-
1
-
-
0024262589
-
Cellular uptake of the tat protein from human immunodeficiency virus
-
Frankel, A. D. and Pabo, C. O. (1988) Cellular uptake of the tat protein from human immunodeficiency virus Cell 55, 1189-1193
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
2
-
-
0024209811
-
Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein
-
Green, M. and Loewenstein, P. M. (1988) Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein Cell 55, 1179-1188
-
(1988)
Cell
, vol.55
, pp. 1179-1188
-
-
Green, M.1
Loewenstein, P.M.2
-
4
-
-
77951902057
-
Arginine-rich cell-penetrating peptides
-
Schmidt, N., Mishra, A., Lai, G. H., and Wong, G. C. (2010) Arginine-rich cell-penetrating peptides FEBS Lett. 584, 1806-1813
-
(2010)
FEBS Lett.
, vol.584
, pp. 1806-1813
-
-
Schmidt, N.1
Mishra, A.2
Lai, G.H.3
Wong, G.C.4
-
5
-
-
13844272399
-
Membrane-permeable arginine-rich peptides and the translocation mechanisms
-
Futaki, S. (2005) Membrane-permeable arginine-rich peptides and the translocation mechanisms Adv. Drug Delivery Rev. 57, 547-558
-
(2005)
Adv. Drug Delivery Rev.
, vol.57
, pp. 547-558
-
-
Futaki, S.1
-
6
-
-
45749120326
-
Cell-penetrating peptides as delivery vehicles for biology and medicine
-
Stewart, K. M., Horton, K. L., and Kelley, S. O. (2008) Cell-penetrating peptides as delivery vehicles for biology and medicine Org. Biomol. Chem. 6, 2242-2255
-
(2008)
Org. Biomol. Chem.
, vol.6
, pp. 2242-2255
-
-
Stewart, K.M.1
Horton, K.L.2
Kelley, S.O.3
-
7
-
-
23944483437
-
Cell-penetrating peptides: Tools for intracellular delivery of therapeutics
-
Deshayes, S., Morris, M. C., Divita, G., and Heitz, F. (2005) Cell-penetrating peptides: Tools for intracellular delivery of therapeutics Cell. Mol. Life Sci. 62, 1839-1849
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 1839-1849
-
-
Deshayes, S.1
Morris, M.C.2
Divita, G.3
Heitz, F.4
-
8
-
-
33749656235
-
Molecular Transporters: Synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging
-
Goun, E. A., Pillow, T. H., Jones, L. R., Rothbard, J. B., and Wender, P. A. (2005) Molecular Transporters: Synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging ChemBioChem 7, 1497-1515
-
(2005)
ChemBioChem
, vol.7
, pp. 1497-1515
-
-
Goun, E.A.1
Pillow, T.H.2
Jones, L.R.3
Rothbard, J.B.4
Wender, P.A.5
-
9
-
-
0033678653
-
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation
-
Rothbard, J. B., Garlington, S., Lin, Q., Kirschberg, T., Kreider, E., McGrane, P. L., Wender, P. A., and Khavari, P. A. (2000) Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation Nat. Med. 6, 1253-1257
-
(2000)
Nat. Med.
, vol.6
, pp. 1253-1257
-
-
Rothbard, J.B.1
Garlington, S.2
Lin, Q.3
Kirschberg, T.4
Kreider, E.5
McGrane, P.L.6
Wender, P.A.7
Khavari, P.A.8
-
10
-
-
0037255080
-
Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells
-
Nori, A., Jensen, K. D., Tijerina, M., Kopeckova, P., and Kopecek, J. (2003) Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells Bioconjugate Chem. 14, 44-50
-
(2003)
Bioconjugate Chem.
