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Volumn 30, Issue 7-8, 2014, Pages 897-902

Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans

Author keywords

Fatty acid desaturase; Phospholipids; Single nucleotide polymorphism; Type 2 diabetes

Indexed keywords

ACYL COENZYME A DESATURASE; FATTY ACID; DELTA-5 FATTY ACID DESATURASE; FADS2 PROTEIN, HUMAN; FADS3 PROTEIN, HUMAN; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHOLIPID;

EID: 84903378556     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2014.01.006     Document Type: Article
Times cited : (17)

References (32)
  • 1
    • 77952389187 scopus 로고    scopus 로고
    • Increased plasma n-3 polyunsaturated fatty acid is associated with improved insulin sensitivity in type 2 diabetes in China
    • Huang T., Wahlqvist M.L., Xu T.C., Xu A., Zhang A.Z., et al. Increased plasma n-3 polyunsaturated fatty acid is associated with improved insulin sensitivity in type 2 diabetes in China. Mol Nutr Food Res 2010, 54:S112-S119.
    • (2010) Mol Nutr Food Res , vol.54
    • Huang, T.1    Wahlqvist, M.L.2    Xu, T.C.3    Xu, A.4    Zhang, A.Z.5
  • 2
    • 78349257835 scopus 로고    scopus 로고
    • Plasma phospholipids n-3 polyunsaturated fatty acid is associated with metabolic syndrome
    • Huang T., Bhulaidok S., Cai Z.Z., Xu T.C., Xu F., Wahlqvist M.L., et al. Plasma phospholipids n-3 polyunsaturated fatty acid is associated with metabolic syndrome. Mol Nutr Food Res 2010, 54:1628-1635.
    • (2010) Mol Nutr Food Res , vol.54 , pp. 1628-1635
    • Huang, T.1    Bhulaidok, S.2    Cai, Z.Z.3    Xu, T.C.4    Xu, F.5    Wahlqvist, M.L.6
  • 3
    • 33747049581 scopus 로고    scopus 로고
    • Plasma phospholipid trans fatty acids, fatal ischemic heart disease, and sudden cardiac death in older adults: the cardiovascular health study
    • Lemaitre R.N., King I.B., Mozaffarian D., Sotoodehnia N., Rea T.D., Kuller L.H., et al. Plasma phospholipid trans fatty acids, fatal ischemic heart disease, and sudden cardiac death in older adults: the cardiovascular health study. Circulation 2006, 114:209-215.
    • (2006) Circulation , vol.114 , pp. 209-215
    • Lemaitre, R.N.1    King, I.B.2    Mozaffarian, D.3    Sotoodehnia, N.4    Rea, T.D.5    Kuller, L.H.6
  • 4
    • 34147132675 scopus 로고    scopus 로고
    • Erythrocyte fatty acids and breast cancer risk: a case-control study in Shanghai, China
    • Shannon J., King I.B., Moshofsky R., Lampe J.W., Gao D.L., Ray R.M., et al. Erythrocyte fatty acids and breast cancer risk: a case-control study in Shanghai, China. Am J Clin Nutr 2007, 85:1090-1097.
    • (2007) Am J Clin Nutr , vol.85 , pp. 1090-1097
    • Shannon, J.1    King, I.B.2    Moshofsky, R.3    Lampe, J.W.4    Gao, D.L.5    Ray, R.M.6
  • 5
    • 0037358858 scopus 로고    scopus 로고
    • Omega-3 fatty acids and non-communicable diseases
    • Li D. Omega-3 fatty acids and non-communicable diseases. Chin Med J (Engl) 2003, 116:453-458.
    • (2003) Chin Med J (Engl) , vol.116 , pp. 453-458
    • Li, D.1
  • 6
    • 0037088677 scopus 로고    scopus 로고
    • The biochemistry of n-3 polyunsaturated fatty acids
    • Jump D.B. The biochemistry of n-3 polyunsaturated fatty acids. World J Biol Chem 2002, 277:8755-8758.
    • (2002) World J Biol Chem , vol.277 , pp. 8755-8758
    • Jump, D.B.1
  • 7
    • 0142196218 scopus 로고    scopus 로고
    • Conversion of alpha-linolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women
    • Burdge G.C., Wootton S.A. Conversion of alpha-linolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women. Prostaglandins Leukot Essent Fatty Acids 2003, 69:283-290.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.69 , pp. 283-290
    • Burdge, G.C.1    Wootton, S.A.2
  • 8
