Targeting of PBP1 by β-lactams Determines recA/SOS Response Activation in Heterogeneous MRSA Clinical Strains

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Plata, Konrad B ^a,b   Riosa, Sarah ^a,b   Singh, Christopher R ^a,b   Rosato, Roberto R ^a,b   Rosato, Adriana E ^a,b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACITRACIN; BETA LACTAM ANTIBIOTIC; CEFACLOR; CEFOTAXIME; CEFOXITIN; CEFTOBIPROLE; CLOXACILLIN; CYCLOSERINE; DRUG BINDING PROTEIN; IMIPENEM; OXACILLIN; PENICILLIN BINDING PROTEIN 1; PENICILLIN BINDING PROTEIN 2; PENICILLIN BINDING PROTEIN 2A; PENICILLIN BINDING PROTEIN 4; RECA PROTEIN; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; BACTERIAL DNA; BACTERIAL PROTEIN; BETA LACTAM;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CELL HETEROGENEITY; CONTROLLED STUDY; DNA REPAIR; DRUG EFFICACY; DRUG EXPOSURE; GENETIC SELECTION; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MINIMUM INHIBITORY CONCENTRATION; MUTATION RATE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LEPIDOPTERA; METABOLISM; MICROBIOLOGY;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; LEPIDOPTERA; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; OXACILLIN; SOS RESPONSE (GENETICS);

EID: 84876524188     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061083     Document Type: Article

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