, vol.14
, pp. 44-50
-
-
Nori, A.1
Jensen, K.D.2
Tijerina, M.3
Kopeckova, P.4
Kopecek, J.5
-
11
-
-
84863951245
-
Peptide vectors for the nonviral delivery of nucleic acids
-
Hoyer, J. and Neundorf, I. (2012) Peptide vectors for the nonviral delivery of nucleic acids Acc. Chem. Res. 45, 1048-1056
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 1048-1056
-
-
Hoyer, J.1
Neundorf, I.2
-
12
-
-
0035854707
-
Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells
-
Eguchi, A., Akuta, T., Okuyama, H., Senda, T., Yokoi, H., Inokuchi, H., Fujita, S., Hayakawa, T., Takeda, K., Hasegawa, M., and Nakanishi, M. (2001) Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells J. Biol. Chem. 276, 26204-26210
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26204-26210
-
-
Eguchi, A.1
Akuta, T.2
Okuyama, H.3
Senda, T.4
Yokoi, H.5
Inokuchi, H.6
Fujita, S.7
Hayakawa, T.8
Takeda, K.9
Hasegawa, M.10
Nakanishi, M.11
-
13
-
-
84863954601
-
Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides
-
Nakase, I., Akita, H., Kogure, K., Graslund, A., Langel, U., Harashima, H., and Futaki, S. (2012) Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides Acc. Chem. Res. 45, 1132-1139
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 1132-1139
-
-
Nakase, I.1
Akita, H.2
Kogure, K.3
Graslund, A.4
Langel, U.5
Harashima, H.6
Futaki, S.7
-
14
-
-
79956015439
-
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo
-
Andaloussi, S. E., Lehto, T., Mager, I., Rosenthal-Aizman, K., Oprea, I. I., Simonson, O. E., Sork, H., Ezzat, K., Copolovici, D. M., Kurrikoff, K., Viola, J. R., Zaghloul, E. M., Sillard, R., Johansson, H. J., Said Hassane, F., Guterstam, P., Suhorutsenko, J., Moreno, P. M., Oskolkov, N., Halldin, J., Tedebark, U., Metspalu, A., Lebleu, B., Lehtio, J., Smith, C. I., and Langel, U. (2011) Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo Nucleic Acids Res. 39, 3972-3987
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 3972-3987
-
-
Andaloussi, S.E.1
Lehto, T.2
Mager, I.3
Rosenthal-Aizman, K.4
Oprea, I.I.5
Simonson, O.E.6
Sork, H.7
Ezzat, K.8
Copolovici, D.M.9
Kurrikoff, K.10
Viola, J.R.11
Zaghloul, E.M.12
Sillard, R.13
Johansson, H.J.14
Said Hassane, F.15
Guterstam, P.16
Suhorutsenko, J.17
Moreno, P.M.18
Oskolkov, N.19
Halldin, J.20
Tedebark, U.21
Metspalu, A.22
Lebleu, B.23
Lehtio, J.24
Smith, C.I.25
Langel, U.26
more..
-
15
-
-
61849162695
-
SiRNA conjugate delivery systems
-
Jeong, J. H., Mok, H., Oh, Y. K., and Park, T. G. (2009) siRNA conjugate delivery systems Bioconjugate Chem. 20, 5-14
-
(2009)
Bioconjugate Chem.
, vol.20
, pp. 5-14
-
-
Jeong, J.H.1
Mok, H.2
Oh, Y.K.3
Park, T.G.4
-
16
-
-
0842346326
-
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
-
Muratovska, A. and Eccles, M. R. (2004) Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells FEBS Lett. 558, 63-68
-
(2004)
FEBS Lett.
, vol.558
, pp. 63-68
-
-
Muratovska, A.1
Eccles, M.R.2
-
17
-
-
13844256697
-
Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer
-
Wadia, J. S. and Dowdy, S. F. (2005) Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer Adv. Drug Delivery Rev. 57, 579-596
-
(2005)
Adv. Drug Delivery Rev.
, vol.57
, pp. 579-596
-
-
Wadia, J.S.1
Dowdy, S.F.2
-
18
-
-
0035374402
-
Cellular translocation of proteins by transportan
-
Pooga, M., Kut, C., Kihlmark, M., Hallbrink, M., Fernaeus, S., Raid, R., Land, T., Hallberg, E., Bartfai, T., and Langel, U. (2001) Cellular translocation of proteins by transportan FASEB J. 15, 1451-1453
-
(2001)
FASEB J.
, vol.15
, pp. 1451-1453
-
-
Pooga, M.1
Kut, C.2
Kihlmark, M.3
Hallbrink, M.4
Fernaeus, S.5
Raid, R.6
Land, T.7
Hallberg, E.8
Bartfai, T.9
Langel, U.10
-
19
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze, S. R., Ho, A., Vocero-Akbani, A., and Dowdy, S. F. (1999) In vivo protein transduction: Delivery of a biologically active protein into the mouse Science 285, 1569-1572
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
20
-
-
0033106072
-
High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates
-
Josephson, L., Tung, C. H., Moore, A., and Weissleder, R. (1999) High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates Bioconjugate Chem. 10, 186-191
-
(1999)
Bioconjugate Chem.
, vol.10
, pp. 186-191
-
-
Josephson, L.1
Tung, C.H.2
Moore, A.3
Weissleder, R.4
-
21
-
-
13844298046
-
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
-
Gupta, B., Levchenko, T. S., and Torchilin, V. P. (2005) Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides Adv. Drug Delivery Rev. 57, 637-651
-
(2005)
Adv. Drug Delivery Rev.
, vol.57
, pp. 637-651
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
22
-
-
0034893552
-
Nanostructured materials designed for cell binding and transduction
-
Liu, J., Zhang, Q., Remsen, E. E., and Wooley, K. L. (2001) Nanostructured materials designed for cell binding and transduction Biomacromolecules 2, 362-368
-
(2001)
Biomacromolecules
, vol.2
, pp. 362-368
-
-
Liu, J.1
Zhang, Q.2
Remsen, E.E.3
Wooley, K.L.4
-
23
-
-
27644509147
-
Cell-penetrating peptides: A comparative membrane toxicity study
-
Saar, K., Lindgren, M., Hansen, M., Eiriksdottir, E., Jiang, Y., Rosenthal-Aizman, K., Sassian, M., and Langel, U. (2005) Cell-penetrating peptides: A comparative membrane toxicity study Anal. Biochem. 345, 55-65
-
(2005)
Anal. Biochem.
