-
1
-
-
84873033171
-
ACE2, angiotensin-(1-7), and Mas: The other side of the coin
-
doi:10.1007/s00424-012-1120-0. PMID:23463883
-
Bader, M. 2013. ACE2, angiotensin-(1-7), and Mas: the other side of the coin. Pflugers Arch. 465(1): 79-85. doi:10.1007/s00424-012-1120-0. PMID:23463883.
-
(2013)
Pflugers Arch
, vol.465
, Issue.1
, pp. 79-85
-
-
Bader, M.1
-
2
-
-
33846221988
-
Angiotensin-(1-7) prevents diabetes-induced cardiovascular dysfunction
-
doi:10.1152/ajpheart.00372.2006. PMID:17213482
-
Benter, I.F., Yousif, M.H., Cojocel, C., Al-Maghrebi, M., and Diz, D.I. 2007. Angiotensin-(1-7) prevents diabetes-induced cardiovascular dysfunction. Am. J. Physiol. Heart Circ. Physiol. 292(1): H666-H672. doi:10.1152/ajpheart.00372.2006. PMID:17213482.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.292
, Issue.1
-
-
Benter, I.F.1
Yousif, M.H.2
Cojocel, C.3
Al-Maghrebi, M.4
Diz, D.I.5
-
3
-
-
77957558776
-
Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice
-
doi:10.2337/db09-0782. PMID:20660625
-
Bindom, S.M., Hans, C.P., Xia, H., Boulares, A.H., and Lazartigues, E. 2010. Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. Diabetes, 59(10): 2540-2548. doi:10.2337/db09-0782. PMID:20660625.
-
(2010)
Diabetes
, vol.59
, Issue.10
, pp. 2540-2548
-
-
Bindom, S.M.1
Hans, C.P.2
Xia, H.3
Boulares, A.H.4
Lazartigues, E.5
-
4
-
-
79958820082
-
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit
-
doi:10.1093/cvr/cvr036. PMID:21285291
-
Bodiga, S., Zhong, J.C., Wang, W., Basu, R., Lo, J., Liu, G.C., et al. 2011. Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit. Cardiovasc. Res. 91(1): 151-161. doi:10.1093/cvr/cvr036. PMID:21285291.
-
(2011)
Cardiovasc. Res
, vol.91
, Issue.1
, pp. 151-161
-
-
Bodiga, S.1
Zhong, J.C.2
Wang, W.3
Basu, R.4
Lo, J.5
Liu, G.C.6
-
5
-
-
78651478726
-
Epidemiology and risk profile of heart failure
-
doi:10.1038/nrcardio.2010.165. PMID:21060326
-
Bui, A.L., Horwich, T.B., and Fonarow, G.C. 2011. Epidemiology and risk profile of heart failure. Nat. Rev. Cardiol. 8(1): 30-41. doi:10.1038/nrcardio.2010.165. PMID:21060326.
-
(2011)
Nat. Rev. Cardiol
, vol.8
, Issue.1
, pp. 30-41
-
-
Bui, A.L.1
Horwich, T.B.2
Fonarow, G.C.3
-
6
-
-
1942422098
-
ACE2, a new regulator of the renin-angiotensin system
-
doi:10.1016/j.tem.2004.03.001. PMID:15109615
-
Burrell, L.M., Johnston, C.I., Tikellis, C., and Cooper, M.E. 2004. ACE2, a new regulator of the renin-angiotensin system. Trends Endocrinol. Metab. 15(4): 166-169. doi:10.1016/j.tem.2004.03.001. PMID:15109615.
-
(2004)
Trends Endocrinol. Metab.
, vol.15
, Issue.4
, pp. 166-169
-
-
Burrell, L.M.1
Johnston, C.I.2
Tikellis, C.3
Cooper, M.E.4
-
7
-
-
20044377209
-
Myocardial infarction increases ACE2 expression in rat and humans
-
discussion 322-364, doi:10.1093/eurheartj/ehi114. PMID:15671045
-
Burrell, L.M., Risvanis, J., Kubota, E., Dean, R.G., MacDonald, P.S., Lu, S., et al. 2005. Myocardial infarction increases ACE2 expression in rat and humans. Eur. Heart J. 26(4): 369-375; discussion 322-364. doi:10.1093/eurheartj/ehi114. PMID:15671045.
-
(2005)
Eur. Heart J
, vol.26
, Issue.4
, pp. 369-375
-
-
Burrell, L.M.1
Risvanis, J.2
Kubota, E.3
Dean, R.G.4
Macdonald, P.S.5
Lu, S.6
-
8
-
-
84859635766
-
Chronic kidney disease: Cardiac and renal angiotensin-converting enzyme (ACE) 2 expression in rats after subtotal nephrectomy and the effect of ACE inhibition
-
doi:10.1113/expphysiol.2011.063156. PMID:22198016
-
Burrell, L.M., Burchill, L., Dean, R.G., Griggs, K., Patel, S.K., and Velkoska, E. 2012. Chronic kidney disease: cardiac and renal angiotensin-converting enzyme (ACE) 2 expression in rats after subtotal nephrectomy and the effect of ACE inhibition. Exp. Physiol. 97(4): 477-485. doi:10.1113/expphysiol.2011.063156. PMID:22198016.
-
(2012)
Exp. Physiol
, vol.97
, Issue.4
, pp. 477-485
-
-
Burrell, L.M.1
Burchill, L.2
Dean, R.G.3
Griggs, K.4
Patel, S.K.5
Velkoska, E.6
-
9
-
-
84871878863
-
The ACE2 gene: Its potential as a functional candidate for cardiovascular disease
-
doi:10.1042/CS20120269. PMID:23013041
-
Burrell, L.M., Harrap, S.B., Velkoska, E., and Patel, S.K. 2013. The ACE2 gene: its potential as a functional candidate for cardiovascular disease. Clin. Sci. (Lond.), 124(2): 65-76. doi:10.1042/CS20120269. PMID:23013041.
-
(2013)
Clin. Sci. (Lond.)
, vol.124
, Issue.2
, pp. 65-76
-
-
Burrell, L.M.1
Harrap, S.B.2
Velkoska, E.3
Patel, S.K.4
-
10
-
-
34548851716
-
Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: More than regulation of blood pressure?
-
doi:10.1161/HYPERTENSIONAHA. 106.076216. PMID:17785634
-
Chappell, M.C. 2007. Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure? Hypertension, 50(4): 596-599. doi:10.1161/HYPERTENSIONAHA. 106.076216. PMID:17785634.
-
(2007)
Hypertension
, vol.50
, Issue.4
, pp. 596-599
-
-
Chappell, M.C.1
-
11
-
-
84891387188
-
Epigenetic regulation of angiotensin converting enzyme-2 (ACE2) by SIRT1 under conditions of cell energy stress
-
doi:10.1042/ CS20130291. PMID:24147777
-
Clarke, N.E., Belyaev, N.D., Lambert, D.W., and Turner, A.J. 2014. Epigenetic regulation of angiotensin converting enzyme-2 (ACE2) by SIRT1 under conditions of cell energy stress. Clin. Sci. (Lond.), 126(7): 507-516. doi:10.1042/ CS20130291. PMID:24147777.
-
(2014)
Clin. Sci. (Lond.)
, vol.126
, Issue.7
, pp. 507-516
-
-
Clarke, N.E.1
Belyaev, N.D.2
Lambert, D.W.3
Turner, A.J.4
-
12
-
-
0037142101
-
Angiotensin-converting enzyme 2 is an essential regulator of heart function
-
doi:10.1038/nature00786. PMID: 12075344
-
Crackower, M.A., Sarao, R., Oudit, G.Y., Yagil, C., Kozieradzki, I., Scanga, S.E., et al. 2002. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature, 417(6891): 822-828. doi:10.1038/nature00786. PMID: 12075344.
