Cytokines, diabetes mellitus and psychopathology: A challenging combination

Neuroendocrinology Letters

Volumn 35, Issue 2, 2014, Pages 159-169

  Kontoangelos, Konstantinos ^a,b   Papageorgiou, Charalabos C ^a,b   Raptis, Athanasios E ^a   Tsiotra, Panayoula ^c   Boutati, Eleni ^a   Lambadiari, Vaia ^a   Papadimitriou, George N ^a   Rabavilas, Andreas D ^b   Dimitriadis, George ^a   Raptis, Sotirios A ^a,c  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b UNIVERSITY MENTAL HEALTH RESEARCH INSTITUTE   (Greece)

^c Hellenic National Center for Research   (Greece)

Author keywords

Diabetes mellitus type 2; Hostility; IL 12; IL 6; Neuropsychiatric disorders; Psychotism; Tnf

Indexed keywords

HEMOGLOBIN A1C; INTERLEUKIN 12; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BRIEF SYMPTOM INVENTORY; DIABETES MELLITUS; DIABETIC PATIENT; EYSENCK PERSONALITY QUESTIONNAIRE; FEMALE; HOSTILITY; HUMAN; LIBIDO DISORDER; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; NEUROSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PSYCHOLOGICAL ASPECT; PSYCHOMETRY; QUESTIONNAIRE; RESTLESSNESS; SYMPTOM CHECKLIST 90; UNIVERSITY HOSPITAL; ZUNG SELF RATING DEPRESSION SCALE;