, vol.345
, pp. 55-65
-
-
Saar, K.1
Lindgren, M.2
Hansen, M.3
Eiriksdottir, E.4
Jiang, Y.5
Rosenthal-Aizman, K.6
Sassian, M.7
Langel, U.8
-
24
-
-
81255143202
-
Cell-penetrating peptides, PepFects, show no evidence of toxicity and immunogenicity in vitro and in vivo
-
Suhorutsenko, J., Oskolkov, N., Arukuusk, P., Kurrikoff, K., Eriste, E., Copolovici, D. M., and Langel, U. (2011) Cell-penetrating peptides, PepFects, show no evidence of toxicity and immunogenicity in vitro and in vivo Bioconjugate Chem. 22, 2255-2262
-
(2011)
Bioconjugate Chem.
, vol.22
, pp. 2255-2262
-
-
Suhorutsenko, J.1
Oskolkov, N.2
Arukuusk, P.3
Kurrikoff, K.4
Eriste, E.5
Copolovici, D.M.6
Langel, U.7
-
25
-
-
0036523467
-
Cellular uptake studies with β-peptides
-
Rueping, M., Mahajan, Y., Sauer, M., and Seebach, D. (2002) Cellular uptake studies with β-peptides ChemBioChem 3, 257-259
-
(2002)
ChemBioChem
, vol.3
, pp. 257-259
-
-
Rueping, M.1
Mahajan, Y.2
Sauer, M.3
Seebach, D.4
-
26
-
-
70450169425
-
Oligocarbonate molecular transporters: Oligomerization-based syntheses and cell-penetrating studies
-
Cooley, C. B., Trantow, B. M., Nederberg, F., Kiesewetter, M. K., Hedrick, J. L., Waymouth, R. M., and Wender, P. A. (2009) Oligocarbonate molecular transporters: Oligomerization-based syntheses and cell-penetrating studies J. Am. Chem. Soc. 131, 16401-16403
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 16401-16403
-
-
Cooley, C.B.1
Trantow, B.M.2
Nederberg, F.3
Kiesewetter, M.K.4
Hedrick, J.L.5
Waymouth, R.M.6
Wender, P.A.7
-
27
-
-
4544263874
-
Enhancing membrane permeability by fatty acylation of oligoarginine peptides
-
Pham, W., Kircher, M. F., Weissleder, R., and Tung, C. H. (2004) Enhancing membrane permeability by fatty acylation of oligoarginine peptides ChemBioChem 5, 1148-1151
-
(2004)
ChemBioChem
, vol.5
, pp. 1148-1151
-
-
Pham, W.1
Kircher, M.F.2
Weissleder, R.3
Tung, C.H.4
-
28
-
-
38049156027
-
Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes
-
Herce, H. D. and Garcia, A. E. (2007) Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes Proc. Natl. Acad. Sci. U.S.A. 104, 20805-20810
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20805-20810
-
-
Herce, H.D.1
Garcia, A.E.2
-
29
-
-
84860529568
-
Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells
-
Hirose, H., Takeuchi, T., Osakada, H., Pujals, S., Katayama, S., Nakase, I., Kobayashi, S., Haraguchi, T., and Futaki, S. (2012) Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells Mol. Ther. 20, 984-993
-
(2012)
Mol. Ther.
, vol.20
, pp. 984-993
-
-
Hirose, H.1
Takeuchi, T.2
Osakada, H.3
Pujals, S.4
Katayama, S.5
Nakase, I.6
Kobayashi, S.7
Haraguchi, T.8
Futaki, S.9
-
30
-
-
70350023192
-
Arginine-rich peptides destabilize the plasma membrane, consistent with a pore formation translocation mechanism of cell-penetrating peptides
-
Herce, H. D., Garcia, A. E., Litt, J., Kane, R. S., Martin, P., Enrigue, N., Rebolledo, A., and Milesi, V. (2009) Arginine-rich peptides destabilize the plasma membrane, consistent with a pore formation translocation mechanism of cell-penetrating peptides Biophys. J. 97, 1917-1925
-
(2009)
Biophys. J.
, vol.97
, pp. 1917-1925
-
-
Herce, H.D.1
Garcia, A.E.2
Litt, J.3
Kane, R.S.4
Martin, P.5
Enrigue, N.6
Rebolledo, A.7
Milesi, V.8
-
31
-
-
58249095956
-
The membrane repair response masks membrane disturbances caused by cell-penetrating peptide uptake
-
Palm-Apergi, C., Lorents, A., Padari, K., Pooga, M., and Hallbrink, M. (2009) The membrane repair response masks membrane disturbances caused by cell-penetrating peptide uptake FASEB J. 23, 214-223
-
(2009)
FASEB J.