-
(2002)
Nature
, vol.417
, Issue.6891
, pp. 822-828
-
-
Crackower, M.A.1
Sarao, R.2
Oudit, G.Y.3
Yagil, C.4
Kozieradzki, I.5
Scanga, S.E.6
-
13
-
-
0029905875
-
Is there an internal cardiac renin- angiotensin system?
-
doi:10.1136/hrt.76.3_ Suppl_3.28. PMID:8983664
-
Danser, A.H., and Schalekamp, M.A. 1996. Is there an internal cardiac renin- angiotensin system? Heart, 76(3 Suppl. 3): 28-32. doi:10.1136/hrt.76.3_ Suppl_3.28. PMID:8983664.
-
(1996)
Heart
, vol.76
, Issue.3 SUPPL. 3
, pp. 28-32
-
-
Danser, A.H.1
Schalekamp, M.A.2
-
14
-
-
33344475554
-
ACE2: A novel therapeutic target for cardiovascular diseases
-
doi:10.1016/j.pbiomolbio. 2005.05.011. PMID:16009403
-
Der Sarkissian, S., Huentelman, M.J., Stewart, J., Katovich, M.J., and Raizada, M.K. 2006. ACE2: A novel therapeutic target for cardiovascular diseases. Prog. Biophys. Mol. Biol. 91(1-2): 163-198. doi:10.1016/j.pbiomolbio. 2005.05.011. PMID:16009403.
-
(2006)
Prog. Biophys. Mol. Biol
, vol.91
, Issue.1-2
, pp. 163-198
-
-
der Sarkissian, S.1
Huentelman, M.J.2
Stewart, J.3
Katovich, M.J.4
Raizada, M.K.5
-
15
-
-
39749202869
-
Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology
-
doi:10.1161/HYPERTENSIONAHA. 107.100693. PMID:18250366
-
Der Sarkissian, S., Grobe, J.L., Yuan, L., Narielwala, D.R., Walter, G.A., Katovich, M.J., and Raizada, M.K. 2008. Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology. Hypertension, 51(3): 712-718. doi:10.1161/HYPERTENSIONAHA. 107.100693. PMID:18250366.
-
(2008)
Hypertension
, vol.51
, Issue.3
, pp. 712-718
-
-
der Sarkissian, S.1
Grobe, J.L.2
Yuan, L.3
Narielwala, D.R.4
Walter, G.A.5
Katovich, M.J.6
Raizada, M.K.7
-
16
-
-
79551476911
-
Beta(2)-adrenoceptors, NADPH oxidase, ROS and p38 MAPK: Another 'radical' road to heart failure
-
doi:10.1111/j.1476-5381.2010.01130.x. PMID:21271996
-
Di Lisa, F., Kaludercic, N., and Paolocci, N. 2011. Beta(2)-adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure? Br. J. Pharmacol. 162(5): 1009-1011. doi:10.1111/j.1476-5381.2010.01130.x. PMID:21271996.
-
(2011)
Br. J. Pharmacol
, vol.162
, Issue.5
, pp. 1009-1011
-
-
Di Lisa, F.1
Kaludercic, N.2
Paolocci, N.3
-
17
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
-
doi:10.1161/01.RES.87.5.e1. PMID:10969042
-
Donoghue, M., Hsieh, F., Baronas, E., Godbout, K., Gosselin, M., Stagliano, N., et al. 2000. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ. Res. 87(5): E1-E9. doi:10.1161/01.RES.87.5.e1. PMID:10969042.
-
(2000)
Circ. Res
, vol.87
, Issue.5
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
Godbout, K.4
Gosselin, M.5
Stagliano, N.6
-
18
-
-
10744223104
-
Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins
-
doi:10.1016/S0022-2828(03)00177-9. PMID:12967627
-
Donoghue, M., Wakimoto, H., Maguire, C.T., Acton, S., Hales, P., Stagliano, N., et al. 2003. Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J. Mol. Cell. Cardiol. 35(9): 1043-1053. doi:10.1016/S0022-2828(03)00177-9. PMID:12967627.
-
(2003)
J. Mol. Cell. Cardiol
, vol.35
, Issue.9
, pp. 1043-1053
-
-
Donoghue, M.1
Wakimoto, H.2
Maguire, C.T.3
Acton, S.4
Hales, P.5
Stagliano, N.6
-
19
-
-
48049120612
-
The angiotensin-(1-7) receptor agonist AVE0991 is cardioprotective in diabetic rats
-
doi:10.1016/j.ejphar.2008.05.024. PMID:18571157
-
Ebermann, L., Spillmann, F., Sidiropoulos, M., Escher, F., Heringer-Walther, S., Schultheiss, H.P., et al. 2008. The angiotensin-(1-7) receptor agonist AVE0991 is cardioprotective in diabetic rats. Eur. J. Pharmacol. 590(1-3): 276-280. doi:10.1016/j.ejphar.2008.05.024. PMID:18571157.
-
(2008)
Eur. J. Pharmacol
, vol.590
, Issue.1-3
, pp. 276-280
-
-
Ebermann, L.1
Spillmann, F.2
Sidiropoulos, M.3
Escher, F.4
Heringer-Walther, S.5
Schultheiss, H.P.6
-
20
-
-
0035154737
-
Therapy of heart failure
-
PMID: 11527017
-
Ecder, T., Korular, D., Gurevich, A.K., Weinberger, H.D., and Schrier, R.W. 2001. Therapy of heart failure. Curr. Opin. Investig. Drugs, 2(1): 81-86. PMID: 11527017.
-
(2001)
Curr. Opin. Investig. Drugs
, vol.2
, Issue.1
, pp. 81-86
-
-
Ecder, T.1
Korular, D.2
Gurevich, A.K.3
Weinberger, H.D.4
Schrier, R.W.5
-
21
-
-
49349093061
-
Detection of soluble angiotensin-converting enzyme 2 in heart failure: Insights into the endogenous counter-regulatory pathway of the reninangiotensin- aldosterone system
-
doi:10.1016/j.jacc.2008.02.088. PMID:18718423
-
Epelman, S., Tang, W.H., Chen, S.Y., Van Lente, F., Francis, G.S., and Sen, S. 2008. Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the reninangiotensin- aldosterone system. J. Am. Coll. Cardiol. 52(9): 750-754. doi:10.1016/j.jacc.2008.02.088. PMID:18718423.
-
(2008)
J. Am. Coll. Cardiol
, vol.52
, Issue.9
, pp. 750-754
-
-
Epelman, S.1
Tang, W.H.2
Chen, S.Y.3
van Lente, F.4
Francis, G.S.5
Sen, S.6
-
22
-
-
68849105984
-
Soluble angiotensin-converting enzyme 2 in human heart failure: Relation with myocardial function and clinical outcomes
-
doi:10.1016/j.cardfail.2009.01.014. PMID:19700132
-
Epelman, S., Shrestha, K., Troughton, R.W., Francis, G.S., Sen, S., Klein, A.L., and Tang, W.H. 2009. Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes. J. Card. Fail. 15(7): 565-571. doi:10.1016/j.cardfail.2009.01.014. PMID:19700132.
-
(2009)
J. Card. Fail
, vol.15
, Issue.7
, pp. 565-571
-
-
Epelman, S.1
Shrestha, K.2
Troughton, R.W.3
Francis, G.S.4
Sen, S.5
Klein, A.L.6
Tang, W.H.7
-
23
-
-
41449089986
-
Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation
-
doi:10.1161/CIRCRESAHA.107.169110. PMID:18258853
-
Feng, Y., Yue, X., Xia, H., Bindom, S.M., Hickman, P.J., Filipeanu, C.M., et al. 2008. Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation. Circ. Res. 102(6): 729-736. doi:10.1161/CIRCRESAHA.107.169110. PMID:18258853.
