Free paclitaxel loaded PEGylated-paclitaxel nanoparticles: Preparation and comparison with other paclitaxel systems in vitro and in vivo

International Journal of Pharmaceutics

Volumn 471, Issue 1-2, 2014, Pages 525-535

  Lu, Jingkai ^a   Chuan, Xingxing ^a   Zhang, Hua ^a   Dai, Wenbing ^a   Wang, Xinglin ^b   Wang, Xueqing ^a   Zhang, Qiang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Antitumor effect; Nanoparticles; Paclitaxel; PEG PLA; PEGylated paclitaxel; Taxol

Indexed keywords

COUMARIN; NANOPARTICLE; PACLITAXEL; ANTINEOPLASTIC AGENT; DRUG CARRIER; MACROGOL DERIVATIVE; MICELLE; MONOMETHOXYPOLYETHYLENEGLYCOL-POLYLACTIDE BLOCK COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG RELEASE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; ANIMAL; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; DRUG FORMULATION; DRUG SCREENING; DRUG STABILITY; ERYTHROCYTE; FEMALE; HEMOLYSIS; HUMAN; NUDE MOUSE; PARTICLE SIZE; PROCEDURES; SOLUBILITY; SURFACE PROPERTY; TOXICITY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; DRUG STABILITY; ERYTHROCYTES; FEMALE; HEMOLYSIS; HUMANS; MCF-7 CELLS; MICE; MICE, NUDE; MICELLES; NANOPARTICLES; PACLITAXEL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; SOLUBILITY; SURFACE PROPERTIES; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903391233     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.032     Document Type: Article

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