Hypoxia-Inducible Factor-2α Is an Essential Catabolic Regulator of Inflammatory Rheumatoid Arthritis

PLoS Biology

Volumn 12, Issue 6, 2014, Pages 1-16

  Ryu, Je Hwang ^a,b   Chae, Chang Suk ^a   Kwak, Ji Sun ^a   Oh, Hwanhee ^a   Shin, Youngnim ^a   Huh, Yun Hyun ^a   Lee, Choong Gu ^a   Park, Yong Wook ^c   Chun, Churl Hong ^d   Kim, Young Myeong ^e   Im, Sin Hyeog ^f   Chun, Jang Soo ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Chonnam National University   (South Korea)

^c Chonnam National University Medical School   (South Korea)

^d Wonkwang University School of Medicine   (South Korea)

^e Kangwon National University   (South Korea)

^f Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; PANNUS; PATHOGENESIS; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM; TH17 CELL; UPREGULATION; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; C57BL MOUSE; CELL DIFFERENTIATION; CYTOLOGY; DBA MOUSE; IMMUNOLOGY; METABOLISM; PHENOTYPE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-6; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; PHENOTYPE; SYNOVIAL MEMBRANE; TH17 CELLS; UP-REGULATION;

EID: 84903271736     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001881     Document Type: Article

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