-
(2008)
Circ. Res
, vol.102
, Issue.6
, pp. 729-736
-
-
Feng, Y.1
Yue, X.2
Xia, H.3
Bindom, S.M.4
Hickman, P.J.5
Filipeanu, C.M.6
-
24
-
-
76349095332
-
Brain-selective overexpression of human angiotensin-converting enzyme type 2 attenuates neurogenic hypertension
-
doi:10.1161/CIRCRESAHA.109.208645. PMID:19926873
-
Feng, Y., Xia, H., Cai, Y., Halabi, C.M., Becker, L.K., Santos, R.A., et al. 2010. Brain-selective overexpression of human angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circ. Res. 106(2): 373-382. doi:10.1161/CIRCRESAHA.109.208645. PMID:19926873.
-
(2010)
Circ. Res
, vol.106
, Issue.2
, pp. 373-382
-
-
Feng, Y.1
Xia, H.2
Cai, Y.3
Halabi, C.M.4
Becker, L.K.5
Santos, R.A.6
-
25
-
-
84869117662
-
Angiotensinconverting enzyme 2 over-expression in the central nervous system reduces angiotensin-II-mediated cardiac hypertrophy
-
doi:10.1371/journal.pone.0048910. PMID:23155428
-
Feng, Y., Hans, C., McIlwain, E., Varner, K.J., and Lazartigues, E. 2012. Angiotensinconverting enzyme 2 over-expression in the central nervous system reduces angiotensin-II-mediated cardiac hypertrophy. PloS One, 7(11): e48910. doi:10.1371/journal.pone.0048910. PMID:23155428.
-
(2012)
PloS One
, vol.7
, Issue.11
-
-
Feng, Y.1
Hans, C.2
McIlwain, E.3
Varner, K.J.4
Lazartigues, E.5
-
26
-
-
80051473367
-
Aerobic exercise training-induced left ventricular hypertrophy involves regulatory microRNAs, decreased angiotensin-converting enzyme-angiotensin II, and synergistic regulation of angiotensin-converting enzyme 2-angiotensin (1-7)
-
doi:10.1161/HYPERTENSIONAHA.110.168252. PMID:21709209
-
Fernandes, T., Hashimoto, N.Y., Magalhaes, F.C., Fernandes, F.B., Casarini, D.E., Carmona, A.K., et al. 2011. Aerobic exercise training-induced left ventricular hypertrophy involves regulatory microRNAs, decreased angiotensin-converting enzyme-angiotensin II, and synergistic regulation of angiotensin-converting enzyme 2-angiotensin (1-7). Hypertension, 58(2): 182-189. doi:10.1161/HYPERTENSIONAHA.110.168252. PMID:21709209.
-
(2011)
Hypertension
, vol.58
, Issue.2
, pp. 182-189
-
-
Fernandes, T.1
Hashimoto, N.Y.2
Magalhaes, F.C.3
Fernandes, F.B.4
Casarini, D.E.5
Carmona, A.K.6
-
27
-
-
19644384705
-
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
-
doi:10.1161/CIRCULATIONAHA.104. 510461. PMID:15897343
-
Ferrario, C.M., Jessup, J., Chappell, M.C., Averill, D.B., Brosnihan, K.B., Tallant, E.A., et al. 2005. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation, 111(20): 2605-2610. doi:10.1161/CIRCULATIONAHA.104. 510461. PMID:15897343.
-
(2005)
Circulation
, vol.111
, Issue.20
, pp. 2605-2610
-
-
Ferrario, C.M.1
Jessup, J.2
Chappell, M.C.3
Averill, D.B.4
Brosnihan, K.B.5
Tallant, E.A.6
-
28
-
-
33846956137
-
The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction
-
doi:10.1152/ajpheart.00828.2006. PMID:17056670
-
Ferreira, A.J., Jacoby, B.A., Araujo, C.A., Macedo, F.A., Silva, G.A., Almeida, A.P., et al. 2007. The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 292(2): H1113-H1119. doi:10.1152/ajpheart.00828.2006. PMID:17056670.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.292
, Issue.2
-
-
Ferreira, A.J.1
Jacoby, B.A.2
Araujo, C.A.3
Macedo, F.A.4
Silva, G.A.5
Almeida, A.P.6
-
29
-
-
84866697003
-
Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the Mas or angiotensin type 2 receptor
-
doi:10.1371/journal.pone.0045564. PMID:23029101
-
Flores-Munoz, M., Godinho, B.M., Almalik, A., and Nicklin, S.A. 2012. Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the Mas or angiotensin type 2 receptor. PloS One, 7(9): e45564. doi:10.1371/journal.pone.0045564. PMID:23029101.
-
(2012)
PloS One
, vol.7
, Issue.9
-
-
Flores-Munoz, M.1
Godinho, B.M.2
Almalik, A.3
Nicklin, S.A.4
-
30
-
-
0033183201
-
Diastolic heart failure: Identification and characterization. Epidemiology, prevalence and grounds for clinical suspicion
-
PMID:10582450
-
Goncalves, R. 1999. Diastolic heart failure: identification and characterization. Epidemiology, prevalence and grounds for clinical suspicion. Rev. Port. Cardiol. 18(Suppl. 5): V17-V18. PMID:10582450.
-
(1999)
Rev. Port. Cardiol
, vol.18
, Issue.SUPPL. 5
-
-
Goncalves, R.1
-
31
-
-
4243105120
-
ACE2 gene expression is up-regulated in the human failing heart
-
doi:10.1186/ 1741-7015-2- 9. PMID:15151696
-
Goulter, A.B., Goddard, M.J., Allen, J.C., and Clark, K.L. 2004. ACE2 gene expression is up-regulated in the human failing heart. BMC Med. 2: 19. doi:10.1186/ 1741-7015-2- 9. PMID:15151696.
-
(2004)
BMC Med
, vol.2
, pp. 19
-
-
Goulter, A.B.1
Goddard, M.J.2
Allen, J.C.3
Clark, K.L.4
-
32
-
-
73849117533
-
Angiotensin-(1-7) - angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus
-
doi:10.1161/HYPERTENSIONAHA.109.141622. PMID:19948986
-
Gwathmey, T.M., Pendergrass, K.D., Reid, S.D., Rose, J.C., Diz, D.I., and Chappell, M.C. 2010. Angiotensin-(1-7) - angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension, 55(1): 166-171. doi:10.1161/HYPERTENSIONAHA.109.141622. PMID:19948986.
-
(2010)
Hypertension
, vol.55
, Issue.1
, pp. 166-171
-
-
Gwathmey, T.M.1
Pendergrass, K.D.2
Reid, S.D.3
Rose, J.C.4
Diz, D.I.5
Chappell, M.C.6
-
33
-
-
84857856222
-
Novel roles of nuclear angiotensin receptors and signaling mechanisms
-
doi:10.1152/ ajpregu.00525.2011. PMID:22170620
-
Gwathmey, T.M., Alzayadneh, E.M., Pendergrass, K.D., and Chappell, M.C. 2012. Novel roles of nuclear angiotensin receptors and signaling mechanisms. Am. J. Physiol. Regul. Integr. Comp. Physiol. 302(5): R518-R530. doi:10.1152/ ajpregu.00525.2011. PMID:22170620.
-
(2012)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.302
, Issue.5
-
-
Gwathmey, T.M.1
Alzayadneh, E.M.2
Pendergrass, K.D.3
Chappell, M.C.4
-
34
-
-
34248597758
-
The emerging role of ACE2 in physiology and disease
-
doi:10.1002/path.2162. PMID:17464936
-
Hamming, I., Cooper, M.E., Haagmans, B.L., Hooper, N.M., Korstanje, R., Osterhaus, A.D., et al. 2007. The emerging role of ACE2 in physiology and disease. J. Pathol. 212(1): 1-11. doi:10.1002/path.2162. PMID:17464936.