, vol.23
, pp. 214-223
-
-
Palm-Apergi, C.1
Lorents, A.2
Padari, K.3
Pooga, M.4
Hallbrink, M.5
-
32
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
-
Richard, J. P., Melikov, K., Brooks, H., Prevot, P., Lebleu, B., and Chernomordik, L. V. (2005) Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors J. Biol. Chem. 280, 15300-15306
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
Melikov, K.2
Brooks, H.3
Prevot, P.4
Lebleu, B.5
Chernomordik, L.V.6
-
33
-
-
0042355293
-
Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time
-
Ferrari, A., Pellegrini, V., Arcangeli, C., Fittipaldi, A., Giacca, M., and Beltram, F. (2003) Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time Mol. Ther. 8, 284-294
-
(2003)
Mol. Ther.
, vol.8
, pp. 284-294
-
-
Ferrari, A.1
Pellegrini, V.2
Arcangeli, C.3
Fittipaldi, A.4
Giacca, M.5
Beltram, F.6
-
34
-
-
0141446039
-
Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins
-
Fittipaldi, A., Ferrari, A., Zoppe, M., Arcangeli, C., Pellegrini, V., Beltram, F., and Giacca, M. (2003) Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins J. Biol. Chem. 278, 34141-34149
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34141-34149
-
-
Fittipaldi, A.1
Ferrari, A.2
Zoppe, M.3
Arcangeli, C.4
Pellegrini, V.5
Beltram, F.6
Giacca, M.7
-
35
-
-
11844268027
-
Cationic TAT peptide transduction domain enters cells by macropinocytosis
-
Kaplan, I. M., Wadia, J. S., and Dowdy, S. F. (2005) Cationic TAT peptide transduction domain enters cells by macropinocytosis J. Controlled Release 102, 247-253
-
(2005)
J. Controlled Release
, vol.102
, pp. 247-253
-
-
Kaplan, I.M.1
Wadia, J.S.2
Dowdy, S.F.3
-
36
-
-
33846223900
-
Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis
-
Nakase, I., Tadokoro, A., Kawabata, N., Takeuchi, T., Katoh, H., Hiramoto, K., Negishi, M., Nomizu, M., Sugiura, Y., and Futaki, S. (2007) Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis Biochemistry 46, 492-501
-
(2007)
Biochemistry
, vol.46
, pp. 492-501
-
-
Nakase, I.1
Tadokoro, A.2
Kawabata, N.3
Takeuchi, T.4
Katoh, H.5
Hiramoto, K.6
Negishi, M.7
Nomizu, M.8
Sugiura, Y.9
Futaki, S.10
-
37
-
-
34250835903
-
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides
-
Duchardt, F., Fotin-Mleczek, M., Schwarz, H., Fischer, R., and Brock, R. (2007) A comprehensive model for the cellular uptake of cationic cell-penetrating peptides Traffic 8, 848-866
-
(2007)
Traffic
, vol.8
, pp. 848-866
-
-
Duchardt, F.1
Fotin-Mleczek, M.2
Schwarz, H.3
Fischer, R.4
Brock, R.5
-
38
-
-
58149099412
-
Comparison of cellular uptake using 22 CPPs in 4 different cell lines
-
Mueller, J., Kretzschmar, I., Volkmer, R., and Boisguerin, P. (2008) Comparison of cellular uptake using 22 CPPs in 4 different cell lines Bioconjugate Chem. 19, 2363-2374
-
(2008)
Bioconjugate Chem.
, vol.19
, pp. 2363-2374
-
-
Mueller, J.1
Kretzschmar, I.2
Volkmer, R.3
Boisguerin, P.4
-
39
-
-
20444403719
-
Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides
-
Maiolo, J. R., Ferrer, M., and Ottinger, E. A. (2005) Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides Biochim. Biophys. Acta 1712, 161-172
-
(2005)
Biochim. Biophys. Acta
, vol.1712
, pp. 161-172
-
-
Maiolo, J.R.1
Ferrer, M.2
Ottinger, E.A.3
-
40
-
-
65549133368
-
Delivery of macromolecules using arginine-rich cell-penetrating peptides: Ways to overcome endosomal entrapment
-
El-Sayed, A., Futaki, S., and Harashima, H. (2009) Delivery of macromolecules using arginine-rich cell-penetrating peptides: Ways to overcome endosomal entrapment AAPS J. 11, 13-22
-
(2009)
AAPS J.