AGED; CYTOKINES; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INTERLEUKIN-12; INTERLEUKIN-6; MALE; MENTAL DISORDERS; MIDDLE AGED; PSYCHOMETRICS; QUESTIONNAIRES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84903187049     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Bendtzen K, Buschard K, Diamant K, Diamant M, Horn T, Svenson M (1989). Possible role of IL-1, tumor necrosis factor-alpha and IL-6 in insulin-dependent diabetes mellitus and autoimmune thyroid disease. Lymphokine Res. 8: 335-40. (Pubitemid 19215544)
2. Connor TJ, Kelliher P, Shen Y, Harkin A, Kelly JP, Leonard BE (2000). Effect of subchronic antidepressant treatments on behavioral neurochemical, and endocrine changes in the forced-swim test. Pharmacol Biochem Behav. 65: 591-7. (Pubitemid 30182501)
3. Connor TJ, Leonard BE (1998). Depression, stress and immunological activation: the role of cytokines in depressive disorders. Life Sci. 62: 583-606. (Pubitemid 28045567)
4. Costa PT, McCrae RR (1987). Neuroticism, somatic complaints, and disease: is the bark worse than the bite? J Pers. 55: 299-316.
5. Creange A, Barlovatz-Meimon G, Gherardi RK (1997). Cytokines and Peripheral nerve disorders. Eur Cytokine Net. 8: 145-151. (Pubitemid 28152140)
6. Crespo-Facorro B, Carraso-Marin E, Perez-Iglesias R, Pelayo-Teran JM, Fernandez-Prieto L, Leyva-Cobian F et al. (2008). Interleukin-12 plasma levels in drug-naive patients with a first episode of psychosis: Effects of antipsychotic drugs. Psychiatry Res. 15: 206-16.
7. Dandona P, Aljada A, Bandyopadhyay A (2004). Inflammation: the link between insulin Resistance, obesity and diabetes. Trends Immunol. 25: 4-7. (Pubitemid 38032801)
8. Derogatis L, Melisaratos N (1983). The brief symptom inventory: an introductory report. Psychological Medicine. 13: 595-605. (Pubitemid 13019024)
9. Dieperink E, Willenbring M, Ho SB (2000). Neuropsychiatric symptoms Associated With Hepatitis C and Interferon ALPHA: A Review. Am J Psychiatry. 157: 867-876. (Pubitemid 30412335)
10. Dimitriou E. EPQ personality Questionnaire (1986). Greek Validation in the Greek Population Dimitriou E. Engefalos. 23: 41-54, 1986.
11. Donias S, Karastergiou A, Manos N (1991). Validation of the Symptom Checklist-90-R in Greek Population Psychiatriki. 2: 42-48.
12. Eysenck HJ and Eysenck SBG (1975). Manual of the EPQ (Personality Questionnaire) hodder and Stoyghton Educational, London.
13. Foulds GA, Caine TM, Creasy MA (1960). Aspects of extra- and intro-punitive expression in mental illness. J Ment Sci. 106: 599-610.
14. Fountoulakis K, Iacovides A, Samolis S, Kleanthous S, Kaprinis S, Kaprinis G et al. (2001) Reliability, validity and psychometric properties of the Greek translation of the Zung depression rating scale. BMC Psychiatry. 1: 6.
15. Freitas-Foss MC, Foss NT, Donadi EA, Foss MC (2008). Effect of the glycemic control on intracellular cytokine production from peripheral blood mononuclear cells of type 1 and type 2 diabetic patients. Diabetes Research Clin pract. 82: 329-34.
16. Gabbay V, Coffey BJ, Guttman LE, Gottlieb L, Katz Y, Babb JS et al. (2009). A cytokine study in children and adolescents with Tourette's disorder. Prog Neoropsychopharmacol Biol Psychiatry. 31: 967-71.
17. Gordon D, Fisher SG, Wilson M, Fergus E, Paterson KR, Semple CG (1993). Psychological factors. And their relationship to diabetes control. Diabet Med. 10: 530-534. (Pubitemid 23189757)
18. Hepburn DA, Langan SJ, Deary IJ, Macleod KM, Frier BM (1994). Psychological and demographic correlates of glycaemic control in adult patients with Type 1 diabetes. Diabet Med. 11: 578-582. (Pubitemid 24227359)
19. Hodgson RJ, Rachman S (1977). Obsessional-compulsive complaints. Behav Res & Therapy. 15: 389-395. (Pubitemid 8203150)
20. Hounie AG, Cappi C, Cordeiro Q, Sampaio AS, Moraes I, Rosario MC (2008).TNF-alpha polymorphisms are associated with obsessive-compulsive disorder. Neurosci Lett. 12: 86-90.
21. Kahl KG, Bester M, Greggersen W, Rudolf S, Dibbelt L, Stoeckelhuber BM. Visceral fat deposition and insulin sensitivity in depressed women with and without comorbid borderline personality disorder. Psychosom Med. 67: 407-12.
22. Kiecolt-Glaser JK, Marucha PT, Malarkey WB, Mercado AM, Glaser R (1995). Slowing of wound hea ling by psychological stress. 346: 1194-1196.
23. Kim DJ, Kim W, Yoon SJ, Choi BM, Kim JS, Go HJ et al. (2003). Effects of alcohol hangover on cytokine production in healthy subjects. Alcohol. 31: 167-70. (Pubitemid 38018983)
24. Kim YK, Lee SW, Kim SH, Shim SH, Han SW, Choi SH et al. (2008). Differences in cytokines between nonsuicidal patients and suicidal patients in major depression. Prog Neuropsychopharmacol Biol Psychiatry. 32: 356-361.
25. Kim YK, Suh IB, Kim H, Han CS, Lim CS, Choi SH et al. (2002). The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: effects of psychotropic drugs. Mol Psychiatry. 7: 1107-14. (Pubitemid 36044270)
