurotoxicity by curcumin in rats. Toxicol Appl Pharmacol. 2009;240(3):367–76.
    • (2009) Toxicol Appl Pharmacol , vol.240 , Issue.3 , pp. 367-376
    • Yadav, R.S.1
  • 86
    • 84881255311 scopus 로고    scopus 로고
    • Maternal and early life arsenite exposure impairs neurodevelopment and increases the expression of PSA-NCAM in hippocampus of rat offspring
    • PID: 23811142, COI: 1:CAS:528:DC%2BC3sXht12is7%2FP
    • Luo J et al. Maternal and early life arsenite exposure impairs neurodevelopment and increases the expression of PSA-NCAM in hippocampus of rat offspring. Toxicology. 2013;311(3):99–106.
    • (2013) Toxicology , vol.311 , Issue.3 , pp. 99-106
    • Luo, J.1
  • 87
    • 84856997520 scopus 로고    scopus 로고
    • Developmental and neurobehavioural toxicity study of arsenic on rats following gestational exposure
    • PID: 22670478, COI: 1:CAS:528:DC%2BC38XotFKitLw%3D
    • Gandhi DN, Panchal GM, Patel KG. Developmental and neurobehavioural toxicity study of arsenic on rats following gestational exposure. Indian J Exp Biol. 2012;50(2):147–55.
    • (2012) Indian J Exp Biol , vol.50 , Issue.2 , pp. 147-155
    • Gandhi, D.N.1    Panchal, G.M.2    Patel, K.G.3
  • 88
    • 84858749742 scopus 로고    scopus 로고
    • Arsenic alters behavioral parameters and brain ectonucleotidases activities in zebrafish (Danio rerio)
    • PID: 22265774, COI: 1:CAS:528:DC%2BC38Xhs1Cru74%3D
    • Baldissarelli LA et al. Arsenic alters behavioral parameters and brain ectonucleotidases activities in zebrafish (Danio rerio). Comp Biochem Physiol C Toxicol Pharmacol. 2012;155(4):566–72.
    • (2012) Comp Biochem Physiol C Toxicol Pharmacol , vol.155 , Issue.4 , pp. 566-572
    • Baldissarelli, L.A.1
  • 89
    • 80055098497 scopus 로고    scopus 로고
    • Neuroprotective efficacy of curcumin in arsenic induced cholinergic dysfunctions in rats
    • PID: 21839772, COI: 1:CAS:528:DC%2BC3MXhsVamsbrO
    • Yadav RS et al. Neuroprotective efficacy of curcumin in arsenic induced cholinergic dysfunctions in rats. Neurotoxicology. 2011;32(6):760–8.
    • (2011) Neurotoxicology , vol.32 , Issue.6 , pp. 760-768
    • Yadav, R.S.1
  • 90
    • 0028238930 scopus 로고
    • Effects on operant learning and brain acetylcholine esterase activity in rats following chronic inorganic arsenic intake
    • PID: 8043317, COI: 1:CAS:528:DyaK2cXlt1OgsL4%3D
    • Nagaraja TN, Desiraju T. Effects on operant learning and brain acetylcholine esterase activity in rats following chronic inorganic arsenic intake. Hum Exp Toxicol. 1994;13(5):353–6.
    • (1994) Hum Exp Toxicol , vol.13 , Issue.5 , pp. 353-356
    • Nagaraja, T.N.1    Desiraju, T.2
  • 91
    • 22044434801 scopus 로고    scopus 로고
    • Serum acetyl cholinesterase as a biomarker of arsenic induced neurotoxicity in sprague-dawley rats
    • PID: 16705804, COI: 1:CAS:528:DC%2BD2MXntFGhsL8%3D
    • Patlolla AK, Tchounwou PB. Serum acetyl cholinesterase as a biomarker of arsenic induced neurotoxicity in sprague-dawley rats. Int J Environ Res Public Health. 2005;2(1):80–3.
    • (2005) Int J Environ Res Public Health , vol.2 , Issue.1 , pp. 80-83
    • Patlolla, A.K.1    Tchounwou, P.B.2
  • 92
    • 55849111494 scopus 로고    scopus 로고
    • Cholinergic system during the progression of Alzheimer's disease: therapeutic implications
    • PID: 18986241, COI: 1:CAS:528:DC%2BD1cXhtlentLvP
    • Mufson EJ et al. Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert Rev Neurother. 2008;8(11):1703–18.
    • (2008) Expert Rev Neurother , vol.8 , Issue.11 , pp. 1703-1718
    • Mufson, E.J.1
  • 93
    • 78651409440 scopus 로고    scopus 로고
    • The arsenic exposure hypothesis for Alzheimer disease
    • Gong G, O'Bryant SE. The arsenic exposure hypothesis for Alzheimer disease. Alzheimer Dis Assoc Disord. 2010. doi:10.1097/WAD.0b013e3181d71bc7.