, vol.11
, pp. 13-22
-
-
El-Sayed, A.1
Futaki, S.2
Harashima, H.3
-
41
-
-
79957460418
-
Endosomal escape pathways for delivery of biologicals
-
Varkouhi, A. K., Scholte, M., Storm, G., and Haisma, H. J. (2011) Endosomal escape pathways for delivery of biologicals J. Controlled Release 151, 220-228
-
(2011)
J. Controlled Release
, vol.151
, pp. 220-228
-
-
Varkouhi, A.K.1
Scholte, M.2
Storm, G.3
Haisma, H.J.4
-
42
-
-
84864402585
-
Arginine topology controls escape of minimally cationic proteins from early endosomes to the cytoplasm
-
Appelbaum, J. S., LaRochelle, J. R., Smith, B. A., Balkin, D. M., Holub, J. M., and Schepartz, A. (2012) Arginine topology controls escape of minimally cationic proteins from early endosomes to the cytoplasm Chem. Biol. 19, 819-830
-
(2012)
Chem. Biol.
, vol.19
, pp. 819-830
-
-
Appelbaum, J.S.1
Larochelle, J.R.2
Smith, B.A.3
Balkin, D.M.4
Holub, J.M.5
Schepartz, A.6
-
43
-
-
84874067992
-
Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs
-
Qian, Z., Liu, T., Liu, Y. Y., Briesewitz, R., Barrios, A. M., Jhiang, S. M., and Pei, D. (2013) Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs ACS Chem. Biol. 8, 423-431
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 423-431
-
-
Qian, Z.1
Liu, T.2
Liu, Y.Y.3
Briesewitz, R.4
Barrios, A.M.5
Jhiang, S.M.6
Pei, D.7
-
44
-
-
84877755819
-
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides
-
Lattig-Tunnemann, G., Prinz, M., Hoffmann, D., Behlke, J., Palm-Apergi, C., Morano, I., Herce, H. D., and Cardoso, M. C. (2011) Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides Nat. Commun. 2, 453
-
(2011)
Nat. Commun.
, vol.2
, pp. 453
-
-
Lattig-Tunnemann, G.1
Prinz, M.2
Hoffmann, D.3
Behlke, J.4
Palm-Apergi, C.5
Morano, I.6
Herce, H.D.7
Cardoso, M.C.8
-
45
-
-
80053494111
-
Cell-penetrating homochiral cyclic peptides as nuclear-targeting molecular transporters
-
Mandal, D., Nasrolahi Shirazi, A., and Parang, K. (2011) Cell-penetrating homochiral cyclic peptides as nuclear-targeting molecular transporters Angew. Chem., Int. Ed. 50, 9633-9637
-
(2011)
Angew. Chem., Int. Ed.
, vol.50
, pp. 9633-9637
-
-
Mandal, D.1
Nasrolahi Shirazi, A.2
Parang, K.3
-
46
-
-
84869593940
-
Enhanced activity of cyclic transporter sequences driven by phase behavior of peptide-lipid complexes
-
Zhao, K., Choe, U. J., Kamei, D. T., and Wong, G. C. L. (2012) Enhanced activity of cyclic transporter sequences driven by phase behavior of peptide-lipid complexes Soft Matter 8, 6430-6433
-
(2012)
Soft Matter
, vol.8
, pp. 6430-6433
-
-
Zhao, K.1
Choe, U.J.2
Kamei, D.T.3
Wong, G.C.L.4
-
47
-
-
84882282136
-
Screening bicyclic peptide libraries for protein-protein interaction inhibitor: Discovery of a tumor necrosis factor-α antagonist
-
Lian, W., Upadhyaya, P., Rhodes, C. A., Liu, Y., and Pei, D. (2013) Screening bicyclic peptide libraries for protein-protein interaction inhibitor: Discovery of a tumor necrosis factor-α antagonist J. Am. Chem. Soc. 135, 11990-11995
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 11990-11995
-
-
Lian, W.1
Upadhyaya, P.2
Rhodes, C.A.3
Liu, Y.4
Pei, D.5
-
48
-
-
26844519475
-
Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine
-
Mitra, S. and Barrios, A. M. (2005) Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine Bioorg. Med. Chem. Lett. 15, 5124-5145
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 5124-5145
-
-
Mitra, S.1
Barrios, A.M.2
-
49
-
-
84865538949
-
High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45
-
Stanford, S. M., Panchal, R. G., Walker, L. M., Wu, D. J., Falk, M. D., Mitra, S., Damle, S. S., Ruble, D., Kaltcheva, T., Zhang, S., Zhang, Z. Y., Bavari, S., Barrios, A. M., and Bottini, N. (2012) High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45 Proc. Natl. Acad. Sci. U.S.A. 109, 13972-13977
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 13972-13977
-
-
Stanford, S.M.1
Panchal, R.G.2
Walker, L.M.3
Wu, D.J.4
Falk, M.D.5
Mitra, S.6
Damle, S.S.7
Ruble, D.8
Kaltcheva, T.9
Zhang, S.10
Zhang, Z.Y.11
Bavari, S.12
Barrios, A.M.13
Bottini, N.14
-
50
-
-
27644508250
-
Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase
-
Yin, J., Straight, P. D., McLoughlin, S. M., Zhou, Z., Lin, A. J., Golan, D. E., Kelleher, N. L., Kolter, R., and Walsh, C. T. (2005) Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase Proc. Natl. Acad. Sci. U.S.A. 102, 15815-15820
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 15815-15820
-
-
Yin, J.1
Straight, P.D.2
McLoughlin, S.M.3
Zhou, Z.4
Lin, A.J.5
Golan, D.E.6
Kelleher, N.L.7
Kolter, R.8
Walsh, C.T.9
-
51
-
-
84890456140
-
Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics
-
Holub, J. M., LaRochelle, J. R., Appelbaum, J. S., and Schepartz, A. (2013) Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics Biochemistry 52, 9036-6046
-
(2013)
Biochemistry
, vol.52
, pp. 9036-6046
-
-
Holub, J.M.1
Larochelle, J.R.2
Appelbaum, J.S.3
Schepartz, A.4
-
52
-
-
80052233389
-
Endosome maturation
-
Huotari, J. and Helenius, A. (2011) Endosome maturation EMBO J. 30, 3481-3500
-
(2011)
EMBO J.
