Screening for inhibition of Vibrio cholerae VipA-VipB interaction identifies small-molecule compounds active against type VI secretion

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 7, 2014, Pages 4123-4130

  Sun, Kun ^a   Brom̈s, Jeanette ^a   Lavander, Moa ^a,b   Gurram, Bharat Kumar ^a   Enquist, Per Anders ^a   Andersson, C David ^a   Elofsson, Mikael ^a   Sjos̈tedt, Anders ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b National Food Agency   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; HEMOLYSIN COREGULATED PROTEIN; KS 100; KS 200; LACTATE DEHYDROGENASE; PHOSPHOLIPASE A1; PROTEIN VIPA; PROTEIN VIPB; UNCLASSIFIED DRUG; BACTERIAL SECRETION SYSTEM; HCP PROTEIN, VIBRIO CHOLERAE; HEMOLYSIN; VIRULENCE FACTOR;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; CACO 2 CELL LINE; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVITY; EUKARYOTIC CELL; GROWTH INHIBITION; HIGH THROUGHPUT SCREENING; MDCK CELL LINE; MEMBRANE PERMEABILITY; MOLECULAR LIBRARY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; STRUCTURE ACTIVITY RELATION; TWO HYBRID SYSTEM; TYPE VI SECRETION SYSTEM; VIBRIO CHOLERAE; ANTAGONISTS AND INHIBITORS; BACTERIAL SECRETION SYSTEM; DRUG EFFECTS; METABOLISM; MICROBIAL SENSITIVITY TEST; MOLECULAR GENETICS; PATHOGENICITY; SECRETION (PROCESS);

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; HEMOLYSIN PROTEINS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A1; VIBRIO CHOLERAE; VIRULENCE FACTORS;

EID: 84903202590     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02819-13     Document Type: Article

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