Enantioselective total syntheses of fr901464 and spliceostatin a and evaluation of splicing activity of key derivatives

Journal of Organic Chemistry

Volumn 79, Issue 12, 2014, Pages 5697-5709

  Ghosh, Arun K ^a   Chen, Zhi Hua ^a   Effenberger, Kerstin A ^b   Jurica, Melissa S ^b  

^a PURDUE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; ADDITION REACTIONS; CELL CULTURE;

ANTICANCER ACTIVITIES; DIASTEREO-SELECTIVITY; DIFFERENT SUBSTRATES; ENANTIOSELECTIVE SYNTHESIS; ENANTIOSELECTIVE TOTAL SYNTHESIS; OPTICALLY ACTIVE ALCOHOLS; REACTION CONDITIONS; REDUCTIVE AMINATION;

ENANTIOSELECTIVITY;

ALCOHOL; CHEMICALS AND DRUGS; FR 901464; GLYCERALDEHYDE; SPLICEOSTATIN A; UNCLASSIFIED DRUG; ALKENE; PROPYLENE; PYRAN DERIVATIVE; SPIRO COMPOUND;

ACETYLATION; AMIDATION; AMINATION; ARTICLE; CATALYST; CONTROLLED STUDY; DIASTEREOISOMER; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOSELECTIVITY; HYDROGENATION; IN VITRO STUDY; MICHAEL ADDITION; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; RNA SPLICING; STEREOISOMERISM; SYNTHESIS; TUMOR CELL LINE;

ALKENES; CATALYSIS; CELL LINE, TUMOR; HUMANS; MOLECULAR STRUCTURE; PYRANS; RNA SPLICING; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 84903147933     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo500800k     Document Type: Article

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