-
(2007)
J. Pathol
, vol.212
, Issue.1
, pp. 1-11
-
-
Hamming, I.1
Cooper, M.E.2
Haagmans, B.L.3
Hooper, N.M.4
Korstanje, R.5
Osterhaus, A.D.6
-
35
-
-
84865806103
-
Possible involvement of angiotensin-converting enzyme 2 and Mas activation in inhibitory effects of angiotensin II type 1 receptor blockade on vascular remodeling
-
doi:10.1161/HYPERTENSIONAHA. 112.191452. PMID:22665126
-
Iwai, M., Nakaoka, H., Senba, I., Kanno, H., Moritani, T., and Horiuchi, M. 2012. Possible involvement of angiotensin-converting enzyme 2 and Mas activation in inhibitory effects of angiotensin II type 1 receptor blockade on vascular remodeling. Hypertension, 60(1): 137-144. doi:10.1161/HYPERTENSIONAHA. 112.191452. PMID:22665126.
-
(2012)
Hypertension
, vol.60
, Issue.1
, pp. 137-144
-
-
Iwai, M.1
Nakaoka, H.2
Senba, I.3
Kanno, H.4
Moritani, T.5
Horiuchi, M.6
-
36
-
-
27644585370
-
Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients
-
doi:10.1161/01.RES.0000187500.24964.7A. PMID:16179584
-
Keidar, S., Gamliel-Lazarovich, A., Kaplan, M., Pavlotzky, E., Hamoud, S., Hayek, T., et al. 2005. Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients. Circ. Res. 97(9): 946-953. doi:10.1161/01.RES.0000187500.24964.7A. PMID:16179584.
-
(2005)
Circ. Res
, vol.97
, Issue.9
, pp. 946-953
-
-
Keidar, S.1
Gamliel-Lazarovich, A.2
Kaplan, M.3
Pavlotzky, E.4
Hamoud, S.5
Hayek, T.6
-
37
-
-
33846256550
-
ACE2 of the heart: From angiotensin I to angiotensin (1-7)
-
doi:10.1016/ j.cardiores.2006.09.006. PMID:17049503
-
Keidar, S., Kaplan, M., and Gamliel-Lazarovich, A. 2007. ACE2 of the heart: From angiotensin I to angiotensin (1-7). Cardiovasc. Res. 73(3): 463-469. doi:10.1016/ j.cardiores.2006.09.006. PMID:17049503.
-
(2007)
Cardiovasc. Res
, vol.73
, Issue.3
, pp. 463-469
-
-
Keidar, S.1
Kaplan, M.2
Gamliel-Lazarovich, A.3
-
38
-
-
84866041941
-
The pathophysiology of heart failure
-
doi:10.1016/j.carpath.2011.11.007. PMID:22227365
-
Kemp, C.D., and Conte, J.V. 2012. The pathophysiology of heart failure. Cardiovasc. Pathol. 21(5): 365-371. doi:10.1016/j.carpath.2011.11.007. PMID:22227365.
-
(2012)
Cardiovasc. Pathol
, vol.21
, Issue.5
, pp. 365-371
-
-
Kemp, C.D.1
Conte, J.V.2
-
39
-
-
21344442672
-
Gene expression analysis of ischemic and nonischemic cardiomyopathy: Shared and distinct genes in the development of heart failure
-
doi:10.1152/physiolgenomics.00255.2004. PMID: 15769906
-
Kittleson, M.M., Minhas, K.M., Irizarry, R.A., Ye, S.Q., Edness, G., Breton, E., et al. 2005. Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure. Physiol. Genomics, 21(3): 299-307. doi:10.1152/physiolgenomics.00255.2004. PMID: 15769906.
-
(2005)
Physiol. Genomics
, vol.21
, Issue.3
, pp. 299-307
-
-
Kittleson, M.M.1
Minhas, K.M.2
Irizarry, R.A.3
Ye, S.Q.4
Edness, G.5
Breton, E.6
-
40
-
-
84880778204
-
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats
-
doi:10. 1007/s00408-013-9470-8. PMID:23652350
-
Li, G., Liu, Y., Zhu, Y., Liu, A., Xu, Y., Li, X., et al. 2013. ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats. Lung, 191(4): 327-336. doi:10. 1007/s00408-013-9470-8. PMID:23652350.
-
(2013)
Lung
, vol.191
, Issue.4
, pp. 327-336
-
-
Li, G.1
Liu, Y.2
Zhu, Y.3
Liu, A.4
Xu, Y.5
Li, X.6
-
41
-
-
3242769190
-
Involvement of chymase-mediated angiotensin II generation in blood pressure regulation
-
doi:10.1172/JCI200420805. PMID:15232618
-
Li, M., Liu, K., Michalicek, J., Angus, J.A., Hunt, J.E., Dell'Italia, L.J., et al. 2004. Involvement of chymase-mediated angiotensin II generation in blood pressure regulation. J. Clin. Invest. 114(1): 112-120. doi:10.1172/JCI200420805. PMID:15232618.
-
(2004)
J. Clin. Invest
, vol.114
, Issue.1
, pp. 112-120
-
-
Li, M.1
Liu, K.2
Michalicek, J.3
Angus, J.A.4
Hunt, J.E.5
Dell'italia, L.J.6
-
42
-
-
84864934564
-
Angiotensin-(1-7) suppresses oxidative stress and improves glucose uptake via Mas receptor in adipocytes
-
doi:10.1007/s00592-011-0348-z. PMID:22042130
-
Liu, C., Lv, X.H., Li, H.X., Cao, X., Zhang, F., Wang, L., et al. 2012. Angiotensin-(1-7) suppresses oxidative stress and improves glucose uptake via Mas receptor in adipocytes. Acta Diabetol. 49(4): 291-299. doi:10.1007/s00592-011-0348-z. PMID:22042130.
-
(2012)
Acta Diabetol
, vol.49
, Issue.4
, pp. 291-299
-
-
Liu, C.1
Lv, X.H.2
Li, H.X.3
Cao, X.4
Zhang, F.5
Wang, L.6
-
43
-
-
84880110094
-
Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17beta-oestradiol-dependent and sex chromosome-independent
-
doi:10.1186/2042-6410-1-6. PMID:21208466
-
Liu, J., Ji, H., Zheng, W., Wu, X., Zhu, J.J., Arnold, A.P., and Sandberg, K. 2010. Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17beta-oestradiol-dependent and sex chromosome-independent. Biol. Sex Differ. 1(1): 6. doi:10.1186/2042-6410-1-6. PMID:21208466.
-
(2010)
Biol. Sex Differ
, vol.1
, Issue.1
, pp. 6
-
-
Liu, J.1
Ji, H.2
Zheng, W.3
Wu, X.4
Zhu, J.J.5
Arnold, A.P.6
Sandberg, K.7
-
44
-
-
84872178401
-
Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats
-
doi:10.1113/expphysiol.2012.067165. PMID:22750422
-
Lo, J., Patel, V.B., Wang, Z., Levasseur, J., Kaufman, S., Penninger, J.M., and Oudit, G.Y. 2013. Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats. Exp. Physiol. 98(1): 109-122. doi:10.1113/expphysiol.2012.067165. PMID:22750422.
-
(2013)
Exp. Physiol
, vol.98
, Issue.1
, pp. 109-122
-
-
Lo, J.1
Patel, V.B.2
Wang, Z.3
Levasseur, J.4
Kaufman, S.5
Penninger, J.M.6
Oudit, G.Y.7
-
45
-
-
0037007055
-
Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats
-
doi:10.1161/01.CIR.0000013847.07035.B9. PMID:11927520
-
Loot, A.E., Roks, A.J., Henning, R.H., Tio, R.A., Suurmeijer, A.J., Boomsma, F., and van Gilst, W.H. 2002. Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats. Circulation, 105(13): 1548-1550. doi:10.1161/01.CIR.0000013847.07035.B9. PMID:11927520.