, vol.30
, pp. 3481-3500
-
-
Huotari, J.1
Helenius, A.2
-
53
-
-
24144442691
-
Rab conversion as a mechanism of progression from early to late endosomes
-
Rink, J., Ghigo, E., Kalaidzidis, Y., and Zerial, M. (2005) Rab conversion as a mechanism of progression from early to late endosomes Cell 122, 735-749
-
(2005)
Cell
, vol.122
, pp. 735-749
-
-
Rink, J.1
Ghigo, E.2
Kalaidzidis, Y.3
Zerial, M.4
-
54
-
-
24944573100
-
A high-throughput assay for assessing the cell permeability of combinatorial libraries
-
Yu, P., Liu, B., and Kodadek, T. (2005) A high-throughput assay for assessing the cell permeability of combinatorial libraries Nat. Biotechnol. 23, 746-751
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 746-751
-
-
Yu, P.1
Liu, B.2
Kodadek, T.3
-
55
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
Pratt, W. B. and Toft, D. O. (1997) Steroid receptor interactions with heat shock protein and immunophilin chaperones Endocr. Rev. 18, 306-360
-
(1997)
Endocr. Rev.
, vol.18
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
56
-
-
0023441954
-
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
-
Picard, D. and Yamamoto, K. R. (1987) Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor EMBO J. 6, 3333-3340
-
(1987)
EMBO J.
, vol.6
, pp. 3333-3340
-
-
Picard, D.1
Yamamoto, K.R.2
-
57
-
-
33646892646
-
Dynasore, a cell-permeable inhibitor of dynamin
-
Macia, E., Ehrlich, M., Massol, R., Boucrot, E., Brunner, C., and Kirchhausen, T. (2006) Dynasore, a cell-permeable inhibitor of dynamin Dev. Cell 10, 839-850
-
(2006)
Dev. Cell
, vol.10
, pp. 839-850
-
-
Macia, E.1
Ehrlich, M.2
Massol, R.3
Boucrot, E.4
Brunner, C.5
Kirchhausen, T.6
-
58
-
-
77149129342
-
Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling
-
Koivusalo, M., Welch, C., Hayashi, H., Scott, C. C., Kim, M., Alexander, T., Touret, N., Hahn, K. M., and Grinstein, S. (2010) Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling J. Cell Biol. 188, 547-563
-
(2010)
J. Cell Biol.
, vol.188
, pp. 547-563
-
-
Koivusalo, M.1
Welch, C.2
Hayashi, H.3
Scott, C.C.4
Kim, M.5
Alexander, T.6
Touret, N.7
Hahn, K.M.8
Grinstein, S.9
-
59
-
-
0032931988
-
Extraction of cholesterol with methyl-β-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
-
Rodal, S. K., Skretting, G., Garred, O., Vilhardt, F., van Deurs, B., and Sandvig, K. (1999) Extraction of cholesterol with methyl-β-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles Mol. Biol. Cell 10, 961-974
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 961-974
-
-
Rodal, S.K.1
Skretting, G.2
Garred, O.3
Vilhardt, F.4
Van Deurs, B.5
Sandvig, K.6
-
60
-
-
0025925091
-
+-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
-
+-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells J. Biol. Chem. 266, 17707-17712
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 17707-17712
-
-
Yoshimori, T.1
Yamamoto, A.2
Moriyama, Y.3
Futai, M.4
Tashiro, Y.5
-
61
-
-
0028786852
-
Evidence for phophatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5
-
Li, G., D'Souza-Schorey, C., Barbieri, M. A., Roberts, R. L., Klippel, A., Williams, L. T., and Stahl, P. D. (1995) Evidence for phophatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5 Proc. Natl. Acad. Sci. U.S.A. 92, 10207-10211
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 10207-10211
-
-
Li, G.1
D'Souza-Schorey, C.2
Barbieri, M.A.3
Roberts, R.L.4
Klippel, A.5
Williams, L.T.6
Stahl, P.D.7
-
62
-
-
0028261425
-
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
-
Stenmark, H., Parton, R. G., Steele-Mortimer, O., Lutcke, A., Gruenberg, J., and Zerial, M. (1994) Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis EMBO J. 13, 1287-1296
-
(1994)
EMBO J.
