In vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 3037-3047

  Baldi, Giovanni ^a   Ravagli, Costanza ^a   Mazzantini, Filippo ^a   Loudos, George ^b   Adan, Jaume ^c   Masa, Marc ^c   Psimadas, Dimitrios ^b   Fragogeorgi, Eirini A ^b   Locatelli, Erica ^d   Innocenti, Claudia ^e,f   Sangregorio, Claudio ^e,g   Franchini, Mauro Comes ^d  

^a CERICOL ^*  (Italy)

^b UNIVERSITY OF WEST ATTICA   (Greece)

^c LEITAT TECHNOLOGICAL CENTER   (Spain)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e Chemistry Department   (Italy)

^f UNIVERSITY OF FLORENCE   (Italy)

^g CNR   (Italy)

Author keywords

Hyperthermia; Imaging; Magnetic nanoparticles; Polymeric nanocarriers; Single photon emission computed tomography; Skin cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; MACROGOL; MAGNETIC NANOPARTICLE; NANOCARRIER; POLYGLACTIN; TECHNETIUM 99M; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; LACTIC ACID; MACROGOL DERIVATIVE; MAGNETITE NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TECHNETIUM;

A431 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARCINOMA CELL; CLINICAL EFFECTIVENESS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HYBRIDOMA; HYPERTHERMIC THERAPY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SQUAMOUS CELL CARCINOMA; TEMPERATURE; TUMOR CELL LINE; TUMOR VOLUME; ANIMAL; CHEMISTRY; DRUG SCREENING; PROCEDURES; SCID MOUSE; TISSUE DISTRIBUTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; FEMALE; HUMANS; HYPERTHERMIA, INDUCED; LACTIC ACID; MAGNETITE NANOPARTICLES; MICE; MICE, SCID; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; RECEPTOR, EPIDERMAL GROWTH FACTOR; TECHNETIUM; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903291510     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S61273     Document Type: Article

References (59)