    • 42949100257 scopus 로고    scopus 로고
    • Familial aggregation of red blood cell membrane fatty acid composition: the Kibbutzim Family Study
    • Lemaitre R.N., Siscovick D.S., Berry E.M., Kark J.D., Friedlander Y. Familial aggregation of red blood cell membrane fatty acid composition: the Kibbutzim Family Study. Metab Clin Exp 2008, 57:662-668.
    • (2008) Metab Clin Exp , vol.57 , pp. 662-668
    • Lemaitre, R.N.1    Siscovick, D.S.2    Berry, E.M.3    Kark, J.D.4    Friedlander, Y.5
  • 9
    • 33744736614 scopus 로고    scopus 로고
    • Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
    • Schaeffer L., Gohlke H., Muller M., Heid I.M., Palmer L.J., Kompauer I., et al. Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet 2006, 15:1745-1756.
    • (2006) Hum Mol Genet , vol.15 , pp. 1745-1756
    • Schaeffer, L.1    Gohlke, H.2    Muller, M.3    Heid, I.M.4    Palmer, L.J.5    Kompauer, I.6
  • 10
    • 55949102407 scopus 로고    scopus 로고
    • Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation
    • Xie L., Innis S.M. Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation. J Nutr 2008, 138:2222-2228.
    • (2008) J Nutr , vol.138 , pp. 2222-2228
    • Xie, L.1    Innis, S.M.2
  • 11
    • 77955425717 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios
    • Bokor S., Dumont J., Spinneker A., Gonzalez-Gross M., Nova E., Widhalm K., et al. Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios. J Lipid Res 2010, 51:2325-2333.
    • (2010) J Lipid Res , vol.51 , pp. 2325-2333
    • Bokor, S.1    Dumont, J.2    Spinneker, A.3    Gonzalez-Gross, M.4    Nova, E.5    Widhalm, K.6
  • 12
    • 78649991062 scopus 로고    scopus 로고
    • Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study
    • Zietemann V., Kroger J., Enzenbach C., Jansen E., Fritsche A., Weikert C., et al. Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study. Br J Nutr 2010, 104:1748-1759.
    • (2010) Br J Nutr , vol.104 , pp. 1748-1759
    • Zietemann, V.1    Kroger, J.2    Enzenbach, C.3    Jansen, E.4    Fritsche, A.5    Weikert, C.6
  • 13
    • 59249096217 scopus 로고    scopus 로고
    • Genome-Wide Association Study of plasma polyunsaturated fatty acids in the In CHIANTI Study
    • Tanaka T., Shen J., Abecasis G.R., Kisialiou A., Ordovas J.M., Guralnik J.M., et al. Genome-Wide Association Study of plasma polyunsaturated fatty acids in the In CHIANTI Study. PLoS Genet 2009, 5:E1000338.
    • (2009) PLoS Genet , vol.5
    • Tanaka, T.1    Shen, J.2    Abecasis, G.R.3    Kisialiou, A.4    Ordovas, J.M.5    Guralnik, J.M.6
  • 14
    • 79960947310 scopus 로고    scopus 로고
    • Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of Genome-Wide Association Studies from the CHARGE Consortium
    • Lemaitre R.N., Tanaka T., Tang W.H., Manichaikul A., Foy M., Kabagambe E.K., et al. Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of Genome-Wide Association Studies from the CHARGE Consortium. PLoS Genet 2011, 7.
    • (2011) PLoS Genet , pp. 7
    • Lemaitre, R.N.1    Tanaka, T.2    Tang, W.H.3    Manichaikul, A.4    Foy, M.5    Kabagambe, E.K.6
  • 15
    • 70349417898 scopus 로고    scopus 로고
    • Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance
    • Warensjo E., Rosell M., Hellenius M.L., Vessby B., De Faire U., Riserus U. Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance. Lipids Health Dis 2009, 8.
    • (2009) Lipids Health Dis , vol.8
    • Warensjo, E.1    Rosell, M.2    Hellenius, M.L.3    Vessby, B.4    De Faire, U.5    Riserus, U.6
  • 16
    • 78651287448 scopus 로고    scopus 로고
    • Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
    • Kroger J., Zietemann V., Enzenbach C., Weikert C., Jansen E.H.J.M., Doring F., et al. Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Am J Clin Nutr 2011, 93:127-142.
