-
1
-
-
79953810341
-
Wnt signaling and orthopedics, an overview
-
Agholme F, Aspenberg P., 2011. Wnt signaling and orthopedics, an overview. Acta Orthop 82: 125-130.
-
(2011)
Acta Orthop
, vol.82
, pp. 125-130
-
-
Agholme, F.1
Aspenberg, P.2
-
2
-
-
0035282968
-
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
-
Balemans W, Ebeling M, Patel N, et al. 2001. Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum Mol Genet 10: 537-543.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 537-543
-
-
Balemans, W.1
Ebeling, M.2
Patel, N.3
-
3
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
Li X, Ominsky MS, Niu QT, et al. 2008. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 23: 860-869.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.T.3
-
4
-
-
77952992328
-
Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice
-
Kramer I, Loots GG, Studer A, et al. 2010. Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice. J Bone Miner Res 25: 178-189.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 178-189
-
-
Kramer, I.1
Loots, G.G.2
Studer, A.3
-
5
-
-
65549152230
-
Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
-
Li X, Ominsky MS, Warmington KS, et al. 2009. Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res 24: 578-588.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 578-588
-
-
Li, X.1
Ominsky, M.S.2
Warmington, K.S.3
-
6
-
-
84868290353
-
Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases
-
Ke HZ, Richards WG, Li X, et al. 2012. Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. Endocr Rev 33: 747-783.
-
(2012)
Endocr Rev
, vol.33
, pp. 747-783
-
-
Ke, H.Z.1
Richards, W.G.2
Li, X.3
-
7
-
-
84903283898
-
Site- and compartment-specific effects of microgravity on the skeleton in mice flown on the STS-135 shuttle mission
-
(Suppl 1). Available at. Accessed February 01, 2013
-
Ellman R, Ferguson VL, Livingston EW, et al. 2012. Site- and compartment-specific effects of microgravity on the skeleton in mice flown on the STS-135 shuttle mission. J Bone Miner Res 27 (Suppl 1). Available at http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid= 5aca4f21-dae4-4a92-add4-196287ecbe79. Accessed February 01, 2013.
-
(2012)
J Bone Miner Res
, vol.27
-
-
Ellman, R.1
Ferguson, V.L.2
Livingston, E.W.3
-
8
-
-
78650958526
-
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
-
Padhi D, Jang G, Stouch B, et al. 2011. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 26: 19-26.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 19-26
-
-
Padhi, D.1
Jang, G.2
Stouch, B.3
-
9
-
-
84865509876
-
Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats
-
McDonald MM, Morse A, Mikulec K, et al. 2012. Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats. J Orthop Res 30: 1541-1548.
-
(2012)
J Orthop Res
, vol.30
, pp. 1541-1548
-
-
McDonald, M.M.1
Morse, A.2
Mikulec, K.3
-
10
-
-
84870243397
-
Effects of sclerostin antibody on healing of a non-critical size femoral bone defect
-
Jawad MU, Fritton KE, Ma T, et al. 2013. Effects of sclerostin antibody on healing of a non-critical size femoral bone defect. J Orthop Res 31: 155-163.
-
(2013)
J Orthop Res
, vol.31
, pp. 155-163
-
-
Jawad, M.U.1
Fritton, K.E.2
Ma, T.3
-
11
-
-
84880166280
-
Systemic administration of sclerostin antibody enhances bone repair in a critical-sized femoral defect in a rat model
-
Virk MS, Alaee F, Tang H, et al. 2013. Systemic administration of sclerostin antibody enhances bone repair in a critical-sized femoral defect in a rat model. J Bone Joint Surg Am 95: 694-701.
-
(2013)
J Bone Joint Surg Am
, vol.95
, pp. 694-701
-
-
Virk, M.S.1
Alaee, F.2
Tang, H.3
-
12
-
-
84873964702
-
Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus
-
Hamann C, Rauner M, Hohna Y, et al. 2013. Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus. J Bone Miner Res 28: 627-638.
-
(2013)
J Bone Miner Res
, vol.28
, pp. 627-638
-
-
Hamann, C.1
Rauner, M.2
Hohna, Y.3
-
13
-
-
0033073616
-
Comparison of healing process in open osteotomy model and closed fracture model
-
Park SH, O'Connor K, Sung R, et al. 1999. Comparison of healing process in open osteotomy model and closed fracture model. J Orthop Trauma 13: 114-120.
-
(1999)
J Orthop Trauma
, vol.13
, pp. 114-120
-
-
Park, S.H.1
O'Connor, K.2
Sung, R.3
-
14
-
-
0035204447
-
Rates and odds ratios for complications in closed and open tibial fractures treated with unreamed, small diameter tibial nails: A multicenter analysis of 467 cases
-
Gaebler C, Berger U, Schandelmaier P, et al. 2001. Rates and odds ratios for complications in closed and open tibial fractures treated with unreamed, small diameter tibial nails: a multicenter analysis of 467 cases. J Orthop Trauma 15: 415-423.
