TCA cycle-mediated generation of ROS is a key mediator for HeR-MRSA survival under β-lactam antibiotic exposure

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Rosato, Roberto R ^a   Fernandez, Regina ^a   Paz, Liliana I ^a   Singh, Christopher R ^a   Rosato, Adriana E ^a,b  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; CITRIC ACID; REACTIVE OXYGEN METABOLITE; 2,2' BIPYRIDINE; ANTIINFECTIVE AGENT; BACTERIAL DNA; BACTERIAL PROTEIN; BETA LACTAM; MECA PROTEIN, STAPHYLOCOCCUS AUREUS; OXACILLIN; PENICILLIN BINDING PROTEIN; THIOUREA;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL WALL; BACTERIAL METABOLISM; BACTERIAL MUTATION; BACTERIAL STRAIN; BACTERIAL SURVIVAL; CITRIC ACID CYCLE; CONTROLLED STUDY; DNA DAMAGE; DRUG EXPOSURE; ENERGY RESOURCE; HETERO RESISTANT METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; HOMO RESISTANT METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MUTAGENESIS; MUTATION RATE; NONHUMAN; ADAPTATION; DNA REPAIR; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MULTIDRUG RESISTANCE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

2,2'-DIPYRIDYL; ADAPTATION, PHYSIOLOGICAL; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMS; CITRIC ACID CYCLE; DNA DAMAGE; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENE EXPRESSION PROFILING; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MUTATION RATE; OXACILLIN; PENICILLIN-BINDING PROTEINS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; SOS RESPONSE (GENETICS); THIOUREA;

EID: 84903287334     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099605     Document Type: Article

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