Angiotensin-converting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways

Regulatory Peptides

Volumn 185, Issue , 2013, Pages 44-51

  Song, Bei ^a,b   Jin, Haiyan ^a   Yu, Xi ^c   Zhang, Zhenzhou ^a,b   Yu, Huimin ^d   Ye, Jing ^a   Xu, Yingle ^a,b   Zhou, Tong ^a   Oudit, Gavin Y ^e   Ye, Jia Ying ^c   Chen, Chen ^a   Gao, Pingjin ^a,b   Zhu, Dingliang ^a,b   Penninger, Josef M ^f   Zhong, Jiu Chang ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Institute of Hypertension   (China)

^c NINGBO UNIVERSITY   (China)

^d GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^e UNIVERSITY OF ALBERTA   (Canada)

^f ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Angiotensin II; Angiotensin converting enzyme 2; Cell proliferation; Oxidative stress; Profilin 1; Suppressor of cytokine signaling 3

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANGIOTENSIN CONVERTING ENZYME 2; DX 600; ENZYME INHIBITOR; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROFILIN; PROFILIN I; RECOMBINANT ANGIOTENSIN CONVERTING ENZYME 2; RECOMBINANT ENZYME; SMALL INTERFERING RNA; STAT3 PROTEIN; SUPEROXIDE; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; WP 1066;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UMBILICAL ARTERY; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME 2; CELL PROLIFERATION; OXIDATIVE STRESS; PROFILIN-1; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANGIOTENSIN II; CELL PROLIFERATION; CELLS, CULTURED; GENE EXPRESSION; HUMANS; JANUS KINASE 2; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PEPTIDYL-DIPEPTIDASE A; PROFILINS; RECEPTOR, ANGIOTENSIN, TYPE 1; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; UMBILICAL CORD;

EID: 84880584666     PISSN: 01670115     EISSN: 18731686     Source Type: Journal    
DOI: 10.1016/j.regpep.2013.06.007     Document Type: Article

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