1. Schmidt G, editor. Nanoparticles. From Theory to Application. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA; 2004.
2. Feldheim DL, Foss CA. Metal Nanoparticles. Synthesis, Characterisation, and Application. New York, NY, USA: Dekker; 2002.
3. Vollath D, editor. Nanomaterials. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA; 2008.
4. Cademartiri L, Ozin GA. In: Lehn JM, editor. Concepts of Nanochemistry. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA; 2009.
5. Gao I. Biofunctionalization of nanomaterials. In: Challa SS, Kumar R, editors. Nanotechnologies for the Life Sciences. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA; 2006.
6. Hayashi K, Nakamura M, Sakamoto W, et al. Superparamagnetic nanoparticle clusters for cancer theranostics combining magnetic resonance imaging and hyperthermia treatment. Theranostics. 2013;3:366-376.
7. Lartigue L, Hugounenq P, Alloyeau D, et al. Cooperative organization in iron oxide multi-core nanoparticles potentiates their efficiency as heating mediators and MRI contrast agents. ACS Nano. 2012;6:10935-10949.
8. Thomas LA, Dekker L, Kallumadil M, et al. Carboxylic acid-stabilised iron oxide nanoparticles for use in magnetic hyperthermia. J Mater Chem. 2009;19:6529-6535.
9. Kaddi CD, Phan JH, Wang MD. Computational nanomedicine: modeling of nanoparticle-mediated hyperthermal cancer therapy. Nanomedicine. 2013;8:1323-1333.
10. Dürr S, Janko C, Lyer S, et al. Magnetic nanoparticles for cancer therapy. Nanotechnology Reviews. 2013;2:395-409.
11. Kumar CS, Mohammad F. Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. Adv Drug Deliv Rev. 2011;63:789-808.
12. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol. 2007;2:751-759.
13. Huang Y, He S, Cao W, Cai K, Liang XJ. Biomedical nanomaterials for imaging-guided cancer therapy. Nanoscale. 2012;4:6135-6149.
14. Chen H, Li S, Li B, et al. Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy. Nanoscale. 2012;4:6050-6064.
15. Yang J, Lee CH, Ko HJ. Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer. Angew Chem Int Ed. 2007;46:8836-8839.
16. Ahmed N, Fessi H, Elaissari A. Nanoparticles for cancer from diagnosis to theranostics. Drug Deliv Today. 2012;17:928-934.
17. Thiesen B, Jordan A. Clinical applications of magnetic nanoparticles for hyperthermia. Int J Hyperthermia. 2008;24:467-474.
18. Maier-Hauff K, Ulrich F, Nestler D, et al. Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy in patients with recurrent glioblastomamultiforme. J Neurooncol. 2011;103:317-324.
19. 3 synthesized by a single step process. J Mater Chem. 2007;17:5042-5051.
20. Jung JT, Nah H, Lee JH, Moon SH, Kim MG, Cheon J. Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles. Angew Chem Int Ed. 2009;48:1234-1238.
21. Lee JH, Jong JT, Choi JS, et al. Exchange-coupled magnetic nanoparticles for efficient heat induction. Nat Nanotechnol. 2011;6:418-422.
22. Yoo D, Jeong H, Preihs C, et al. Double-effector nanoparticles: a synergistic approach to apoptotic hyperthermia. Angew Chem Int Ed Engl. 2012;51:12482-12485.
23. Ito A, Kuga Y, Honda H, et al. Magnetite nanoparticle-loaded anti-HER2 immunoliposomes for combination of antibody therapy with hyperthermia. Cancer Lett. 2004;212:167-175.
24. Macková H, Horák D, Trachtová Š, Rittich B, Španová A. The use of magnetic poly(N-isopropylacrylamide) microspheres for separation of DNA from probiotic dairy products. Journal of Colloid Science and Biotechnology. 2012;1:235-240.
25. Rahman MM, Elaissari A. Multi-stimuli responsive magnetic core-shell particles: synthesis, characterization and specific RNA recognition. Journal of Colloid Science and Biotechnology. 2012;1:3-15.
26. Medeiros SF, Santos AM, Fessi H, Elaissari A. Thermally-sensitive and magnetic poly(n-vinylcaprolactam)-based nanogels by inverse miniemulsion polymerization. Journal of Colloid Science and Biotechnology. 2012;1:99-112.
27. Shen JM, Yin T, Tian XZ, Gao FY, Xu S. Surface charge-switchable polymeric magnetic nanoparticles for the controlled release of anticancer drug. ACS Appl Mater Interfaces. 2013;5:7014-7024.
28. Shen JM, Gao FY, Yin T, et al. cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy. Pharmacol Res. 2013;70:102-115.
29. Shen JM, Guan XM, Liu XY, Lan JF, Cheng T, Zhang HX. Luminescent/magnetic hybrid nanoparticles with folate-conjugated peptide composites for tumor-targeted drug delivery. Bioconjug Chem. 2012;23:1010-1021.
30. Machulla HJ, Uludag K, Cherry SR, et al. Simultaneous PET-MRI: a new approach for functional and morphological imaging. Nat Med. 2008;14:459-465.
