Investigating arsenic susceptibility from a genetic perspective in drosophila reveals a key role for glutathione synthetase

Toxicological Sciences

Volumn 107, Issue 2, 2009, Pages 416-426

  Muñiz Ortiz, Jorge G ^a   Opoka, Robert ^a   Kane, Daniel ^a   Cartwright, Iain L ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Arsenite toxicity; Drosophila; Genetic variability; Glutathione synthetase; RNA interference

Indexed keywords

ARSENIC; GLUTATHIONE SYNTHASE;

ARTICLE; BIOSYNTHESIS; CHEMOSENSITIVITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; GENE MAPPING; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; MICROSATELLITE MARKER; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; RNA INTERFERENCE; TOXICITY TESTING; TOXICOGENETICS; WILD TYPE; X CHROMOSOME;

ALLELES; ANIMALS; ANTIOXIDANTS; ARSENIC; ARSENITES; CELL SURVIVAL; CELLS, CULTURED; CHROMOSOME DELETION; CHROMOSOME MAPPING; DROSOPHILA MELANOGASTER; FEMALE; GLUTATHIONE; GLUTATHIONE SYNTHASE; MALE; MICROSATELLITE REPEATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; X CHROMOSOME;

MAMMALIA;

EID: 59149104032     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn192     Document Type: Article

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