-
(2002)
Circulation
, vol.105
, Issue.13
, pp. 1548-1550
-
-
Loot, A.E.1
Roks, A.J.2
Henning, R.H.3
Tio, R.A.4
Suurmeijer, A.J.5
Boomsma, F.6
van Gilst, W.H.7
-
46
-
-
57049183645
-
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis
-
doi: 10.1152/ajpheart.00331.2008. PMID:18660448
-
Lovren, F., Pan, Y., Quan, A., Teoh, H., Wang, G., Shukla, P.C., et al. 2008. Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am. J. Physiol. Heart Circ. Physiol. 295(4): H1377-H1384. doi: 10.1152/ajpheart.00331.2008. PMID:18660448.
-
(2008)
Am. J. Physiol. Heart Circ. Physiol
, vol.295
, Issue.4
-
-
Lovren, F.1
Pan, Y.2
Quan, A.3
Teoh, H.4
Wang, G.5
Shukla, P.C.6
-
47
-
-
79959866121
-
Angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and combined therapy in patients with micro- and macroalbuminuria and other cardiovascular risk factors: A systematic review of randomized controlled trials
-
doi:10.1093/ndt/ gfq792. PMID:21372254
-
Maione, A., Navaneethan, S.D., Graziano, G., Mitchell, R., Johnson, D., Mann, J.F., et al. 2011. Angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and combined therapy in patients with micro- and macroalbuminuria and other cardiovascular risk factors: a systematic review of randomized controlled trials. Nephrol. Dial. Transplant. 26(9): 2827-2847. doi:10.1093/ndt/ gfq792. PMID:21372254.
-
(2011)
Nephrol. Dial. Transplant
, vol.26
, Issue.9
, pp. 2827-2847
-
-
Maione, A.1
Navaneethan, S.D.2
Graziano, G.3
Mitchell, R.4
Johnson, D.5
Mann, J.F.6
-
48
-
-
74849098087
-
Clinical practice. Systolic heart failure
-
doi:10.1056/NEJMcp0909392. PMID:20089973
-
McMurray, J.J. 2010. Clinical practice. Systolic heart failure. N. Engl. J. Med. 362(3): 228-238. doi:10.1056/NEJMcp0909392. PMID:20089973.
-
(2010)
N. Engl. J. Med
, vol.362
, Issue.3
, pp. 228-238
-
-
McMurray, J.J.1
-
49
-
-
80051990993
-
CONSENSUS to EMPHASIS: The overwhelming evidence which makes blockade of the renin-angiotensin-aldosterone system the cornerstone of therapy for systolic heart failure
-
doi:10.1093/eurjhf/hfr093. PMID:21816763
-
McMurray, J.J. 2011. CONSENSUS to EMPHASIS: the overwhelming evidence which makes blockade of the renin-angiotensin-aldosterone system the cornerstone of therapy for systolic heart failure. Eur. J. Heart Fail. 13(9): 929-936. doi:10.1093/eurjhf/hfr093. PMID:21816763.
-
(2011)
Eur. J. Heart Fail
, vol.13
, Issue.9
, pp. 929-936
-
-
McMurray, J.J.1
-
50
-
-
70350510296
-
Effects of angiotensin-converting enzyme inhibitor therapy on clinical outcome in patients undergoing coronary artery bypass grafting
-
doi:10.1016/j.jacc.2009.07.008. PMID: 19682819
-
Miceli, A., Capoun, R., Fino, C., Narayan, P., Bryan, A.J., Angelini, G.D., and Caputo, M. 2009. Effects of angiotensin-converting enzyme inhibitor therapy on clinical outcome in patients undergoing coronary artery bypass grafting. J. Am. Coll. Cardiol. 54(19): 1778-1784. doi:10.1016/j.jacc.2009.07.008. PMID: 19682819.
-
(2009)
J. Am. Coll. Cardiol
, vol.54
, Issue.19
, pp. 1778-1784
-
-
Miceli, A.1
Capoun, R.2
Fino, C.3
Narayan, P.4
Bryan, A.J.5
Angelini, G.D.6
Caputo, M.7
-
51
-
-
84881507866
-
Impact of the renin- angiotensin system on cardiac energy metabolism in heart failure
-
doi:10.1016/j.yjmcc.2013.07.010. PMID:23886814
-
Mori, J., Zhang, L., Oudit, G.Y., and Lopaschuk, G.D. 2013. Impact of the renin- angiotensin system on cardiac energy metabolism in heart failure. J. Mol. Cell. Cardiol. 63: 98-106. doi:10.1016/j.yjmcc.2013.07.010. PMID:23886814.
-
(2013)
J. Mol. Cell. Cardiol
, vol.63
, pp. 98-106
-
-
Mori, J.1
Zhang, L.2
Oudit, G.Y.3
Lopaschuk, G.D.4
-
52
-
-
34548184904
-
Clinical epidemiology of heart failure
-
doi:10.1136/hrt.2003.025270. PMID:17699180
-
Mosterd, A., and Hoes, A.W. 2007. Clinical epidemiology of heart failure. Heart, 93(9): 1137-1146. doi:10.1136/hrt.2003.025270. PMID:17699180.
-
(2007)
Heart
, vol.93
, Issue.9
, pp. 1137-1146
-
-
Mosterd, A.1
Hoes, A.W.2
-
53
-
-
84862630741
-
Chronic activation of endogenous angiotensin-converting enzyme 2 protects diabetic rats from ardiovascular autonomic dysfunction
-
doi:10.1113/expphysiol.2011.063461. PMID:22286369
-
Murca, T.M., Almeida, T.C., Raizada, M.K., and Ferreira, A.J. 2012. Chronic activation of endogenous angiotensin-converting enzyme 2 protects diabetic rats from ardiovascular autonomic dysfunction. Exp. Physiol. 97(6): 699-709. doi:10.1113/expphysiol.2011.063461. PMID:22286369.
-
(2012)
Exp. Physiol
, vol.97
, Issue.6
, pp. 699-709
-
-
Murca, T.M.1
Almeida, T.C.2
Raizada, M.K.3
Ferreira, A.J.4
-
54
-
-
0242440725
-
Epidemiology and clinical aspects of congestive heart failure
-
doi:10.3317/jraas.2003.020. PMID:14608515
-
Murray-Thomas, T., and Cowie, M.R. 2003. Epidemiology and clinical aspects of congestive heart failure. J. Renin Angiotensin Aldosterone Syst. 4(3): 131-136. doi:10.3317/jraas.2003.020. PMID:14608515.
-
(2003)
J. Renin Angiotensin Aldosterone Syst
, vol.4
, Issue.3
, pp. 131-136
-
-
Murray-Thomas, T.1
Cowie, M.R.2
-
55
-
-
80055049289
-
Recombinant human angiotensinconverting enzyme 2 as a new renin-angiotensin system peptidase for heart failure therapy
-
doi:10.1007/s11897-011- 0063-7. PMID:21611889
-
Oudit, G.Y., and Penninger, J.M. 2011. Recombinant human angiotensinconverting enzyme 2 as a new renin-angiotensin system peptidase for heart failure therapy. Curr. Heart Fail. Rep. 8(3): 176-183. doi:10.1007/s11897-011- 0063-7. PMID:21611889.
-
(2011)
Curr. Heart Fail. Rep
, vol.8
, Issue.3
, pp. 176-183
-
-
Oudit, G.Y.1
Penninger, J.M.2
-
56
-
-
0037383515
-
The role of ACE2 in cardiovascular physiology
-
doi:10.1016/S1050-1738(02)00233-5. PMID:12691672
-
Oudit, G.Y., Crackower, M.A., Backx, P.H., and Penninger, J.M. 2003. The role of ACE2 in cardiovascular physiology. Trends Cardiovasc. Med. 13(3): 93-101. doi:10.1016/S1050-1738(02)00233-5. PMID:12691672.
-
(2003)
Trends Cardiovasc. Med
, vol.13
, Issue.3
, pp. 93-101
-
-
Oudit, G.Y.1
Crackower, M.A.2
Backx, P.H.3
Penninger, J.M.4
-
57
-
-
34249900226
-
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice
-
doi:10.1016/j.cardiores.2007.04.007. PMID:17499227
-
Oudit, G.Y., Kassiri, Z., Patel, M.P., Chappell, M., Butany, J., Backx, P.H., et al. 2007. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc. Res. 75(1): 29-39. doi:10.1016/j.cardiores.2007.04.007. PMID:17499227.
