-
1
-
-
35048833315
-
Mutations in the ubiquitin binding UBZ motif of DNA polymerase η do not impair its function in translesion synthesis during replication
-
Acharya, N., Brahma, A., Haracska, L., Prakash, L. & Prakash, S. (2007) Mutations in the ubiquitin binding UBZ motif of DNA polymerase η do not impair its function in translesion synthesis during replication. Mol. Cell. Biol. 27, 7266-7272.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7266-7272
-
-
Acharya, N.1
Brahma, A.2
Haracska, L.3
Prakash, L.4
Prakash, S.5
-
2
-
-
56649124781
-
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase η in translesion DNA synthesis
-
Acharya, N., Yoon, J.-H., Gali, H., Unk, I., Haracska, L., Johnson, R.E., Hurwitz, J., Prakash, L. & Prakash, S. (2008) Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase η in translesion DNA synthesis. Proc. Natl Acad. Sci. USA 105, 17724-17729.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 17724-17729
-
-
Acharya, N.1
Yoon, J.-H.2
Gali, H.3
Unk, I.4
Haracska, L.5
Johnson, R.E.6
Hurwitz, J.7
Prakash, L.8
Prakash, S.9
-
3
-
-
77953751029
-
DNA polymerase η lacking the ubiquitin-binding domain promotes replicative lesion bypass in human cells
-
Acharya, N., Yoon, J.-H., Hurwitz, J., Prakash, L. & Prakash, S. (2010) DNA polymerase η lacking the ubiquitin-binding domain promotes replicative lesion bypass in human cells. Proc. Natl Acad. Sci. USA 107, 10401-10405.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10401-10405
-
-
Acharya, N.1
Yoon, J.-H.2
Hurwitz, J.3
Prakash, L.4
Prakash, S.5
-
4
-
-
77953924511
-
Structure and mechanism of human DNA polymerase η
-
Biertumpfel, C., Zhao, Y., Kondo, Y., Ramón-Maiques, S., Gregory, M., Lee, J.Y., Masutani, C., Lehmann, A.R., Hanaoka, F. & Yang, W. (2010) Structure and mechanism of human DNA polymerase η. Nature 465, 1044-1048.
-
(2010)
Nature
, vol.465
, pp. 1044-1048
-
-
Biertumpfel, C.1
Zhao, Y.2
Kondo, Y.3
Ramón-Maiques, S.4
Gregory, M.5
Lee, J.Y.6
Masutani, C.7
Lehmann, A.R.8
Hanaoka, F.9
Yang, W.10
-
5
-
-
0037020269
-
Human DNA polymerase κ bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides
-
Fischhaber, P.L., Gerlach, V.L., Feaver, W.J., Hatahet, Z., Wallace, S.S. & Friedberg, E.C. (2002) Human DNA polymerase κ bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. J. Biol. Chem. 277, 37604-37611.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37604-37611
-
-
Fischhaber, P.L.1
Gerlach, V.L.2
Feaver, W.J.3
Hatahet, Z.4
Wallace, S.S.5
Friedberg, E.C.6
-
6
-
-
12844271626
-
A single domain in human DNA polymerase ι mediates interaction with PCNA: implications for translesion DNA synthesis
-
Haracska, L., Acharya, N., Unk, I., Johnson, R.E., Hurwitz, J., Prakash, L. & Prakash, S. (2005) A single domain in human DNA polymerase ι mediates interaction with PCNA: implications for translesion DNA synthesis. Mol. Cell. Biol. 25, 1183-1190.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1183-1190
-
-
Haracska, L.1
Acharya, N.2
Unk, I.3
Johnson, R.E.4
Hurwitz, J.5
Prakash, L.6
Prakash, S.7
-
7
-
-
0034785579
-
Physical and functional interactions of human DNA polymerase η with PCNA
-
Haracska, L., Johnson, R.E., Unk, I., Phillips, B.B., Hurwitz, J., Prakash, L. & Prakash, S. (2001a) Physical and functional interactions of human DNA polymerase η with PCNA. Mol. Cell. Biol. 21, 7199-7206.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7199-7206
-
-
Haracska, L.1
Johnson, R.E.2
Unk, I.3
Phillips, B.B.4
Hurwitz, J.5
Prakash, L.6
Prakash, S.7
-
8
-
-
0035807870
-
Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA
-
Haracska, L., Johnson, R.E., Unk, I., Phillips, B.B., Hurwitz, J., Prakash, L. & Prakash, S. (2001b) Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA. Proc. Natl Acad. Sci. USA 98, 14256-14261.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14256-14261
-
-
Haracska, L.1
Johnson, R.E.2
Unk, I.3
Phillips, B.B.4
Hurwitz, J.5
Prakash, L.6
Prakash, S.7
-
9
-
-
0034852569
-
Interaction with PCNA is essential for yeast DNA polymerase η function
-
Haracska, L., Kondratick, C.M., Unk, I., Prakash, S. & Prakash, L. (2001c) Interaction with PCNA is essential for yeast DNA polymerase η function. Mol. Cell 8, 407-415.