26. Lane J, McCaskill C, Williams P, Parekh P, Feinglos M, Surwit R (2000). Personality Correlates of glycemic control in Type 2 Diabetes. Diabetes Care. 23: 1321-1325.
27. Libby P, Ridker PM, Maseri A (2002). Inflammation and atherosclerosis. Circulation. 105: 1135-1143. (Pubitemid 34212626)
28. Maes M (1995). Evidence for an immune response in major depression: a review and Hypothesis. Prog Neuro Psychopharmacol Biol Psychiatry. 19: 11-38.
29. Mikova O, Yakimova R, Bosman E, Kenis G, Maes M (2001). Increased serum necrosis factor alpha concentrations in major depression and multiple sclerosis. Eur Neuropsychopharmacol. 11: 203-8. (Pubitemid 32611587)
30. Muller N, Ackenheil M (1998). Psychoneuroimmunology and the cytokine action in the CNS: implications for psychiatric disorders. Prog Neuropsychopharmacol Biol Psychiatry. 22: 1-33. (Pubitemid 28096427)
31. O'Brien S, Scott L, Dinan TG (2004). Cytokines: abnormalities in major depression and implications for pharmacological treatment. Hum Psychopharmacol. 19: 397-403. (Pubitemid 39172804)
32. O'Conell, Taba M, Nomizo A, Foss Freitas MC, Suaid FA, Uyemura SA et al. (2008). Effects of periodontal therapy on glycemic control and inflammatory markers. J Periodontol. 79: 774-83.
33. Parissis JT, Adamopoulos S, Rigas A, Kostakis G, Karatzas D, Venetsanou K et al. (2004). Comparison of Circulating Proinflammatory Cytokines and Soluble Apoptosis Mediators in Patients With Chronic Heart Failure With Versus Without Symptoms of Depression. Am J Cardiol. 94: 1326-1328. (Pubitemid 39469963)
34. Pickup JC (2004). Inflammation and Activated Innate Immunity in the Pathogenesis of Type 2 Diabetes. Diabetes Care. 27: 813-823.
35. Pollmacher T, Hinze-Selch D, Mullington J (1996). Effects of clozapine on plasma cytokine and soluble cytokine receptor levels. J Clin Psychopharmacol. 16: 403-409. (Pubitemid 26352672)
36. Rachman J, Levy JC, Barrow BA, Manley SE, Turner RC (1997). Relative hyperproinsulinemia of NIDDM persists despite the reduction of hyperglycemia with insulin of sulfonylurea therapy. Diabetes. 46: 1557-62. (Pubitemid 27411229)
37. Rachman S (1974). Primary obssesional slowness. Behav. Res and Ther. 11: 463-4.
38. Rief W, Pilger F, Ihle D, Bosmans E, Egyed B, Maes M (2001). Immunological differences Between patients with major depression and somatization syndrome. Psychiatry Res. 105: 165-174. (Pubitemid 34117644)
39. Satoh Jo, Yagihashi S, Toyota T (2003). The possible role of Tumor Necrosis Factor-α in Diabetic Polyneuropathy. Experimental Diabesity Res 4: 65-71.
40. Schmitt A, Bertsch T, Tost H, Bergmann A, Henning U, Klimke A et al. (2005). Increased serum interleukin 1-Beta and interleukin-6 in elderly, chronic schizophrenic patients on stable antipsychotic medication. Neuropsychiatr Dis Treat. 1: 171-7.
41. Shephard RJ (2002). Cytokine Responses to Physical Activity, with Particular Reference to IL-6: Sources, Actions, and clinical Implications. Crit Rev Immunol. 22: 165-182.
42. Singh NA, Clements KM, Singh MA (2001). The efficacy of exercise as a long-term antidepressant in elderly subjects: a randomized controlled trial. J Gerontol A Biol Sci Med Sci. 56: M497-504. (Pubitemid 32717790)
43. Sluzewska A, Sobieska M, Rybakowski JK (1997). Changes in acute phase proteins during lithium potentiation of antidepressants in refractory depression. Neuropsychobiology. 35: 123-127. (Pubitemid 27196534)
44. Song Y, Zhou D, Guan Z, Wang X (2007). Disturbance of serum interleukin-2 and interleukin-8 levels in posttraumatic and non-posttraumatic stress disorder earthquake survivors in northern China. Neuroimmunomodulation. 14: 248-54. (Pubitemid 351339991)
45. Sonikian M, Metaxaki P, Papavasileiou D, Boufidou F, Nikolaou C, Vlassopoulos D et al. (2010). Effects of Interleukin-6 on Depression Risk in Dialysis Patients. Am J Nephrol. 31: 303-308.
46. Stoney CM, Engebretson TO (2000). Plasma homocysteine concentrations are positively associated with hostility and anger. Life Sci. 66: 2267-75. (Pubitemid 30256627)
47. Suarez EC (2003). Joint effect of hostility and severity of depressive symptoms on plasma interleukin-6 concentration. Psychosom Med. 65: 523-7.
48. Sutin AR, Terracdano A, Deiana B, Naitza S, Ferrucci L, Uda M et al. (2010). High Neurotism and Low Conscientiousness are associated with interleukin-6. Psychol Med. 40: 1485-93.
49. Taylor MD, Frier BM, Gold AE, Deary IJ (2003). Psychosocial factors and diabetes-related. Outcomes following diagnosis of Type 1 diabetes in adults: The Edinburg Prospective Diabetes Study. Diabetic Medicine. 20: 135-146. (Pubitemid 36269655)
50. Temelkova-Kurktschiev T, Henkel E, Koehler C, Karrei K, Hanefield M (2002). Sub-clinical inflammation in newly detected type II diabetes and impaired Glucose tolerance. Diabetologia. 45: 151. (Pubitemid 34118556)
51. Wegner M, Winiarska H, Bobkiewicz-Kozlowska T, Dworacka M (2008). IL-12 serum levels in patients with type 2 diabetes treated with sulphonylureas. Cytokine. 42: 312-6.
52. Zung WA (1965). Self-Rating Scale. Archives of General Psychiatry. 12: 63-70.