    • (2010) Alzheimer Dis Assoc Disord
    • Gong, G.1    O'Bryant, S.E.2
  • 94
    • 79955784687 scopus 로고    scopus 로고
    • Arsenic affects expression and processing of amyloid precursor protein (APP) in primary neuronal cells overexpressing the Swedish mutation of human APP
    • PID: 21440049, COI: 1:CAS:528:DC%2BC3MXmtFGmu7s%3D
    • Zarazua S et al. Arsenic affects expression and processing of amyloid precursor protein (APP) in primary neuronal cells overexpressing the Swedish mutation of human APP. Int J Dev Neurosci. 2011;29(4):389–96.
    • (2011) Int J Dev Neurosci , vol.29 , Issue.4 , pp. 389-396
    • Zarazua, S.1
  • 95
    • 0037168486 scopus 로고    scopus 로고
    • The environmental toxin arsenite induces tau hyperphosphorylation
    • PID: 12484777, COI: 1:CAS:528:DC%2BD38XovV2lsL0%3D
    • Giasson BI et al. The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 2002;41(51):15376–87.
    • (2002) Biochemistry , vol.41 , Issue.51 , pp. 15376-15387
    • Giasson, B.I.1
  • 96
    • 80053627394 scopus 로고    scopus 로고
    • Zinc stimulates tau S214 phosphorylation by the activation of Raf/mitogen-activated protein kinase-kinase/extracellular signal-regulated kinase pathway
    • PID: 21934536, COI: 1:CAS:528:DC%2BC3MXht1Oitb3L
    • Kim I et al. Zinc stimulates tau S214 phosphorylation by the activation of Raf/mitogen-activated protein kinase-kinase/extracellular signal-regulated kinase pathway. Neuroreport. 2011;22(16):839–44.
    • (2011) Neuroreport , vol.22 , Issue.16 , pp. 839-844
    • Kim, I.1
  • 97
    • 84655166511 scopus 로고    scopus 로고
    • GSTO1*E155del polymorphism associated with increased risk for late-onset Alzheimer's disease: association hypothesis for an uncommon genetic variant
    • PID: 22100662, COI: 1:CAS:528:DC%2BC38XhtlOlsw%3D%3D
    • Piacentini S et al. GSTO1*E155del polymorphism associated with increased risk for late-onset Alzheimer's disease: association hypothesis for an uncommon genetic variant. Neurosci Lett. 2012;506(2):203–7.
    • (2012) Neurosci Lett , vol.506 , Issue.2 , pp. 203-207
    • Piacentini, S.1
  • 98
    • 30144438819 scopus 로고    scopus 로고
    • Characterization of the omega class of glutathione transferases
    • PID: 16399380, COI: 1:CAS:528:DC%2BD28XoslCju70%3D
    • Whitbread AK et al. Characterization of the omega class of glutathione transferases. Methods Enzymol. 2005;401:78–99.
    • (2005) Methods Enzymol , vol.401 , pp. 78-99
    • Whitbread, A.K.1
  • 99
    • 59149104032 scopus 로고    scopus 로고
    • Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for glutathione synthetase
    • PID: 18779381
    • Ortiz JG et al. Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for glutathione synthetase. Toxicol Sci. 2009;107(2):416–26.
    • (2009) Toxicol Sci , vol.107 , Issue.2 , pp. 416-426
    • Ortiz, J.G.1
  • 100
    • 79954642381 scopus 로고    scopus 로고
    • Advances in metal-induced oxidative stress and human disease
    • PID: 21414382, COI: 1:CAS:528:DC%2BC3MXltFemsrs%3D
    • Jomova K, Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology. 2011;283(2–3):65–87.
    • (2011) Toxicology , vol.283 , Issue.2-3 , pp. 65-87
    • Jomova, K.1    Valko, M.2
  • 101
    • 80051984937 scopus 로고    scopus 로고
    • Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression
    • PID: 21593570, COI: 1:CAS:528:DC%2BC3MXhtFWltbbF
    • Govindarajan N et al. Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression. J Alzheimers Dis. 2011;26(1):187–97.
    • (2011) J Alzheimers Dis , vol.26 , Issue.1 , pp. 187-197
    • Govindarajan, N.1
  • 102
    • 84878790193 scopus 로고    scopus 로고
    • Protective effect of taurine on the decreased biogenic amine neurotransmitter levels in the brain of mice exposed to arsenic
    • PID: 23392890, COI: 1:CAS:528:DC%2BC3sXhvVSnu7jJ
    • Liu X, Piao F, Li Y. Protective effect of taurine on the decreased biogenic amine neurotransmitter levels in the brain of mice exposed to arsenic. Adv Exp Med Biol. 2013;776:277–87.
