Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome

Cellular and Molecular Life Sciences

Volumn 71, Issue 14, 2014, Pages 2625-2639

  Bharti, Sanjay Kumar ^a   Khan, Irfan ^a   Banerjee, Taraswi ^a   Sommers, Joshua A ^a   Wu, Yuliang ^b   Brosh, Robert M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

ChlR1; Cohesinopathy; DDX11; Genetic disease; Genomic instability; Helicase; Warsaw breakage syndrome

Indexed keywords

CAMPTOTHECIN; CHLR1 PROTEIN; DNA HELICASE; GLYCOPROTEIN E1; MITOMYCIN; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG; VIRUS PROTEIN;

CAENORHABDITIS ELEGANS; CELL SURVIVAL; CHLR1 GENE; CHROMATID ABERRATION; CHROMATIN STRUCTURE; CHROMOSOMAL INSTABILITY; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CLINICAL FEATURE; CONGENITAL DISORDER; DNA DAMAGE; DNA PROTEIN COMPLEX; DNA REPAIR; DNA REPLICATION; DNA STRUCTURE; ENZYME DEFICIENCY; FANCONI ANEMIA; GENE; GENE FUNCTION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC TRANSFECTION; GROWTH RETARDATION; HETEROCHROMATIN; HOMOLOGOUS RECOMBINATION; MELANOMA CELL; MICROCEPHALY; MUS MUSCULUS; NONHUMAN; PAPILLOMA VIRUS; PHENOTYPE; PIGMENT DISORDER; PROTEIN INTERACTION; REVIEW; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SISTER CHROMATID; SISTER CHROMATID COHESION DEFECT; VIRUS GENOME; WARSAW BREAKAGE SYNDROME;

PAPILLOMAVIRIDAE; SACCHAROMYCETALES;

ABNORMALITIES, MULTIPLE; DEAD-BOX RNA HELICASES; DNA BREAKS; DNA HELICASES; G-QUADRUPLEXES; GENOMIC INSTABILITY; HOMEOSTASIS; HUMANS; MITOMYCIN; MUTATION; NEOPLASMS; PAPILLOMAVIRIDAE; PHENOTYPE; SUBSTRATE SPECIFICITY; SYNDROME;

EID: 84903277943     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1569-4     Document Type: Review

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