-
(2001)
J Orthop Trauma
, vol.15
, pp. 415-423
-
-
Gaebler, C.1
Berger, U.2
Schandelmaier, P.3
-
15
-
-
34548537788
-
Changes of microstructure and mineralized tissue in the middle and late phase of osteoporotic fracture healing in rats
-
Hao YJ, Zhang G, Wang YS, et al. 2007. Changes of microstructure and mineralized tissue in the middle and late phase of osteoporotic fracture healing in rats. Bone 41: 631-638.
-
(2007)
Bone
, vol.41
, pp. 631-638
-
-
Hao, Y.J.1
Zhang, G.2
Wang, Y.S.3
-
16
-
-
77649192186
-
Intermittent PTH(1-34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures
-
Tagil M, McDonald MM, Morse A, et al. 2010. Intermittent PTH(1-34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures. Bone 46: 852-859.
-
(2010)
Bone
, vol.46
, pp. 852-859
-
-
Tagil, M.1
McDonald, M.M.2
Morse, A.3
-
17
-
-
54349085408
-
Characterization of a rat osteotomy model with impaired healing
-
Kratzel C, Bergmann C, Duda G, et al. 2008. Characterization of a rat osteotomy model with impaired healing. BMC Musculoskelet Disord 9: 135.
-
(2008)
BMC Musculoskelet Disord
, vol.9
, pp. 135
-
-
Kratzel, C.1
Bergmann, C.2
Duda, G.3
-
18
-
-
79955635177
-
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones
-
Ominsky MS, Li C, Li X, et al. 2011. Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones. J Bone Miner Res 26: 1012-1021.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 1012-1021
-
-
Ominsky, M.S.1
Li, C.2
Li, X.3
-
19
-
-
84870520089
-
Extracorporeal shockwave therapy for treatment of delayed tendon-bone insertion healing in a rabbit model: A dose-response study
-
Chow DH, Suen PK, Fu LH, et al. 2012. Extracorporeal shockwave therapy for treatment of delayed tendon-bone insertion healing in a rabbit model: a dose-response study. Am J Sports Med 40: 2862-2871.
-
(2012)
Am J Sports Med
, vol.40
, pp. 2862-2871
-
-
Chow, D.H.1
Suen, P.K.2
Fu, L.H.3
-
20
-
-
84857360107
-
Deletion of estrogen receptor beta accelerates early stage of bone healing in a mouse osteotomy model
-
He YX, Liu Z, Pan XH, et al. 2012. Deletion of estrogen receptor beta accelerates early stage of bone healing in a mouse osteotomy model. Osteoporos Int 23: 377-389.
-
(2012)
Osteoporos Int
, vol.23
, pp. 377-389
-
-
He, Y.X.1
Liu, Z.2
Pan, X.H.3
-
21
-
-
0142182402
-
PQCT bone strength index may serve as a better predictor than bone mineral density for long bone breaking strength
-
Siu WS, Qin L, Leung KS., 2003. pQCT bone strength index may serve as a better predictor than bone mineral density for long bone breaking strength. J Bone Miner Res 21: 316-322.
-
(2003)
J Bone Miner Res
, vol.21
, pp. 316-322
-
-
Siu, W.S.1
Qin, L.2
Leung, K.S.3
-
22
-
-
77951255615
-
Low-magnitude high-frequency vibration treatment augments fracture healing in ovariectomy-induced osteoporotic bone
-
Shi HF, Cheung WH, Qin L, et al. 2010. Low-magnitude high-frequency vibration treatment augments fracture healing in ovariectomy-induced osteoporotic bone. Bone 46: 1299-1305.
-
(2010)
Bone
, vol.46
, pp. 1299-1305
-
-
Shi, H.F.1
Cheung, W.H.2
Qin, L.3
-
23
-
-
20844434360
-
Angiogenesis is required for successful bone induction during distraction osteogenesis
-
Fang TD, Salim A, Xia W, et al. 2005. Angiogenesis is required for successful bone induction during distraction osteogenesis. J Bone Miner Res 20: 1114-1124.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 1114-1124
-
-
Fang, T.D.1
Salim, A.2
Xia, W.3
-
24
-
-
42449132519
-
Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling
-
Jacobsen KA, Al-Aql ZS, Wan C, et al. 2008. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res 23: 596-609.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 596-609
-
-
Jacobsen, K.A.1
Al-Aql, Z.S.2
Wan, C.3
-
25
-
-
34249913494
-
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development
-
Wang Y, Wan C, Deng L, et al. 2007. The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest 117: 1616-1626.
-
(2007)
J Clin Invest
, vol.117
, pp. 1616-1626
-
-
Wang, Y.1
Wan, C.2
Deng, L.3
-
26
-
-
84864088681
-
Osteoblast-specific transcription factor Osterix (Osx) and HIF-1alpha cooperatively regulate gene expression of vascular endothelial growth factor (VEGF)
-
Chen D, Tian W, Li Y, et al. 2012. Osteoblast-specific transcription factor Osterix (Osx) and HIF-1alpha cooperatively regulate gene expression of vascular endothelial growth factor (VEGF). Biochem Biophys Res Commun 424: 176-181.