-
(2001)
Mol. Cell
, vol.8
, pp. 407-415
-
-
Haracska, L.1
Kondratick, C.M.2
Unk, I.3
Prakash, S.4
Prakash, L.5
-
10
-
-
2942529467
-
Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae
-
Haracska, L., Torres-Ramos, C.A., Johnson, R.E., Prakash, S. & Prakash, L. (2004) Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol. Cell. Biol. 24, 4267-4274.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4267-4274
-
-
Haracska, L.1
Torres-Ramos, C.A.2
Johnson, R.E.3
Prakash, S.4
Prakash, L.5
-
11
-
-
0036140598
-
Stimulation of DNA synthesis activity of human DNA polymerase κ by PCNA
-
Haracska, L., Unk, I., Johnson, R.E., Phillips, B.B., Hurwitz, J., Prakash, L. & Prakash, S. (2002) Stimulation of DNA synthesis activity of human DNA polymerase κ by PCNA. Mol. Cell. Biol. 22, 784-791.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 784-791
-
-
Haracska, L.1
Unk, I.2
Johnson, R.E.3
Phillips, B.B.4
Hurwitz, J.5
Prakash, L.6
Prakash, S.7
-
12
-
-
33646254420
-
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis
-
Haracska, L., Unk, I., Prakash, L. & Prakash, S. (2006) Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Proc. Natl Acad. Sci. USA 103, 6477-6482.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 6477-6482
-
-
Haracska, L.1
Unk, I.2
Prakash, L.3
Prakash, S.4
-
13
-
-
67449103688
-
Structural basis for novel interactions between human translesion synthesis polymerases and proliferating cell nuclear antigen
-
Hishiki, A., Hashimoto, H., Hanafusa, T., Kamei, K., Ohashi, E., Shimizu, T., Ohmori, H. & Sato, M. (2009) Structural basis for novel interactions between human translesion synthesis polymerases and proliferating cell nuclear antigen. J. Biol. Chem. 284, 10552-10560.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 10552-10560
-
-
Hishiki, A.1
Hashimoto, H.2
Hanafusa, T.3
Kamei, K.4
Ohashi, E.5
Shimizu, T.6
Ohmori, H.7
Sato, M.8
-
14
-
-
0037068455
-
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
-
Hoege, C., Pfander, B., Moldovan, G.-L., Pyrowolakis, G. & Jentsch, S. (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419, 135-141.
-
(2002)
Nature
, vol.419
, pp. 135-141
-
-
Hoege, C.1
Pfander, B.2
Moldovan, G.-L.3
Pyrowolakis, G.4
Jentsch, S.5
-
15
-
-
0033538470
-
hRAD30 mutations in the variant form of xeroderma pigmentosum
-
Johnson, R.E., Kondratick, C.M., Prakash, S. & Prakash, L. (1999a) hRAD30 mutations in the variant form of xeroderma pigmentosum. Science 285, 263-265.
-
(1999)
Science
, vol.285
, pp. 263-265
-
-
Johnson, R.E.1
Kondratick, C.M.2
Prakash, S.3
Prakash, L.4
-
16
-
-
33745219847
-
Yeast and human translesion DNA synthesis polymerases: expression, purification, and biochemical characterization
-
Johnson, R.E., Prakash, L. & Prakash, S. (2006) Yeast and human translesion DNA synthesis polymerases: expression, purification, and biochemical characterization. Methods Enzymol. 408, 390-407.
-
(2006)
Methods Enzymol.
, vol.408
, pp. 390-407
-
-
Johnson, R.E.1
Prakash, L.2
Prakash, S.3
-
17
-
-
0033548231
-
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη
-
Johnson, R.E., Prakash, S. & Prakash, L. (1999b) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη. Science 283, 1001-1004.
-
(1999)
Science
, vol.283
, pp. 1001-1004
-
-
Johnson, R.E.1
Prakash, S.2
Prakash, L.3
-
18
-
-
33847208855
-
Human DNA polymerase κ encircles DNA: implications for mismatch extension and lesion bypass
-
Lone, S., Townson, S.A., Uljon, S.N., Johnson, R.E., Brahma, A., Nair, D.T., Prakash, S., Prakash, L. & Aggarwal, A.K. (2007) Human DNA polymerase κ encircles DNA: implications for mismatch extension and lesion bypass. Mol. Cell 25, 601-614.
-
(2007)
Mol. Cell
, vol.25
, pp. 601-614
-
-
Lone, S.1
Townson, S.A.2
Uljon, S.N.3
Johnson, R.E.4
Brahma, A.5
Nair, D.T.6
Prakash, S.7
Prakash, L.8
Aggarwal, A.K.9
-
19
-
-
0033578040
-
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η
-
Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S., Takio, K. & Hanaoka, F. (1999) The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature 399, 700-704.