    • (2013) Adv Exp Med Biol , vol.776 , pp. 277-287
    • Liu, X.1    Piao, F.2    Li, Y.3
  • 103
    • 77956227830 scopus 로고    scopus 로고
    • Neuroprotective effect of curcumin in arsenic-induced neurotoxicity in rats
    • PID: 20466022, COI: 1:CAS:528:DC%2BC3cXhtFWqs7fI
    • Yadav RS et al. Neuroprotective effect of curcumin in arsenic-induced neurotoxicity in rats. Neurotoxicology. 2010;31(5):533–9.
    • (2010) Neurotoxicology , vol.31 , Issue.5 , pp. 533-539
    • Yadav, R.S.1
  • 104
    • 84867230532 scopus 로고    scopus 로고
    • Arsenic-induced inhibition of hippocampal neurogenesis and its reversibility
    • PID: 22561869, COI: 1:CAS:528:DC%2BC38XhsFSrtrrJ, First study to demonstrate that adult expsoure to arsenic impairs neurogenesis and that removal of arsenic from drinking water reverses the deficit
    • Liu S et al. Arsenic-induced inhibition of hippocampal neurogenesis and its reversibility. Neurotoxicology. 2012;33(5):1033–9. First study to demonstrate that adult expsoure to arsenic impairs neurogenesis and that removal of arsenic from drinking water reverses the deficit.
    • (2012) Neurotoxicology , vol.33 , Issue.5 , pp. 1033-1039
    • Liu, S.1
  • 105
    • 84865773184 scopus 로고    scopus 로고
    • Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the beta-catenin signaling pathway
    • PID: 22641621, COI: 1:CAS:528:DC%2BC38Xht1ynsL%2FI
    • Hong GM, Bain LJ. Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the beta-catenin signaling pathway. Toxicol Sci. 2012;129(1):146–56.
    • (2012) Toxicol Sci , vol.129 , Issue.1 , pp. 146-156
    • Hong, G.M.1    Bain, L.J.2
  • 106
    • 84884583255 scopus 로고    scopus 로고
    • Preliminary morphological and immunohistochemical changes in rat hippocampus following postnatal exposure to sodium arsenite
    • PID: 24082510
    • Kaler S et al. Preliminary morphological and immunohistochemical changes in rat hippocampus following postnatal exposure to sodium arsenite. Toxicol Int. 2013;20(2):160–9.
    • (2013) Toxicol Int , vol.20 , Issue.2 , pp. 160-169
    • Kaler, S.1
  • 107
    • 58649098159 scopus 로고    scopus 로고
    • Developmental mechanisms of arsenite toxicity in zebrafish (Danio rerio) embryos
    • PID: 19110324, COI: 1:CAS:528:DC%2BD1MXhtlSgt78%3D
    • Li D et al. Developmental mechanisms of arsenite toxicity in zebrafish (Danio rerio) embryos. Aquat Toxicol. 2009;91(3):229–37.
    • (2009) Aquat Toxicol , vol.91 , Issue.3 , pp. 229-237
    • Li, D.1
  • 108
    • 84875218670 scopus 로고    scopus 로고
    • Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis
    • PID: 23303060, COI: 1:CAS:528:DC%2BC3sXktV2qsbs%3D
    • Anacker C et al. Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis. Neuropsychopharmacology. 2013;38(5):872–83.
    • (2013) Neuropsychopharmacology , vol.38 , Issue.5 , pp. 872-883
    • Anacker, C.1
  • 109
    • 79959586058 scopus 로고    scopus 로고
    • Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor
    • PID: 21483429, COI: 1:CAS:528:DC%2BC3MXnvFOltL0%3D
    • Anacker C et al. Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor. Mol Psychiatry. 2011;16(7):738–50.
    • (2011) Mol Psychiatry , vol.16 , Issue.7 , pp. 738-750
    • Anacker, C.1
  • 110
    • 19444383615 scopus 로고    scopus 로고
    • Mechanistic aspects of the interaction between selenium and arsenic
    • PID: 15917080, COI: 1:CAS:528:DC%2BD2MXks1SlsLg%3D
    • Zeng H, Uthus EO, Combs Jr GF. Mechanistic aspects of the interaction between selenium and arsenic. J Inorg Biochem. 2005;99(6):1269–74.
    • (2005) J Inorg Biochem , vol.99 , Issue.6 , pp. 1269-1274
    • Zeng, H.1    Uthus, E.O.2    Combs, G.F.3
  • 111
    • 84880879291 scopus 로고    scopus 로고
    • A cross-sectional study of the impact of blood selenium on blood and urinary arsenic concentrations in Bangladesh
    • PID: 23816141, COI: 1:CAS:528:DC%2BC3sXht1ygu7fK
    • George CM et al. A cross-sectional study of the impact of blood selenium on blood and urinary arsenic concentrations in Bangladesh. Environ Health. 2013;12:52.