-
(2012)
Biochem Biophys Res Commun
, vol.424
, pp. 176-181
-
-
Chen, D.1
Tian, W.2
Li, Y.3
-
27
-
-
84862918101
-
Transcriptional regulation of vascular endothelial growth factor (VEGF) by osteoblast-specific transcription factor osterix (Osx) in osteoblasts
-
Tang WJ, Yang F, Li Y, et al. 2012. Transcriptional regulation of vascular endothelial growth factor (VEGF) by osteoblast-specific transcription factor osterix (Osx) in osteoblasts. J Biol Chem 287: 1671-1678.
-
(2012)
J Biol Chem
, vol.287
, pp. 1671-1678
-
-
Tang, W.J.1
Yang, F.2
Li, Y.3
-
29
-
-
0038745735
-
Beta-Catenin regulates vascular endothelial growth factor expression in colon cancer
-
Easwaran V, Lee SH, Inge L, et al. 2003. beta-Catenin regulates vascular endothelial growth factor expression in colon cancer. Cancer Res 63: 3145-3153.
-
(2003)
Cancer Res
, vol.63
, pp. 3145-3153
-
-
Easwaran, V.1
Lee, S.H.2
Inge, L.3
-
30
-
-
75049083784
-
Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones
-
Maes C, Goossens S, Bartunkova S, et al. 2010. Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J 29: 424-441.
-
(2010)
EMBO J
, vol.29
, pp. 424-441
-
-
Maes, C.1
Goossens, S.2
Bartunkova, S.3
-
31
-
-
84878913767
-
HIF-1alpha inhibits Wnt signaling pathway by activating Sost expression in osteoblasts
-
Chen D, Li Y, Zhou Z, et al. 2013. HIF-1alpha inhibits Wnt signaling pathway by activating Sost expression in osteoblasts. PLoS ONE 8: e65940.
-
(2013)
PLoS ONE
, vol.8
-
-
Chen, D.1
Li, Y.2
Zhou, Z.3
-
32
-
-
44349125905
-
Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix
-
Zhang C, Cho K, Huang Y, et al. 2008. Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix. Proc Natl Acad Sci USA 105: 6936-6941.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6936-6941
-
-
Zhang, C.1
Cho, K.2
Huang, Y.3
-
33
-
-
84871660142
-
Synergistic inhibition of Wnt pathway by HIF-1alpha and osteoblast-specific transcription factor osterix (Osx) in osteoblasts
-
Chen D, Li Y, Zhou Z, et al. 2012. Synergistic inhibition of Wnt pathway by HIF-1alpha and osteoblast-specific transcription factor osterix (Osx) in osteoblasts. PLoS ONE 7: e52948.
-
(2012)
PLoS ONE
, vol.7
-
-
Chen, D.1
Li, Y.2
Zhou, Z.3
-
34
-
-
79957859079
-
Angiogenesis in bone regeneration
-
Hankenson KD, Dishowitz M, Gray C, et al. 2011. Angiogenesis in bone regeneration. Injury 42: 556-561.
-
(2011)
Injury
, vol.42
, pp. 556-561
-
-
Hankenson, K.D.1
Dishowitz, M.2
Gray, C.3
-
35
-
-
79957809134
-
The biology of fracture healing
-
Marsell R, Einhorn TA., 2011. The biology of fracture healing. Injury 42: 551-555.
-
(2011)
Injury
, vol.42
, pp. 551-555
-
-
Marsell, R.1
Einhorn, T.A.2
-
36
-
-
33845417683
-
Trends in the management of open fractures. A critical analysis
-
Okike K, Bhattacharyya T., 2006. Trends in the management of open fractures. A critical analysis. J Bone Joint Surg Am 88: 2739-2748.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 2739-2748
-
-
Okike, K.1
Bhattacharyya, T.2
-
37
-
-
84882663410
-
Investigating the synergistic efficacy of BMP-7 and zoledronate on bone allografts using an open rat osteotomy model
-
Mathavan N, Bosemark P, Isaksson H, et al. 2013. Investigating the synergistic efficacy of BMP-7 and zoledronate on bone allografts using an open rat osteotomy model. Bone 56: 440-448.
-
(2013)
Bone
, vol.56
, pp. 440-448
-
-
Mathavan, N.1
Bosemark, P.2
Isaksson, H.3
-
38
-
-
84873897043
-
Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength
-
Bosemark P, Isaksson H, McDonald MM, et al. 2013. Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength. Acta Orthop 84: 106-111.
-
(2013)
Acta Orthop
, vol.84
, pp. 106-111
-
-
Bosemark, P.1
Isaksson, H.2
McDonald, M.M.3
-
39
-
-
58649117944
-
Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration
-
Colnot C., 2009. Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration. J Bone Miner Res 24: 274-282.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 274-282
-
-
Colnot, C.1
-
40
-
-
0029704231
-
Effects of periosteal stripping on healing of segmental fractures in rats
-
Utvag SE, Grundnes O, Reikeraos O., 1996. Effects of periosteal stripping on healing of segmental fractures in rats. J Orthop Trauma 10: 279-284.
-
(1996)
J Orthop Trauma
, vol.10
, pp. 279-284
-
-
Utvag, S.E.1
Grundnes, O.2
Reikeraos, O.3
|