    • (2011) Am J Clin Nutr , vol.93 , pp. 127-142
    • Kroger, J.1    Zietemann, V.2    Enzenbach, C.3    Weikert, C.4    Jansen, E.H.J.M.5    Doring, F.6
  • 17
    • 84855833330 scopus 로고    scopus 로고
    • Recent insights into the relation of delta 5 desaturase and delta 6 desaturase activity to the development of type 2 diabetes
    • Kroger J., Schulze M.B. Recent insights into the relation of delta 5 desaturase and delta 6 desaturase activity to the development of type 2 diabetes. Curr Opin Lipidol 2012, 23:4-10.
    • (2012) Curr Opin Lipidol , vol.23 , pp. 4-10
    • Kroger, J.1    Schulze, M.B.2
  • 18
    • 34250815246 scopus 로고
    • Qualitative and quantitative determination of the fatty acids by gas-liquid chromatography
    • James A.T. Qualitative and quantitative determination of the fatty acids by gas-liquid chromatography. Methods Biochem Anal 1960, 8:1-59.
    • (1960) Methods Biochem Anal , vol.8 , pp. 1-59
    • James, A.T.1
  • 19
    • 42449113349 scopus 로고    scopus 로고
    • PPARGC1 A variation associated with DNA damage, diabetes, and cardiovascular diseases-the Boston Puerto Rican Health Study
    • Lai C.Q., Tucker K.L., Parnell L.D., Adiconis M., Garcia-Bailo B., Griffith J., et al. PPARGC1 A variation associated with DNA damage, diabetes, and cardiovascular diseases-the Boston Puerto Rican Health Study. Diabetes 2008, 57:809-816.
    • (2008) Diabetes , vol.57 , pp. 809-816
    • Lai, C.Q.1    Tucker, K.L.2    Parnell, L.D.3    Adiconis, M.4    Garcia-Bailo, B.5    Griffith, J.6
  • 20
    • 84856752552 scopus 로고    scopus 로고
    • Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome
    • Sergeant S., Hugenschmidt C.E., Rudock M.E., Ziegler J.T., Ivester P., Ainsworth H.C., et al. Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome. Br J Nutr 2012, 107:547-555.
    • (2012) Br J Nutr , vol.107 , pp. 547-555
    • Sergeant, S.1    Hugenschmidt, C.E.2    Rudock, M.E.3    Ziegler, J.T.4    Ivester, P.5    Ainsworth, H.C.6
  • 21
    • 79956263594 scopus 로고    scopus 로고
    • Polymorphisms in FADS1 and FADS2 alter desaturase activity in young caucasian and Asian adults
    • Merino D.M., Johnston H., Clarke S., Roke K., Nielsen D., Badawi A., et al. Polymorphisms in FADS1 and FADS2 alter desaturase activity in young caucasian and Asian adults. Mol Genet Metab 2011, 103:171-178.
    • (2011) Mol Genet Metab , vol.103 , pp. 171-178
    • Merino, D.M.1    Johnston, H.2    Clarke, S.3    Roke, K.4    Nielsen, D.5    Badawi, A.6
  • 22
    • 79956194616 scopus 로고    scopus 로고
    • The impact of FADS genetic variants on omega 6 polyunsaturated fatty acid metabolism in African Americans
    • Mathias R.A., Sergeant S., Ruczinski I., Torgerson D.G., Hugenschmidt C.E., Kubala M., et al. The impact of FADS genetic variants on omega 6 polyunsaturated fatty acid metabolism in African Americans. BMC Genet 2011, 12.
    • (2011) BMC Genet , pp. 12
    • Mathias, R.A.1    Sergeant, S.2    Ruczinski, I.3    Torgerson, D.G.4    Hugenschmidt, C.E.5    Kubala, M.6
  • 23
    • 33846868388 scopus 로고    scopus 로고
    • Alpha-linolenic acid, delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction
    • Baylin A., Ruiz-Narvaez E., Kraft P., Campos H. Alpha-linolenic acid, delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction. Am J Clin Nutr 2007, 85:554-560.
    • (2007) Am J Clin Nutr , vol.85 , pp. 554-560
    • Baylin, A.1    Ruiz-Narvaez, E.2    Kraft, P.3    Campos, H.4
  • 24
    • 53849097341 scopus 로고    scopus 로고
    • FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease
    • Martinelli N., Girelli D., Malerba G., Guarini P., Illig T., Trabetti E., et al. FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. Am J Clin Nutr 2008, 88:941-949.