, vol.13
, pp. 1287-1296
-
-
Stenmark, H.1
Parton, R.G.2
Steele-Mortimer, O.3
Lutcke, A.4
Gruenberg, J.5
Zerial, M.6
-
63
-
-
0033215196
-
Multiple interactions of HIV-1 Tat protein with size-defined heparin oligosaccharides
-
Rusnati, M., Tulipano, G., Spillmann, D., Tanghetti, E., Oreste, P., Zoppetti, G., Giacca, M., and Presta, M. (1999) Multiple interactions of HIV-1 Tat protein with size-defined heparin oligosaccharides J. Biol. Chem. 274, 28198-28205
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28198-28205
-
-
Rusnati, M.1
Tulipano, G.2
Spillmann, D.3
Tanghetti, E.4
Oreste, P.5
Zoppetti, G.6
Giacca, M.7
Presta, M.8
-
64
-
-
0035793619
-
Internalization of HIV-1 tat requires cell surface heparin sulfate proteoglycans
-
Tyagi, M., Rusnati, M., Presta, M., and Giacca, M. (2001) Internalization of HIV-1 tat requires cell surface heparin sulfate proteoglycans J. Biol. Chem. 276, 3254-3261
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3254-3261
-
-
Tyagi, M.1
Rusnati, M.2
Presta, M.3
Giacca, M.4
-
65
-
-
0346688716
-
Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate: Binding mechanism and thermodynamic parameters
-
Ziegler, A. and Seelig, J. (2004) Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate: Binding mechanism and thermodynamic parameters Biophys. J. 86, 254-263
-
(2004)
Biophys. J.
, vol.86
, pp. 254-263
-
-
Ziegler, A.1
Seelig, J.2
-
66
-
-
14044270161
-
Binding of oligoarginine to membrane lipids and heparan sulfate: Structural and thermodynamic characterization of a cell-penetrating peptide
-
Goncalves, E., Kitas, E., and Seelig, J. (2005) Binding of oligoarginine to membrane lipids and heparan sulfate: Structural and thermodynamic characterization of a cell-penetrating peptide Biochemistry 44, 2692-2702
-
(2005)
Biochemistry
, vol.44
, pp. 2692-2702
-
-
Goncalves, E.1
Kitas, E.2
Seelig, J.3
-
67
-
-
38949116621
-
Thermodynamic studies and binding mechanisms of cell-penetrating peptides with lipids and glycosaminoglycans
-
Ziegler, A. (2008) Thermodynamic studies and binding mechanisms of cell-penetrating peptides with lipids and glycosaminoglycans Adv. Drug Delivery Rev. 60, 580-597
-
(2008)
Adv. Drug Delivery Rev.
, vol.60
, pp. 580-597
-
-
Ziegler, A.1
-
68
-
-
2942581416
-
Protein tyrosine phosphatases in the human genome
-
Alonso, A., Sasin, J., Bottini, N., Friedberg, I., Friedberg, I., Osterman, A., Godzik, A., Hunter, T., Dixon, J., and Mustellin, T. (2004) Protein tyrosine phosphatases in the human genome Cell 117, 699-711
-
(2004)
Cell
, vol.117
, pp. 699-711
-
-
Alonso, A.1
Sasin, J.2
Bottini, N.3
Friedberg, I.4
Friedberg, I.5
Osterman, A.6
Godzik, A.7
Hunter, T.8
Dixon, J.9
Mustellin, T.10
-
69
-
-
46449115901
-
The exploration of macrocycles for drug discovery: An underexploited structural class
-
Driggers, E. M., Hale, S. P., Lee, J., and Terrett, N. K. (2008) The exploration of macrocycles for drug discovery: An underexploited structural class Nat. Rev. Drug Discovery 7, 608-624
-
(2008)
Nat. Rev. Drug Discovery
, vol.7
, pp. 608-624
-
-
Driggers, E.M.1
Hale, S.P.2
Lee, J.3
Terrett, N.K.4
-
70
-
-
79953777824
-
Macrocycles are great cycles: Applications, opportunities, and challenges of synthetic macrocycles in drug discovery
-
Marsault, E. and Peterson, M. L. (2011) Macrocycles are great cycles: Applications, opportunities, and challenges of synthetic macrocycles in drug discovery J. Med. Chem. 54, 1961-2004
-
(2011)
J. Med. Chem.
, vol.54
, pp. 1961-2004
-
-
Marsault, E.1
Peterson, M.L.2
-
71
-
-
80052745646
-
High-throughput screening of one-bead-one-compound libraries: Identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction
-
Liu, T., Qian, Z., Xiao, Q., and Pei, D. (2011) High-throughput screening of one-bead-one-compound libraries: Identification of cyclic peptidyl inhibitors against calcineurin/NFAT interaction ACS Comb. Sci. 13, 537-546
-
(2011)
ACS Comb. Sci.
