Direct activation of ATM by resveratrol under oxidizing conditions

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Lee, Ji Hoon ^a   Guo, Zhi ^b,c   Myler, Logan R ^a   Zheng, Suting ^a   Paull, Tanya T ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BLEOMYCIN; GENISTEIN; HYDROGEN PEROXIDE; PICEATANNOL; REACTIVE OXYGEN METABOLITE; RESVERATROL; ANTIOXIDANT; ATM PROTEIN, HUMAN; OXIDIZING AGENT; STILBENE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHOSPHORYLATION; CELL TRANSFORMATION; CONTROLLED STUDY; DISULFIDE BOND; DNA DAMAGE; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; OXIDATION; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; CELL LINE; CELL PROLIFERATION; DRUG EFFECTS; HCT116 CELL LINE; HEK293 CELL LINE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BLEOMYCIN; CELL LINE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; HCT116 CELLS; HEK293 CELLS; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STILBENES;

EID: 84903220507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097969     Document Type: Article

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