    • (2008) Am J Clin Nutr , vol.88 , pp. 941-949
    • Martinelli, N.1    Girelli, D.2    Malerba, G.3    Guarini, P.4    Illig, T.5    Trabetti, E.6
  • 25
    • 57349126752 scopus 로고    scopus 로고
    • Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes
    • Rzehak P., Heinrich J., Klopp N., Schaeffer L., Hoff S., Wolfram G., et al. Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes. Br J Nutr 2009, 101:20-26.
    • (2009) Br J Nutr , vol.101 , pp. 20-26
    • Rzehak, P.1    Heinrich, J.2    Klopp, N.3    Schaeffer, L.4    Hoff, S.5    Wolfram, G.6
  • 26
    • 46149088018 scopus 로고    scopus 로고
    • SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease
    • Malerba G., Schaeffer L., Xumerle L., Klopp N., Trabetti E., Biscuola M., et al. SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease. Lipids 2008, 43:289-299.
    • (2008) Lipids , vol.43 , pp. 289-299
    • Malerba, G.1    Schaeffer, L.2    Xumerle, L.3    Klopp, N.4    Trabetti, E.5    Biscuola, M.6
  • 27
    • 77953312331 scopus 로고    scopus 로고
    • Comparison of cardiovascular risk profiles among ethnic groups using population health surveys between 1996 and 2007
    • Chiu M., Austin P.C., Manuel D.G., Tu J.V. Comparison of cardiovascular risk profiles among ethnic groups using population health surveys between 1996 and 2007. CMAJ 2010, 182:E301-E310.
    • (2010) CMAJ , vol.182
    • Chiu, M.1    Austin, P.C.2    Manuel, D.G.3    Tu, J.V.4
  • 28
    • 84861994726 scopus 로고    scopus 로고
    • Erythrocyte n-3 fatty acids and metabolic syndrome in middle-aged and older Chinese
    • Zhang G., Sun Q., Hu F.B., Ye X., Yu Z., Zong G., et al. Erythrocyte n-3 fatty acids and metabolic syndrome in middle-aged and older Chinese. J Clin Endocrinol Metab 2012, 97:E973-E977.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Zhang, G.1    Sun, Q.2    Hu, F.B.3    Ye, X.4    Yu, Z.5    Zong, G.6
  • 29
    • 0033978888 scopus 로고    scopus 로고
    • Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism
    • Roche H.M., Gibney M.J. Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism. Am J Clin Nutr 2000, 71:232s-237s.
    • (2000) Am J Clin Nutr , vol.71
    • Roche, H.M.1    Gibney, M.J.2
  • 30
    • 53849097341 scopus 로고    scopus 로고
    • FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease
    • Martinelli N., Girelli D., Malerba G., Guarini P., Illig T., Trabetti E., et al. FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. Am J Clin Nutr 2008, 88:941-949.
    • (2008) Am J Clin Nutr , vol.88 , pp. 941-949
    • Martinelli, N.1    Girelli, D.2    Malerba, G.3    Guarini, P.4    Illig, T.5    Trabetti, E.6
  • 31
    • 62649085037 scopus 로고    scopus 로고
    • Elevated delta-6 desaturase (FADS2) expression in the postmortem prefrontal cortex of schizophrenic patients: Relationship with fatty acid composition
    • Liu Y.H., Jandacek R., Rider T., Tso P., McNamara R.K. Elevated delta-6 desaturase (FADS2) expression in the postmortem prefrontal cortex of schizophrenic patients: Relationship with fatty acid composition. Schizophr Res 2009, 109:113-120.
    • (2009) Schizophr Res , vol.109 , pp. 113-120
    • Liu, Y.H.1    Jandacek, R.2    Rider, T.3    Tso, P.4    McNamara, R.K.5
  • 32
    • 79955000165 scopus 로고    scopus 로고
    • Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study
    • Kim O.Y., Lim H.H., Yang L.I., Chae J.S., Lee J.H. Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study. Nutr Metab (Lond) 2011, 8:24.
    • (2011) Nutr Metab (Lond) , vol.8 , pp. 24
    • Kim, O.Y.1    Lim, H.H.2    Yang, L.I.3    Chae, J.S.4    Lee, J.H.5


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