, vol.13
, pp. 537-546
-
-
Liu, T.1
Qian, Z.2
Xiao, Q.3
Pei, D.4
-
72
-
-
84860183254
-
Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction
-
Dewan, V., Liu, T., Chen, K. M., Qian, Z., Xiao, Y., Kleiman, L., Mahasenan, K. V., Li, C., Matsuo, H., Pei, D., and Musier-Forsyth, K. (2012) Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction ACS Chem. Biol. 7, 761-769
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 761-769
-
-
Dewan, V.1
Liu, T.2
Chen, K.M.3
Qian, Z.4
Xiao, Y.5
Kleiman, L.6
Mahasenan, K.V.7
Li, C.8
Matsuo, H.9
Pei, D.10
Musier-Forsyth, K.11
-
73
-
-
84876727804
-
Inhibition of Ras-effector interactions by cyclic peptides
-
Wu, X., Upadhyaya, P., Villalona-Calero, M. A., Briesewitz, R., and Pei, D. (2013) Inhibition of Ras-effector interactions by cyclic peptides Med. Chem. Commun. 4, 378-382
-
(2013)
Med. Chem. Commun.
, vol.4
, pp. 378-382
-
-
Wu, X.1
Upadhyaya, P.2
Villalona-Calero, M.A.3
Briesewitz, R.4
Pei, D.5
-
74
-
-
34250353838
-
Quantative comparison of the telative cell permeability of cyclic and linear peptides
-
Kwon, Y.-U. and Kodadek, T. (2007) Quantative comparison of the telative cell permeability of cyclic and linear peptides Chem. Biol. 14, 671-677
-
(2007)
Chem. Biol.
, vol.14
, pp. 671-677
-
-
Kwon, Y.-U.1
Kodadek, T.2
-
75
-
-
33644644973
-
Testing the conformational hypothesis of passive membrane permeability using synthetic cyclic peptide diastereomers
-
Rezai, T., Yu, B., Millhauser, G. L., Jacobson, M. P., and Lokey, R. S. (2006) Testing the conformational hypothesis of passive membrane permeability using synthetic cyclic peptide diastereomers J. Am. Chem. Soc. 128, 2510-2511
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 2510-2511
-
-
Rezai, T.1
Yu, B.2
Millhauser, G.L.3
Jacobson, M.P.4
Lokey, R.S.5
-
76
-
-
57349171593
-
N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
-
Chatterjee, J., Gilon, C., Hoffman, A., and Kessler, H. (2008) N-Methylation of Peptides: A New Perspective in Medicinal Chemistry Acc. Chem. Res. 41, 1331-1342
-
(2008)
Acc. Chem. Res.
, vol.41
, pp. 1331-1342
-
-
Chatterjee, J.1
Gilon, C.2
Hoffman, A.3
Kessler, H.4
-
77
-
-
79952957889
-
Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2
-
Ren, L., Chen, X., Luechapanichkul, R., Selner, N. G., Meyer, T. M., Wavreille, A. S., Chan, R., Iorio, C., Zhou, X., Neel, B. G., and Pei, D. (2011) Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2 Biochemistry 50, 2339-2356
-
(2011)
Biochemistry
, vol.50
, pp. 2339-2356
-
-
Ren, L.1
Chen, X.2
Luechapanichkul, R.3
Selner, N.G.4
Meyer, T.M.5
Wavreille, A.S.6
Chan, R.7
Iorio, C.8
Zhou, X.9
Neel, B.G.10
Pei, D.11
-
78
-
-
13144305065
-
Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells
-
LaMontagne, K. R., Jr., Hannon, G., and Tonks, N. K. (1998) Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells Proc. Natl. Acad. Sci. U.S.A. 95, 14094-14099
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14094-14099
-
-
Lamontagne, Jr.K.R.1
Hannon, G.2
Tonks, N.K.3
-
79
-
-
77958581350
-
Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs
-
Nguyen, L. T., Chau, J. K., Perry, N. A., de Boer, L., Zaat, S. A. J., and Vogel, H. J. (2010) Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs PLoS One 5, e12684
-
(2010)
PLoS One
, vol.5
, pp. 12684
-
-
Nguyen, L.T.1
Chau, J.K.2
Perry, N.A.3
De Boer, L.4
Zaat, S.A.J.5
Vogel, H.J.6
|