-
(2007)
Cardiovasc. Res
, vol.75
, Issue.1
, pp. 29-39
-
-
Oudit, G.Y.1
Kassiri, Z.2
Patel, M.P.3
Chappell, M.4
Butany, J.5
Backx, P.H.6
-
58
-
-
66849134954
-
SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
-
doi:10.1111/j.1365-2362.2009.02153.x. PMID:19453650
-
Oudit, G.Y., Kassiri, Z., Jiang, C., Liu, P.P., Poutanen, S.M., Penninger, J.M., and Butany, J. 2009. SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS. Eur. J. Clin. Invest. 39(7): 618-625. doi:10.1111/j.1365-2362.2009.02153.x. PMID:19453650.
-
(2009)
Eur. J. Clin. Invest
, vol.39
, Issue.7
, pp. 618-625
-
-
Oudit, G.Y.1
Kassiri, Z.2
Jiang, C.3
Liu, P.P.4
Poutanen, S.M.5
Penninger, J.M.6
Butany, J.7
-
59
-
-
84861528870
-
Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensinconverting enzyme 2-null mice
-
doi:10.1161/ HYPERTENSIONAHA.112.191650. PMID:22508831
-
Patel, V.B., Bodiga, S., Fan, D., Das, S.K., Wang, Z., Wang, W., et al. 2012. Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensinconverting enzyme 2-null mice. Hypertension, 59(6): 1195-1203. doi:10.1161/ HYPERTENSIONAHA.112.191650. PMID:22508831.
-
(2012)
Hypertension
, vol.59
, Issue.6
, pp. 1195-1203
-
-
Patel, V.B.1
Bodiga, S.2
Fan, D.3
Das, S.K.4
Wang, Z.5
Wang, W.6
-
60
-
-
84891683755
-
Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS
-
doi:10.1016/j.yjmcc.2013.11.017. PMID:24332999
-
Patel, V.B., Clarke, N., Wang, Z., Fan, D., Parajuli, N., Basu, R., et al. 2014. Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS. J. Mol. Cell. Cardiol. 66: 167-176. doi:10.1016/j.yjmcc.2013.11.017. PMID:24332999.
-
(2014)
J. Mol. Cell. Cardiol
, vol.66
, pp. 167-176
-
-
Patel, V.B.1
Clarke, N.2
Wang, Z.3
Fan, D.4
Parajuli, N.5
Basu, R.6
-
61
-
-
0027264868
-
Gene expression of the renin- angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction
-
doi:10.1172/JCI116428. PMID:8387539
-
Paul, M., Wagner, J., and Dzau, V.J. 1993. Gene expression of the renin- angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. J. Clin. Invest. 91(5): 2058-2064. doi:10.1172/JCI116428. PMID:8387539.
-
(1993)
J. Clin. Invest
, vol.91
, Issue.5
, pp. 2058-2064
-
-
Paul, M.1
Wagner, J.2
Dzau, V.J.3
-
62
-
-
33745845825
-
Physiology of local renin- angiotensin systems
-
doi:10.1152/physrev.00036. 2005. PMID:16816138
-
Paul, M., Poyan Mehr, A., and Kreutz, R. 2006. Physiology of local renin- angiotensin systems. Physiol. Rev. 86(3): 747-803. doi:10.1152/physrev.00036. 2005. PMID:16816138.
-
(2006)
Physiol. Rev
, vol.86
, Issue.3
, pp. 747-803
-
-
Paul, M.1
Poyan Mehr, A.2
Kreutz, R.3
-
63
-
-
84888061271
-
ACE2 - From the renin-angiotensin system to gut microbiota and malnutrition
-
doi:10.1016/j.micinf.2013.08.003. PMID:23962453
-
Perlot, T., and Penninger, J.M. 2013. ACE2 - From the renin-angiotensin system to gut microbiota and malnutrition. Microbes Infect. 15(13): 866-873. doi:10.1016/j.micinf.2013.08.003. PMID:23962453.
-
(2013)
Microbes Infect
, vol.15
, Issue.13
, pp. 866-873
-
-
Perlot, T.1
Penninger, J.M.2
-
64
-
-
0034560074
-
Systolic versus diastolic heart failure in community practice: Clinical features, outcomes, and the use of angiotensin-converting enzyme inhibitors
-
doi:10.1016/S0002-9343(00)00601-X. PMID: 11099679
-
Philbin, E.F., Rocco, T.A., Jr., Lindenmuth, N.W., Ulrich, K., and Jenkins, P.L. 2000. Systolic versus diastolic heart failure in community practice: clinical features, outcomes, and the use of angiotensin-converting enzyme inhibitors. Am. J. Med. 109(8): 605-613. doi:10.1016/S0002-9343(00)00601-X. PMID: 11099679.
-
(2000)
Am. J. Med
, vol.109
, Issue.8
, pp. 605-613
-
-
Philbin, E.F.1
Rocco Jr., T.A.2
Lindenmuth, N.W.3
Ulrich, K.4
Jenkins, P.L.5
-
65
-
-
80051949470
-
Lentivirusmediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology
-
doi:10.1113/expphysiol. 2011.056994. PMID:21685447
-
Qi, Y., Shenoy, V., Wong, F., Li, H., Afzal, A., Mocco, J., et al. 2011. Lentivirusmediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology. Exp. Physiol. 96(9): 863-874. doi:10.1113/expphysiol. 2011.056994. PMID:21685447.
-
(2011)
Exp. Physiol
, vol.96
, Issue.9
, pp. 863-874
-
-
Qi, Y.1
Shenoy, V.2
Wong, F.3
Li, H.4
Afzal, A.5
Mocco, J.6
-
66
-
-
55949126600
-
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
-
doi:10.1161/HYPERTENSIONAHA.108.114322. PMID:18809792
-
Rentzsch, B., Todiras, M., Iliescu, R., Popova, E., Campos, L.A., Oliveira, M.L., et al. 2008. Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension, 52(5): 967-973. doi:10.1161/HYPERTENSIONAHA.108.114322. PMID:18809792.
-
(2008)
Hypertension
, vol.52
, Issue.5
, pp. 967-973
-
-
Rentzsch, B.1
Todiras, M.2
Iliescu, R.3
Popova, E.4
Campos, L.A.5
Oliveira, M.L.6
-
67
-
-
84883569291
-
Epidemiology of heart failure
-
doi: 10.1161/CIRCRESAHA.113.300268. PMID:23989710
-
Roger, V.L. 2013. Epidemiology of heart failure. Circ. Res. 113(6): 646-659. doi: 10.1161/CIRCRESAHA.113.300268. PMID:23989710.
-
(2013)
Circ. Res
, vol.113
, Issue.6
, pp. 646-659
-
-
Roger, V.L.1
-
68
-
-
0037478671
-
Angiotensin-(1-7) is an endogenous ligand for the G proteincoupled receptor Mas
-
doi:10.1073/pnas.1432869100. PMID:12829792
-
Santos, R.A., Simoes e Silva, A.C., Maric, C., Silva, D.M., Machado, R.P., de Buhr, I., et al. 2003. Angiotensin-(1-7) is an endogenous ligand for the G proteincoupled receptor Mas. Proc. Natl. Acad. Sci. U.S.A. 100(14): 8258-8263. doi:10.1073/pnas.1432869100. PMID:12829792.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, Issue.14
, pp. 8258-8263
-
-
Santos, R.A.1
Simoes e Silva, A.C.2
Maric, C.3
Silva, D.M.4
Machado, R.P.5
de Buhr, I.6
-
69
-
-
84890090677
-
Apelin is a positive regulator of ACE2 in failing hearts
-
doi:10.1172/JCI69608. PMID:24177423
-
Sato, T., Suzuki, T., Watanabe, H., Kadowaki, A., Fukamizu, A., Liu, P.P., et al. 2013. Apelin is a positive regulator of ACE2 in failing hearts. J. Clin. Invest. 123(12): 5203-5211. doi:10.1172/JCI69608. PMID:24177423.