31. Meier D, Wagenaar DJ, Chen S, Xu J, Yu J, Tsui BM. A SPECT camera for combined MRI and SPECT for small animals. Nucl Instrum Methods Phys Res A. 2011;652:731-734.
32. Bouziotis P, Psimadas D, Tsotakos T, Stamopoulos D, Tsoukalas C. Radiolabeled iron oxide nanoparticles as dual-modality SPECT/MRI and PET/MRI agents. Curr Top Med Chem. 2012;12:2694-2702.
33. Comes Franchini M, Baldi G, Bonacchi D, et al. Bovine serum albumin-based magnetic nanocarrier for MRI diagnosis and hyperthermic therapy: a potential theranostic approach against cancer. Small. 2010;6:366-370.
34. Misri R, Meier D, Yung AC, Kozlowski P, Häfeli UO. Development and evaluation of a dual-modality (MRI/SPECT) molecular imaging bioprobe. Nanomedicine. 2012;8:1007-1016.
35. Knop K, Hoogenboom R, Fischer D, Schubert US. Poly(ethylene glycol) in drug delivery: pros and cons as well as potential alternatives. Chem Rev. 2010;49:6288-6308.
36. Loudos G, Majewski S, Wojcik R, Varvarigou A. Performance evaluation of a dedicated camera suitable for dynamic radiopharmaceuticals evaluation in small animals. IEEE Trans Nucl Sci. 2007:54:3-9.
37. Juarranz A, Jaén P, Sanz-Rodríguez F, Cuevas J, González S. Photodynamic therapy of cancer. Basic principles and applications. Clin Transl Oncol. 2008;10:148-154.
38. Baldi G, Bonacchi D, Innocenti C, et al. Cobalt-ferrite nanoparticles: the control of the average size and surface state and their effects on magnetic properties. J Magn Magn Mater. 2007;311:10-16.
39. Hunt CP, Moskowitz BM, Banerjee SK. Magnetic properties of rocks and minerals. In: Ahrens TJ, editor. Rock Physics and Phase Relations: A Handbook of Physical Constants. Washington, DC, USA: American Geophysical Union; 1995.
40. Ai H, Flask C, Weinberg B, et al. Magnetite-loaded polymeric micelles as ultrasensitive magnetic-resonance probes. Adv Mater. 2005;17:1949-1952.
41. Baldi G, Bonacchi D, Innocenti F. PCT Int. Appl. 2008, 71pp. CODEN: PIXXD2 WO 2008074804 A2 20080626.
42. Baldi G, Bonacchi D, Comes Franchini M, et al. Synthesis and coating of cobalt ferrite nanoparticles: a first step toward the obtainment of new magnetic nanocarriers. Langmuir. 2007;7:4026-4028.
43. 4 (M = Fe, Co, Mn) nanoparticles. J Am Chem Soc. 2004;126:273-279.
44. Gref R, Minamitake Y, Peracchia MT, Trubetskoy V, Torchilin V, Langer R. Biodegradable long-circulating polymeric nanospheres. Science. 1994;263:1600-1603.
45. Hergt R, Hiergeist RR, Zeisberger M, et al. Enhancement of AC-losses of magnetic nanoparticles for heating applications. J Magn Magn Mater. 2004;280:358-368.
46. Psimadas D, Baldi G, Ravagli C, et al. Preliminary evaluation of a 99mTc labeled hybrid nanoparticle bearing a cobalt ferrite core: in vivo biodistribution. J Biomed Nanotechnol. 2012;8:575-585.
47. 4 metal cores. Nanotechnology. 2014;25:25101-25110.
48. 2.
49. Comes Franchini M, Bonini BF, Camaggi CM, et al. Design and synthesis of novel pyrazoles for nanomedicine applications against malignant gliomas. Eur J Med Chem. 2010;45:2024-2033.
50. Locatelli E, Comes Franchini M. Biodegradable PLGA-b-PEG polymeric nanoparticles: synthesis, properties, and nanomedical applications as drug delivery system. J Nanopart Res. 2012;14:1316-1324.
51. Gu F, Zhang L, Teply BA, et al. Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci U S A. 2008;105:2586-2595.
52. Hergt R, Dutz S. Magnetic particle hyperthermia-biophysical limitations of a visionary tumour therapy. J Magn Magn Mater. 2007;311:187-192.
53. Derfus AM, Maltzahn GV, Harris TJ, et al. Remotely triggered release from magnetic nanoparticles. Adv Mater. 2007;19:3932-3936.
54. Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol. 2001;2:127-137.
55. Bleeker WK, Lammerts van Bueren JJ, van Ojik HH, et al. Dual mode of action of a human anti-epidermal growth factor receptor monoclonal antibody for cancer therapy. J Immunol. 2004;173:4699-4707.
56. Zhao Q, Wang L, Cheng R, et al. Magnetic nanoparticle-based hyperthermia for head and neck cancer in mouse models. Theranostics. 2012;2:113-121.
57. Jordan A, Scholz R, Maier-Hauff K, et al. The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma. J Neurooncol. 2006;78:7-14.
58. Elsherbini AA, Saber M, Aggag M, El-Shahawy A, Shokier HA. Magnetic nanoparticle-induced hyperthermia treatment under magnetic resonance imaging. Magn Reson Imaging. 2011;29:272-280.
59. Tanaka K, Ito A, Kobayashi K, et al. Intratumoral injection of immature dendritic cells enhances antitumor effect of hyperthermia using magnetic nanoparticles. Int J Cancer. 2005;116:624-633.