-
(1999)
Nature
, vol.399
, pp. 700-704
-
-
Masutani, C.1
Kusumoto, R.2
Yamada, A.3
Dohmae, N.4
Yokoi, M.5
Yuasa, M.6
Araki, M.7
Iwai, S.8
Takio, K.9
Hanaoka, F.10
-
20
-
-
26444528004
-
Human DNA polymerase ι incorporates dCTP opposite template G via a G.C+ Hoogsteen base pair
-
Nair, D.T., Johnson, R.E., Prakash, L., Prakash, S. & Aggarwal, A.K. (2005a) Human DNA polymerase ι incorporates dCTP opposite template G via a G.C+ Hoogsteen base pair. Structure 13, 1569-1577.
-
(2005)
Structure
, vol.13
, pp. 1569-1577
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
21
-
-
25844440534
-
Rev1 employs a novel mechanism of DNA synthesis using a protein template
-
Nair, D.T., Johnson, R.E., Prakash, L., Prakash, S. & Aggarwal, A.K. (2005b) Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science 309, 2219-2222.
-
(2005)
Science
, vol.309
, pp. 2219-2222
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
22
-
-
33745808012
-
Hoogsteen base pair formation promotes synthesis opposite the 1, N6-ethenodeoxyadenosine lesion by human DNA polymerase iota
-
Nair, D.T., Johnson, R.E., Prakash, L., Prakash, S. & Aggarwal, A.K. (2006a) Hoogsteen base pair formation promotes synthesis opposite the 1, N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat. Struct. Mol. Biol. 13, 619-625.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 619-625
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
23
-
-
3142674288
-
Replication by human DNA polymerase ι occurs via Hoogsteen base-pairing
-
Nair, D.T., Johnson, R.E., Prakash, S., Prakash, L. & Aggarwal, A.K. (2004) Replication by human DNA polymerase ι occurs via Hoogsteen base-pairing. Nature 430, 377-380.
-
(2004)
Nature
, vol.430
, pp. 377-380
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, S.3
Prakash, L.4
Aggarwal, A.K.5
-
24
-
-
33646492746
-
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-ι active site
-
Nair, D.T., Johnson, R.E., Prakash, S., Prakash, L. & Aggarwal, A.K. (2006b) An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-ι active site. Structure 14, 749-755.
-
(2006)
Structure
, vol.14
, pp. 749-755
-
-
Nair, D.T.1
Johnson, R.E.2
Prakash, S.3
Prakash, L.4
Aggarwal, A.K.5
-
25
-
-
77953921670
-
Structural basis for the suppression of skin cancers by DNA polymerase eta
-
Silverstein, T.D., Johnson, R.E., Jain, R., Prakash, L., Prakash, S. & Aggarwal, A.K. (2010) Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature 465, 1039-1043.
-
(2010)
Nature
, vol.465
, pp. 1039-1043
-
-
Silverstein, T.D.1
Johnson, R.E.2
Jain, R.3
Prakash, L.4
Prakash, S.5
Aggarwal, A.K.6
-
26
-
-
0141831006
-
Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation
-
Stelter, P. & Ulrich, H.D. (2003) Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 425, 188-191.
-
(2003)
Nature
, vol.425
, pp. 188-191
-
-
Stelter, P.1
Ulrich, H.D.2
-
27
-
-
67649381629
-
Structure of the human REV1-DNA-dNTP ternary complex
-
Swan, M.K., Johnson, R.E., Prakash, L., Prakash, S. & Aggarwal, A.K. (2009) Structure of the human REV1-DNA-dNTP ternary complex. J. Mol. Biol. 390, 699-709.
-
(2009)
J. Mol. Biol.
, vol.390
, pp. 699-709
-
-
Swan, M.K.1
Johnson, R.E.2
Prakash, L.3
Prakash, S.4
Aggarwal, A.K.5
-
28
-
-
9144258471
-
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase ι
-
Vidal, A.E., Kannouche, P., Podust, V.N., Yang, W., Lehmann, A.R. & Woodgate, R. (2004) Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase ι. J. Biol. Chem. 279, 48360-48368.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 48360-48368
-
-
Vidal, A.E.1
Kannouche, P.2
Podust, V.N.3
Yang, W.4
Lehmann, A.R.5
Woodgate, R.6
-
29
-
-
77956289981
-
Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases κ and ζ in human cells
-
Yoon, J.-H., Bhatia, G., Prakash, S. & Prakash, L. (2010) Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases κ and ζ in human cells. Proc. Natl Acad. Sci. USA 107, 14116-14122.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14116-14122
-
-
Yoon, J.-H.1
Bhatia, G.2
Prakash, S.3
Prakash, L.4
-
30
-
-
70849108164
-
Highly error-free role of DNA polymerase η in the replicative bypass of UV induced pyrimidine dimers in mouse and human cells
-
Yoon, J.-H., Prakash, L. & Prakash, S. (2009) Highly error-free role of DNA polymerase η in the replicative bypass of UV induced pyrimidine dimers in mouse and human cells. Proc. Natl Acad. Sci. USA 106, 18219-18224.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 18219-18224
-
-
Yoon, J.-H.1
Prakash, L.2
Prakash, S.3
|