    • (2013) Environ Health , vol.12 , pp. 52
    • George, C.M.1
  • 112
    • 84873412024 scopus 로고    scopus 로고
    • Effect of subchronic exposure to arsenic on levels of essential trace elements in mice brain and its gender difference
    • PID: 23225067, COI: 1:CAS:528:DC%2BC3sXhs1antrg%3D
    • Wang X et al. Effect of subchronic exposure to arsenic on levels of essential trace elements in mice brain and its gender difference. Biometals. 2013;26(1):123–31.
    • (2013) Biometals , vol.26 , Issue.1 , pp. 123-131
    • Wang, X.1
  • 113
    • 33748058123 scopus 로고    scopus 로고
    • Arsenic-induced changes in optic tectal histoarchitecture and acetylcholinesterase-acetylcholine profile in Channa punctatus: amelioration by selenium
    • PID: 16916622
    • Roy S, Chattoraj A, Bhattacharya S. Arsenic-induced changes in optic tectal histoarchitecture and acetylcholinesterase-acetylcholine profile in Channa punctatus: amelioration by selenium. Comp Biochem Physiol C Toxicol Pharmacol. 2006;144(1):16–24.
    • (2006) Comp Biochem Physiol C Toxicol Pharmacol , vol.144 , Issue.1 , pp. 16-24
    • Roy, S.1    Chattoraj, A.2    Bhattacharya, S.3
  • 114
    • 84882754947 scopus 로고    scopus 로고
    • Effectiveness of zinc in modulating perinatal effects of arsenic on the teratological effects in mice offspring
    • PID: 23959010
    • Ahmad M et al. Effectiveness of zinc in modulating perinatal effects of arsenic on the teratological effects in mice offspring. Biol Res. 2013;46(2):131–8.
    • (2013) Biol Res , vol.46 , Issue.2 , pp. 131-138
    • Ahmad, M.1
  • 115
    • 18444369034 scopus 로고    scopus 로고
    • Zinc protects against arsenic-induced apoptosis in a neuronal cell line, measured by DEVD-caspase activity
    • PID: 15689113, COI: 1:CAS:528:DC%2BD2MXht1Wkt74%3D
    • Milton AG, Zalewski PD, Ratnaike RN. Zinc protects against arsenic-induced apoptosis in a neuronal cell line, measured by DEVD-caspase activity. Biometals. 2004;17(6):707–13.
    • (2004) Biometals , vol.17 , Issue.6 , pp. 707-713
    • Milton, A.G.1    Zalewski, P.D.2    Ratnaike, R.N.3
  • 116
    • 78649564732 scopus 로고    scopus 로고
    • Chelation in metal intoxication
    • PID: 20717537, COI: 1:CAS:528:DC%2BC3cXos12lsbk%3D
    • Flora SJ, Pachauri V. Chelation in metal intoxication. Int J Environ Res Public Health. 2010;7(7):2745–88.
    • (2010) Int J Environ Res Public Health , vol.7 , Issue.7 , pp. 2745-2788
    • Flora, S.J.1    Pachauri, V.2
  • 117
    • 84877356350 scopus 로고    scopus 로고
    • Monoisoamyl 2,3-dimercaptosuccinic acid attenuates arsenic induced toxicity: behavioral and neurochemical approach
    • PID: 23644418, COI: 1:CAS:528:DC%2BC3sXnsFSmtbs%3D
    • Ram Kumar M, Flora SJ, Reddy GR. Monoisoamyl 2,3-dimercaptosuccinic acid attenuates arsenic induced toxicity: behavioral and neurochemical approach. Environ Toxicol Pharmacol. 2013;36(1):231–42.
    • (2013) Environ Toxicol Pharmacol , vol.36 , Issue.1 , pp. 231-242
    • Ram Kumar, M.1    Flora, S.J.2    Reddy, G.R.3
  • 118
    • 84885618061 scopus 로고    scopus 로고
    • Prevention of arsenic-mediated reproductive toxicity in adult female rats by high protein diet
    • PID: 23859609, COI: 1:CAS:528:DC%2BC3sXhs1WnsLnE
    • Mondal S et al. Prevention of arsenic-mediated reproductive toxicity in adult female rats by high protein diet. Pharm Biol. 2013;51(11):1363–71.
    • (2013) Pharm Biol , vol.51 , Issue.11 , pp. 1363-1371
    • Mondal, S.1
  • 119
    • 84870523016 scopus 로고    scopus 로고
    • Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in Bangladesh
    • PID: 23060367, COI: 1:CAS:528:DC%2BC3sXhsValtr0%3D
    • Seow WJ et al. Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in Bangladesh. Environ Health Perspect. 2012;120(12):1733–8.
    • (2012) Environ Health Perspect , vol.120 , Issue.12 , pp. 1733-1738
    • Seow, W.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.