Copper(II) sequentially loads onto the N-terminal amino group of the cellular prion protein before the individual octarepeats

Biochemistry

Volumn 53, Issue 24, 2014, Pages 3934-3939

  Stanyon, Helen F ^a   Patel, Khushbu ^a   Begum, Nadia ^a   Viles, John H ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; NEURODEGENERATIVE DISEASES; PROTEINS;

AMINO GROUP; CELLULAR PRION PROTEINS; FULL-LENGTH PROTEINS; MODEL PEPTIDES; N-TERMINALS; SCRAPIE INFECTION; SEQUENTIAL LOADING; TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES;

LOADING;

CELL PROTEIN; CUPRIC ION; PEPTIDE FRAGMENT; PRION PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HOMEOSTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCRAPIE; TITRIMETRY;

ANIMALS; BINDING SITES; CIRCULAR DICHROISM; COPPER; ELECTRON SPIN RESONANCE SPECTROSCOPY; MICE; PRIONS; PRPC PROTEINS;

EID: 84903191084     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500643b     Document Type: Article

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