-
(2013)
J. Clin. Invest
, vol.123
, Issue.12
, pp. 5203-5211
-
-
Sato, T.1
Suzuki, T.2
Watanabe, H.3
Kadowaki, A.4
Fukamizu, A.5
Liu, P.P.6
-
70
-
-
0034111224
-
Therapy of heart failure
-
doi:10.1046/j.1523-1755.2000.00986.x. PMID:10760077
-
Schrier, R.W., Abdallah, J.G., Weinberger, H.H., and Abraham, W.T. 2000. Therapy of heart failure. Kidney Int. 57(4): 1418-1425. doi:10.1046/j.1523-1755.2000.00986.x. PMID:10760077.
-
(2000)
Kidney Int
, vol.57
, Issue.4
, pp. 1418-1425
-
-
Schrier, R.W.1
Abdallah, J.G.2
Weinberger, H.H.3
Abraham, W.T.4
-
71
-
-
80051968584
-
Heart failure. 1. In search of new therapeutic targets and strategies for heart failure: Recent advances in basic science
-
doi:10.1016/S0140-6736(11)60894-5. PMID:21856484
-
Shah, A.M., and Mann, D.L. 2011. Heart failure. 1. In search of new therapeutic targets and strategies for heart failure: recent advances in basic science. Lancet, 378(9792): 704-712. doi:10.1016/S0140-6736(11)60894-5. PMID:21856484.
-
(2011)
Lancet
, vol.378
, Issue.9792
, pp. 704-712
-
-
Shah, A.M.1
Mann, D.L.2
-
72
-
-
84877823830
-
ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis
-
doi:10.1111/bph.12159. PMID:23488800
-
Simoes e Silva, A.C., Silveira, K.D., Ferreira, A.J., and Teixeira, M.M. 2013. ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis. Br. J. Pharmacol. 169(3): 477-492. doi:10.1111/bph.12159. PMID:23488800.
-
(2013)
Br. J. Pharmacol
, vol.169
, Issue.3
, pp. 477-492
-
-
Simoes e Silva, A.C.1
Silveira, K.D.2
Ferreira, A.J.3
Teixeira, M.M.4
-
73
-
-
84880584666
-
Angiotensinconverting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways
-
doi:10.1016/j.regpep.2013.06.007. PMID:23816468
-
Song, B., Jin, H., Yu, X., Zhang, Z., Yu, H., Ye, J., et al. 2013. Angiotensinconverting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways. Regul. Pept. 185C: 44-51. doi:10.1016/j.regpep.2013.06.007. PMID:23816468.
-
(2013)
Regul. Pept
, vol.185 C
, pp. 44-51
-
-
Song, B.1
Jin, H.2
Yu, X.3
Zhang, Z.4
Yu, H.5
Ye, J.6
-
74
-
-
0025088737
-
Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortalitys
-
doi:10.1161/01.CIR.82.5.1730. PMID:2225374, CONSENSUS Trial Study Group
-
Swedberg, K., Eneroth, P., Kjekshus, J., and Wilhelmsen, L. 1990. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. Circulation, 82(5): 1730-1736. doi:10.1161/01.CIR.82.5.1730. PMID:2225374.
-
(1990)
Circulation
, vol.82
, Issue.5
, pp. 1730-1736
-
-
Swedberg, K.1
Eneroth, P.2
Kjekshus, J.3
Wilhelmsen, L.4
-
75
-
-
77953328985
-
Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy
-
doi:10.1159/000314924. PMID:20551625
-
Thallas-Bonke, V., Coughlan, M.T., Bach, L.A., Cooper, M.E., and Forbes, J.M. 2010. Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme in diabetic nephropathy. Am. J. Nephrol. 32(1): 73-82. doi:10.1159/000314924. PMID:20551625.
-
(2010)
Am. J. Nephrol
, vol.32
, Issue.1
, pp. 73-82
-
-
Thallas-Bonke, V.1
Coughlan, M.T.2
Bach, L.A.3
Cooper, M.E.4
Forbes, J.M.5
-
76
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
doi:10.1074/jbc.M002615200. PMID:10924499
-
Tipnis, S.R., Hooper, N.M., Hyde, R., Karran, E., Christie, G., and Turner, A.J. 2000. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J. Biol. Chem. 275(43): 33238-33243. doi:10.1074/jbc.M002615200. PMID:10924499.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.43
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turner, A.J.6
-
77
-
-
84862648459
-
Role of ACE2 in diastolic and systolic heart failure
-
doi:10.1007/s10741-011-9259-x. PMID:21638102
-
Wang, W., Bodiga, S., Das, S.K., Lo, J., Patel, V., and Oudit, G.Y. 2011. Role of ACE2 in diastolic and systolic heart failure. Heart Fail. Rev. 17(4): 683-691. doi:10.1007/s10741-011-9259-x. PMID:21638102.
-
(2011)
Heart Fail. Rev
, vol.17
, Issue.4
, pp. 683-691
-
-
Wang, W.1
Bodiga, S.2
Das, S.K.3
Lo, J.4
Patel, V.5
Oudit, G.Y.6
-
78
-
-
27944467680
-
Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells
-
doi:10.1074/jbc.M508914200. PMID:16166094
-
Warner, F.J., Lew, R.A., Smith, A.I., Lambert, D.W., Hooper, N.M., and Turner, A.J. 2005. Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells. J. Biol. Chem. 280(47): 39353-39362. doi:10.1074/jbc.M508914200. PMID:16166094.
-
(2005)
J. Biol. Chem
, vol.280
, Issue.47
, pp. 39353-39362
-
-
Warner, F.J.1
Lew, R.A.2
Smith, A.I.3
Lambert, D.W.4
Hooper, N.M.5
Turner, A.J.6
-
79
-
-
77951171609
-
Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents
-
doi:10.1172/JCI39345. PMID:20335663
-
Wei, C.C., Hase, N., Inoue, Y., Bradley, E.W., Yahiro, E., Li, M., et al. 2010. Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents. J. Clin. Invest. 120(4): 1229-1239. doi:10.1172/JCI39345. PMID:20335663.
-
(2010)
J. Clin. Invest
, vol.120
, Issue.4
, pp. 1229-1239
-
-
Wei, C.C.1
Hase, N.2
Inoue, Y.3
Bradley, E.W.4
Yahiro, E.5
Li, M.6
-
80
-
-
38949093861
-
Angiotensin II-induced skeletal muscle insulin resistance mediated by NFkappaB activation via NADPH oxidase
-
doi:10.1152/ajpendo.00456.2007. PMID:18073321
-
Wei, Y., Sowers, J.R., Clark, S.E., Li, W., Ferrario, C.M., and Stump, C.S. 2008. Angiotensin II-induced skeletal muscle insulin resistance mediated by NFkappaB activation via NADPH oxidase. Am. J. Physiol. Endocrinol. Metab. 294(2): E345-E351. doi:10.1152/ajpendo.00456.2007. PMID:18073321.
-
(2008)
Am. J. Physiol. Endocrinol. Metab
, vol.294
, Issue.2
-
-
Wei, Y.1
Sowers, J.R.2
Clark, S.E.3
Li, W.4
Ferrario, C.M.5
Stump, C.S.6
-
81
-
-
78650576524
-
Feeding blueberry diets inhibits angiotensin II-converting enzyme (ACE) activity in spontaneously hypertensive stroke-prone rats
-
doi:10.1139/Y10- 101. PMID:21186379
-
Wiseman, W., Egan, J.M., Slemmer, J.E., Shaughnessy, K.S., Ballem, K., Gottschall-Pass, K.T., and Sweeney, M.I. 2011. Feeding blueberry diets inhibits angiotensin II-converting enzyme (ACE) activity in spontaneously hypertensive stroke-prone rats. Can. J. Physiol. Pharmacol. 89(1): 67-71. doi:10.1139/Y10- 101. PMID:21186379.
