CD147 induces angiogenesis through a vascular endothelial growth factor and hypoxia-inducible transcription factor 1α-mediated pathway in rheumatoid arthritis

Arthritis and Rheumatism

Volumn 64, Issue 6, 2012, Pages 1818-1827

  Wang, Cong Hua ^a   Yao, Hui ^a   Chen, Li Na ^a   Jia, Jun Feng ^a   Wang, Li ^a   Dai, Jing Yao ^a   Zheng, Zhao Hui ^a   Chen, Zhi Nan ^a   Zhu, Ping ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INFLIXIMAB; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD147; ANTIGENS, CD31; ARTHRITIS, RHEUMATOID; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; OSTEOARTHRITIS, KNEE; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84861815451     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34341     Document Type: Article

References (22)

1. Firestein GS,. Evolving concepts of rheumatoid arthritis. Nature 2003; 423: 356-61.
2. Koch AE,. Angiogenesis: implications for rheumatoid arthritis [review]. Arthritis Rheum 1998; 41: 951-62.
3. 2! See what HIF can do! Ann Rheum Dis 2005; 64: 971-80.
4. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24.
5. Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL,. Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38: 44-8.
6. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. Arthritis Rheum 2000; 43: 1905-15.
7. Zhu P, Lu N, Shi ZG, Zhou J, Wu ZB, Yang Y, et al. CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes. Arthritis Res Ther 2006; 8: R44.
8. Jiang JL, Zhou Q, Yu MK, Ho LS, Chen ZN, Chan HC,. The involvement of HAb18G/CD147 in regulation of store-operated calcium entry and metastasis of human hepatoma cells. J Biol Chem 2001; 276: 46870-7.
9. Lories RJ, Derese I, Ceuppens JL, Luyten FP,. Bone morphogenetic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. Arthritis Rheum 2003; 48: 2807-18.
10. Geiler T, Kriegsmann J, Keyszer GM, Gay RE, Gay S,. A new model for rheumatoid arthritis generated by engraftment of rheumatoid synovial tissue and normal human cartilage into SCID mice. Arthritis Rheum 1994; 37: 1664-71.
11. Jia J, Wang C, Shi Z, Zhao J, Jia Y, Zhao-Hui Z, et al. Inhibitory effect of CD147/HAb18 monoclonal antibody on cartilage erosion and synovitis in the SCID mouse model for rheumatoid arthritis. Rheumatology (Oxford) 2009; 48: 721-6.
12. Nagashima M, Yoshino S, Ishiwata T, Asano G,. Role of vascular endothelial growth factor in angiogenesis of rheumatoid arthritis. J Rheumatol 1995; 22: 1624-30.
13. Giatromanolaki A, Sivridis E, Athanassou N, Zois E, Thorpe PE, Brekken RA, et al. The angiogenic pathway "vascular endothelial growth factor/flk-1(KDR)-receptor" in rheumatoid arthritis and osteoarthritis. J Pathol 2001; 194: 101-8.
14. Del Rey MJ, Izquierdo E, Caja S, Usategui A, Santiago B, Galindo M, et al. Human inflammatory synovial fibroblasts induce enhanced myeloid cell recruitment and angiogenesis through a hypoxia-inducible transcription factor 1α/vascular endothelial growth factor-mediated pathway in immunodeficient mice. Arthritis Rheum 2009; 60: 2926-34.
15. Zhu P, Ding J, Zhou J, Dong WJ, Fan CM, Chen ZN,. Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production. Arthritis Res Ther 2005; 7: R1023-33.
16. Feldmann M, Maini RN,. Anti-TNFα therapy of rheumatoid arthritis: what have we learned? Annu Rev Immunol 2001; 19: 163-96.
17. Paleolog EM, Young S, Stark AC, McCloskey RV, Feldmann M, Maini RN,. Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor α and interleukin-1 in rheumatoid arthritis. Arthritis Rheum 1998; 41: 1258-65.
18. Hashizume M, Hayakawa N, Suzuki M, Mihara M,. IL-6/sIL-6R trans-signalling, but not TNF-α induced angiogenesis in a HUVEC and synovial cell co-culture system. Rheumatol Int 2009; 29: 1449-54.
19. Zhou J, Schmid T, Brune B,. Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-κB-dependent pathway. Mol Biol Cell 2003; 14: 2216-25.
20. Sun J, Hemler ME,. Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions. Cancer Res 2001; 61: 2276-81.
21. Li HM, Zhu P, Fan CM, Wang YH, Zheng ZH, Li XY, et al. Effects of PMA on CD147 expression in cultured THP-1 cells and monocytes of RA patients. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006; 22: 333-5, 338. In Chinese.
22. Damsker JM, Okwumabua I, Pushkarsky T, Arora K, Bukrinsky MI, Constant SL,. Targeting the chemotactic function of CD147 reduces collagen-induced arthritis. Immunology 2009; 126: 55-62.