-
(2011)
Can. J. Physiol. Pharmacol
, vol.89
, Issue.1
, pp. 67-71
-
-
Wiseman, W.1
Egan, J.M.2
Slemmer, J.E.3
Shaughnessy, K.S.4
Ballem, K.5
Gottschall-Pass, K.T.6
Sweeney, M.I.7
-
82
-
-
73849101073
-
Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: Prevention of angiotensin II-dependent hypertension
-
doi:10.1161/HYPERTENSIONAHA. 109.138420. PMID:19948988
-
Wysocki, J., Ye, M., Rodriguez, E., Gonzalez-Pacheco, F.R., Barrios, C., Evora, K., et al. 2010. Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension. Hypertension, 55(1): 90-98. doi:10.1161/HYPERTENSIONAHA. 109.138420. PMID:19948988.
-
(2010)
Hypertension
, vol.55
, Issue.1
, pp. 90-98
-
-
Wysocki, J.1
Ye, M.2
Rodriguez, E.3
Gonzalez-Pacheco, F.R.4
Barrios, C.5
Evora, K.6
-
83
-
-
56749182432
-
Angiotensin-converting enzyme 2 in the brain: Properties and future directions
-
doi:10.1111/ j.1471-4159.2008.05723.x. PMID:19014390
-
Xia, H., and Lazartigues, E. 2008. Angiotensin-converting enzyme 2 in the brain: properties and future directions. J. Neurochem. 107(6): 1482-1494. doi:10.1111/ j.1471-4159.2008.05723.x. PMID:19014390.
-
(2008)
J. Neurochem
, vol.107
, Issue.6
, pp. 1482-1494
-
-
Xia, H.1
Lazartigues, E.2
-
84
-
-
79960810124
-
ACE2- mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function
-
doi:10.1371/journal.pone.0022682. PMID:21818366
-
Xia, H., Suda, S., Bindom, S., Feng, Y., Gurley, S.B., Seth, D., et al. 2011. ACE2- mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PloS One, 6(7): e22682. doi:10.1371/journal.pone.0022682. PMID:21818366.
-
(2011)
PloS One
, vol.6
, Issue.7
-
-
Xia, H.1
Suda, S.2
Bindom, S.3
Feng, Y.4
Gurley, S.B.5
Seth, D.6
-
85
-
-
33645834948
-
Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II
-
doi:10.1161/01.HYP.0000205833.89478.5b. PMID: 16505206
-
Yamamoto, K., Ohishi, M., Katsuya, T., Ito, N., Ikushima, M., Kaibe, M., et al. 2006. Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension, 47(4): 718-726. doi:10.1161/01.HYP.0000205833.89478.5b. PMID: 16505206.
-
(2006)
Hypertension
, vol.47
, Issue.4
, pp. 718-726
-
-
Yamamoto, K.1
Ohishi, M.2
Katsuya, T.3
Ito, N.4
Ikushima, M.5
Kaibe, M.6
-
86
-
-
84885845957
-
2013 ACCF/AHA guideline for the management of heart failure: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines
-
doi:10.1161/CIR.0b013e31829e8776. PMID:23741058
-
Yancy, C.W., Jessup, M., Bozkurt, B., Butler, J., Casey, D.E., Jr., Drazner, M.H., et al. 2013. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation, 128(16): e240-e319. doi:10.1161/CIR.0b013e31829e8776. PMID:23741058.
-
(2013)
Circulation
, vol.128
, Issue.16
-
-
Yancy, C.W.1
Jessup, M.2
Bozkurt, B.3
Butler, J.4
Casey Jr., D.E.5
Drazner, M.H.6
-
87
-
-
0035960630
-
Global burden of cardiovascular diseases: Part I: General considerations, the epidemiologic transition, risk factors, and impact of urbanization
-
doi:10.1161/hc4601.099487. PMID:11723030
-
Yusuf, S., Reddy, S., Ounpuu, S., and Anand, S. 2001a. Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation, 104(22): 2746-2753. doi:10.1161/hc4601.099487. PMID:11723030.
-
(2001)
Circulation
, vol.104
, Issue.22
, pp. 2746-2753
-
-
Yusuf, S.1
Reddy, S.2
Ounpuu, S.3
Anand, S.4
-
88
-
-
0035808005
-
Global burden of cardiovascular diseases: Part II: Variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies
-
doi:10.1161/hc4701.099488. PMID:11733407
-
Yusuf, S., Reddy, S., Ounpuu, S., and Anand, S. 2001b. Global burden of cardiovascular diseases: Part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies. Circulation, 104(23): 2855-2864. doi:10.1161/hc4701.099488. PMID:11733407.
-
(2001)
Circulation
, vol.104
, Issue.23
, pp. 2855-2864
-
-
Yusuf, S.1
Reddy, S.2
Ounpuu, S.3
Anand, S.4
-
89
-
-
77957665281
-
Angiotensin-converting enzyme 2 attenuates atherosclerotic lesions by targeting vascular cells
-
doi:10.1073/pnas.1001253107. PMID:20798044
-
Zhang, C., Zhao, Y.X., Zhang, Y.H., Zhu, L., Deng, B.P., Zhou, Z.L., et al. 2010. Angiotensin-converting enzyme 2 attenuates atherosclerotic lesions by targeting vascular cells. Proc. Natl. Acad. Sci. U.S.A. 107(36): 15886-15891. doi:10.1073/pnas.1001253107. PMID:20798044.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, Issue.36
, pp. 15886-15891
-
-
Zhang, C.1
Zhao, Y.X.2
Zhang, Y.H.3
Zhu, L.4
Deng, B.P.5
Zhou, Z.L.6
-
90
-
-
37849022694
-
Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression
-
doi:10.1038/sj.bjp.0707482. PMID: 17906677
-
Zhong, J.C., Yu, X.Y., Lin, Q.X., Li, X.H., Huang, X.Z., Xiao, D.Z., and Lin, S.G. 2008. Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression. Br. J. Pharmacol. 153(1): 66-74. doi:10.1038/sj.bjp.0707482. PMID: 17906677.
-
(2008)
Br. J. Pharmacol
, vol.153
, Issue.1
, pp. 66-74
-
-
Zhong, J.C.1
Yu, X.Y.2
Lin, Q.X.3
Li, X.H.4
Huang, X.Z.5
Xiao, D.Z.6
Lin, S.G.7
-
91
-
-
77955981900
-
Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction
-
doi:10.1161/CIRCULATIONAHA.110.955369. PMID:20679547
-
Zhong, J., Basu, R., Guo, D., Chow, F.L., Byrns, S., Schuster, M., et al. 2010. Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. Circulation, 122(7): 717-728. doi:10.1161/CIRCULATIONAHA.110.955369. PMID:20679547.
-
(2010)
Circulation
, vol.122
, Issue.7
, pp. 717-728
-
-
Zhong, J.1
Basu, R.2
Guo, D.3
Chow, F.L.4
Byrns, S.5
Schuster, M.6
-
92
-
-
78650170861
-
Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression
-
doi:10.1016/j.regpep.2010.09.005. PMID:20854846
-
Zhong, J.C., Ye, J.Y., Jin, H.Y., Yu, X., Yu, H.M., Zhu, D.L., et al. 2011. Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression. Regul. Pept. 166(1-3): 90-97. doi:10.1016/j.regpep.2010.09.005. PMID:20854846.
-
(2011)
Regul. Pept
, vol.166
, Issue.1-3
, pp. 90-97
-
-
Zhong, J.C.1
Ye, J.Y.2
Jin, H.Y.3
Yu, X.4
Yu, H.M.5
Zhu, D.L.6
|